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Advancing mental health equality: a mapping review of interventions, economic evaluations and barriers and facilitators.

Laura-Louise Arundell, Helen Greenwood, Helen Baldwin, Eleanor Kotas, Shubulade Smith, Kasia Trojanowska, Chris Cooper,

BACKGROUND:This work aimed to identify studies of interventions seeking to address mental health inequalities, studies assessing the economic impact of such interventions and factors which act as barriers and those that can facilitate interventions to address inequalities in mental health care. METHODS:A systematic mapping method was chosen. Studies were included ... Read more >>

Syst Rev (Systematic reviews)
[2020, 9(1):115]

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Locating unregistered and unreported data for use in a social science systematic review and meta-analysis.

Joshua R Polanin, Dorothy L Espelage, Jennifer K Grotpeter, Alberto Valido, Katherine M Ingram, Cagil Torgal, America El Sheikh, Luz E Robinson,

Meta-analysts rely on the availability of data from previously conducted studies. That is, they rely on primary study authors to register their outcome data, either in a study's text or on publicly available websites, and report the results of their work, either again in a study's text or on publicly ... Read more >>

Syst Rev (Systematic reviews)
[2020, 9(1):116]

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Does suboptimal household flooring increase the risk of diarrhoea and intestinal parasite infection in low and middle income endemic settings? A systematic review and meta-analysis protocol.

Benn Sartorius, Hugo Legge, Rachel Pullan,

BACKGROUND:Water, sanitation, and hygiene interventions often fail to show long-term impact on diarrhoeal and/or intestinal parasite risk in many low- and middle-income countries. Less attention has been paid to wider contextual factors that may contribute to high levels of contamination in the domestic environment such as household flooring. The purpose ... Read more >>

Syst Rev (Systematic reviews)
[2020, 9(1):113]

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Improving the usefulness of evidence concerning the effectiveness of implementation strategies for knowledge products in primary healthcare: protocol for a series of systematic reviews.

Hervé Tchala Vignon Zomahoun, José Massougbodji, André Bussières, Aliki Thomas, Dahlia Kairy, Claude Bernard Uwizeye, Nathalie Rheault, Ali Ben Charif, Ella Diendéré, Léa Langlois, Sébastien Tchoubi, Serigne Abib Gaye, France Légaré,

BACKGROUND:The literature on the implementation of knowledge products is extensive. However, this literature is still difficult to interpret for policymakers and other stakeholders when faced with choosing implementation strategies likely to bring about successful change in their health systems. This work has the particularity to examine the scope of this ... Read more >>

Syst Rev (Systematic reviews)
[2020, 9(1):112]

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Vitamin B-Can it prevent cognitive decline? A systematic review and meta-analysis.

Annika Behrens, Elmar Graessel, Anna Pendergrass, Carolin Donath,

BACKGROUND:Development of cognitive decline represents substantial issues in today's society, steadily gaining importance with increasing life expectancy. One potential approach to preventing cognitive decline is to lower homocysteine by administering vitamin B. In this systematic review and meta-analysis, we address this topic and investigate whether oral supplementation of vitamin B ... Read more >>

Syst Rev (Systematic reviews)
[2020, 9(1):111]

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Physical activity promotion for multimorbid patients in primary care settings: a protocol for a systematic review evaluating health benefits and harms.

Simone Schweda, Inga Krauss,

BACKGROUND:To date multimorbidity has not received much attention in health policies, even though multiple chronic diseases put high demands on the health care system in industrial nations. Enormous costs of care and a physically, mentally, and socially reduced quality of life are common consequences of multimorbidity. Physical activity (PA) has ... Read more >>

Syst Rev (Systematic reviews)
[2020, 9(1):110]

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Association between pesticide exposure and paraoxonase-1 (PON1) polymorphisms, and neurobehavioural outcomes in children: a systematic review.

Nkosinathi Banhela, Pragalathan Naidoo, Saloshni Naidoo,

Environmental factors such as pollution, pesticide exposure and socio-demographic location have been implicated as a pressure capable of altering genetic make-up. Altered genetic sequence of genes encoding enzymes may result in single nucleotide polymorphism (SNP). Of peculiar interest is the genetic variance on the paraoxonase-1 gene induced by pre- and ... Read more >>

Syst Rev (Systematic reviews)
[2020, 9(1):109]

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Physiologic perfusion monitoring methods during endovascular revascularization for atherosclerotic peripheral arterial disease: protocol for a systematic review.

Mark Rockley, Prasad Jetty, George Wells,

BACKGROUND:Endovascular therapy is a fundamental treatment for peripheral arterial disease. However, the success rate of endovascular therapy remains poor, as a third of patients with critical limb ischemia ultimately require a major amputation for gangrene despite endovascular treatment. This failure rate has prompted investigation into methods of determining physiologic procedural ... Read more >>

Syst Rev (Systematic reviews)
[2020, 9(1):107]

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Systematic review of patient-oriented interventions to reduce unnecessary use of antibiotics for upper respiratory tract infections.

Sameh Mortazhejri, Patrick Jiho Hong, Ashley M Yu, Brian Younho Hong, Dawn Stacey, R Sacha Bhatia, Jeremy M Grimshaw,

BACKGROUND:Antibiotics are prescribed frequently for upper respiratory tract infections (URTIs) even though most URTIs do not require antibiotics. This over-prescription contributes to antibiotic resistance which is a major health problem globally. As physicians' prescribing behaviour is influenced by patients' expectations, there may be some opportunities to reduce antibiotic prescribing using ... Read more >>

Syst Rev (Systematic reviews)
[2020, 9(1):106]

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Increased circulating vascular endothelial growth factor in acute myeloid leukemia patients: a systematic review and meta-analysis.

Mingzhu Song, Huiping Wang, Qianling Ye,

BACKGROUND:Vascular endothelial growth factor (VEGF) is one of the angiogenesis regulators, which plays an important role in tumor angiogenesis and tumor progression. Current studies have found that VEGF plays an important role in hematologic diseases including acute myeloid leukemia (AML). However, the circulating levels of VEGF in AML were still ... Read more >>

Syst Rev (Systematic reviews)
[2020, 9(1):103]

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Determining optimal strategies for primary prevention of cardiovascular disease: systematic review, cost-effectiveness review and network meta-analysis protocol.

Olalekan A Uthman, Lena Al-Khudairy, Chidozie U Nduka, Rachel Court, Hema Mistry, G J Melendez-Torres, Sian Taylor-Phillips, Aileen Clarke,

BACKGROUND:Despite recent improvements in the burden of cardiovascular disease (CVD) in the UK, deaths from CVD are relatively high compared with other high-income countries. An estimated 7 million people in the UK are living with CVD, and the healthcare cost is approximately £11 billion annually. In more than 90% of ... Read more >>

Syst Rev (Systematic reviews)
[2020, 9(1):105]

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Novel wearable and contactless monitoring devices to identify deteriorating patients in the clinical setting: a systematic review protocol.

Peter Y Chan, John McNeil, Tam Nguyen, Nicholas Ryan, Ingrid Hopper,

BACKGROUND:With technological advances, there has been increasing interest in developing contactless and/or non-invasive wearable technologies that continuously monitor vital signs in the clinical setting, and in particular in the deteriorating patient. These devices as of yet have not been well validated in the clinical setting in the clinical ranges observed ... Read more >>

Syst Rev (Systematic reviews)
[2020, 9(1):104]

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Associations of loneliness and social isolation with cardiovascular and metabolic health: a systematic review and meta-analysis protocol.

Adriano Winterton, Linn Rødevand, Lars T Westlye, Nils Eiel Steen, Ole A Andreassen, Daniel S Quintana,

BACKGROUND:A growing number of studies suggest that social isolation and loneliness are associated with premature mortality and are more prevalent among people with mental illness than in the general population, outlining many potential paths to disease still to be elucidated. The purpose of this meta-analysis is to examine the relationship ... Read more >>

Syst Rev (Systematic reviews)
[2020, 9(1):102]

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Interventions for treatment of COVID-19: a protocol for a living systematic review with network meta-analysis including individual patient data (The LIVING Project).

Sophie Juul, Niklas Nielsen, Peter Bentzer, Areti Angeliki Veroniki, Lehana Thabane, Adam Linder, Sarah Klingenberg, Christian Gluud, Janus Christian Jakobsen,

BACKGROUND:COVID-19 is a rapidly spreading virus infection that has quickly caused extensive burden to individual, families, countries, and the globe. No intervention has yet been proven effective for the treatment of COVID-19. Some randomized clinical trials assessing the effects of different drugs have been published, and more are currently underway. ... Read more >>

Syst Rev (Systematic reviews)
[2020, 9(1):108]

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A focus on cross-purpose tools, automated recognition of study design in multiple disciplines, and evaluation of automation tools: a summary of significant discussions at the fourth meeting of the International Collaboration for Automation of Systematic Reviews (ICASR).

Annette M O'Connor, Paul Glasziou, Michele Taylor, James Thomas, René Spijker, Mary S Wolfe,

The fourth meeting of the International Collaboration for Automation of Systematic Reviews (ICASR) was held 5-6 November 2019 in The Hague, the Netherlands. ICASR is an interdisciplinary group whose goal is to maximize the use of technology for conducting rapid, accurate, and efficient systematic reviews of scientific evidence. The group ... Read more >>

Syst Rev (Systematic reviews)
[2020, 9(1):100]

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The prevalence of type 2 diabetes in people with psychiatric disorders: an umbrella review protocol.

N Lindekilde, S Scheuer, F Rutters, J E Henriksen, K H Rubin, M Lasgaard, G S Andersen, F Pouwer,

BACKGROUND:Many epidemiological studies have investigated the prevalence of type 2 diabetes in individuals with a psychiatric disorder. In an umbrella review, we aim to systematically summarize existing systematic reviews examining the prevalence of type 2 diabetes in people with a psychiatric disorder. When information is available in the identified systematic ... Read more >>

Syst Rev (Systematic reviews)
[2020, 9(1):101]

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Prevalence of hypertension and its risk factors among cotton textile workers in low- and middle-income countries: a protocol for a systematic review.

Naureen Akber Ali, Anam Shahil Feroz,

BACKGROUND:Cotton workers are exposed to various hazards in the textile industry that might result in different ailments including hypertension (HTN). However, few attempts have been made to systematically review the prevalence of hypertension and its risk factor among cotton textile workers in low-and middle-income countries (LMICs). The objective of this ... Read more >>

Syst Rev (Systematic reviews)
[2020, 9(1):99]

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Safety and efficiency of gasless laparoscopy: a systematic review protocol.

Haitham Shoman, Simone Sandler, Alexander Peters, Ameer Farooq, Magdalen Gruendl, Shauna Trinh, James Little, Alex Woods, William Bolton, Abubakar Abioye, David Ljungman,

BACKGROUND:Gasless laparoscopy, developed in the early 1990s, was a means to minimize the clinical and financial challenges of pneumoperitoneum and general anaesthesia. It has been used in a variety of procedures such as in general surgery and gynecology procedures including diagnostic laparoscopy. There has been increasing evidence of the utility ... Read more >>

Syst Rev (Systematic reviews)
[2020, 9(1):98]

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A scoping review of network meta-analyses assessing the efficacy and safety of complementary and alternative medicine interventions.

Misty Pratt, Susan Wieland, Nadera Ahmadzai, Claire Butler, Dianna Wolfe, Kusala Pussagoda, Becky Skidmore, Argie Veroniki, Patricia Rios, Andrea C Tricco, Brian Hutton,

BACKGROUND:Network meta-analysis (NMA) has rapidly grown in use during the past decade for the comparison of healthcare interventions. While its general use in the comparison of conventional medicines has been studied previously, to our awareness, its use to assess complementary and alternative medicines (CAM) has not been studied. A scoping ... Read more >>

Syst Rev (Systematic reviews)
[2020, 9(1):97]

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Noninvasive oxygenation strategies in adult patients with acute respiratory failure: a protocol for a systematic review and network meta-analysis.

Bruno L Ferreyro, Federico Angriman, Laveena Munshi, Lorenzo Del Sorbo, Niall D Ferguson, Bram Rochwerg, Michelle J Ryu, Refik Saskin, Hannah Wunsch, Bruno R da Costa, Damon C Scales,

BACKGROUND:Acute hypoxemic respiratory failure is one of the leading causes of intensive care unit admission and is associated with high mortality. Noninvasive oxygenation strategies such as high-flow nasal cannula, standard oxygen therapy, and noninvasive ventilation (delivered by either face mask or helmet interface) are widely available interventions applied in these patients. ... Read more >>

Syst Rev (Systematic reviews)
[2020, 9(1):95]

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The role of exposure in the treatment of anxiety in children and adolescents: protocol of a systematic review and meta-analysis.

Kathrin Schopf, Cornelia Mohr, Michael W Lippert, Katharina Sommer, Andrea Hans Meyer, Silvia Schneider,

BACKGROUND:In children and adolescents, anxiety disorders (ADs) are among the most prevalent mental disorders. While there is a solid empirical foundation to support CBT as an evidence-based treatment for childhood ADs, the mechanisms underlying the efficacy of CBT are not well explored. Exposure is assumed to be vital to the ... Read more >>

Syst Rev (Systematic reviews)
[2020, 9(1):96]

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The influence of contextual factors on healthcare quality improvement initiatives: a realist review.

Emma Coles, Julie Anderson, Margaret Maxwell, Fiona M Harris, Nicola M Gray, Gill Milner, Stephen MacGillivray,

BACKGROUND:Recognising the influence of context and the context-sensitive nature of quality improvement (QI) interventions is crucial to implementing effective improvements and successfully replicating them in new settings, yet context is still poorly understood. To address this challenge, it is necessary to capture generalisable knowledge, first to understand which aspects of ... Read more >>

Syst Rev (Systematic reviews)
[2020, 9(1):94]

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HIV-1 integrase resistance associated mutations and the use of dolutegravir in Sub-Saharan Africa: a systematic review and meta-analysis protocol.

Ezechiel Ngoufack Jagni Semengue, Maria Mercedes Santoro, Valantine Ngum Ndze, Beatrice Dambaya, Desiré Takou, Georges Teto, Alex Durand Nka, Lavinia Fabeni, Alison Wiyeh, Francesca Ceccherini-Silberstein, Vittorio Colizzi, Carlo-Federico Perno, Joseph Fokam,

BACKGROUND:Sub-Saharan Africa carries the greatest burden of HIV-infection with increasing drug resistance burden, which requires improved patient management and monitoring. Current WHO recommendations suggest transitioning to dolutegravir-based (adults) or raltegravir-based-regimens (neonates) for initial antiretroviral therapy (ART) and as a suitable alternative in cases of multi-resistance in resource-limited settings. This review ... Read more >>

Syst Rev (Systematic reviews)
[2020, 9(1):93]

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A systematic review and taxonomy of tools for evaluating evidence-based medicine teaching in medical education.

Bharathy Kumaravel, Jasmine Heath Hearn, Leila Jahangiri, Rachel Pollard, Claire J Stocker, David Nunan,

BACKGROUND:The importance of teaching the skills and practice of evidence-based medicine (EBM) for medical professionals has steadily grown in recent years. Alongside this growth is a need to evaluate the effectiveness of EBM curriculum as assessed by competency in the five 'A's': asking, acquiring, appraising, applying and assessing (impact and ... Read more >>

Syst Rev (Systematic reviews)
[2020, 9(1):91]

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School-going transgender youths' experiences at health care facilities: a systematic scoping review protocol.

Delarise M Mulqueeny, Senzelokuhle M Nkabini, Tivani P Mashamba-Thompson,

BACKGROUND:Globally, miniscule improvements have been implemented regarding equality, inclusion, access, and protection of people with diverse gender identities whilst accessing health care facilities of which transgender youth form part. Literature has highlighted that the care transgender youth receive at health care facilities can result in positive or negative outcomes. School-going ... Read more >>

Syst Rev (Systematic reviews)
[2020, 9(1):90]

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