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New fossil discoveries illustrate the diversity of past terrestrial ecosystems in New Caledonia.

Romain Garrouste, Jérôme Munzinger, Andrew Leslie, Jessica Fisher, Nicolas Folcher, Emma Locatelli, Wyndy Foy, Thibault Chaillon, David J Cantrill, Pierre Maurizot, Dominique Cluzel, Porter P Lowry, Peter Crane, Jean-Jacques Bahain, Pierre Voinchet, Hervé Jourdan, Philippe Grandcolas, André Nel,

New Caledonia was, until recently, considered an old continental island harbouring a rich biota with outstanding Gondwanan relicts. However, deep marine sedimentation and tectonic evidence suggest complete submergence of the island during the latest Cretaceous to the Paleocene. Molecular phylogenies provide evidence for some deeply-diverging clades that may predate the ... Read more >>

Sci Rep (Scientific reports)
[2021, 11(1):18388]

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Author Correction: New insights into structure and function of bis-phosphinic acid derivatives and implications for CFTR modulation.

Sara Bitam, Ahmad Elbahnsi, Geordie Creste, Iwona Pranke, Benoit Chevalier, Farouk Berhal, Brice Hoffmann, Nathalie Servel, Nesrine Baatalah, Danielle Tondelier, Aurelie Hatton, Christelle Moquereau, Mélanie Faria Da Cunha, Alexandra Pastor, Agathe Lepissier, Alexandre Hinzpeter, Jean-Paul Mornon, Guillaume Prestat, Aleksander Edelman, Isabelle Callebaut, Christine Gravier-Pelletier, Isabelle Sermet-Gaudelus,

Sci Rep (Scientific reports)
[2021, 11(1):18709]

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Combined effect of nitrogen-doped functional groups and porosity of porous carbons on electrochemical performance of supercapacitors.

Anna Ilnicka, Malgorzata Skorupska, Mariusz Szkoda, Zuzanna Zarach, Piotr Kamedulski, Wojciech Zielinski, Jerzy P Lukaszewicz,

In this work, nitrogen-doped porous carbons obtained from chitosan, gelatine, and green algae were investigated in their role as supercapacitor electrodes. The effects of three factors on electrochemical performance have been studied-of the specific surface area, functional groups, and a porous structure. Varying nitrogen contents (from 5.46 to 10.08 wt.%) and ... Read more >>

Sci Rep (Scientific reports)
[2021, 11(1):18387]

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Scaling theory of rubber sliding friction.

Reinhard Hentschke, Jan Plagge,

Current theoretical descriptions of rubber or elastomer friction are complex-usually due to extensive mathematical detail describing the topography of the solid surface. In addition, the viscoelastic properties of the elastomer material itself, in particular if the rubber is highly filled, further increase the complexity. On the other hand, experimental coefficients ... Read more >>

Sci Rep (Scientific reports)
[2021, 11(1):18306]

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Publisher Correction: Superradiance of bacteriochlorophyll c aggregates in chlorosomes of green photosynthetic bacteria.

Tomáš Malina, Rob Koehorst, David Bína, Jakub Pšenčík, Herbert van Amerongen,

Sci Rep (Scientific reports)
[2021, 11(1):18739]

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Author Correction: Introduction and reproducibility of an updated practical grading system for lumbar foraminal stenosis based on high-resolution MR imaging.

Elisabeth Sartoretti, Michael Wyss, Alex Alfieri, Christoph A Binkert, Cyril Erne, Sabine Sartoretti-Schefer, Thomas Sartoretti,

Sci Rep (Scientific reports)
[2021, 11(1):18732]

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Rapid MRSA detection via tandem mass spectrometry of the intact 80 kDa PBP2a resistance protein.

Jason R Neil, Arvind Verma, Scott R Kronewitter, William M McGee, Christopher Mullen, Marjaana Viirtola, Annika Kotovuori, Herdis Friedrich, Johan Finell, Joni Rannisto, John E P Syka, James L Stephenson,

Treatment of antibiotic-resistant infections is dependent on the detection of specific bacterial genes or proteins in clinical assays. Identification of methicillin-resistant Staphylococcus aureus (MRSA) is often accomplished through the detection of penicillin-binding protein 2a (PBP2a). With greater dependence on mass spectrometry (MS)-based bacterial identification, complementary efforts to detect resistance have ... Read more >>

Sci Rep (Scientific reports)
[2021, 11(1):18309]

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Author Correction: Peripheral vasoreactivity in acute ischemic stroke with hemiplegia.

Su Jeong Wang, Chan-Hyuk Lee, Hyun Goo Kang, Ko Woon Kim, Minjoo Kim, Hwan-Jeong Jeong, Byoung-Soo Shin,

Sci Rep (Scientific reports)
[2021, 11(1):18710]

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The radiographic relationship between the cortical overlap view (COV) and the tip of the greater trochanter.

Bjorn-Christian Link, Nicole M van Veelen, Katja Boernert, Piyabuth Kittithamvongs, Frank J P Beeres, Hans H de Boer, Filippo Migliorini, Sven Nebelung, Matthias Knobe, Steffen Ruchholtz, Reto Babst, Chittawee Jiamton,

For proximal femoral nailing, choosing the proper entry point with the aid of C-arm imaging is crucial. Therefore, obtaining accurate radiological views that facilitate sound identification of the tip of the greater trochanter (GT) is of utmost importance. The aim of this study was to define a radiological view characterised ... Read more >>

Sci Rep (Scientific reports)
[2021, 11(1):18404]

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Hybrid derivative of cathelicidin and human beta defensin-2 against Gram-positive bacteria: A novel approach for the treatment of bacterial keratitis.

Darren Shu Jeng Ting, Eunice Tze Leng Goh, Venkatesh Mayandi, Joanna M F Busoy, Thet Tun Aung, Mercy Halleluyah Periayah, Mario Nubile, Leonardo Mastropasqua, Dalia G Said, Hla M Htoon, Veluchamy Amutha Barathi, Roger W Beuerman, Rajamani Lakshminarayanan, Imran Mohammed, Harminder S Dua,

Bacterial keratitis (BK) is a major cause of corneal blindness globally. This study aimed to develop a novel class of antimicrobial therapy, based on human-derived hybrid host defense peptides (HyHDPs), for treating BK. HyHDPs were rationally designed through combination of functional amino acids in parent HDPs, including LL-37 and human ... Read more >>

Sci Rep (Scientific reports)
[2021, 11(1):18304]

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Asialoglycoprotein receptor targeted optical and magnetic resonance imaging and therapy of liver fibrosis using pullulan stabilized multi-functional iron oxide nanoprobe.

Ariya Saraswathy, Shaiju S Nazeer, Nirmala Nimi, Hema Santhakumar, Parvathy Radhakrishnapillai Suma, Kunnumpurathu Jibin, Marina Victor, Francis Boniface Fernandez, Sabareeswaran Arumugam, Sachin J Shenoy, P R Harikrishna Varma, Ramapurath S Jayasree,

Early diagnosis and therapy of liver fibrosis is of utmost importance, especially considering the increased incidence of alcoholic and non-alcoholic liver syndromes. In this work, a systematic study is reported to develop a dual function and biocompatible nanoprobe for liver specific diagnostic and therapeutic applications. A polysaccharide polymer, pullulan stabilized ... Read more >>

Sci Rep (Scientific reports)
[2021, 11(1):18324]

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Adipokinetic hormone (AKH), energy budget and their effect on feeding and gustatory processes of foraging honey bees.

Gabriela de Brito Sanchez, Anna Expósito Muñoz, Li Chen, Weifone Huang, Songkun Su, Martin Giurfa,

The adipokinetic hormone (AKH) of insects is considered an equivalent of the mammalian hormone glucagon as it induces fast mobilization of carbohydrates and lipids from the fat body upon starvation. Yet, in foraging honey bees, which lack fat body storage for carbohydrates, it was suggested that AKH may have lost ... Read more >>

Sci Rep (Scientific reports)
[2021, 11(1):18311]

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Decision making on vestibular schwannoma treatment: predictions based on machine-learning analysis.

Oliver Profant, Zbyněk Bureš, Zuzana Balogová, Jan Betka, Zdeněk Fík, Martin Chovanec, Jan Voráček,

Decision making on the treatment of vestibular schwannoma (VS) is mainly based on the symptoms, tumor size, patient's preference, and experience of the medical team. Here we provide objective tools to support the decision process by answering two questions: can a single checkup predict the need of active treatment?, and ... Read more >>

Sci Rep (Scientific reports)
[2021, 11(1):18376]

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Research on routing and scheduling algorithms for the simultaneous transmission of diverse data streaming services on the industrial internet.

Yan Song, Chenyang Guo, Panfeng Xu, Lina Li, Rui Zhang,

OPC UA PubSub Over TSN is the core of the Industrial Internet and guarantees flexible interaction features for multiple parties in real-time for industrial communication. To achieve the transmission of time-triggered traffic in PubSub NetworkMessage, routing and scheduling data need to be analyzed. Traditional routing and scheduling methods have disadvantages ... Read more >>

Sci Rep (Scientific reports)
[2021, 11(1):18351]

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Influence of electrical part of traction transmission on dynamic characteristics of railway vehicles based on electromechanical coupling model.

Xun Wang, Tiefeng Peng, Pingbo Wu, Litong Cui,

With the continuous development of rail transit industry and the acceleration of train speed, higher requirements are established for the operation quality of high-speed trains and the reliability of transmission system. In the process of train running, speed fluctuation and vibrations from various parts of the driving devices are common, ... Read more >>

Sci Rep (Scientific reports)
[2021, 11(1):18409]

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Gestalts at threshold could reveal Gestalts as predictions.

Thiago Leiros Costa, Johan Wagemans,

We review and revisit the predictive processing inspired "Gestalts as predictions" hypothesis. The study of Gestalt phenomena at and below threshold can help clarify the role of higher-order object selective areas and feedback connections in mid-level vision. In two psychophysical experiments assessing manipulations of contrast and configurality we showed that: ... Read more >>

Sci Rep (Scientific reports)
[2021, 11(1):18308]

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A MATLAB-based program for three-dimensional quantitative analysis of micronuclei reveals that neuroinflammation induces micronuclei formation in the brain.

Sarasa Yano, Kaito Akiyama, Rio Tsuchiya, Hikari Kubotani, Tomoki Chiba, Takeshi Nagata, Fuminori Tsuruta,

The micronucleus is known to be a biomarker for genomic instability, which is a hallmark of tumors and aging. Normally, micronuclei are produced by segregation errors and mechanical stresses arising from dividing or migrating cells, leading to activation of the innate immune response pathway. Although micronuclei often emerge in damaged ... Read more >>

Sci Rep (Scientific reports)
[2021, 11(1):18360]

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VCAM1-α4β1 integrin interaction mediates interstitial tissue reconstruction in 3-D re-aggregate culture of dissociated prepubertal mouse testicular cells.

Kazuko Abe, Shigeyuki Kon, Hiroki Kameyama, JiDong Zhang, Ken-Ichirou Morohashi, Kenji Shimamura, Shin-Ichi Abe,

Roles of interstitial tissue in morphogenesis of testicular structures remain less well understood. To analyze the roles of CD34<sup>+</sup> cells in the reconstruction of interstitial tissue containing Leydig cells (LCs), and testicular structures, we used 3D-reaggregate culture of dissociated testicular cells from prepubertal mouse. After a week of culture, adult ... Read more >>

Sci Rep (Scientific reports)
[2021, 11(1):18332]

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Standard hospital blanket warming cabinets can be utilized for complete moist heat SARS-CoV2 inactivation of contaminated N95 masks for re-use.

Anand Kumar, Samantha B Kasloff, Todd Cutts, Anders Leung, Naresh Sharma, Gloria Vazquez-Grande, Tracy Drew, Denis Laframboise, Olivero Orofino, Joe Tanelli, Jay Krishnan,

Shortages of personal protective equipment for use during the SARS-CoV-2 pandemic continue to be an issue among health-care workers globally. Extended and repeated use of N95 filtering facepiece respirators without adequate decontamination is of particular concern. Although several methods to decontaminate and re-use these masks have been proposed, logistic or ... Read more >>

Sci Rep (Scientific reports)
[2021, 11(1):18316]

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Patient characteristics, treatment patterns, and outcomes of Rickettsial diseases among a commercially insured population in the United States, 2005-2017.

Alison M Binder, Paige A Armstrong,

Rickettsial diseases (RDs) are transmitted to humans by ectoparasites, including ticks and fleas. Symptoms range from mild febrile illness, to severe disease or death. Doxycycline is the treatment of choice for patients of all ages; early treatment based on clinical diagnosis is critical to prevent severe outcomes. We conducted a ... Read more >>

Sci Rep (Scientific reports)
[2021, 11(1):18382]

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Underwater noise mitigation in the Santa Barbara Channel through incentive-based vessel speed reduction.

Vanessa M ZoBell, Kaitlin E Frasier, Jessica A Morten, Sean P Hastings, Lindsey E Peavey Reeves, Sean M Wiggins, John A Hildebrand,

Commercial shipping is the dominant source of low-frequency noise in the ocean. It has been shown that the noise radiated by an individual vessel depends upon the vessel's speed. This study quantified the reduction in source levels (SLs) and sound exposure levels (SELs) for ships participating in two variations of ... Read more >>

Sci Rep (Scientific reports)
[2021, 11(1):18391]

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Physicochemical, antioxidant properties of carotenoids and its optoelectronic and interaction studies with chlorophyll pigments.

Ruby Srivastava,

The physicochemical and antioxidant properties of seven carotenoids: antheraxanthin, β-carotene, neoxanthin, peridinin, violaxanthin, xanthrophyll and zeaxanthin were studied by theoretical means. Then the Optoelectronic properties and interaction of chlorophyll-carotenoid complexes are analysed by TDDFT and IGMPLOT. Global reactivity descriptors for carotenoids and chlorophyll (Chla, Chlb) are calculated via conceptual density ... Read more >>

Sci Rep (Scientific reports)
[2021, 11(1):18365]

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Localised labyrinthine patterns in ecosystems.

M G Clerc, S Echeverría-Alar, M Tlidi,

Self-organisation is a ubiquitous phenomenon in ecosystems. These systems can experience transitions from a uniform cover towards the formation of vegetation patterns as a result of symmetry-breaking instability. They can be either periodic or localised in space. Localised vegetation patterns consist of more or less circular spots or patches that ... Read more >>

Sci Rep (Scientific reports)
[2021, 11(1):18331]

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KCa channel blockers increase effectiveness of the EGF receptor TK inhibitor erlotinib in non-small cell lung cancer cells (A549).

Felix Glaser, Petra Hundehege, Etmar Bulk, Luca Matteo Todesca, Sandra Schimmelpfennig, Elke Nass, Thomas Budde, Sven G Meuth, Albrecht Schwab,

Non-small cell lung cancer (NSCLC) has a poor prognosis with a 5 year survival rate of only ~ 10%. Important driver mutations underlying NSCLC affect the epidermal growth factor receptor (EGFR) causing the constitutive activation of its tyrosine kinase domain. There are efficient EGFR tyrosine kinase inhibitors (TKIs), but patients develop inevitably a ... Read more >>

Sci Rep (Scientific reports)
[2021, 11(1):18330]

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Quantifying the contribution of individual variation in timing to delay-discounting.

Evgeniya Lukinova, Jeffrey C Erlich,

Delay-discounting studies in neuroscience, psychology, and economics have been mostly focused on concepts of self-control, reward evaluation, and discounting. Another important relationship to consider is the link between intertemporal choice and time perception. We presented 50 college students with timing tasks on the range of seconds to minutes and intertemporal-choice ... Read more >>

Sci Rep (Scientific reports)
[2021, 11(1):18354]

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