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Monitoring maternal near miss/severe maternal morbidity: A systematic review of global practices.

Natalie England, Julia Madill, Amy Metcalfe, Laura Magee, Stephanie Cooper, Charleen Salmon, Kamala Adhikari,

There is international interest in monitoring severe events in the obstetrical population, commonly referred to as maternal near miss or severe maternal morbidity. These events can have significant consequences for individuals in this population and further study can inform practices to reduce both maternal morbidity and mortality. Numerous surveillance systems ... Read more >>

PLoS ONE (PloS one)
[2020, 15(5):e0233697]

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Different wheat cultivars exhibit variable responses to inoculation with arbuscular mycorrhizal fungi from organic and conventional farms.

David García de León, Tanel Vahter, Martin Zobel, Mati Koppel, Liina Edesi, John Davison, Saleh Al-Quraishy, Wael N Hozzein, Mari Moora, Jane Oja, Martti Vasar, Maarja Öpik,

The present study aimed to investigate the effects of arbuscular mycorrhizal (AM) fungal communities originating from organic and conventional agriculture on wheat growth and yield. Six different spring wheat cultivars released in different years in north and central European countries were considered. We hypothesised that AM fungal inoculum collected from ... Read more >>

PLoS ONE (PloS one)
[2020, 15(5):e0233878]

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A pilot randomized trial of incentive strategies to promote HIV retesting in rural Uganda.

Gabriel Chamie, Alex Ndyabakira, Kara G Marson, Devy M Emperador, Moses R Kamya, Diane V Havlir, Dalsone Kwarisiima, Harsha Thirumurthy,

Retesting for HIV is critical to identifying newly-infected persons and reinforcing prevention efforts among at-risk adults. Incentives can increase one-time HIV testing, but their role in promoting retesting is unknown. We sought to test feasibility and acceptability of incentive strategies, including commitment contracts, to promote HIV retesting among at-risk adults ... Read more >>

PLoS ONE (PloS one)
[2020, 15(5):e0233600]

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Brain interstitial pH changes in the subacute phase of hypoxic-ischemic encephalopathy in newborn pigs.

Gábor Remzső, János Németh, Viktória Varga, Viktória Kovács, Valéria Tóth-Szűki, Kai Kaila, Juha Voipio, Ferenc Domoki,

Brain interstitial pH (pHbrain) alterations play an important role in the mechanisms of neuronal injury in neonatal hypoxic-ischemic encephalopathy (HIE) induced by perinatal asphyxia. The newborn pig is an established large animal model to study HIE, however, only limited information on pHbrain alterations is available in this species and it ... Read more >>

PLoS ONE (PloS one)
[2020, 15(5):e0233851]

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Canonical signaling by TGF family members in mesenchymal stromal cells is dispensable for hematopoietic niche maintenance under basal and stress conditions.

Joseph Ryan Krambs, Grazia Abou Ezzi, Juo-Chin Yao, Daniel C Link,

Mesenchymal stromal cells are an important component of the bone marrow hematopoietic niche. Prior studies showed that signaling from members of the transforming growth factor (TGF) superfamily in mesenchymal stromal cells is required for normal niche development. Here, we assessed the impact of TGF family signaling on niche maintenance and ... Read more >>

PLoS ONE (PloS one)
[2020, 15(5):e0233751]

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How robust is the own-group face recognition bias? Evidence from first- and second-generation East Asian Canadians.

Andy H Ng, Jennifer R Steele, Joni Y Sasaki, Meghan George,

There is mounting evidence that North Americans are better able to remember faces of targets who belong to the same social group, and this is true even when the social groups are experimentally created. Yet, how Western cultural contexts afford the development of this own group face recognition bias remains ... Read more >>

PLoS ONE (PloS one)
[2020, 15(5):e0233758]

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Correction: Low incidence of antibiotic-resistant bacteria in south-east Sweden: An epidemiologic study on 9268 cases of bloodstream infection.

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[This corrects the article DOI: 10.1371/journal.pone.0230501.]. ... Read more >>

PLoS ONE (PloS one)
[2020, 15(5):e0234276]

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What and how are students taught about communicating risks to patients? Analysis of a medical curriculum.

Franziska Baessler, Joshua Weidlich, Sophie Schweizer, Anja Ciprianidis, Marina Bartolovic, Ali Zafar, Michael Wolf, Fabienne Louise Wagner, Tabea Chiara Baumann, André L Mihaljevic, Beate Ditzen, Daniela Roesch-Ely, Christoph Nikendei, Jobst-Hendrik Schultz,

Communication is a core competence in medical care. Failure of physicians to properly communicate inherent risks of medical interventions has been linked with inadequate training at school. This study analyses a medical curriculum for assessing the content and quality of teaching risk communication to students. A checklist based on the ... Read more >>

PLoS ONE (PloS one)
[2020, 15(5):e0233682]

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A tps1Δ persister-like state in Saccharomyces cerevisiae is regulated by MKT1.

Patrick A Gibney, Anqi Chen, Ariel Schieler, Jonathan C Chen, Yifan Xu, David G Hendrickson, R Scott McIsaac, Joshua D Rabinowitz, David Botstein,

Trehalose metabolism in yeast has been linked to a variety of phenotypes, including heat resistance, desiccation tolerance, carbon-source utilization, and sporulation. The relationships among the several phenotypes of mutants unable to synthesize trehalose are not understood, even though the pathway is highly conserved. One of these phenotypes is that tps1Δ ... Read more >>

PLoS ONE (PloS one)
[2020, 15(5):e0233779]

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A study on the association between eye movements and regular mouthing movements (RMMs) in normal fetuses between 24 to 39 weeks of gestation.

Kana Maehara, Seiichi Morokuma, Kazushige Nakahara, Hikohiro Okawa, Kiyoko Kato,

Regular Mouthing Movements (RMMs) are movements in which lips and lower jaw movements occur regularly and can be observed in the fetus using transabdominal ultrasonic tomography. In near term infants, it is known that RMMs form clusters during the quiet sleep period. The notation of RMMs is not uniform, and ... Read more >>

PLoS ONE (PloS one)
[2020, 15(5):e0233909]

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Origin of HAV strains responsible for 2016-2017 outbreak among MSM: Viral phylodynamics in Lazio region.

Claudia Minosse, Francesco Messina, Anna Rosa Garbuglia, Silvia Meschi, Paola Scognamiglio, Maria Rosaria Capobianchi, Giuseppe Ippolito, Simone Lanini,

In Europe HAV infection occurs mainly among specific risk groups, such as consumers of specific food. Sexual transmission of HAV has been demonstrated, particularly among Men-Who-Have-Sex-With-Men (MSM), causing MSM-specific outbreaksin Europe. Here we report a molecular epidemiologic and phylodynamic analysis on HAV sequences in Lazio (central Italy)to identify genetic background ... Read more >>

PLoS ONE (PloS one)
[2020, 15(5):e0234010]

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Population status, foraging ecology and activity pattern of golden jackal (Canis aureus) in Guangua Ellala Forest, Awi Zone, north west Ethiopia.

Tilahun Gashe, Mesele Yihune,

A study on population status, foraging ecology and activity pattern of golden jackal (Canis aureus) was conducted from October 2017 to August 2018. Data was collected through direct observation (total count, focal and scan sampling) and faecal dropping analysis. Data was analyzed using descriptive statistics and compared with Chi-square test, ... Read more >>

PLoS ONE (PloS one)
[2020, 15(5):e0233556]

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Resistance of the murine cornea to bacterial colonization during experimental dry eye.

Stephanie J Wan, Sophia Ma, David J Evans, Suzanne M J Fleiszig,

The healthy cornea is remarkably resistant to infection, quickly clearing deliberately inoculated bacteria such as Pseudomonas aeruginosa and Staphylococcus aureus. Contrasting with the adjacent conjunctiva and other body surfaces, it also lacks a resident viable bacterial microbiome. Corneal resistance to microbes depends on intrinsic defenses involving tear fluid and the ... Read more >>

PLoS ONE (PloS one)
[2020, 15(5):e0234013]

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Evolution and influencing factors of China's rural population distribution patterns since 1990.

Hua Zhang, Simeng Zhang, Zheda Liu,

Population is a major production factor in rural development in China, which makes the study of rural population distribution patterns at different times and the factors influencing the population distribution an important foundation for understanding the issues in rural China and moving forward with the implementation of rural revitalization strategies. ... Read more >>

PLoS ONE (PloS one)
[2020, 15(5):e0233637]

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Hybrid between Danio rerio female and Danio nigrofasciatus male produces aneuploid sperm with limited fertilization capacity.

Mitsuru Endoh, Fumika Shima, Miloš Havelka, Rei Asanuma, Etsuro Yamaha, Takafumi Fujimoto, Katsutoshi Arai,

In the Danio species, interspecific hybridization has been conducted in several combinations. Among them, only the hybrid between a zebrafish (D. rerio) female and a spotted danio (D. nigrofasciatus) male was reported to be fertile. However, beyond these investigations, by means of reproductive biology, gametes of the hybrid have also ... Read more >>

PLoS ONE (PloS one)
[2020, 15(5):e0233885]

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Alterations of functional and structural connectivity in patients with brain metastases.

Bo Hua, Xin Ding, Minghua Xiong, Fanyu Zhang, Yi Luo, Jurong Ding, Zhongxiang Ding,

Metastases are the most prevalent tumors in the brain and are commonly associated with high morbidity and mortality. Previous studies have suggested that brain tumors can induce a loss of functional connectivity and alter the brain network architecture. Little is known about the effect of brain metastases on whole-brain functional ... Read more >>

PLoS ONE (PloS one)
[2020, 15(5):e0233833]

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What is meant by validity in maternal and newborn health measurement? A conceptual framework for understanding indicator validation.

Lenka Benova, Ann-Beth Moller, Kathleen Hill, Lara M E Vaz, Alison Morgan, Claudia Hanson, Katherine Semrau, Shams Al Arifeen, Allisyn C Moran,

Rigorous monitoring supports progress in achieving maternal and newborn mortality and morbidity reductions. Recent work to strengthen measurement for maternal and newborn health highlights the existence of a large number of indicators being used for this purpose. The definitions and data sources used to produce indicator estimates vary and challenges ... Read more >>

PLoS ONE (PloS one)
[2020, 15(5):e0233969]

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Storage stability of five steroids and in dried blood spots for newborn screening and retrospective diagnosis of congenital adrenal hyperplasia.

Nóra Grecsó, Anita Zádori, Ilona Szécsi, Ákos Baráth, Zsolt Galla, Csaba Bereczki, Péter Monostori,

Congenital adrenal hyperplasia (CAH) is a severe inherited disorder of cortisol biosynthesis that is potentially lethal or can seriously affect quality of life. For the first time, we aimed to assess the stability of 21-deoxycortisol (21Deox), 11-deoxycortisol (11Deox), 4-androstenedione (4AD), 17-hydroxyprogesterone (17OHP) and cortisol (Cort), diagnostic for CAH, in dried ... Read more >>

PLoS ONE (PloS one)
[2020, 15(5):e0233724]

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Changes in benzoxazinoid contents and the expression of the associated genes in rye (Secale cereale L.) due to brown rust and the inoculation procedure.

Magdalena Święcicka, Marta Dmochowska-Boguta, Wacław Orczyk, Agnieszka Grądzielewska, Anna Stochmal, Mariusz Kowalczyk, Leszek Bolibok, Monika Rakoczy-Trojanowska,

Benzoxazinoids (BXs) are secondary metabolites with diverse functions, but are primarily involved in protecting plants, mainly from the family Poaceae, against insects and fungal pathogens. Rye is a cereal crop that is highly resistant to biotic stresses. However, its susceptibility to brown rust caused by Puccinia recondita f. sp. secalis ... Read more >>

PLoS ONE (PloS one)
[2020, 15(5):e0233807]

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Optimizing PMTCT efforts by repeat HIV testing during antenatal and perinatal care in resource-limited settings: A longitudinal assessment of HIV seroconversion.

Ivy Mushamiri, Maureen Adudans, Donald Apat, Yanis Ben Amor,

Mother to child transmission (MTCT) of HIV remains a challenge in resource-limited settings. Central to elimination of MTCT is effective Provider Initiated HIV Counseling and Testing (PICT). Research has shown that conducting PICT only at the initial antenatal care (ANC) visit fails to benefit pregnant women who seroconvert later in ... Read more >>

PLoS ONE (PloS one)
[2020, 15(5):e0233396]

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Sevoflurane versus ketamine+diazepam anesthesia for assessing systemic and hepatic hemodynamics in rats with non-cirrhotic portal hypertension.

José Ignacio Fortea, Marta Puerto, Carolina Fernández-Mena, Iris Asensio, María Arriba, Jorge Almagro, Juan Bañares, Cristina Ripoll, Rafael Bañares, Javier Vaquero,

The selection of the anesthetic regime is a crucial component in many experimental animal studies. In rodent models of liver disease, the combination of ketamine and diazepam (KD), generally by the intramuscular (i.m.) route, has traditionally been the anesthesia of choice for the evaluation of systemic and hepatic hemodynamics but ... Read more >>

PLoS ONE (PloS one)
[2020, 15(5):e0233778]

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Role of ambient pressure in self-heating torrefaction of dairy cattle manure.

Takanori Itoh, Kazunori Iwabuchi, Naohiro Maemoku, Siyao Chen, Katsumori Taniguro,

This paper describes the role of ambient pressure in self-heating torrefaction of livestock manure. We explored the initiating temperatures required to cause self-heating of wet dairy cattle manure at different ambient pressures (0.1, 0.4, 0.7, and 1.0 MPa). Then, we conducted proximate, elemental, and calorific analyses of biochar torrefied at ... Read more >>

PLoS ONE (PloS one)
[2020, 15(5):e0233027]

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Statistical analysis of the impact of environmental temperature on the exponential growth rate of cases infected by COVID-19.

George Livadiotis,

We perform a statistical analysis for understanding the effect of the environmental temperature on the exponential growth rate of the cases infected by COVID-19 for US and Italian regions. In particular, we analyze the datasets of regional infected cases, derive the growth rates for regions characterized by a readable exponential ... Read more >>

PLoS ONE (PloS one)
[2020, 15(5):e0233875]

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Timing and rate of nitrogen fertilization influence maize yield and nitrogen use efficiency.

Benjamin Davies, Jeffrey A Coulter, Paulo H Pagliari,

Timing and rate of nitrogen (N) fertilizer application can influence maize (Zea mays L.) grain yield, N uptake, and nitrogen use efficiency (NUE) parameters, but results have been inconsistent across the upper Midwest. This study compared single (fall and preplant) and split applications of differing N rates for maize under ... Read more >>

PLoS ONE (PloS one)
[2020, 15(5):e0233674]

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Functional NHE1 expression is critical to blood brain barrier integrity and sumatriptan blood to brain uptake.

Erika Liktor-Busa, Kiera T Blawn, Kathryn L Kellohen, Beth M Wiese, Vani Verkhovsky, Jared Wahl, Anjali Vivek, Seph M Palomino, Thomas P Davis, Todd W Vanderah, Tally M Largent-Milnes,

Disruption of blood-brain barrier integrity and dramatic failure of brain ion homeostasis including fluctuations of pH occurs during cortical spreading depression (CSD) events associated with several neurological disorders, including migraine with aura, traumatic brain injury and stroke. NHE1 is the primary regulator of pH in the central nervous system. The ... Read more >>

PLoS ONE (PloS one)
[2020, 15(5):e0227463]

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