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Cerebral hemodynamic alterations in patients with Covid-19.

Alİ Riza Sonkaya, Bİlgİn ÖztÜrk, Ömer KaradaŞ,

BACKGROUND/AIM:Coronavirus 2019 disease (Covid-19) was first seen in December 2019 and afterwards it became a pandemic. Several systemic involvements have been reported in Covid-19 patients. In this study, it was aimed to investigate the cerebrovascular hemodynamics in patients with Covid-19. MATERIALS AND METHODS:The sample of this study was conducted on ... Read more >>

Turk J Med Sci (Turkish journal of medical sciences)
[2020, :]

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An evaluation of suspected cases of Hantavirus infection admitted to a tertiary care university hospital in Düzce, Turkey, between 2012 and 2018.

Nevİn İnce, KÜrŞad ÖneÇ, Tansu Sav, Mehmet Alİ Sungur, Dİlek MenemenlİoĞlu,

BACKGROUND/AIM:Hantavirus is a rodent borne zoonosis caused by the members of the virus family Bunyaviridae, genus Hantavirus. In this study, we aimed to determine the role of peripheral blood leukocyte ratio in differential diagnosis of Hantavirus disease. MATERIALS AND METHODS:The medical records of patients at the Düzce University Medical Faculty ... Read more >>

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[2020, :]

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Can urinary biomarkers predict acute kidney injury in newborns with critical congenital heart disease?

ÖzgÜn Uygur, Özge Altun KÖroĞlu, ReŞİt ErtÜrk Levent, Eser SÖzmen, Firat Ergİn, YÜksel Atay, Mehmet Yalaz, Mete AkisÜ, NİlgÜn KÜltÜrsay,

BACKGROUND/AIM:Congenital heart disease (CHD) is the most common congenital malformation group and is the leading cause of newborn mortality in developed countries. Most of the infants with CHD develop pre-operative or postoperative acute kidney injury (AKI). AKI may develop before the serum creatinine rise and oliguria. Urinary biomarkers such as ... Read more >>

Turk J Med Sci (Turkish journal of medical sciences)
[2020, :]

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Risk factors predicting the development of diabetes mellitus and metabolic syndrome following gestational diabetes mellitus.

BÜlent Can, Sema Ciftci, Gulsah Yenidunya Yalin, Nevin Dinccag,

AIM:To determine risk factors associated with the development of insulin resistance, type 2 diabetes mellitus (T2DM), and metabolic syndrome (MetS) in gestational diabetes mellitus (GDM) patients 10 years after delivery. METHODS:Medical records of patients with former GDM were screened. Eligible patients were invited to the hospital to obtain information about ... Read more >>

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[2020, :]

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The effect of induction loop system use training on adults with hearing aids.

Merve Burcu Özay, HÜseyİn Özay, Selhan GÜrkan, Serpİl Mungan Durankaya, Tahsİn OĞuz BaŞokÇu, GÜnay Kirkim,

BACKGROUND/AIM:The study aimed to investigate the effect of training in hearing aid users to benefit from induction loop systems. MATERIALS AND METHODS:A five-question scale was developed to evaluate whether individuals using hearing aids could use the induction loop system effectively and validity-reliability studies were performed with 264 individuals using hearing ... Read more >>

Turk J Med Sci (Turkish journal of medical sciences)
[2020, :]

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The necessity is treating asymptomatic bacteriuria with antibiotics in the perioperative period of joint arthroplasty or not: a meta-analysis.

Sayed Abdulla Jami, Shi Jian Dang, Zhanwen Zhou, Liu Chang Hao,

Background Oral antibiotics are used to treat asymptomatic bacteriuria during the perioperative period of joint replacement usually. However, there is no unified conclusion on whether or not asymptomatic bacteriuria causes infection around joint prostheses, and the efficacy of antibiotics is unknown. Methods We systematically searched PubMed, CNKI, Ovid, Cochrane Library, ... Read more >>

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[2020, :]

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Do initial hematologic indices predict the severity of COVID-19 patients?

Alİ Asan, Yasemİn ÜstÜndaĞ, Nİzameddİn Koca, Abdullah ŞİmŞek, Halİl Erkan Sayan, HÜlya Parildar, Burcu Dalyan Cİlo, KaĞan Huysal,

BACKGROUND/AIM:In this study, we aimed to evaluate the initial hematological findings analyzed on admission in confirmed COVID-19 patients who were transferred to the intensive care unit (ICU), to predict possible hematological indices. MATERIALS AND METHODS:Initial neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), monocyte to lymphocyte ratio (MLR), ... Read more >>

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[2020, :]

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A practical method of drug provocation testing to prove tolerance to alternative drugs in drug hypersensitivity.

Ebru ÇelebİoĞlu, Özge ÖztÜrk AktaŞ, GÜl Karakaya, Alİ Fuat Kalyoncu,

BACKGROUND/AIM:Drug provocation test (DPT) is the gold standard method that is performed at the end of a stepwise approach in drug allergy work up. DPT is administered with a single drug on a test day. Testing more than one drug in a day would be a feasible option, time and ... Read more >>

Turk J Med Sci (Turkish journal of medical sciences)
[2020, :]

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COVID-19 transmission sources, management, and scientific research in Turkey.

Fatİh Kahraman, Adem Özkara,

Letter to the Editor. ... Read more >>

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[2020, :]

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The effect of measurement area size on the reliability of myocardial iron load measurement in cardiac magnetic resonance imaging examinations of thalassemia patients.

İbrahİm Önder YenİÇerİ, Fatİh Mehmet Azik, Funda DİnÇ Elİbol,

BACKGROUND/AIM:The aim of this study was to evaluate the intraobserver and interobserver reliability of cardiac T2* MRI measurements in the different region of interest (ROI) sizes. MATERIALS AND METHODS:Cardiac T2* MRIs of 24 thalassemia major patients were evaluated. Two different (ROI) sizes were used for measurement. In the first measurement, ... Read more >>

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[2020, :]

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The Effect of Ankaferd Blood Stopper on Liver Damage in Experimental Obstructive Jaundice.

Koray KoŞmaz, Abdullah Durhan, Marlen SÜleyman, Yilmaz Ünal, Mustafa Taner Bostanci, TuĞba YİĞİt Haskaraca, Can Ersak, Mehmet ŞeneŞ, İlknur Alkan KuŞabbİ, Eylem Pinar Eser, Sema HÜcÜmenoĞlu,

BACKGROUND:To evaluate the potential protective effects of Ankaferd blood stopper(ABS) in experimental Obstructive jaundice (OJ) model. MATERIALS AND METHODS:The study included 26 female rats which were divided into 3 groups. The sham group, consisting 10 rats, (Group 1) only received solely laparotomy. In the control group, consisting 8 rats, (Group ... Read more >>

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[2020, :]

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The assessment of the serum levels of TWEAK and prostaglandin F2? in COVID - 19.

Demet YalÇin Kehrİbar, Mustafa CİhangİroĞlu, Emİne Sehmen, Bahattİn Avci, Mustafa Çapraz, Maruf Boran, Caner GÜnaydin, Metİn Özgen,

BACKGROUND/AIM:It is claimed that aberrant immune response has a more important role than the cytopathic effect of the virus in the morbidity and mortality of the coronavirus disease 2019 (COVID - 19). We aimed to investigate the possible roles of tumor necrosis factor-like weak inducer of apoptosis (TWEAK) / Fn14 ... Read more >>

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[2020, :]

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MUC1 and MUC5AC implication in Tunisian colorectal cancer patients.

Meriam Hazgui, Marwa Weslati, Rahma Boughriba, Donia Ounissi, Dhouha Bacha, Saadia Bouraoui,

BACKGROUND/AIM:Mucins such as MUC1 and MUC5AC are known for their protective and moisturizing role of the intestinal epithelium. Their expression is tightly controlled given their essential role in the normal tissue homeostasis, whereas their deregulation leads to chronic inflammation and even cancer. This study aims to assess the expression profiles ... Read more >>

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[2020, :]

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What is predictive value of preoperative CA 125 level on survival rate of type-1 endometrial cancer?

Şafak Yilmaz Baran, SongÜl AlemdaroĞlu, GÜlŞen DoĞan DurdaĞ, Seda YÜksel ŞİmŞek, Fİlİz Bolat, Fatİh KÖse, HÜsnÜ Çelİk,

BACKGROUND/AIM:The purpose of the presented study is to investigate the utility of preoperative serum cancer antigen 125 (CA 125) levels in type-1 endometrial carcinoma as a marker for determining poor prognostic factors and survival. MATERIAL AND METHODS:All patients with endometrial cancer treated between 2012 and 2020 were retrospectively reviewed and ... Read more >>

Turk J Med Sci (Turkish journal of medical sciences)
[2020, :]

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Retrospective Evaluation of 377 Patients with Penetrating Foreign Body Injuries: A University Hospital Experience (A present case of missed sponge foreign body injury).

Anil Ozturk, Omar Aljasim, Gamze ŞanlidaĞ, Meltem TaŞbakan,

BACKGROUND/AIM:This study aimed to analyze retrospectively patients with FB injuries in our hospital and to present a patient with missed penetrating sponge FB injury. MATERIALS AND METHODS:This study covered 12 years (2008-2020) and reviewed all patients with FB injury who were admitted to the emergency department of our hospital. Besides ... Read more >>

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[2020, :]

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Validation of the NoSAS score for screening sleep disordered breathing; A sleep clinic-based study in Turkey.

Burcu Oktay Arslan, Zeynep Zeren UÇar, ÖzgÜr Batum, Mehmet Nurullah Orman,

BACKGROUND/AIM:NoSAS score is a new tool for identification of high-risk patients for sleep disordered breathing (SDB). The aim of this study was to validate the NoSAS score in sleep clinical population in Turkey and, compare its performance with Epworth Sleepiness Scale (ESS), STOP-Bang and Berlin questionnaires for high-risk SDB. MATERIALS ... Read more >>

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[2020, :]

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Efficacy, Retention And Safety Of Tofacitinib In Real-Life: Hur-Bio Monocentric Experience.

Emre Bİlgİn, Furkan Ceylan, Emİne Duran, Bayram FarİsoĞullari, ErtuĞrul ÇaĞri BÖlek, GÖzde KÜbra Yardimci, Levent KiliÇ, Alİ AkdoĞan, Ömer KaradaĞ, Şazİye Şule ApraŞ Bİlgen, Sedat Kİraz, Alİ İhsan Ertenlİ, Umut Kalyoncu,

OBJECTIVE:To assess the real-life efficacy, retention rate and safety data of tofacitinib in rheumatoid arthritis (RA) patients. METHOD:We analyzed all patients registered in the HURBIO database who received at least 1 dose of tofacitinib. Patients who received at least one dose included in retention analysis, with at least 1 control ... Read more >>

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[2020, :]

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Subcapsular local anesthesia approach in percutaneous liver biopsy: Less pain, more Comfort.

ÖzgÜr Çakir, Can Aksu,

BACKGROUND/AIM:To compare the subjective level of pain in patients who underwent an ultrasound-guided percutaneous liver biopsy (PLB) after either pericapsular anesthesia (PA) or subcapsular anesthesia (SA), based on the Numeric Rating Scale (NRS). MATERIALS AND METHODS:A total of 323 patients, mean age 51, range 21-82 years; 160 (49.5%) male, referred ... Read more >>

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[2020, :]

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Breast cancer early detection: Role of circulating plasma miRNA-21 expression as a potential screening biomarker.

Muhammad Noor Diansyah, Ami Ashariati Prayogo, Made Putra Sedana, Merlyna Savitri, Pradana Zaky Romadhon, Putu Niken Ayu Amrita, Andi Yasmin Wijaya, Winona May Hendrata, Ugroseno Yudho Bintoro,

AIM:To explore the circulating plasma miRNA-21 potential as early detection biomarker by comparing early-stage breast cancer (BG) and healthy control (HG) in Indonesian population. MATERIALS AND METHODS:The enlisted patients were twenty-six adult female early-stage breast cancer patients (stage 1A, 1B, 2A and 2B) of Airlangga University Hospital from August until ... Read more >>

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[2020, :]

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Frailty is associated with poor sleep quality in the oldest old.

ÇaĞatay ÇavuŞoĞlu, Olgun Denİz, Rana Tuna DoĞrul, SÜheyla ÇÖtelİ, Alİ ÖncÜl, Muhammet Cemal KizilarslanoĞlu, Berna GÖker,

BACKGROUND/AIM:Sleep disorders and frailty increase with advancing age, along with physical disabilities, cognitive dysfunction, mood disorders, and social vulnerability. Thus, the study objective was to evaluate the relationship between frailty and sleep quality in the oldest old patients. MATERIALS AND METHODS:One hundred patients aged ? 80 years were included and ... Read more >>

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[2020, :]

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Characteristics and Mortality Determinants of COVID-19 Patients Undergoing Haemodialysis.

SavaŞ Sİpahİ, Hamad Dheİr, Aysel ToÇoĞlu, Melİke BektaŞ, Seyyİd Bİlal AÇikgÖz, Ahmed Cİhad GenÇ, Fuldem Mutlu, Mehmet KÖroĞlu, Alİ Fuat Erdem, OĞuz Karabay,

BACKGROUND/AIM:COVID-19 infection which started in Wuhan City, China in December 2019 turned into a pandemic in a very short time, affecting mainly the elderly and those with serious chronic illnesses. COVID-19 infection has been observed with a high mortality rate especially in patients undergoing maintenance haemodialysis. MATERIALS AND METHODS:Forty-two patients ... Read more >>

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[2020, :]

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Emergency department extracorporeal membrane oxygenation may also include non-cardiac arrest patients.

Yunus Emre ÖzlÜer, MÜcahİt Avcİl, Duygu Ege, Kezban Şeker YaŞar,

BACKGROUND/AIM:The primary purpose of this study is to report the experience on the extracorporeal membrane oxygenation (ECMO) process for patients in the critical care unit of an Emergency Department of a tertiary hospital in Turkey, from cannulation to decannulation, including follow-up procedures. MATERIALS AND METHODS:This retrospective, observational study included eight ... Read more >>

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[2020, :]

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Vertebral compression fractures: Still an unpredictable aspect of osteoporosis.

Fatma YeŞİm Kutsal, Gİzem Olgu Ergİn Erganİ,

Vertebral compression fracture is a hallmark of osteoporosis and by far and away the most prevalent fragility fracture. It is well proven that, patients who develop a vertebral compression fracture are at substantial risk for additional fractures. Diagnosis is based on adequate clinical evaluation, imaging and laboratory tests. Imaging of ... Read more >>

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[2020, :]

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Physiological and pharmacological roles of melatonin in the pathophysiological components of cellular injury after ischemic stroke.

ErtuĞrul KiliÇ, Berrak ÇaĞlayan, Mustafa Caglar Beker,

Apart from its metabolic or physiological functions, melatonin has a potent cytoprotective activity in the physiological and pathological conditions. It is synthetized by the pineal gland and released into the blood circulation but particularly cerebrospinal fluid in a circadian manner. It can also easily diffuse through cellular membranes due its ... Read more >>

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[2020, :]

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The prognostic value of a proliferation-inducing ligand (APRIL) serum levels in treatment-naive patients with chronic lymphocytic leukemia.

Sİnem Nİhal EsatoĞlu, Dİlek Keskİn, Ahmet Emre EŞkazan, TuĞrul Elverdİ, AyŞe SalİhoĞlu, Muhlİs Cem Ar, Şenİz ÖngÖren, Zafer BaŞlar, Yildiz Aydin, Hafİze Uzun, Teoman Soysal,

BACKGROUND/AIM:A proliferation inducing ligand (APRIL) has been investigated as a prognostic marker in chronic lymphocytic leukemia (CLL) patients. However, there is no cut-off level for serum APRIL (sAPRIL) levels that predict time to treatment in CLL patients. MATERIALS AND METHODS:Between May and December 2012, consecutive 94 CLL patients and 25 ... Read more >>

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