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Journal Zhong Nan Da Xue Xue Bao Yi Xue Ban

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Marginal zone lymphoma associated amyloidosis: A case report and literature review.

Yumei Liao, Shenghua Sun, Lihua Xie, Xiaoyan Wang,

The marginal zone lymphoma is a common indolent malignant tumor in the blood system, but the patients with myocardial amyloidosis is rare. In January 2018,a marginal zone lymphoma associated with myocardial amyloidosis was accepted by the Third Xiangya Hospital, Central South University, main complaining of shortness of breath for more ... Read more >>

Zhong Nan Da Xue Xue Bao Yi Xue Ban (Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences)
[2020, 45(3):359-364]

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Unprecedented action has been taken to contain the epidemic of coronavirus disease 2019 in China.

Tong Wu, Erya Hu, Wenhui Zeng, Hanqi Zhang, Xiaoran Xue, Jian Ma,

The current outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, China, has posed significant threats to international health. By Feb. 20, 2020, 74 576 cases have been confirmed and over 2 118 deaths have reported in the Chinese mainland. Chinese administrations have carried out immediate and prompt measures to stop ... Read more >>

Zhong Nan Da Xue Xue Bao Yi Xue Ban (Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences)
[2020, 45(3):334-337]

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Neoadjuvant chemotherapy efficacy and prognostic factors in 187 cervical cancer patients with IB2 and IIA2 stage.

Tingting Zou, Chunying Zheng, Zhibang Zhang, Li Yu, Chun Fu,

OBJECTIVES:To investigate the efficacy and prognostic factors for patients receiving neoadjuvant chemotherapy (NACT) before operation in stage IB2 and IIA2 cervical cancer. METHODS:A total of 187 patients with IB2 and IIA2 cervical cancer who received NACT combined surgery from January 2005 to January 2016 were enrolled. All patients were divided ... Read more >>

Zhong Nan Da Xue Xue Bao Yi Xue Ban (Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences)
[2020, 45(3):297-304]

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First CT characteristic appearance of patients with coronavirus disease 2019.

Wei Nie, Zhichao Feng, Xiaowen Mao, Pengfei Rong, Wei Wang, Qi Liang,

OBJECTIVES:To investigate imaging features of the coronavirus disease 2019 (COVID-19), and to provide concrete evidences for diagnosis of COVID-19. METHODS:Imaging data of the first chest CT examination and clinical data (age, sex, clinical history, epidemiological history, and laboratory tests) of 163 patients with COVID-19 from 2 hospitals were collected for ... Read more >>

Zhong Nan Da Xue Xue Bao Yi Xue Ban (Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences)
[2020, 45(3):262-268]

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Design, validation, and clinical practice of standardized imaging diagnostic report for COVID-19.

Tianming Wang, Zeng Xiong, Hui Zhou, Weijun Luo, Haixiong Tang, Jinkang Liu,

OBJECTIVES:To design a standardized imaging diagnostic reporting mode for screening coronavirus disease 2019 (COVID-19), and to prospectively verify its effectiveness in clinical practice. METHODS:A new classification and standardized imaging diagnosis report mode of viral pneumonia was established by studying and summarizing the imaging findings of various kinds of viral pneumonia, ... Read more >>

Zhong Nan Da Xue Xue Bao Yi Xue Ban (Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences)
[2020, 45(3):229-235]

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Myeloid neoplasm with the abnormality of PDGFRB gene secondary interstitial pneumonia: A case report.

Guiqian Liu, Ruoyun Ouyang, Ping Chen, Ting Liu, Li Zhou, Chong Shen,

We report a case of myeloid neoplasm with the abnormality of PDGFRB gene secondary interstitial pneumonia. A 66-year-old male complained dry cough and shortness of breath after regular activities. Two years ago, high-resolution computerized tomography (HRCT) showed interstitial lung diseases, and no clear etiology was found. At that time, the ... Read more >>

Zhong Nan Da Xue Xue Bao Yi Xue Ban (Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences)
[2020, 45(3):345-348]

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High glucose up-regulates MMP-1 expression in endothelial cells via mTORC2-PKM2 pathway.

Lei Tang, Yizhou Xu, Xiaojing Liu, Ruifang Chen, Ying Li,

OBJECTIVES:To investigate the role of pyruvate kinase isozyme type M2 (PKM2) in regulating the expression of matrix metalloproteinase-1 (MMP-1) in human umbilical vein endothelial cells (HUVECs) under high glucose exposure and the underlying mechanisms. METHODS:HUVECs were exposed to concentration gradient (5.5, 15.0, 30.0 mmol/L) of D-glucose for 72 h. Western ... Read more >>

Zhong Nan Da Xue Xue Bao Yi Xue Ban (Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences)
[2020, 45(3):305-313]

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Value of CT application in the screening,diagnosis,and treatment of COVID-19.

Ge Li, Zeng Xiong, Hui Zhou, Jiangping Xie, Wei Chen, Moling Zhou, Zhiming Zhu, Gaofeng Zhou, Jinkang Liu,

The coronavirus disease 2019 (COVID-19) has attracted extensive attention all around the world recently. Early screening, early diagnosis, early isolation, and early treatment remain the most effective prevention and control measures. Computed tomography (CT) plays a vital role in the screening, diagnosis, treatment, and follow-up of COVID-19, especially in the ... Read more >>

Zhong Nan Da Xue Xue Bao Yi Xue Ban (Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences)
[2020, 45(3):269-274]

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Chest CT findings and clinical features of coronavirus disease 2019 in children.

Zheng Zhong, Xingzhi Xie, Wei Huang, Wei Zhao, Qizhi Yu, Jun Liu,

OBJECTIVES:To describe the CT features and clinical characteristics of pediatric patients with coronavirus disease 2019 (COVID-19). METHODS:A total of 9 COVID-19 infected pediatric patients were included in this study. Clinical history, laboratory examination, and detailed CT imaging features were analyzed. All patients underwent the first CT scanning on the same ... Read more >>

Zhong Nan Da Xue Xue Bao Yi Xue Ban (Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences)
[2020, 45(3):236-242]

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Phrenic nerve injury during right inferior pulmonary vein ablation with the second-generation cryoballoon: A report of 2 cases and literature review.

Xianxian Zhou, Xuping Li, Hui Tian, Zhihong Wu, Zhenjiang Liu, Hui Yang, Qiming Liu, Shenghua Zhou,

The performance of the second-generation cryoballoon has been greatly improved compared to the first-generation.But it has not reduced the incidence of phrenic nerve injury, and even increased the incidence of this complication during ablation of the right inferior pulmonary vein. Two cases of phrenic nerve injury occurred when right inferior ... Read more >>

Zhong Nan Da Xue Xue Bao Yi Xue Ban (Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences)
[2020, 45(3):354-358]

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Effect of sleeve gastrectomy on gastroesophageal reflux in patients with metabolic syndrome.

Linli Sun, Zhihong Su, Pengzhou Li, Weizheng Li, Shaihong Zhu, Liyong Zhu,

OBJECTIVES:To investigate the incidence of gastroesophageal reflux disease (GERD) after sleeve gastrectomy and the effect of sleeve gastrectomy in treating the symptom of gastroesophageal reflux in patients with metabolic syndrome. METHODS:We retrospectively analyzed 60 patients with metabolic syndrome who received laparoscopy sleeve gastrectomy in the Department of Bariatric and Metabolic ... Read more >>

Zhong Nan Da Xue Xue Bao Yi Xue Ban (Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences)
[2020, 45(3):328-333]

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Effects of propofol on invasion and migration of colon cancer cells and JAK2/STAT3 signaling pathway.

Bing Liang, Tieli Dong,

OBJECTIVES:To investigate the effect of propofol on invasion and migration of human colon cancer cell line SW480 and the JAK2/STAT3 pathway. METHODS:Human colon cancer cell line SW480 was divided into a control group, 3 propofol treatment groups (with 2, 4 and 8 μg/mL propofol treatment, respectively), and a propofol+colivelin group. ... Read more >>

Zhong Nan Da Xue Xue Bao Yi Xue Ban (Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences)
[2020, 45(3):290-296]

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Clinical and CT imaging features between the first nucleic acid-negative and first nucleic acid-positive COVID-19 patients.

Sha Li, Jinkang Liu, Zeng Xiong, Weijun Luo, Haixiong Tang, Wanxiang Pend, Ziyu Hu, Huijuan Feng, Qunbai Xie, Ben Liu, Weihua Liao, Hui Zhou,

OBJECTIVES:To investigate the role of chest CT for the diagnostic work-up for patients with suspected infection of coronavirus disease 2019 (COVID-19). METHODS:The clinical data and imaging findings of the first nucleic acid-negative COVID-19 patients were analyzed and compared with the first nucleic acid-positive patients. RESULTS:Compared with the first nucleic acid-positive ... Read more >>

Zhong Nan Da Xue Xue Bao Yi Xue Ban (Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences)
[2020, 45(3):257-261]

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Imaging examination, diagnosis, and control and prevention of nosocomial infection for coronavirus disease 2019: Expert consensus of Hunan radiologist.

JinKang Liu, Wei Wang,

The outbreak of coronavirus disease 2019 (COVID-19) is a huge threat to global public health because it develops rapidly. There is no specific treatment so far. Chest imaging examination is an important auxiliary examination method in diagnosis of COVID-19. To further standardize the imaging examination and diagnosis of COVID-19, Hunan ... Read more >>

Zhong Nan Da Xue Xue Bao Yi Xue Ban (Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences)
[2020, 45(3):221-228]

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Research progress in relation of Helicobacter pylori infection with pregnancy-related diseases and adverse pregnancy outcomes.

Bai Zhou, Fen Wang,

Helicobacter pylori (Hp) is a Gram-negative microaerobic bacterium, which is parasitic on gastric mucosa and is associated with the pathogenesis of chronic gastritis, gastric ulcer, gastric cancer and other gastric diseases. Meanwhile, the Hp infection is related with pregnancy-related diseases, pregnancy outcomes, and the health status of offspring, such as ... Read more >>

Zhong Nan Da Xue Xue Bao Yi Xue Ban (Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences)
[2020, 45(3):338-344]

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Effect of deletion of SUMOylation on dendritic cell function in septic mice and its role in sepsis.

Guyi Wang, Fei Yang, Tiantian Gao, Diling Wu, Jia Huang, Jinxiu Li,

OBJECTIVES:To investigate the effect of deletion of small ubiquitin-like modifier (SUMO) on the function of dendritic cells (DC) in septic mice and its role in sepsis. METHODS:Septic models of DC-specific ubiquitin-conjugating enzyme 9 (UBC9) deficient (UBC9ΔDC) mice and wild type (WT) mice with cecal ligation and puncture (CLP) were established. ... Read more >>

Zhong Nan Da Xue Xue Bao Yi Xue Ban (Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences)
[2020, 45(3):314-321]

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A family outbreak of coronavirus disease 2019.

Weijun Luo, Zeng Xiong, Haixiong Tang, Hui Zhou,

Although continuous outbreak of coronavirus disease 2019, it has been widely reported, there were few reports regarding family cases. We reported a group of family cluster outbreak cases confirmed in Xiangya Hospital, Central South University, China, and their clinical and image characteristics have been analyzed in order to provide reference ... Read more >>

Zhong Nan Da Xue Xue Bao Yi Xue Ban (Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences)
[2020, 45(3):275-279]

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CT imaging features and image evolution characteristics of coronavirus disease 2019.

Ming Li, Wanxiang Peng, Miaomiao Chen, Qichao Zhu, Xia Zou, Xiaoli Long,

OBJECTIVES:To analyze the imaging features of coronavirus disease 2019 (COVID-19) in different periods, and summarize the characteristics with itsdevelopment. METHODS:We retrospectively analyzed the CT image data of COVID-19 patients diagnosed by nucleic acid test and CT examination in 57 patients in Zhuzhou Central Hospital and Zhuzhou First People's Hospital, and ... Read more >>

Zhong Nan Da Xue Xue Bao Yi Xue Ban (Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences)
[2020, 45(3):243-249]

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Treatment-induced neuropathy in diabetes: A report of 2 cases and literature review.

Jingjing Yuan, Ke Chen, Shaoli Zhao, Zhaohui Mo,

Treatment-induced neuropathy is an distinct, acute form of neuropathic pain which often occur shortly after initiation of intensive glycemic control and is characterized by excruciating neuropathic pain. It is a rare form of diabetic neuropathy and easy to be misdiagnosed. Clinical characteristics were analyzed based on two cases of treatment-induced ... Read more >>

Zhong Nan Da Xue Xue Bao Yi Xue Ban (Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences)
[2020, 45(3):349-353]

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Clinical study on ixazomib in the treatment of multiple myeloma.

Yanjuan He, Kaixuan Zhang, Lang Zou, Shuping Chen, Duanfeng Jiang, Jian Hu, Yan Zhu,

OBJECTIVES:To evaluate the efficacy and safety of ixazomib in the treatment of multiple myeloma. METHODS:A total of 43 patients with multiple myeloma were given ixazomib-based chemotherapy, including 16 patients with relapsed/refractory multiple myeloma (RRMM group), 27 patients newly diagnosed multiple myeloma with serious adverse events initially treated with bortezomib (conversion ... Read more >>

Zhong Nan Da Xue Xue Bao Yi Xue Ban (Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences)
[2020, 45(3):322-327]

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Role of miR-92a-3p/PTEN axis in regulation of pancreatic cancer cell proliferation and metastasis.

Yu Liu, Qing Hu, Jingjing Ao, Hongling Li, Meiliang Li,

OBJECTIVES:To explore the effect of miR-92a-3p on the proliferation and metastasis of pancreatic cancer cells via targeting phosphatase and tension homolog deleted on chromosome ten (PTEN). METHODS:MiR-92a-3p expression and PTEN protein levels were quantified in a normal pancreatic cells (HPDE6-C7) and 5 pancreatic cancer cell lines (Panc-1, BxPC-3, AsPC-1,MIA Paca-2, ... Read more >>

Zhong Nan Da Xue Xue Bao Yi Xue Ban (Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences)
[2020, 45(3):280-289]

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Multistage CT features of coronavirus disease 2019.

Zheng Zhong, Ying Hu, Qizhi Yu, Yuxin Li, Peng Li, Wei Huang, Jingui Liu, Jun Liu, Xingzhi Xie, Wei Zhao,

OBJECTIVES:To determine imaging features of coronavirus disease 2019 (COVID-19) in different stages, and to provide foundations for early diagnosis and treatment. METHODS:CT image data of 187 COVID-19 patients were analyzed in the period of hospitalization. CT scanning was performed on admission and repeated every 3 days. The improvement time of ... Read more >>

Zhong Nan Da Xue Xue Bao Yi Xue Ban (Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences)
[2020, 45(3):250-256]

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Influence of dietary fiber on chronic kidney disease: Base on the gut-kidney axis theory.

Xiaohui Xie, Siyuan Dai, Yanling Dai, Jianping Ning,

Chronic kidney disease (CKD) can result in alteration of intestinal flora and damage of intestinal barrier function. Intestinal dysbios is contributes to the generation of colon-derived uremic solutes and the translocation of bacteria and endotoxins from gut lumen into the bloodstream, subsequently increasing uremic toxicity and triggering systemic inflammation, which ... Read more >>

Zhong Nan Da Xue Xue Bao Yi Xue Ban (Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences)
[2020, 45(2):193-197]

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Relationship between the incidence of rosacea and drinking or smoking in China.

Yaling Wang, Zhixiang Zhao, Fangfen Liu, Hongfu Xie, Ji Li, Ben Wang,

OBJECTIVES:To explore the relationship between the incidence of rosacea and drinking, smoking, gender or age, and to provide some basis for the diagnosis, treatment and mechanism of rosacea. METHODS:A total of 1 180 patients with rosacea and 1 008 non-rosacea patients diagnosed in the Department of Dermatology of Xiangya Hospital ... Read more >>

Zhong Nan Da Xue Xue Bao Yi Xue Ban (Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences)
[2020, 45(2):165-168]

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Risk factors for recurrence of paroxysmal atrial fibrillation after second-generation of cryoballoon ablation.

Xianxian Zhou, Xuping Li, Hui Tian, Zhihong Wu, Zhenjiang Liu, Hui Yang, Qiming Liu, Shenghua Zhou,

OBJECTIVES:To analyze the risk factors for recurrence of paroxysmal atrial fibrillation (PAF) after the second-generation of cryoballoon ablation (CBA). METHODS:A total of 67 patients with PAF, who underwent CBA treatment from March 2017 to June 2018, were selected from the Department of Cardiology, Second Xiangya Hospital of Central South University. ... Read more >>

Zhong Nan Da Xue Xue Bao Yi Xue Ban (Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences)
[2020, 45(2):134-138]

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