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Journal Perfusion

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Use of venous-venous extracorporeal membrane oxygenation in the treatment of postpartum pulmonary hypertension crisis.

Yongpo Jiang, Minjuan Lou, Xiaoqiong Chu, Dan Zheng, Minjie Cai, Weili Zhao, RongHai Lin, Sheng Zhang,

The incidence of heart disease in pregnancy ranges from 0.5% to 3.0% and is regarded as one of the top three causes of maternal death. The mortality rate of patients with pulmonary hypertension and Eisenmenger syndrome is as high as 16.7%-50%. Changes in haemodynamics during pregnancy and childbirth increase the ... Read more >>

Perfusion (Perfusion)
[2021, :2676591211043705]

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Sedation and analgesia requirements during venovenous extracorporeal membrane oxygenation in acute respiratory distress syndrome patients.

Xingshu Ren, Yuhang Ai, Lina Zhang, Chunguang Zhao, Li Li, Xinhua Ma,

<h4>Introduction</h4>The purpose of this study is to describe sedation and analgesia management, and identify the factors associated with increased demand for medication in acute respiratory distress syndrome (ARDS) patients receiving venovenous extracorporeal membrane oxygenation (VV-ECMO).<h4>Methods</h4>This retrospective, single-center study included consecutive adult ARDS patients who received VV-ECMO for at least 24 hours ... Read more >>

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[2021, :2676591211052160]

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Editorial controls and obligations.

Prakash P Punjabi,

Perfusion (Perfusion)
[2021, 36(8):775-776]

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Short-term effects of levosimendan use for venoarterial extracorporeal membrane oxygenation: A systematic review and meta-analysis.

Boyu Yang, Tong Zhao, Bingyan Guo, Yongjun Li,

<h4>Objective</h4>Levosimendan has been demonstrated to reduce the incidence of cardiogenic shock and facilitate weaning from cardiopulmonary bypass. However, the beneficial effects of levosimendan treatment on hospital outcomes in patients receiving venoarterial extracorporeal membrane oxygenation (VA-ECMO) are uncertain. We performed a systematic review and meta-analysis to evaluate the short-term effects of ... Read more >>

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[2021, :2676591211051860]

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Nucleated red blood cells as a biomarker for mortality in infants and neonates requiring veno-arterial extracorporeal membrane oxygenation for cardiac disease.

Kurt D Piggott, Casey Norlin, Cynthia Laviolette, Jason Turner, LaTasha Lewis, Amira Soliman, David Hebert, Tim Pettitt,

<h4>Introduction</h4>Nucleated red blood cells (NRBC) are rare in the peripheral circulation of healthy individuals and their presence have been associated with mortality in adults and very low birth weight newborns, however, its value as a biomarker for mortality in infants requiring veno-arterial (VA) extracorporeal membrane oxygenation (ECMO) has yet to ... Read more >>

Perfusion (Perfusion)
[2021, :2676591211050607]

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Blocking vicious cycle of cardiac dysfunction by external cardiopulmonary resuscitation is the key to rescue acute aluminium phosphide poisoning.

Yan Shen, Daishan Jiang, Ting Wang, Mengqiu Li, Yayun Wang, Jingjing Li, Haixia Yan, Mingjun Yuan, Yunlan Ji, Yanbo Shen, Dingshan Yuan, Zhongwei Huang,

Aluminium phosphide (ALP) and aluminium zinc phosphide (ZnP), the two main ingredients of fumigation drugs, are commonly used to kill insects or rodents in grain. When exposed to water, highly toxic phosphine gas is released and absorbed through the respiratory or digestive tract. Phosphine gas could non-selectively block cytochrome oxidase, ... Read more >>

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[2021, :2676591211046868]

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Lower limb amputation following venous cannulation for VA-ECMO: a case report.

Natasha Habr, Jamal J Hoballah, Jamil Borgi, Caroline Hamadi, Pierre Sfeir, Fady Haddad,

Lower limb amputation following arterial cannulation for VA-ECMO has been described in the literature. Limb ischemia however following venous cannulation is very rare and not quite understood. We present a case of limb ischemia following venous cannulation. A combination of venous congestion, compartment syndrome and subsequent arterial insufficiency is the ... Read more >>

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[2021, :2676591211050608]

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Predictors of acute kidney injury in patients after extracorporeal cardiopulmonary resuscitation.

Christopher Gaisendrees, Borko Ivanov, Stephen Gerfer, Anton Sabashnikov, Kaveh Eghbalzadeh, Georg Schlachtenberger, Soi Avgeridou, Christian Rustenbach, Julia Merkle, Christopher Adler, Elmar Kuhn, Navid Mader, Ferdinand Kuhn-Régnier, Ilija Djordjevic, Thorsten Wahlers,

<h4>Objectives</h4>Extracorporeal cardiopulmonary resuscitation (eCPR) is increasingly used due to its beneficial outcomes and results compared with conventional CPR. Data after eCPR for acute kidney injury (AKI) are lacking. We sought to investigate factors predicting AKI in patients who underwent eCPR.<h4>Methods</h4>From January 2016 until December 2020, patients who underwent eCPR at ... Read more >>

Perfusion (Perfusion)
[2021, :2676591211049767]

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Levosimendan administration is not associated with increased risk of bleeding and blood transfusion requirement in patients undergoing off-pump coronary artery bypass grafting: a retrospective study from single center.

Li-Hong Wang, Xiao-Hong Wang, Jie-Chao Tan, Li-Xian He, Run-Qiao Fu, Yong Lin, Yun-Tai Yao,

<h4>Background</h4>Levosimendan (LEVO) is a positive inotropic drug which could increase myocardial contractility and reduce the mortality rate in cardiac surgical patients. However, Whether LEVO is associated with postoperative bleeding and blood transfusion in cardiac surgical patients is controversial. Therefore, the current study was designed to investigate the impact of LEVO ... Read more >>

Perfusion (Perfusion)
[2021, :2676591211049022]

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Extra-corporeal membrane oxygenation and emergency C-section for a pregnant COVID-19 positive patient.

Alejandro Quintero, Eric E Vinck, Luz E Pérez, José J Escobar, Juan C Rendón, Juan D Uribe,

<h4>Introduction</h4>Data on extra-corporeal membrane oxygenation (ECMO) therapy for pregnant patients with Coronavirus 2019 (COVID-19) infection are limited. Here we report a case of an emergency cesarean section performed while the COVID-19 positive mother was on ECMO support.<h4>Case report</h4>A 36-year-old COVID-19 positive patient at 26 weeks gestational age presented with respiratory ... Read more >>

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[2021, :2676591211049769]

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Procainamide pharmacokinetics during extracorporeal membrane oxygenation.

Nicholas J Vollmer, Erica D Wittwer, Andrew N Rosenbaum, Patrick M Wieruszewski,

Procainamide is a useful agent for management of ventricular arrhythmia, however its disposition and appropriate dosing during extracorporeal membrane oxygenation (ECMO) is unknown. We report experience with continuous procainamide infusion in a critically ill adult requiring venoarterial ECMO for incessant ventricular tachycardia. Pharmacokinetic analysis of procainamide and its metabolite, N-acetylprocainamide ... Read more >>

Perfusion (Perfusion)
[2021, :2676591211050606]

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The importance of perioperative and complication management in the treatment of pheochromocytoma crisis with venoarterial extracorporeal membrane oxygenation (V-A ECMO): a case report and review of the literature.

Jiayi Chen, Guangyong Jin, Ying Zhu, Wei Hu, Huadong He, Changrong Wang, Xueying Cai,

<h4>Purpose</h4>In this article, we aimed to elaborate on perioperative and complication management in treatment of pheochromocytoma crisis with extracorporeal membrane oxygenation (ECMO).<h4>Material and methods</h4>We report a case of relatively rare grant paraganglioma-induced pheochromocytoma crisis leading to severe circulatory failure, treated with venoarterial extracorporeal membrane oxygenation (V-A ECMO) as a bridge ... Read more >>

Perfusion (Perfusion)
[2021, :2676591211049314]

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Clinical monitoring of activated clotting time during cardiothoracic surgery: comparing the Hemochron® Response and Hemochron® Signature Elite.

Roland F Hoffmann, Sandra Horsten, Massimo A Mariani, Adrianus J de Vries,

<h4>Introduction</h4>The Activated Clotting Time (ACT) is commonly used to manage anticoagulation during cardiac surgery. The aim of this study was to compare the older manually operated Hemochron<sup>®</sup> Response and the automated Hemochron<sup>®</sup> Signature Elite.<h4>Methods</h4>In this observational study the clinically relevant differences of both devices were investigated simultaneously, using duplicate measurements, ... Read more >>

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[2021, :2676591211049316]

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Extracorporeal membrane oxygenation in Jehovah's Witness patients: Case report, literature review, and summary of recommendations.

Abrahán Mera, Eduard Argudo, María Martínez-Martínez, Clara Palmada, Camilo Bonilla, Andrés Pacheco, Luis Chiscano, Gemma Marín, Beatriz Lozano, Elisabet Gallart, Jordi Riera,

Extracorporeal Membrane Oxygenation (ECMO) is commonly associated with a high blood transfusion requirement. Jehovah's Witness patients present a particular challenge. The impossibility of transfusing blood cells and starting anticoagulation treatment are common contraindications for this supportive measure. Here we report the case of a Jehovah's Witness patient with refractory hypoxemia ... Read more >>

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[2021, :2676591211047774]

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Virtual 4th MiECT Symposium: Innovation and Future.

John M Murkin, Cyril Serrick, Polychronis Antonitsis, Kyriakos Anastasiadis, Prakash P Punjabi,

Perfusion (Perfusion)
[2021, 36(7):654-655]

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Conscious sedation versus general anesthesia for transcatheter aortic valve implantation in patients with severe chronic obstructive pulmonary disease.

Serkan Aslan, Ahmet Güner, Ali Rıza Demir, Emre Yılmaz, Ayşe Feyza Aslan, Ömer Çelik, Fatih Uzun, Mehmet Ertürk,

<h4>Introduction</h4>Chronic obstructive pulmonary disease (COPD) is considered a major risk factor for postoperative complications after transcatheter aortic valve implantation (TAVI). To date, there is no clear consensus on the best anesthesia management for these patients. We aimed to investigate the effects of types of anesthesia on clinical outcomes in patients ... Read more >>

Perfusion (Perfusion)
[2021, :2676591211045801]

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International survey of neuromonitoring and neurodevelopmental outcome in children and adults supported on extracorporeal membrane oxygenation in Europe.

Mirjana Cvetkovic, Giovanni Chiarini, Mirko Belliato, Thijs Delnoij, Paolo Zanatta, Fabio Silvio Taccone, Dinis Dos Reis Miranda, Mark Davidson, Nashwa Matta, Carl Davis, Hanneke IJsselstijn, Matthieu Schmidt, Lars Mikael Broman, Dirk W Donker, Dirk Vlasselaers, Piero David, Matteo Di Nardo, Ralf M Muellenbach, Thomas Mueller, Nicholas A Barrett, Roberto Lorusso, Jan Belohlavek, Aparna Hoskote,

<h4>Background</h4>Adverse neurological events during extracorporeal membrane oxygenation (ECMO) are common and may be associated with devastating consequences. Close monitoring, early identification and prompt intervention can mitigate early and late neurological morbidity. Neuromonitoring and neurocognitive/neurodevelopmental follow-up are critically important to optimize outcomes in both adults and children.<h4>Objective</h4>To assess current practice of ... Read more >>

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[2021, :2676591211042563]

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The impact of del Nido cardioplegia solution on blood morphology parameters.

Krzysztof Sanetra, Wojciech Domaradzki, Marek Cisowski, Rajesh Shrestha, Krzysztof Białek, Andrzej Bochenek, Justyna Jankowska-Sanetra, Piotr Paweł Buszman, Witold Gerber,

<h4>Background</h4>Crystalloid cardioplegic solutions are believed to reduce hemoglobin significantly and increase the transfusion rate. However, recent reports indicate that the del Nido cardioplegia may preserve blood morphology parameters.<h4>Methods</h4>In "The del Nido versus cold blood cardioplegia in aortic valve Replacement" trial patients undergoing aortic valve replacement were randomized into the del ... Read more >>

Perfusion (Perfusion)
[2021, :2676591211049020]

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Outcome of Impella 2.5 use in patients undergoing Percutaneous Coronary Intervention in Henan, China: a case series.

Rafiq Ahmed Bhat, Syed Manzoor Ali, Akanksha Rathi, Javaid Akhter Bhat, Raja Saqib Iqbal, Md Monowarul Islam, Syed Maqbool, Abhishek Tibrewal, Yongsheng Qu, You Zhang, Yuxiao Sun, Wentao Xiao, Chuanyu Gao,

<h4>Background</h4>Acute myocardial infarction (AMI) complicated by cardiogenic shock (AMI-CS) or heart failure is associated with an unacceptably high in-hospital mortality of 33%-55% and a lost chance to accept PCI (Percutaneous Coronary Intervention).<h4>Aim</h4>The aim of the study was to find out whether percutaneous hemodynamic support device Impella 2.5 improves prognosis of ... Read more >>

Perfusion (Perfusion)
[2021, :2676591211049018]

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The effects of glucose-free and glucose-containing dialysate during dialysis in MHD patients: a prospective cross-over study.

Minxia Li, Yuehong Li, Jiaxuan Lv, Huiying Xu, Xianglan Wu, Wen Wen, Wei Wang, Hua Yang,

<h4>Objective</h4>To investigate the effects of glucose-free and glucose-containing dialysates during dialysis in maintenance hemodialysis (MHD) patients by the prospective cross-over study, and detect glucose control methods in MHD patients.<h4>Methods</h4>A total of 66 MHD 18-75 years old patients in our hospital from Nov. 2019 to Mar. 2020 were recruited. All patients ... Read more >>

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[2021, :2676591211042726]

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CORRIGENDUM to "Extracorporeal membrane oxygenation for diffuse alveolar hemorrhage and severe hypoxemic respiratory failure from silicone embolism".

Perfusion (Perfusion)
[2021, :2676591211043695]

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Propensity matched analysis of minimally invasive versus conventional isolated aortic valve replacement.

Shwe Oo, Amilah Khan, Jeremy Chan, Sanjay Juneja, Massimo Caputo, Gianni Angelini, Cha Rajakaruna, Hunaid A Vohra,

<h4>Objective</h4>To analyse the early and mid-term outcome of patients undergoing conventional aortic valve replacement (AVR) versus minimally invasive via hemi-sternotomy aortic valve replacement (MIAVR).<h4>Methods</h4>A single centre retrospective study involving 653 patients who underwent isolated aortic valve replacement (AVR) either via conventional AVR (<i>n</i> = 516) or MIAVR (<i>n</i> = 137) between August 2015 and ... Read more >>

Perfusion (Perfusion)
[2021, :2676591211045802]

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Monocyte to high density lipoprotein ratio in patients with acute kidney injury after cardiac surgery.

Wenjuan Huang, Lei Wang, Xin Wan,

<h4>Background</h4>The Monocyte to high density lipoprotein ratio (MHR) has been postulated as a novel parameter associated with adverse renal and cardiovascular outcomes. In this study we investigated the association of MHR with cardiac surgery-associated acute kidney injury (CSA-AKI).<h4>Methods</h4>In this retrospective study, we analyzed the data pertaining to 1505 patients undergoing ... Read more >>

Perfusion (Perfusion)
[2021, :2676591211041945]

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Safety and utility of modified ultrafiltration in pediatric cardiac surgery.

David A Palanzo, Robert K Wise, Karl R Woitas, Akif Ündar, Joseph B Clark, John L Myers,

<h4>Introduction</h4>Modified ultrafiltration (MUF) is employed at the termination of cardiopulmonary bypass (CPB) in pediatric and neonatal patients undergoing congenital heart surgery to reduce the accumulation of total body water thus increasing the concentration of red blood cells and the other formed elements in the circulation. Modified ultrafiltration has been reported ... Read more >>

Perfusion (Perfusion)
[2021, :2676591211043697]

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An infant with suspected missed diagnosis of Williams syndrome failed weaning off CPB after surgical correction of pulmonary stenosis: a case report and literature review.

Yuan Yuan, Ronghua Zhou,

Williams syndrome (WS) is a rare congenital developmental disorder caused by the deletion of between 26 and 28 genes on chromosome 7q11.23. For patients with WS, in view of the particularity of the supravalvular aortic stenosis, choosing appropriate arterial cannula, maintaining higher perfusion pressure as well as strengthening myocardial protection ... Read more >>

Perfusion (Perfusion)
[2021, :2676591211046876]

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