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Neurodevelopment of HIV-exposed uninfected children in Cape Town, South Africa.

Hlengiwe P Madlala, Landon Myer, Thokozile R Malaba, Marie-Louise Newell,

BACKGROUND:Evidence shows that antiretroviral (ART) exposure is associated with neurodevelopmental delays in human immunodeficiency virus (HIV)-exposed uninfected (HEU) children. However, there are few insights into modifiable maternal and child factors that may play a role in improving neurodevelopment in HEU children. We used a parent-centric neurodevelopment tool, Ages & Stages ... Read more >>

PLoS One (PloS one)
[2020, 15(11):e0242244]

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Fragile heroes. The psychological impact of the COVID-19 pandemic on health-care workers in Italy.

Chiara Conti, Lilybeth Fontanesi, Roberta Lanzara, Ilenia Rosa, Piero Porcelli,

This survey-based study aimed to explore the mental health status and psychological care needs of 933 health-care workers in Italy during the COVID-19 outbreak. Sociodemographic data, exposure to COVID-19, perception of psychological care needs, depression, anxiety, somatization, and post-traumatic symptoms were concurrently assessed. The majority of the sample (71%) suffered ... Read more >>

PLoS One (PloS one)
[2020, 15(11):e0242538]

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New proposed cut-off of waist circumference for central obesity as risk factor for diabetes mellitus: Evidence from the Indonesian Basic National Health Survey.

Dante Saksono Harbuwono, Dicky Levenus Tahapary, Tri Juli Edi Tarigan, Em Yunir,

BACKGROUND:Waist circumference (WC) measurement is practical to define central obesity. However, WC cut-off point might be differ based on different race or ethnicity. This study aims to analyze the optimal WC cut-off point to identify T2DM risk among Indonesian population. METHOD:We analyzed the secondary data of national based cross-sectional study ... Read more >>

PLoS One (PloS one)
[2020, 15(11):e0242417]

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The metabotyping of an East African cassava diversity panel: A core collection for developing biotic stress tolerance in cassava.

Laura Perez-Fons, Tatiana M Ovalle, M N Maruthi, John Colvin, Luis Augusto Becerra Lopez-Lavalle, Paul D Fraser,

Cassava will have a vital role to play, if food security is to be achieved in Sub-Saharan Africa, especially Central and East Africa. The whitefly Bemisia tabaci poses a major threat to cassava production by small holder farmers in part due to their role as a vector of cassava mosaic ... Read more >>

PLoS One (PloS one)
[2020, 15(11):e0242245]

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Tissue expression of antigens of ABH blood groups in species of New World Monkeys (Aotus infulatus, Callithrix jacchus, Sapajus apella and Saimiri sciureus).

Délia Cristina Figueira Aguiar, Washington Luiz Assunção Pereira, Gyselly de Cássia Bastos de Matos, Klena Sarges Marruaz da Silva, Rosane do Socorro Pompeu de Loiola, Tereza Cristina Oliveira Corvelo,

ABH antigens are histo-antigens, but were first described on the surface of human erythrocytes. They are found in those cells only in great apes and humans, while in more primitive animals they are found in tissues and body fluids. ABH antigens are mainly distributed in tissues that are in contact ... Read more >>

PLoS One (PloS one)
[2020, 15(11):e0241487]

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Non-antibiotic medication use in an Indonesian community cohort 0-18 months of age.

Jarir At Thobari, Cahya Dewi Satria, Yohanes Ridora, Emma Watts, Amanda Handley, Jane Standish, Novilia S Bachtiar, Jim P Buttery, Yati Soenarto, Julie E Bines,

BACKGROUND:Rational medication use for treatment is mandatory, particularly in children as they are vulnerable to possible hazards of drugs. Understanding the medication use pattern is of importance to identify the problems of drug therapy and to improve the appropriate use of medication among this population. METHODS:A post-hoc study of the ... Read more >>

PLoS One (PloS one)
[2020, 15(11):e0242410]

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Race, explicit racial attitudes, implicit racial attitudes, and COVID-19 cases and deaths: An analysis of counties in the United States.

George B Cunningham, Lisa T Wigfall,

OBJECTIVES:To examine the potential moderating effects of explicit racial attitudes and implicit racial attitudes on the relationship between percent of Black county residents and COVID-19 cases and deaths. METHODS:We collected data from a variety of publicly available sources for 817 counties in the US. (26% of all counties). Cumulative COVID-19 ... Read more >>

PLoS One (PloS one)
[2020, 15(11):e0242044]

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A taxonomic and molecular survey of the pteridophytes of the Nectandra Cloud Forest Reserve, Costa Rica.

Joel H Nitta, Atsushi Ebihara, Alan R Smith,

Floristic surveys are crucial to the conservation of biodiversity, but the vast majority of such surveys are limited to listing species names, and few take into account the evolutionary history of species. Here, we combine classical taxonomic and molecular phylogenetic (DNA barcoding) approaches to catalog the biodiversity of pteridophytes (ferns ... Read more >>

PLoS One (PloS one)
[2020, 15(11):e0241231]

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Factors associated with successful completion of outpatient parenteral antibiotic therapy in an area with a high prevalence of multidrug-resistant bacteria: 30-day hospital admission and mortality rates.

Thais Cristina Garbelini Salles, Santiago Grau Cerrato, Tatiana Fiscina Santana, Eduardo Alexandrino Medeiros,

OBJECTIVES:To identify factors associated with hospital admission and mortality within the first 30 days after enrolment in an outpatient parenteral antimicrobial therapy (OPAT) program, also analysing adequacy of the treatment regimen and clinical outcomes. PATIENTS AND METHODS:This was a retrospective cohort study conducted between October 2016 and June 2017 in ... Read more >>

PLoS One (PloS one)
[2020, 15(11):e0241595]

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Musical emotions in the absence of music: A cross-cultural investigation of emotion communication in music by extra-musical cues.

Marco Susino, Emery Schubert,

Research in music and emotion has long acknowledged the importance of extra-musical cues, yet has been unable to measure their effect on emotion communication in music. The aim of this research was to understand how extra-musical cues affect emotion responses to music in two distinguishable cultures. Australian and Cuban participants ... Read more >>

PLoS One (PloS one)
[2020, 15(11):e0241196]

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Formal Comment: Romer study fails at following core principles of reanalysis.

Jeffrey A Bridge, Joel B Greenhouse, Kelly J Kelleher, John V Campo,

PLoS One (PloS one)
[2020, 15(11):e0237184]

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Burnout among medical students in Cyprus: A cross-sectional study.

Antonios Nteveros, Marios Kyprianou, Artemios Artemiadis, Antrianthi Charalampous, Kallistheni Christoforaki, Stephanos Cheilidis, Orestis Germanos, Panagiotis Bargiotas, Andreas Chatzittofis, Panagiotis Zis,

OBJECTIVES:The primary aim was to estimate the burnout prevalence among all medical students at the Medical School of the University of Cyprus. Secondary aims were to ascertain the predictors of burnout and its relationship with lifestyle habits, sleep quality and mental health. BACKGROUND:Burnout in the healthcare sector has drawn significant ... Read more >>

PLoS One (PloS one)
[2020, 15(11):e0241335]

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Using the National Trauma Data Bank (NTDB) and machine learning to predict trauma patient mortality at admission.

Evan J Tsiklidis, Carrie Sims, Talid Sinno, Scott L Diamond,

A 400-estimator gradient boosting classifier was trained to predict survival probabilities of trauma patients. The National Trauma Data Bank (NTDB) provided 799233 complete patient records (778303 survivors and 20930 deaths) each containing 32 features, a number further reduced to only 8 features via the permutation importance method. Importantly, the 8 ... Read more >>

PLoS One (PloS one)
[2020, 15(11):e0242166]

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Angiopoietin-2 is released during anaphylactic hypotension in anesthetized and unanesthetized rats.

Tao Zhang, Toshishige Shibamoto, Mamoru Tanida, Makoto Taniguchi, Yuhichi Kuda, Wei Yang, Yasutaka Kurata,

Angiopoietin (Angpt)-2, a permeability-increasing growth factor, is involved in vascular leakage of sepsis and acute lung injury, and could be released from endothelium in response to anaphylaxis-related secretagogues such as histamine and leukotrienes, or cytokines. However, roles of Angpt-2 in the hyperpermeability during systemic anaphylaxis are not known. Thus, we ... Read more >>

PLoS One (PloS one)
[2020, 15(11):e0242026]

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A novel quantitative electroencephalography subtype with high alpha power in ADHD: ADHD or misdiagnosed ADHD?

Jun Byeon, Tae Young Choi, Geun Hui Won, Jaewon Lee, Jun Won Kim,

This study investigated quantitative electroencephalography (QEEG) subtypes as auxiliary tools to assess Attention Deficit Hyperactivity Disorder (ADHD). A total of 74 subjects (58 male and 16 female) were assessed using the Korean version of the Diagnostic Interview Schedule for Children Version IV and were assigned to one of three groups: ... Read more >>

PLoS One (PloS one)
[2020, 15(11):e0242566]

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Transcriptome profile of carbon catabolite repression in an efficient l-(+)-lactic acid-producing bacterium Enterococcus mundtii QU25 grown in media with combinations of cellobiose, xylose, and glucose.

Yuh Shiwa, Haruko Fujiwara, Mao Numaguchi, Mohamed Ali Abdel-Rahman, Keisuke Nabeta, Yu Kanesaki, Yukihiro Tashiro, Takeshi Zendo, Naoto Tanaka, Nobuyuki Fujita, Hirofumi Yoshikawa, Kenji Sonomoto, Mariko Shimizu-Kadota,

Enterococcus mundtii QU25, a non-dairy lactic acid bacterium of the phylum Firmicutes, is capable of simultaneously fermenting cellobiose and xylose, and is described as a promising strain for the industrial production of optically pure l-lactic acid (≥ 99.9%) via homo-fermentation of lignocellulosic hydrolysates. Generally, Firmicutes bacteria show preferential consumption of ... Read more >>

PLoS One (PloS one)
[2020, 15(11):e0242070]

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MiR-424-5p regulates cell cycle and inhibits proliferation of hepatocellular carcinoma cells by targeting E2F7.

Yichao Zhao, Chaoqian Zhu, Qing Chang, Peng Peng, Jie Yang, Chunmei Liu, Yang Liu, Xiaonan Chen, Yuanguang Liu, Ran Cheng, Yijie Wu, Xiaotang Wu, Liang Hu, Jun Yin,

OBJECTIVE:This study aims to explore the mechanism of the miR-424-5p/E2F7 axis in hepatocellular carcinoma (HCC) and provide new ideas for targeted therapy of HCC. METHODS:Bioinformatics analysis was used to identify the target differentially expressed miRNA in HCC and predict its target gene. qRT-PCR was employed to verify the expression of ... Read more >>

PLoS One (PloS one)
[2020, 15(11):e0242179]

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Employee burnout and positive dimensions of well-being: A latent workplace spirituality profile analysis.

Laura Dal Corso, Alessandro De Carlo, Francesca Carluccio, Daiana Colledani, Alessandra Falco,

In recent years, a new and promising construct has attracted the attention of organizational research: Workplace spirituality. To investigate the role of workplace spirituality in organizational contexts, two studies were carried out. Study 1 explored the mediation role of workplace spirituality in the relationship between positive supervisor behaviors and employee ... Read more >>

PLoS One (PloS one)
[2020, 15(11):e0242267]

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Histological, immunohistochemical and transcriptomic characterization of human tracheoesophageal fistulas.

Erwin Brosens, Janine F Felix, Anne Boerema-de Munck, Elisabeth M de Jong, Elisabeth M Lodder, Sigrid Swagemakers, Marjon Buscop-van Kempen, Ronald R de Krijger, Rene M H Wijnen, Wilfred F J van IJcken, Peter van der Spek, Annelies de Klein, Dick Tibboel, Robbert J Rottier,

Esophageal atresia (EA) and tracheoesophageal fistula (TEF) are relatively frequently occurring foregut malformations. EA/TEF is thought to have a strong genetic component. Not much is known regarding the biological processes disturbed or which cell type is affected in patients. This hampers the detection of the responsible culprits (genetic or environmental) ... Read more >>

PLoS One (PloS one)
[2020, 15(11):e0242167]

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Comparing subjective intoxication with risky single-occasion drinking in a European sample.

Carolin Kilian, Jakob Manthey, Jacek Moskalewicz, Emanuele Scafato, Lidia Segura García, Janusz Sieroslawski, Jürgen Rehm,

In most epidemiological literature, harmful drinking-a drinking pattern recognized as closely linked to alcohol-attributable diseases-is recorded using the measure risky single-occasion drinking (RSOD), which is based on drinking above a certain quantity. In contrast, subjective intoxication (SI) as an alternative measure can provide additional information, including the drinker's subjective perceptions ... Read more >>

PLoS One (PloS one)
[2020, 15(11):e0241433]

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Fault diagnosis method of submersible screw pump based on random forest.

Minzheng Jiang, Tiancai Cheng, Kangxing Dong, Shufan Xu, Yulong Geng,

The difficulty in directly determining the failure mode of the submersible screw pump will shorten the life of the system and the normal production of the oil well. This thesis aims to identify the fault forms of submersible screw pump accurately and efficiently, and proposes a fault diagnosis method of ... Read more >>

PLoS One (PloS one)
[2020, 15(11):e0242458]

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Using night time lights to find regional inequality in India and its relationship with economic development.

Abhishek Singhal, Sohini Sahu, Siddhartha Chattopadhyay, Abhijit Mukherjee, Soumendra N Bhanja,

Due to unavailability of consistent income data at the sub-state or district level in developing countries, it is difficult to generate consistent and reliable economic inequality estimates at the disaggregated level. To address this issue, this paper employs the association between night time lights and economic activities for India at ... Read more >>

PLoS One (PloS one)
[2020, 15(11):e0241907]

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Factor analysis for the clustering of cardiometabolic risk factors and sedentary behavior, a cross-sectional study.

Tsung-Ying Tsai, Pai-Feng Hsu, Chung-Chi Lin, Yuan-Jen Wang, Yaw-Zon Ding, Teh-Ling Liou, Ying-Wen Wang, Shao-Sung Huang, Wan-Leong Chan, Shing-Jong Lin, Jaw-Wen Chen, Hsin-Bang Leu,

BACKGROUND:Few studies have reported on the clustering pattern of CVD risk factors, including sedentary behavior, systemic inflammation, and cadiometabolic components in the general population. OBJECTIVE:We aimed to explore the clustering pattern of CVD risk factors using exploratory factor analysis to investigate the underlying relationships between various CVD risk factors. METHODS:A ... Read more >>

PLoS One (PloS one)
[2020, 15(11):e0242365]

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Prediction of anterior chamber volume after implantation of posterior chamber phakic intraocular lens.

Yuki Takagi, Takashi Kojima, Tomoya Nishida, Tomoaki Nakamura, Kazuo Ichikawa,

PURPOSE:To predict the anterior chamber volume (ACV) after implantable collamer lens (ICL) implantation based on ICL size and parameters of anterior segment optical coherence tomography (AS-OCT). DESIGN:Retrospective study. METHODS:This study included 222 eyes of 222 patients who underwent ICL implantation at Nagoya Eye Clinic. The patients were divided into two ... Read more >>

PLoS One (PloS one)
[2020, 15(11):e0242434]

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Providing person-centered care for patients with complex healthcare needs: A qualitative study.

Vincent J T Peters, Bert R Meijboom, Jan Erik H Bunt, Levinus A Bok, Marianne W van Steenbergen, J Peter de Winter, Esther de Vries,

BACKGROUND:People with chronic conditions have complex healthcare needs that lead to challenges for adequate healthcare provision. Current healthcare services do not always respond adequately to their needs. A modular perspective, in particular providing visualization of the modular service architecture, is promising for improving the responsiveness of healthcare services to the ... Read more >>

PLoS One (PloS one)
[2020, 15(11):e0242418]

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