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Computational Modeling of Voice Production Using Excised Canine Larynx.

Weili Jiang, Charles Farbos de Luzan, Xiaojian Wang, Liran Oren, Sid M Khosla, Qian Xue, Xudong Zheng,

A combined experimental-numerical work was conducted to comprehensively validate a subject-specific continuum model of voice production in larynx using excised canine laryngeal experiments. The computational model is a coupling of the Navier-Stokes equations for glottal flow dynamics and a finite element model of vocal fold dynamics. The numerical simulations employed ... Read more >>

J Biomech Eng (Journal of biomechanical engineering)
[2022, 144(2):]

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Numerical Investigation of Spinal Cord Injury After Flexion-Distraction Injuries at the Cervical Spine.

Marie-Hélène Beauséjour, Eric Wagnac, Pierre-Jean Arnoux, Jean-Marc Mac Thiong, Yvan Petit,

Flexion-distraction injuries frequently cause traumatic cervical spinal cord injury (SCI). Post-traumatic instability can cause aggravation of the secondary SCI during patient care. However, there is little information on how the pattern of disco-ligamentous injury affects the SCI severity and mechanism. This study objective was to analyze how posterior disco-ligamentous injuries ... Read more >>

J Biomech Eng (Journal of biomechanical engineering)
[2022, 144(1):]

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The ulnar collateral ligament loading paradox between in-vitro and in-vivo studies on baseball pitching (narrative review).

Bart Van Trigt, Liset W Vliegen, Ton Ajr Leenen, DirkJan Hej Veeger,

Ulnar collateral ligament (UCL) weakening or tears occur in 16% of professional baseball pitchers. To prevent players from sustaining a UCL injury, it is important to understand the relationship between the UCL properties and elbow stabilizers with the load on the UCL during pitching. In-vitro studies showed that the ultimate ... Read more >>

Int Biomech (International biomechanics)
[2021, 8(1):19-29]

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Detection of knee wobbling as a screen to identify athletes who may be at high risk for ACL injury.

Akino Aoki, Satoshi Kubota, Kosuke Morinaga, Naiquan Nigel Zheng, Shangcheng Sam Wang, Kazuyoshi Gamada,

This study developed a method to detect knee wobbling (KW) at low knee flexion. KW consists of quick uncontrollable medio-lateral knee movements without knee flexion, which may indicate a risk of ACL injury. Ten female athletes were recorded while performing slow, single-leg squats. Using motion capture data, the ratio of ... Read more >>

Int Biomech (International biomechanics)
[2021, 8(1):30-41]

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Differences between recorded diagnoses of patients of an emergency department and office-hours primary care doctors: a register-based study in a Finnish town.

Mika Lehto, Katri Mustonen, Marko Raina, Timo Kauppila,

To determine the extent to which it is possible to provide continuity of primary care for those who visit Emergency Departments (EDs) we studied how recorded diagnoses in primary care differ, depending on whether the patient is met in an ED or a primary care office-hours practice. In the present, ... Read more >>

Int J Circumpolar Health (International journal of circumpolar health)
[2021, 80(1):1935593]

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Parathyroid hormone-related protein inhibits nitrogen-containing bisphosphonate-induced apoptosis of human periodontal ligament fibroblasts by activating MKP1 phosphatase.

Di Liu, Juan Du, Jing Sun, Minqi Li,

Massive production of reactive oxygen species (ROS) in human periodontal ligament fibroblasts (HPdLFs) by nitrogen-containing bisphosphonates (BPs) is the main factor causing BP-related osteonecrosis of the jaw. Further, oxidative stress and apoptosis of fibroblasts induced by ROS are closely associated with the activation of MAPK. Parathyroid hormone-related protein (PTHrP) can ... Read more >>

Bioengineered (Bioengineered)
[2021, 12(1):1997-2006]

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Cullin3 aggravates the inflammatory response of periodontal ligament stem cells via regulation of SHH signaling and Nrf2.

Wanhong Chen, Jiangling Su, Shixiong Cai, Chun Shi,

It is found that the activation of Sonic Hedgehog (SHH) signaling pathway is related to the degree of inflammation in patients suffering from periodontitis. Cullin3 (CUL3), an important ubiquitin ligase, can control SHH signaling. In this study, we were dedicated to clarify the roles of SHH and CUL3 in <i>P. ... Read more >>

Bioengineered (Bioengineered)
[2021, 12(1):3089-3100]

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Enhancement of DUSP14 (dual specificity phosphatase 14) limits osteoarthritis progression by alleviating chondrocyte injury, inflammation and metabolic homeostasis.

Zandong Zhao, Jie Yang, Liang Zhang, Yunping Zhou,

Osteoarthritis (OA) is a proverbial inflammatory degenerative joint disease associated with the acceleration of the aging process and is characterized by chondrocyte injury and articular cartilage degradation. Dual-specificity phosphatase 14 (Dusp14), a common member of the DUSP family, has been implicated in multiple inflammatory diseases and bone loss. Nevertheless, the ... Read more >>

Bioengineered (Bioengineered)
[2021, 12(1):7495-7507]

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Mechanosensory and mechanotransductive processes mediated by ion channels in articular chondrocytes: Potential therapeutic targets for osteoarthritis.

Kun Zhang, Lifu Wang, Zhongcheng Liu, Bin Geng, Yuanjun Teng, Xuening Liu, Qiong Yi, Dechen Yu, Xiangyi Chen, Dacheng Zhao, Yayi Xia,

Articular cartilage consists of an extracellular matrix including many proteins as well as embedded chondrocytes. Articular cartilage formation and function are influenced by mechanical forces. Hind limb unloading or simulated microgravity causes articular cartilage loss, suggesting the importance of the healthy mechanical environment in articular cartilage homeostasis and implying a ... Read more >>

Channels (Austin) (Channels (Austin, Tex.))
[2021, 15(1):339-359]

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Validity, Responsiveness, and Reliability of the ACL-QOL in an Adolescent Population.

Meaghan Marien, Mark R Lafave, Laurie A Hiemstra, Sydney Mark Heard, Gregory M Buchko, Sarah Kerslake,

<h4>Background</h4>The anterior cruciate ligament quality of life (ACL-QOL) score is a disease-specific patient-reported outcome measure that assesses patients with ACL deficient and reconstructed knees. The ACL-QOL has demonstrated validity, responsiveness, and reliability in adult populations but has yet to be specifically evaluated in adolescent patients. The purpose of this study ... Read more >>

J Pediatr Orthop (Journal of pediatric orthopedics)
[2021, 41(10):e917-e922]

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LT Ligament Tears.

Gregory K Faucher, Mark Christian Moody,

Lunotriquetral (LT) ligament injuries are uncommon, however, should be considered in patients with ulnar-sided wrist pain. LT injuries are often associated with other injuries but can occur in isolation. Understanding the anatomy and pathomechanics will aid in making the diagnosis. Similar to other injuries, a thorough history and focused physical ... Read more >>

Hand Clin (Hand clinics)
[2021, 37(4):537-543]

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The impact of bilateral facetectomy on the instantaneous helical axis of the functional thoracic spinal unit T4-5 during axial rotation.

Paul Jonathan Roch, Dominik Saul, Nikolai Wüstefeld, Stefan Spiering, Wolfgang Lehmann, Lukas Weiser, Martin Michael Wachowski,

The location of the instantaneous helical axis (IHA) and the impact of the facet joints (FJ) on the kinematics in the thoracic spine remain inconclusive. This study aimed to examine the IHA in the functional spinal unit (FSU) T4-5 during axial rotation in intact conditions and after bilateral facetectomy. Four ... Read more >>

Int Biomech (International biomechanics)
[2021, 8(1):42-53]

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Correction to: Dual-energy CT collagen density mapping of wrist ligaments reveals tissue remodeling in CPPD patients: first results from a clinical cohort.

Katharina Ziegeler, Sophia-Theresa Richter, Sandra Hermann, Kay Geert A Hermann, Bernd Hamm, Torsten Diekhoff,

Skeletal Radiol (Skeletal radiology)
[2021, 50(11):2315]

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Tensile mechanical analysis of anisotropy and velocity dependence of the spinal cord white matter: a biomechanical study.

Norihiro Nishida, Itsuo Sakuramoto, Yoshihiro Fujii, Rudolf Yoga Hutama, Fei Jiang, Junji Ohgi, Yasuaki Imajo, Hidenori Suzuki, Masahiro Funaba, Xian Chen, Takashi Sakai,

In spinal cord injuries, external forces from various directions occur at various velocities. Therefore, it is important to physically evaluate whether the spinal cord is susceptible to damage and an increase in internal stress for external forces. We hypothesized that the spinal cord has mechanical features that vary under stress ... Read more >>

Neural Regen Res (Neural regeneration research)
[2021, 16(12):2557-2562]

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Predicting Anterior Cruciate Ligament Reconstruction Revision: A Machine Learning Analysis Utilizing the Norwegian Knee Ligament Register.

R Kyle Martin, Solvejg Wastvedt, Ayoosh Pareek, Andreas Persson, Håvard Visnes, Anne Marie Fenstad, Gilbert Moatshe, Julian Wolfson, Lars Engebretsen,

Several factors are associated with an increased risk of anterior cruciate ligament (ACL) reconstruction revision. However, the ability to accurately translate these factors into a quantifiable risk of revision at a patient-specific level has remained elusive. We sought to determine if machine learning analysis of the Norwegian Knee Ligament Register ... Read more >>

J Bone Joint Surg Am (The Journal of bone and joint surgery. American volume)
[2021, :]

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Arthroscopic confirmation of femoral button deployment prevents soft tissue interposition in ACL reconstruction

Sylvain Guy, Alessandro Carrozzo, Alexandre Ferreira, Thais Dutra Vieira, Benjamin Freychet, Mathieu Thaunat, Bertrand Sonnery-Cottet,

<h4>Purpose</h4> The purpose of this study was to determine whether direct arthroscopic control of femoral buttons can prevent improper deployment and soft tissue interposition in anterior cruciate ligament (ACL) reconstruction. <h4>Methods</h4> A retrospective analysis of prospectively collected data from the SANTI study group database was performed. All patients who underwent ... Read more >>

Knee Surg Sports Traumatol Arthrosc (Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA)
[2021, :1-8]

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Anatomic basics and technical approaches: sacral preauricular extensions, preauricular sulci and dorsal pubic pits in modern anatomical specimens.

Barbara Maurer-Gesek, Doris Pany-Kucera, Michaela Spannagl-Steiner, Stanislaus Argeny, Julia Gruber, Catharina Mueller, Jakob Nedomansky, Stefan Meng, Andrea Maier, Wolfgang J Weninger,

The aim of this study is the evaluation of three selected osseous pelvic features in modern anatomical specimen - the sacral preauricular extension, the preauricular sulcus and pits on the dorsal side of the pubic bone laterally to the symphysis. The specificity and significance of these features are under debate ... Read more >>

Anthropol Anz (Anthropologischer Anzeiger; Bericht uber die biologisch-anthropologische Literatur)
[2021, :]

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Feasibility of MRI for the evaluation of interosseous ligament vertical segment via subtalar arthroscopy correlation: comparison of 2D and 3D MR images.

Hong-Geun Jung, Sung Gyu Moon, Deuk Young Yoon, Hyemin Jang, Ji Hee Kang,

<h4>Background</h4>Interosseous ligament vertical segment (IOLV) and calcaneofibular ligament (CFL) have been reported to be important in stabilizing the subtalar joint. Unlike CFL, there is not much information regarding the comparison of MRI results with surgical evaluation of IOLV and the comparison between 2D and 3D MRI on IOLV evaluation. The ... Read more >>

BMC Musculoskelet Disord (BMC musculoskeletal disorders)
[2021, 22(1):869]

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The posterior oblique ligament in MRI of acute knee trauma.

Darshana Sanghvi, Ayush Srivastav, Shivika Agrawal, Vasav Nakshiwala,

<h4>Objective</h4>To identify the posterior oblique ligament and assess incidence and patterns of injury to the ligament on MRI of acute knee trauma.<h4>Subjects and methods</h4>One hundred twenty-three MRI studies met the study criteria. For each case, the posterior oblique ligament was identified and scored as injured or normal. Incidence of proximal ... Read more >>

Skeletal Radiol (Skeletal radiology)
[2021, :]

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Adolescents Have Twice the Revision Rate of Young Adults After ACL Reconstruction With Hamstring Tendon Autograft: A Study From the Swedish National Knee Ligament Registry.

Baldur Thorolfsson, Eleonor Svantesson, Thorkell Snaebjornsson, Mikael Sansone, Jon Karlsson, Kristian Samuelsson, Eric Hamrin Senorski,

Previous studies have identified young age as a risk factor for anterior cruciate ligament (ACL) revision. However, few studies have looked separately at pediatric patients and adolescents with regard to outcomes after ACL reconstruction. To determine whether patient age at ACL reconstruction affects the risk of undergoing revision surgery in ... Read more >>

Orthop J Sports Med (Orthopaedic journal of sports medicine)
[2021, 9(10):23259671211038893]

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Sentinel lymph node identification in early stage ovarian cancer: is it still possible after prior tumor resection?

Pim Laven, Roy Kruitwagen, Petra Zusterzeel, Brigitte Slangen, Toon van Gorp, Jochem van der Pol, Sandrina Lambrechts,

<h4>Objective</h4>Sentinel lymph node (SLN) detection in ovarian cancer is feasible when tracers are injected before the pathological ovary is resected. This study aims to investigate whether the SLN identification is also feasible in patients whose ovarian tumor has already been resected with injection of the tracer into the ovarian ligaments ... Read more >>

J Ovarian Res (Journal of ovarian research)
[2021, 14(1):132]

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The relationship between a Segond fracture and meniscus injury in patients with anterior cruciate ligament tears.

Yaxiaer Sulaiman, Jian Li, Gang Chen, Haimiti Abudouaini, Qi Li, Xin Tang,

<h4>Background</h4>Segond fracture may be identified when an anterior cruciate ligament (ACL) tear is diagnosed, and it has historically been considered a sign of significant knee trauma indicating intra-articular injury. There are few studies on the correlation between a Segond fracture and meniscus injury. The purpose of this study was to ... Read more >>

Knee (The Knee)
[2021, 33:193-199]

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The biomechanical effect of the relevant segments after facet-disectomy in different diameters under posterior lumbar percutaneous endoscopes: a three-dimensional finite element analysis.

Yin Shi, Yi-Zhou Xie, Qun Zhou, Yang Yu, Xiao-Hong Fan,

<h4>Objective</h4>To evaluate the biomechanical influence after percutaneous endoscopic lumbar facetectomy in different diameters on segmental range of motion (ROM) and intradiscal pressure (IDP) of the relevant segments by establishing three dimensional finite element (FE) model.<h4>Methods</h4>An intact L3-5 model was successfully constructed from the CT of a healthy volunteer as Model ... Read more >>

J Orthop Surg Res (Journal of orthopaedic surgery and research)
[2021, 16(1):593]

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Periodontal ligament regulatory role in experimental diabetic rat model of parodontium remodelation.

A Petrović, M Trandafilović, G Drevenšek, A Plut, M Drevenšek,

<h4>Background</h4>Diabetes, among multiple systemic harmful health issues, also may deteriorate normal regenerative and reparative functions of periodontium. The aim of this research was to study the role of periodontal ligament in tissue remodeling under the orthodontic appliance stimulation in two rat experimental models (healthy Wistar rats and Goto-Kakizaki,rodent model of ... Read more >>

Folia Morphol (Warsz) (Folia morphologica)
[2021, :]

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Valgus Control Feedback and Taping Improves the Effects of Plyometric Exercises in Women With Dynamic Knee Valgus.

Fereshteh Shams, Malihe Hadadnezhad, Amir Letafatkar, Jennifer Hogg,

<h4>Background</h4>Female athletes are more predisposed to anterior cruciate ligament (ACL) injuries in comparison with their male counterparts. Research on ACL injury prevention strategies has demonstrated beneficial effects of plyometric exercises and feedback (FB) during the exercises. FB has resulted in reductions in vertical ground-reaction force and kinematic risk factors associated ... Read more >>

Sports Health (Sports health)
[2021, :19417381211049805]

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