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Journal Paediatr Int Child Health

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Zika virus in Brazil and worldwide: a narrative review.

Marlos Melo Martins, Roberto De Andrade Medronho, Antônio José Ledo Alves Da Cunha,

BACKGROUND:In the past 5 years, the Zika virus (ZIKV) has gone from being associated with mild infection to one of the most studied viruses worldwide. Between 2015 and 2016, the first reports of pregnant women with confirmed and/or suspected ZIKV infection described fetuses and newborns with severe congenital malformations, in particular ... Read more >>

Paediatr Int Child Health (Paediatrics and international child health)
[2020, :1-8]

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Human and novel coronavirus infections in children: a review.

Nipunie Rajapakse, Devika Dixit,

Coronaviruses, seven of which are known to infect humans, can cause a spectrum of clinical presentations ranging from asymptomatic infection to severe illness and death. Four human coronaviruses (hCoVs)-229E, HKU1, NL63 and OC43-circulate globally, commonly infect children and typically cause mild upper respiratory tract infections. Three novel coronaviruses of zoonotic ... Read more >>

Paediatr Int Child Health (Paediatrics and international child health)
[2020, :1-20]

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Relationship between low serum vitamin D status and urinary tract infection in children: a case-control study.

Hashem Mahmoudzadeh, Ahmad Ali Nikibakhsh, Sarvin Pashapour, Morteza Ghasemnejad-Berenji,

BACKGROUND:A link between vitamin D deficiency and susceptibility to bacterial and viral infections has recently been suggested. AIM:To investigate a possible association between vitamin D deficiency and urinary tract infection (UTI). METHODS:A case-control study was undertaken comprising 75 children aged 2-7 years with UTI (cases) compared with 75 healthy controls in ... Read more >>

Paediatr Int Child Health (Paediatrics and international child health)
[2020, :1-5]

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Zinc supplementation in childhood diarrhoea: an integral part of management.

Jogender Kumar, Arushi Yadav,

Paediatr Int Child Health (Paediatrics and international child health)
[2020, :1]

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Juvenile dermatomyositis presenting as complete heart block in a 10-year-old girl.

Ritwik Ghosh, Devlina Roy, Souvik Dubey, Khaled Abdelrahman, Amit Kumar Dey, Subhankar Chatterjee, Durjoy Lahiri, Biman Kanti Ray,

Juvenile dermatomyositis (JDM) is an auto-immune inflammatory condition associated with cardiac disorders including conduction abnormalities and myocardial dysfunction. The time of presentation of cardiac abnormalities can range from disease onset to after long-term follow-up, emphasising the importance of screening for cardiac involvement in JDM. A previously healthy 10-year-old girl presented ... Read more >>

Paediatr Int Child Health (Paediatrics and international child health)
[2020, :1-4]

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Vitamin B12 deficiency in Indian infants and children.

Jatinder Singh Goraya,

Paediatr Int Child Health (Paediatrics and international child health)
[2020, 40(2):75-77]

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An outbreak of dengue fever in children in the National Capital District of Papua New Guinea in 2016.

Francis Pulsan, Kone Sobi, Gwenda Anga, John Vince, Trevor Duke,

Background: The first documented outbreak of dengue which included cases with haemorrhage occurred in Papua New Guinea in 2016.Aim: To document the presentation and outcome of children with dengue in Port Moresby.Methods: This prospective cross-sectional descriptive study was conducted in Port Moresby General Hospital during a 6-month period from 6 ... Read more >>

Paediatr Int Child Health (Paediatrics and international child health)
[2020, :1-4]

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Allergic bronchopulmonary aspergillosis without asthma or cystic fibrosis.

Parminder Kaur, Pankaj Kumar, Shivani Randev, Vishal Guglani,

Allergic bronchopulmonary aspergillosis (ABPA) is an immunological disease complicating asthma or cystic fibrosis. An 8-year-old girl with no previous respiratory morbidity was diagnosed with ABPA on the basis of a raised eosinophil count and total and specific serum IgE levels combined with a positive skin-prick test for aspergillus and typical ... Read more >>

Paediatr Int Child Health (Paediatrics and international child health)
[2020, :1-3]

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Influenza virus infection complicated by bacterial necrotising pneumonia: two case reports.

Augusta Aragão Arruda, Joana Pacheco Fortuna, Ana Teresa Raposo, Marina Rita Paulo Soares, Juan António Gonçalves, Maria Fernanda Gomes,

Necrotising pneumonia (NP) is a potentially severe complication of community-acquired pneumonia characterised by necrosis of consolidated lung tissue. A 7-year-old boy and a 6-year-old boy are presented, both of whom had a complicated influenza infection which evolved into severe NP caused by Streptococcus pneumoniae. Both needed intensive care for invasive ... Read more >>

Paediatr Int Child Health (Paediatrics and international child health)
[2020, :1-5]

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Risk factors for mortality and management of children with complicated severe acute malnutrition at a tertiary referral hospital in Malawi.

Bryan J Vonasek, Msandeni Chiume, Heather L Crouse, Susan Mhango, Alexander Kondwani, Emily J Ciccone, Peter N Kazembe, Wilfred Gaven, Elizabeth Fitzgerald,

Background: Severe acute malnutrition (SAM) is a major cause of childhood mortality in resource-limited settings. The relationship between clinical factors and adherence to the 'WHO 10 Steps' and mortality in children with SAM is not fully understood.Methods: Data from an ongoing prospective observational cohort study assessing admission characteristics, management patterns ... Read more >>

Paediatr Int Child Health (Paediatrics and international child health)
[2020, :1-10]

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The change in prevalence of suspected non-alcoholic fatty liver disease in Korean adolescents from 2001 to 2017.

Seung Ha Park, Yong Eun Park, Jin Lee, Joon Hyuk Choi, Nae Yun Heo, Jongha Park, Tae Oh Kim, Jun Seong Hwang, Eunju Kim, Eun Hye Oh, Hang Jea Jang, Ha Young Park, Hyun Kuk Kim,

Aim: Data on trends in the prevalence of suspected non-alcoholic fatty liver disease (NAFLD) in adolescents are scarce, especially in the Asia-Pacific region. The purpose of this study was to determine whether the prevalence of suspected NAFLD changed between 2001-2005 and 2015-2017.Methods: Data were extracted from the Korea National Health ... Read more >>

Paediatr Int Child Health (Paediatrics and international child health)
[2020, :1-5]

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Prevalence and risk factors for neurocysticercosis in children with a first-onset seizure in rural North India.

Amit Kumar Mital, Priyanka Choudhary, R B Jain,

Background: Neurocysticercosis (NCC) is a parasitic infection acquired by consuming food and water contaminated by the faeces of a Taenia solium tapeworm carrier. It is an important cause of acquired seizures and also the common identifiable cause of new-onset seizures in children.Methods: A hospital-based prospective cross-sectional study of NCC was ... Read more >>

Paediatr Int Child Health (Paediatrics and international child health)
[2020, :1-8]

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Fatal congenital tuberculosis owing to late diagnosis of maternal tuberculosis: case report and review of congenital tuberculosis in China.

Jing-Min Sun, Chang Wang, Dan-Qun Jin, Fang Deng,

Congenital tuberculosis (TB) is rare and the prognosis is poor if not detected early. The diagnosis is often delayed owing to non-specific clinical presentation, misdiagnosis and undiagnosed maternal TB during pregnancy. A 12-day-old girl presented with a 5-day history of fever, cough, poor feeding and respiratory distress. Her mother had ... Read more >>

Paediatr Int Child Health (Paediatrics and international child health)
[2020, :1-5]

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Nebulised normal saline in moderate acute bronchiolitis and pneumonia in a low- to middle-income country: a randomised trial in Papua New Guinea.

Gordon Pukai, Trevor Duke,

Background: Acute lower respiratory tract infections are the commonest cause of hospitalisation in young children and supportive care remains the cornerstone of management. A randomised open trial was undertaken at the Port Moresby General Hospital Children's Emergency Department (CED) to determine whether nebulised normal saline had beneficial effects.Methods: Children <2 years ... Read more >>

Paediatr Int Child Health (Paediatrics and international child health)
[2020, :1-6]

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Acute haemorrhagic pericarditis: an unusual presentation of Chlamydophila pneumoniae pneumonia infection.

Fatma Zehra Oztek Celebi, Ali Fettah, Sule Yesil, Tamer Yoldas, Gonul Tanir, Meltem Akcaboy, Saliha Senel,

Chlamydophila pneumoniae, a common cause of respiratory tract infections, rarely leads to serious conditions. A 13-year-old boy with serologically confirmed C. pneumoniae infection presented with pneumonia complicated by pericardial and bilateral pleural effusions. He had a large haemorrhagic pericardial effusion from which 1000 ml of fluid was aspirated over 10 days and ... Read more >>

Paediatr Int Child Health (Paediatrics and international child health)
[2020, :1-4]

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Neonatal hyperbilirubinaemia and type I diabetes: an unsolved enigma.

Jogender Kumar, Jaivinder Yadav,

Paediatr Int Child Health (Paediatrics and international child health)
[2020, 40(1):72-73]

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Nurse-led implementation of ETAT+ is associated with reduced mortality in a children's hospital in Freetown, Sierra Leone.

Sandra Hands, Madeleine Verriotis, Ayeshatu Mustapha, Hany Ragab, Christopher Hands,

Background: In the wake of the Ebola virus disease (EVD) epidemic in Sierra Leone, secondary care facilities faced an increase in admissions with few members of medical staff available to assess and treat patients. This led to long waiting times in hospital outpatient departments. The study was undertaken in the ... Read more >>

Paediatr Int Child Health (Paediatrics and international child health)
[2020, :1-8]

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Thrombotic thrombocytopenic purpura in a 2.5-year-old boy with dengue infection: a rare complication.

Rajasekhar Reddy Gogireddy, Vasanth Kumar, Suchitra Ranjit, Rajeswari Natraj, Priyavarthini Venkatachalapathy, Indira Jayakumar, Saravanan Margabandhu,

Acute kidney injury (AKI) is a neglected and least studied complication of dengue. AKI secondary to thrombotic thrombocytopenic purpura (TTP) in dengue is extremely rare and there are few case reports. A 2.5-year-old boy with dengue who developed TTP in the critical phase of illness is described. He presented with ... Read more >>

Paediatr Int Child Health (Paediatrics and international child health)
[2020, 40(2):135-138]

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Neonatal hyperbilirubinaemia and type 1 diabetes: an unsolved enigma.

Pei-Fen Liao, Hui-Hsien Pan, Jeng-Dau Tsai, Tung-Wei Hung, Ji-Nan Sheu,

Paediatr Int Child Health (Paediatrics and international child health)
[2020, 40(2):139-140]

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The use of immature platelet fraction to predict time to platelet recovery in patients with dengue infection.

Ampaiwan Chuansumrit, Nopporn Apiwattanakul, Nongnuch Sirachainan, Karan Paisooksantivatana, Athipat Athipongarporn, Noppawan Tangbubpha, Praguywan Kadegasem, Kanchana Tangnararatchakit, Sutee Yoksan,

Background: In dengue infection, knowing time to platelet recovery is essential for optimal management.Aims: To determine a predictor for platelet recovery in patients with dengue infection.Methods: Platelet count and immature platelet fraction (IPF) from daily blood samples of patients with dengue infection during hospitalisation and 1-4 weeks after discharge were retrospectively ... Read more >>

Paediatr Int Child Health (Paediatrics and international child health)
[2020, 40(2):124-128]

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Management of neonatal jaundice in low- and middle-income countries.

Tina M Slusher, Yvonne E Vaucher,

Abbreviations: ABE: acute bilirubin encephalopathy; ABR: auditory evoked brainstem response; BIND: bilirubin-induced neurological dysfunction; EBT: exchange blood transfusions; HIC: high-income countries; KSD: kernicterus spectrum disorder; LED: light-emitting diode; LMIC: low- and middle-income countries; SNH: severe neonatal jaundice or hyperbilirubinaemia; TcB: transcutaneous bilirubinometry; TSB: total serum bilirubin. ... Read more >>

Paediatr Int Child Health (Paediatrics and international child health)
[2020, 40(1):7-10]

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Acceptability and uptake of an electronic decision-making tool to support the implementation of IMCI in primary healthcare facilities in KwaZulu-Natal, South Africa.

Cecilie Jensen, Neil H McKerrow, Gabrielle Wills,

Background: Despite progress in reducing child mortality, preventable child deaths remain a challenge in South Africa. Poor implementation of Integrated Management of Childhood Illness (IMCI) guidelines has been well described, and the reported barriers to implementation include a lack of user-friendly implementation tools.Aim: To investigate whether an electronic decision support ... Read more >>

Paediatr Int Child Health (Paediatrics and international child health)
[2019, :1-12]

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Risk of metabolic syndrome and early vascular markers for atherosclerosis in obese Indonesian adolescents.

Indah K Murni, Dian C Sulistyoningrum, Rina Susilowati, Madarina Julia,

Background: The prevalence of childhood obesity has increased in low- and middle-income countries, including Indonesia. It is important to identify risk factors for cardiovascular disease in obese adolescents in this region.Aim: To assess the risk of metabolic syndrome and early vascular markers for atherosclerosis in obese Indonesian adolescentsMethods: A cross-sectional ... Read more >>

Paediatr Int Child Health (Paediatrics and international child health)
[2020, 40(2):117-123]

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Serum periostin levels in acute rheumatic fever: is it useful as a new biomarker?

Serdar Epçaçan, Esra Yücel,

Background: Acute rheumatic fever (ARF) continues to be a public health problem in low- and middle-income countries. Because there is no specific laboratory test for the exact diagnosis of ARF, the diagnosis is made by the modified Jones criteria. Periostin is an extracellular matrix protein which has been shown to ... Read more >>

Paediatr Int Child Health (Paediatrics and international child health)
[2020, 40(2):111-116]

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Efficacy of zinc supplementation in the management of acute diarrhoea: a randomised controlled trial.

Lakkana Rerksuppaphol, Sanguansak Rerksuppaphol,

Background: Zinc has been recommended for the treatment of acute diarrhoea; however, there are heterogeneous reports regarding its efficacy.Aim: This study investigated the efficacy of zinc supplementation on the treatment outcomes of children admitted to hospital with acute diarrhoea.Methods: A double-blind, randomised, placebo-controlled trial was conducted in the Srinakharinwirot University ... Read more >>

Paediatr Int Child Health (Paediatrics and international child health)
[2020, 40(2):105-110]

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