Full Text Journal Articles in
Journal eNeuro

Advertisement

Find full text journal articles






Neonatal white matter microstructure and emotional development during the pre-school years in children who were born very preterm.

Dana Kanel, Lucy Vanes, Diliana Pecheva, Laila Hadaya, Shona Falconer, Serena Counsell, David Edwards, Chiara Nosarti,

Children born very preterm (<33 weeks of gestation) are at a higher risk of developing socio-emotional difficulties compared to those born at term. In this longitudinal study, we tested the hypothesis that diffusion characteristics of white matter tracts implicated in socio-emotional processing assessed in the neonatal period are associated with ... Read more >>

eNeuro (eNeuro)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Perceptual Fading of a Stabilized Cortical Image: Replication in the Undergraduate Classroom.

Nicole B Massa, Jacob Deck, Michael A Grubb,

Prolonged exposure to a stimulus causes desensitization of cortical neurons and results in perceptual changes. One example of this phenomenon is contrast adaptation, in which perceived differences between light and dark regions of a stimulus decrease. Blakemore, Muncey, and Ridley reported evidence for the "perceptual fading of a stabilized cortical ... Read more >>

eNeuro (eNeuro)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Advertisement

The type 2 diabetes factor methylglyoxal mediates axon initial segment shortening and alters neuronal function at the cellular and network levels.

Ryan B Griggs, Duc V M Nguyen, Leonid M Yermakov, Jeneane M Jaber, Jennae N Shelby, Josef K Steinbrunner, John A Miller, Carlos Gonzalez-Islas, Peter Wenner, Keiichiro Susuki,

Recent evidence suggests that alteration of axon initial segment (AIS) geometry (i.e., length or location along the axon) contributes to CNS dysfunction in neurological diseases. For example, AIS length is shorter in the prefrontal cortex of type 2 diabetic mice with cognitive impairment.To determine the key type 2 diabetes-related factor ... Read more >>

eNeuro (eNeuro)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Beneficial Effects of Transplanted Human Bone Marrow Endothelial Progenitors on Functional and Cellular Components of Blood-Spinal Cord Barrier in ALS Mice.

Svitlana Garbuzova-Davis, Kayla J Boccio, Alexander Llauget, Robert Shell, Surafuale Hailu, Hilmi Mustafa, Jared Ehrhart, Paul R Sanberg, Stanley H Appel, Cesario V Borlongan,

Convincing evidence of blood-spinal cord barrier (BSCB) alterations has been demonstrated in amyotrophic lateral sclerosis (ALS) and barrier repair is imperative to prevent motor neuron dysfunction. We showed benefits of human bone marrow-derived CD34+ cells (hBM34+) and endothelial progenitor cells (hBM-EPCs) intravenous transplantation into symptomatic G93A SOD1 mutant mice on ... Read more >>

eNeuro (eNeuro)
[2021, 8(5):]

Cited: 0 times

View full text PDF listing >>



TMEM16A and TMEM16B Modulate Pheromone-Evoked Action Potential Firing in Mouse Vomeronasal Sensory Neurons.

Andres Hernandez-Clavijo, Nicole Sarno, Kevin Y Gonzalez-Velandia, Rudolf Degen, David Fleck, Jason R Rock, Marc Spehr, Anna Menini, Simone Pifferi,

The mouse vomeronasal system controls several social behaviors. Pheromones and other social cues are detected by sensory neurons in the vomeronasal organ (VNO). Stimuli activate a transduction cascade that leads to membrane potential depolarization, increase in cytosolic Ca<sup>2+</sup> level, and increased firing. The Ca<sup>2+</sup>-activated chloride channels TMEM16A and TMEM16B are ... Read more >>

eNeuro (eNeuro)
[2021, 8(5):]

Cited: 0 times

View full text PDF listing >>



Effects of Cooling Temperatures via Thermal K2P Channels on Regeneration of High-Frequency Action Potentials at Nodes of Ranvier of Rat Aβ-Afferent Nerves.

Hirosato Kanda, Sotatsu Tonomura, Jianguo G Gu,

Temperature-sensitive two-pore domain potassium channels (thermal K2P) are recently shown to cluster at nodes of Ranvier (NRs) and play a key role in action potential (AP) regeneration and conduction on Aβ-afferent nerves. Cooling temperatures affect AP regeneration and conduction on Aβ-afferent nerves but the underlying mechanisms are not completely understood. ... Read more >>

eNeuro (eNeuro)
[2021, 8(5):]

Cited: 0 times

View full text PDF listing >>



Differential Retinoic Acid Signaling in the Hippocampus of Aged Rats with and without Memory Impairment.

Marta U Wołoszynowska-Fraser, Sharyn L Rossi, Jeffrey M Long, Peter J McCaffery, Peter R Rapp,

Retinoic acid (RA), a metabolite of vitamin A, has many physiological functions, and mounting evidence points to important roles in cognition. <i>In vitro</i> experiments indicate that RA is involved in homeostatic synaptic scaling in the hippocampus, which supports overall network stability during learning. It has been previously determined that disrupted ... Read more >>

eNeuro (eNeuro)
[2021, 8(5):]

Cited: 0 times

View full text PDF listing >>



Secreted reporter assay enables quantitative and longitudinal monitoring of neuronal activity.

Ana C Santos, Simone Chiola, Guang Yang, Aleksandr Shcheglovitov, Sungjin Park,

The ability to measure changes in neuronal activity in a quantifiable and precise manner is of fundamental importance to understand neuron development and function. Repeated monitoring of neuronal activity of the same population of neurons over several days is challenging and, typically, low-throughput. Here, we describe a new biochemical reporter ... Read more >>

eNeuro (eNeuro)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Protein Nanoparticles Modified with PDGF-B as a Novel Therapy After Acute Cerebral Infarction.

Soh Takagishi, Koichi Arimura, Masaharu Murata, Katsuma Iwaki, Tomohiro Okuda, Keisuke Ido, Ataru Nishimura, Sayoko Narahara, Takahito Kawano, Koji Iihara,

Treatment options for cerebral infarction beyond the time window of reperfusion therapy are limited, and novel approaches are needed. PDGF-B is considered neuroprotective; however, it is difficult to administer at effective concentrations to infarct areas. Nanoparticles (NPs) are small and stable; therefore, we modified PDGF-B to the surface of naturally ... Read more >>

eNeuro (eNeuro)
[2021, 8(5):]

Cited: 0 times

View full text PDF listing >>



Understanding the significance of the hypothalamic nature of the subthalamic nucleus.

Marie Barbier, Pierre-Yves Risold,

The subthalamic nucleus (STN) is an essential component of the basal ganglia and has long been considered to be a part of the ventral thalamus. However, recent neurodevelopmental data indicated that this nucleus is of hypothalamic origin which is now commonly acknowledged. In this work, we aimed to verify whether ... Read more >>

eNeuro (eNeuro)
[2021, :]

Cited: 0 times

View full text PDF listing >>



The hedgehog signaling pathway is expressed in the adult mouse hypothalamus and modulated by fasting.

Patrick J Antonellis, Staci E Engle, Kathryn M Brewer, Nicolas F Berbari,

The hedgehog signaling pathway is best known for its role in developmental patterning of the neural tube and limb bud. More recently, hedgehog signaling has been recognized for its roles in growth of adult tissues and maintenance of progenitor cell niches. However, the role of hedgehog signaling in fully differentiated ... Read more >>

eNeuro (eNeuro)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Glycogen Synthase Kinase 3 regulates the genesis of displaced retinal ganglion cells.

Elena Kisseleff, Robin J Vigouroux, Catherine Hottin, Sophie Lourdel, Leah Thomas, Parth Shah, Alain Chédotal, Muriel Perron, Anand Swaroop, Jerome E Roger,

Glycogen Synthase Kinase 3 (GSK) proteins (GSK3α and GSK3β) are key mediators of signaling pathways, with crucial roles in coordinating fundamental biological processes during neural development. Here we show that the complete loss of GSK3 signaling in mouse retinal progenitors leads to microphthalmia with broad morphological defects. A single wild-type ... Read more >>

eNeuro (eNeuro)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Somatostatin Interneurons of the Insula Mediate QR2 Dependent Novel Taste Memory Enhancement.

Nathaniel L Gould, Sailendrakumar Kolatt Chandran, Haneen Kayyal, Efrat Edry, Kobi Rosenblum,

Forming long term memories is crucial for adaptive behavior and survival in changing environments. The molecular consolidation processes which underlie the formation of these long term memories are dependent on protein synthesis in excitatory and SST expressing neurons. A centrally important, parallel process to this involves the removal of the ... Read more >>

eNeuro (eNeuro)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Distinct Opsin 3 (Opn3) Expression in the Developing Nervous System during Mammalian Embryogenesis.

Wayne I L Davies, Soufien Sghari, Brian A Upton, Christoffer Nord, Max Hahn, Ulf Ahlgren, Richard A Lang, Lena Gunhaga,

Opsin 3 (<i>Opn3</i>) is highly expressed in the adult brain, however, information for spatial and temporal expression patterns during embryogenesis is significantly lacking. Here, an <i>Opn3</i>-eGFP reporter mouse line was used to monitor cell body expression and axonal projections during embryonic and early postnatal to adult stages. By applying 2D ... Read more >>

eNeuro (eNeuro)
[2021, 8(5):]

Cited: 0 times

View full text PDF listing >>



MEYE: Web-app for translational and real-time pupillometry.

Raffaele Mazziotti, Fabio Carrara, Aurelia Viglione, Leonardo Lupori, Luca Lo Verde, Alessandro Benedetto, Giulia Ricci, Giulia Sagona, Giuseppe Amato, Tommaso Pizzorusso,

Pupil dynamics alterations have been found in patients affected by a variety of neuropsychiatric conditions, including autism. Studies in mouse models have used pupillometry for phenotypic assessment and as a proxy for arousal. Both in mice and humans, pupillometry is non-invasive and allows for longitudinal experiments supporting temporal specificity, however, ... Read more >>

eNeuro (eNeuro)
[2021, :]

Cited: 0 times

View full text PDF listing >>



A Direct Comparison of Afferents to the Rat Anterior Thalamic Nuclei and Nucleus Reuniens: Overlapping But Different.

Mathias L Mathiasen, Andrew J D Nelson, Eman Amin, Shane M O'Mara, John P Aggleton,

Both nucleus reuniens and the anterior thalamic nuclei are densely interconnected with medial cortical and hippocampal areas, connections that reflect their respective contributions to learning and memory. To better appreciate their comparative roles, pairs of different retrograde tracers were placed in these two thalamic sites in adult rats. Both thalamic ... Read more >>

eNeuro (eNeuro)
[2021, 8(5):]

Cited: 0 times

View full text PDF listing >>



Isoform-specific reduction of the basic helix-loop-helix transcription factor TCF4 levels in Huntington's disease.

Kaja Nurm, Mari Sepp, Carla Castany-Pladevall, Jordi Creus-Muncunill, Jürgen Tuvikene, Alex Sirp, Hanna Vihma, Derek J Blake, Esther Perez-Navarro, Tõnis Timmusk,

Huntington's disease (HD) is an inherited neurodegenerative disorder with onset of characteristic motor symptoms at midlife, preceded by subtle cognitive and behavioral disturbances. Transcriptional dysregulation emerges early in the disease course and is considered central to HD pathogenesis. Using wild-type and HD knock-in mouse striatal cell lines we observed a ... Read more >>

eNeuro (eNeuro)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Exposure to Sleep, Rest, or Exercise Impacts Skill Memory Consolidation but so Too Can a Challenging Practice Schedule.

Taewon Kim, David L Wright,

When discussing procedural learning, it is now routine to consider both online and offline influences for skill acquisition. This is because it is commonly assumed that the evolution of a novel skill memory continues well after practice is over. Indeed, factors impacting offline contributions to skill memory development such as ... Read more >>

eNeuro (eNeuro)
[2021, 8(5):]

Cited: 0 times

View full text PDF listing >>



Prenatal androgen treatment does not alter the firing activity of hypothalamic arcuate kisspeptin neurons in female mice.

Amanda G Gibson, Jennifer Jaime, Laura L Burger, Suzanne M Moenter,

Neuroendocrine control of reproduction is disrupted in many individuals with polycystic ovary syndrome, who present with increased luteinizing hormone (LH), and presumably gonadotropin-releasing hormone (GnRH), release frequency, and high androgen levels. Prenatal androgenization (PNA) recapitulates these phenotypes in primates and rodents. Female offspring of mice injected with dihydrotestosterone (DHT) on ... Read more >>

eNeuro (eNeuro)
[2021, :]

Cited: 0 times

View full text PDF listing >>



The Consistency of Prior Movements Shapes Locomotor Use-Dependent Learning.

Jonathan M Wood, Susanne M Morton, Hyosub E Kim,

Repetition is an indispensable component of motor skill acquisition. However, it is unknown how consistent repeated movement patterns must be to engage an implicit "use-dependent" learning mechanism. In this Registered Report, we tackled this question through a combination of computational modeling, simulations, and behavioral experiments involving visually-guided treadmill walking. Our ... Read more >>

eNeuro (eNeuro)
[2021, 8(5):]

Cited: 0 times

View full text PDF listing >>



Language Tasks and the Network Control Role of the Left Inferior Frontal Gyrus.

John D Medaglia, Denise Y Harvey, Apoorva S Kelkar, Jared P Zimmerman, Joely A Mass, Danielle S Bassett, Roy H Hamilton,

Recent work has combined cognitive neuroscience and control theory to make predictions about cognitive control functions. Here, we test a link between whole-brain theories of semantics and the role of the left inferior frontal gyrus (LIFG) in controlled language performance using network control theory (NCT), a branch of systems engineering. ... Read more >>

eNeuro (eNeuro)
[2021, 8(5):]

Cited: 0 times

View full text PDF listing >>



Phase Gradients and Anisotropy of the Suprachiasmatic Network: Discovery of Phaseoids.

Tomoko Yoshikawa, Scott Pauls, Nicholas Foley, Alana Taub, Joseph LeSauter, Duncan Foley, Ken-Ichi Honma, Sato Honma, Rae Silver,

Biological neural networks operate at several levels of granularity, from the individual neuron to local neural circuits to networks of thousands of cells. The daily oscillation of the brain's master clock in the suprachiasmatic nucleus (SCN) rests on a yet to be identified network of connectivity among its ∼20,000 neurons. ... Read more >>

eNeuro (eNeuro)
[2021, 8(5):]

Cited: 0 times

View full text PDF listing >>



Forebrain Neural Precursor Cells Are Differentially Vulnerable to Zika Virus Infection.

Samantha M Shelton, Alexandra R Soucy, Ronni Kurzion, Ella Zeldich, John H Connor, Tarik F Haydar,

Prenatal exposure to Zika virus (ZIKV) can result in microencephaly and congenital Zika syndrome, although some brain cells and structures are spared by the virus for unknown reasons. Here, a novel murine model of fetal ZIKV infection incorporating intraventricular infection and cell type-specific <i>in utero</i> electroporation (IUE) was used to ... Read more >>

eNeuro (eNeuro)
[2021, 8(5):]

Cited: 0 times

View full text PDF listing >>



Transcranial Direct Current Stimulation above the Medial Prefrontal Cortex Facilitates Decision-Making following Periods of Low Outcome Controllability.

Gábor Csifcsák, Jorunn Bjørkøy, Sarjo Kuyateh, Haakon Reithe, Matthias Mittner,

Recent studies suggest that choice behavior in reinforcement learning tasks is shaped by the level of outcome controllability. In particular, Pavlovian bias (PB) seems to be enhanced under low levels of control, manifesting in approach tendencies toward rewards and response inhibition when facing potential losses. The medial prefrontal cortex (mPFC) ... Read more >>

eNeuro (eNeuro)
[2021, 8(5):]

Cited: 0 times

View full text PDF listing >>



Postdiction: When Temporal Regularity Drives Space Perception through Prestimulus Alpha Oscillations.

Laetitia Grabot, Christoph Kayser, Virginie van Wassenhove,

In postdiction, the last stimulus of a sequence changes the perception of the preceding stimuli. Postdiction has been reported in all sensory modalities, but its neural underpinnings remain poorly understood. In the rabbit illusion, a sequence of nonequidistant stimuli presented isochronously is perceived as equidistantly spaced. This illusion might be ... Read more >>

eNeuro (eNeuro)
[2021, 8(5):]

Cited: 0 times

View full text PDF listing >>



Advertisement


Disclaimer

1.0063 s