Full Text Journal Articles in
Journal Nat. Prod. Res.

Advertisement

Find full text journal articles






A pair of new isocoumarin enantiomers of Ludwigia hyssopifolia.

Jinyan Zhang, Chang Liu, Yibing Lv, Jianhua Wei, Bing Li, Guangfeng Liao, Rumei Lu, Xinzhou Yang,

A pair of new isocoumarin derivative enantiomers, (S)-(-)-3-(3,3-dichloro-2-hydroxy-propyl)-4-chlorine-6,8-dihydroxy-isochromen-1- one (1a) and (R)-(+)-3-(3,3-dichloro-2-hydroxy-propyl)-4-chlorine-6,8-dihydroxy-isochromen-1- one (1 b), as well as seven known compounds (2-8) were isolated from Ludwigia hyssopifolia. Compounds 1a and 1 b were confirmed to be a pair of enantiomers by chiral HPLC-CD analysis, and the structure of compound 1 was determined ... Read more >>

Nat. Prod. Res. (Natural product research)
[2020, :1-8]

Cited: 0 times

View full text PDF listing >>



Four new prenylflavonol glycosides from the leaves of Cyclocarya paliurus.

Zi-Jun Ye, Hui-Hui Sun, Zu-Hui Chen, Jian-Ping Wu, Jing Li, Hui Zhu, Lu-Lu Huang, Xi-Wen Chang, Sai-Yu Ou, Wen-Xuan Wang, Xiao-Ai He, Gang-Zhi Zhu, Kang-Ping Xu,

Four new prenylflavonol glycosides (1-4) along with two known analogues (5-6) were isolated from the leaves of Cyclocarya paliurus for the first time. The structures of these compounds were characterized by comprehensive analysis of 1 D, 2 D NMR, HRESIMS, UV data and enzymatic hydrolysis. In bioassays, compounds 1-4 were evaluated for ... Read more >>

Nat. Prod. Res. (Natural product research)
[2020, :1-8]

Cited: 0 times

View full text PDF listing >>



Advertisement

A new cycloartane triterpene and other phytoconstituents from the aerial parts of Euphorbia dendroides.

Ahmed R Hassan, Ahmed Ashour, Yhiya Amen, Maki Nagata, Sayed A El-Toumy, Kuniyoshi Shimizu,

New cycloartane-type triterpene 23 R/S-3β-hydroxycycloart-24-ene-23-methyl ether 1a,b (as an C-23 epimeric mixture), along with ten known compounds, including 1 steroid, 3 fatty acids and 6 triterpenoids were isolated from the aerial parts of Euphorbia dendroides L. (Euphorbiaceae). The known compounds (2-11) were identified using 1 D & 2 D-NMR spectra and by comparison ... Read more >>

Nat. Prod. Res. (Natural product research)
[2020, :1-9]

Cited: 0 times

View full text PDF listing >>



Morin exhibits leukemic cellular apoptosis through caspase pathway.

Wander Lopes Pereira, Tânia Toledo de Oliveira, Milton Masahiko Kanashiro, Marcelo Augusto Filardi, Marcelo Rocha da Costa, Liovando Marciano da Costa,

The present study investigated the possibility of apoptosis-inducing activity in human leukemia U-937 and THP-1 cells by the flavonoid morin. The treatments were evaluated by using the MTT and LDH assays; analysis of mitochondrial membrane potential (ΔΨm) was evaluated by flow cytometry, cell death by apoptosis was confirmed by fluorescence ... Read more >>

Nat. Prod. Res. (Natural product research)
[2020, :1-5]

Cited: 0 times

View full text PDF listing >>



A new steroidal glycoside from the fruits of Solanum myriacanthum.

Masateru Ono, Mizuki Shimode, Shuhei Tsutsumi, Shin Yasuda, Masafumi Okawa, Junei Kinjo, Hiroyuki Miyashita, Tsuyoshi Ikeda, Hitoshi Yoshimitsu, Toshihiro Nohara,

A new cholestane-type steroidal glycoside, solamyriaside A (1), was isolated from the fruits of Solanum myriacanthum Dunal (Solanaceae), along with two known steroidal glycosides, namely, solaviaside A (2) and aculeatiside A (3), and three known steroidal alkaloid glycosides, namely, solamargine (4), khasianine (5) and solasonine (6), which were isolated for ... Read more >>

Nat. Prod. Res. (Natural product research)
[2020, :1-8]

Cited: 0 times

View full text PDF listing >>



Govanoside B, a new steroidal saponin from rhizomes of Trillium govanianum.

Prithvi Pal Singh, Patil Shivprasad Suresh, Prateek Singh Bora, Vinod Bhatt, Upendra Sharma,

Trillium govanianum, commonly known as Nag Chhatri and Teen Patra, is a popular herbal supplement traditionally used for curing different inflammatory and sexual disorders, infection and wound healing. Steroidal saponins are considered as active components of this species. The present study demonstrated the isolation of nine steroidal saponins, including one ... Read more >>

Nat. Prod. Res. (Natural product research)
[2020, :1-9]

Cited: 0 times

View full text PDF listing >>



Chemical study, antioxidant activity, and genotoxicity and cytotoxicity evaluation of Ruellia angustiflora.

Fernanda B Pires, Carolina B Dolwitsch, Gustavo A Ugalde, Bryan B Menezes, Marlos Eduardo Z Fontana, Roberta C Rieffeld, Michele R Sagrillo, Liliana Essi, Marcio Antonio Mazutti, Marcelo B da Rosa, Ionara Regina Pizzutti,

Ruellia angustiflora (Acanthaceae) is known as flower-of-fire, and its leaves are traditionally employed to promote wound healing. This study was aimed at extracting and characterizing the chemical constituents of the extracts of R. angustiflora obtained by ultrasound-assisted and supercritical fluid extractions, and subsequently investigate their antioxidant potential and cyto-genotoxicity. The ... Read more >>

Nat Prod Res (Natural product research)
[2020, :1-6]

Cited: 0 times

View full text PDF listing >>



Angiotensin-converting enzyme inhibitors from Salvia elegans Vahl.

Ana Silvia Gutiérrez-Román, Manasés Gonzalez-Cortazar, Gabriela Trejo-Tapia, Maribel Herrera-Ruiz, Alejandro Zamilpa, Ernesto Sanchéz-Mendoza, Natividad Giovana De la Cruz-Sanchez, Enrique Jiménez-Ferrer,

Phytochemical research of the acetate and methanol extracts of the aerial parts (flowers, leaves and stems) of Salvia elegans allowed to obtain seventeen known compounds (1-17): three of them (4, 5, 14), had already been described for this species, while the others (1-3, 6-13, 15-17) are described for the first ... Read more >>

Nat. Prod. Res. (Natural product research)
[2020, :1-6]

Cited: 0 times

View full text PDF listing >>



Velucarpin D, a new pterocarpan from the stems of Dalbergia velutina and its cytotoxicity.

Sutin Kaennakam, Edwin Risky Sukandar, Siriwat Hongnak, Kitiya Rassamee, Pongpun Siripong, Santi Tip-Pyang,

A new pterocarpan, named velucarpin D (1), along with nine known pterocarpans (2-10) were isolated from the stems of Dalbergia velutina. Their structures were determined by spectroscopic analysis. All isolated compounds were evaluated for their cytotoxicity against five human cancer cell lines (KB, HeLa S-3, MCF-7, Hep G2, and HT-29). ... Read more >>

Nat. Prod. Res. (Natural product research)
[2020, :1-6]

Cited: 0 times

View full text PDF listing >>



Triculata A, a novel compound from Tricyrtis maculata (D. Don) J. F. Macbr. with biological properties.

Li Ren, Yun-Ze Wang, Wei Zhang, Rui Zhou, Ming Zhao, Zhi-Shu Tang, Jing Sun, Dong-Bo Zhang,

A novel compound, triculata A (1), and seven known compounds were obtained from the Tricyrtis maculata (D. Don) J. F. Macbr.. The structure of the new compound was determined by extensive spectroscopic methods, and its absolute configuration was assigned by single-crystal X-ray diffraction analysis. Compound 1 features a rare naphtho[b,c]pyran ... Read more >>

Nat. Prod. Res. (Natural product research)
[2020, :1-9]

Cited: 0 times

View full text PDF listing >>



Eight new cyclopentenone and cyclohexenone derivatives from the marine-derived fungus Aspergillus sp. SCSIO 41501 by OSMAC strategy.

Fei-Hua Yao, Xiao Liang, Shu-Hua Qi,

One strain many compounds (OSMAC) strategy was an effective method to activate the silent biosynthetic genes of microorganisms. Comparison with our previous investigations on the secondary metabolites of the marine-derived fungus Aspergillus sp. SCSIO 41501, in this study, three new cyclopentenone derivatives, aspergispones A-C (1-3), and five new cyclohexenone derivatives, ... Read more >>

Nat. Prod. Res. (Natural product research)
[2020, :1-10]

Cited: 0 times

View full text PDF listing >>



Solieritide A, a new polyketide from the red alga Solieria sp.

Ting-Ting Liu, Xiao-Jian Liao, Shi-Hai Xu, Bing-Xin Zhao,

A new polyketide, solieritide A (1), along with six known ones (2-7), had been isolated from the red alga Solieria sp. The structures of these compounds were elucidated by spectroscopic analysis. The absolute configuration of 1 was determined by the method of X-ray diffraction. Compound 1 was a rare polyketide ... Read more >>

Nat. Prod. Res. (Natural product research)
[2020, :1-7]

Cited: 0 times

View full text PDF listing >>



Synthesis and cytotoxicity of novel 14α-O-(andrographolide-3-subsitutedisoxazole-5-carboxylate) derivatives.

Sudhakar Mokenapelli, Jayaprakash Rao Yerrabelli, Neeladrisingha Das, Partha Roy, Prasad Rao Chitneni,

Simple and efficient method was established for the synthesis of a new family of 14α-O-(andrographolide-3-subsitutedisoxazole-5-carboxylate) derivatives (10a-j) from naturally occurring andrographolide (1) by selective esterification with propiolic acid at C-14 using protection and deprotection strategy followed by metal free 1,3-dipolar cycloaddition with aryl nitrile oxides. All the synthesised derivatives were ... Read more >>

Nat. Prod. Res. (Natural product research)
[2020, :1-7]

Cited: 0 times

View full text PDF listing >>



Picraquanines A-C, three new phenolic derivatives from the stems of Picrasma quassioides.

Rui Xu, Dongdong Zhang, Fangfang Shu, Zehai Long, Yiming Li, Zhengtao Wang, Li Yang, Rui Wang,

Three new phenolic derivatives, picraquanines A-C (1-3), along with 6 known ones 4-9 were obtained from the stems of Picrasma quassioides (D. Don) Benn. The new structures were determined by extensive spectroscopic data analysis, including IR, HRESIMS, 1H-NMR, 13C-NMR, HSQC, HMBC, 1H-1H COSY experiments. The absolute configuration of 1 was ... Read more >>

Nat. Prod. Res. (Natural product research)
[2020, :1-7]

Cited: 0 times

View full text PDF listing >>



Synthesis, structural assignments and antiinfective activities of 3-O-benzyl-carvotacetone and 3-hydroxy-2-isopropyl-5-methyl-p-benzoquinone.

Veronica M Masila, Albert J Ndakala, Robert Byamukama, Jacob O Midiwo, Rahab W Kamau, Mei Wang, Mallika Kumarihamy, Jianping Zhao, Matthias Heydreich, Ilias Muhammad,

In an attempt to synthesize carvotacetone analogues, new 3-O-benzyl-carvotacetone (10) and previously reported 3-hydroxy-2-isopropyl-5-methyl-p-benzoquinone (11) were synthesized from piperitone (7). In this work, we describe the synthesis of 10 and other analogues from 7. Luche reduction of 7 to cis-piperitol (8), followed by benzylation yielded 3-O-benzyl-piperitol (9). Riley oxidation of ... Read more >>

Nat. Prod. Res. (Natural product research)
[2020, :1-9]

Cited: 0 times

View full text PDF listing >>



R-Hexitronic acid, a new tetronic acid derivative isolated from a soil fungus FG9RK.

Kenneth G Ngwoke, Dina H El-Kashef, Georgios Daletos, Elena Ancheeva, Zhen Liu, Festus B C Okoye, Charles O Esimone, Peter Proksch,

A new tetronic acid derivative (1) together with terrestric acid (2), a known metabolite of Penicillium species, was isolated from the soil fungus, FG9RK following fermentation on solid rice medium. The structure of 1 was elucidated by one- and two-dimensional NMR and MS measurements. The absolute configuration of the oxygenated ... Read more >>

Nat. Prod. Res. (Natural product research)
[2020, :1-6]

Cited: 0 times

View full text PDF listing >>



Morindaquinone, a new bianthraquinone from Morinda coreia roots.

Suwadee Chokchaisiri, Yuttana Siriwattanasathien, Chopaka Thongbamrer, Apichart Suksamrarn, Thitima Rukachaisirikul,

Phytochemical investigation of the roots of Morinda coreia led to the isolation of one new bianthraquinone, morindaquinone (1), together with 12 known compounds, soranjidiol (2), rubiadin-1-methyl ether (3), 2-methoxy-1,3,6-trihydroxyanthraquinone (4), 1-hydroxy-2-methylanthraquinone (5), tectoquinone (6), nordamnacanthal (7), damnacanthal (8), 2-formylanthraquinone (9), 3-hydroxy-2-hydroxymethylanthraquinone (10), lucidin-ω-methyl ether (11), scopoletin (12) and (+)-mellein (13). ... Read more >>

Nat. Prod. Res. (Natural product research)
[2019, :1-7]

Cited: 1 time

View full text PDF listing >>



A new xanthone and a biphenyl from the flower and twig extracts of Garcinia mckeaniana.

Chiramet Auranwiwat, Thunwadee Limtharakul, Stephen G Pyne, Roonglawan Rattanajak, Sumalee Kamchonwongpaisan,

The phytochemical investigation of the flower and twig extracts of Garcinia mckeaniana yielded a new xanthone, mckeanianone F (1) and a new biphenyl, mckeaniabiphenyl (2) together with 15 known compounds. The isolated compounds were characterized using spectroscopic techniques and mass spectrometry. Some of the isolated compounds from the twigs exhibited ... Read more >>

Nat Prod Res (Natural product research)
[2019, :1-6]

Cited: 0 times

View full text PDF listing >>



Onoseriolide, from Hedyosmum racemosum, induces cytotoxicity and apoptosis in human colon cancer cells.

Luis Miguel Guamán-Ortiz, Natalia Bailon-Moscoso, Vladimir Morocho, Daisy Vega-Ojeda, Fernando Gordillo, Alírica I Suárez,

The number of colon cancer patients is increasing, and new alternatives for treatment are important. We focused on the sesquiterpene lactone onoseriolide from Hedyosmum racemosum, which is widely used in traditional medicine. This compound was evaluated to determine its cytotoxic effect and the mechanism of cell death that is induced ... Read more >>

Nat. Prod. Res. (Natural product research)
[2019, :1-5]

Cited: 0 times

View full text PDF listing >>



Identification and antimicrobial properties of a new alkaloid produced by marine-derived Verrucosispora sp. FIM06-0036.

Ming-Hong Chen, Yun-Yang Lian, Dong-Sheng Fang, Li Chen, Jia Jia, Wen-Long Zhang, Ru Lin, Yang Xie, Hong-Kai Bi, Hong Jiang,

The actinomycete strain FIM06-0036 was isolated from marine sponge sample collected from the East China Sea and identified as Verrucosispora sp. based upon the results of 16S rRNA sequence analysis. One new alkaloid, 2-ethylhexyl 1H-imidazole-4-carboxylate (1), together with a known alkaloid butyl 1H-imidazole-4-carboxylate (2) was obtained from the fermentation products ... Read more >>

Nat. Prod. Res. (Natural product research)
[2019, :1-7]

Cited: 0 times

View full text PDF listing >>



Regioselective synthesis and structures of anti-cancer 20(R)-ginsenoside Rg3 derivatives.

Hong-Yu Fan,

Regioselective synthesis of three novel palmitates of 20(R)-ginsenoside Rg3 was accomplished via a facile strategy, along with complete assignment of their 1H and 13C NMR resonances by 1D and 2D NMR (1H-1H COSY, DEPT 135, HSQC, HMBC, and NOESY) techniques. The derivatives were tested for in vitro anti-proliferative activities against ... Read more >>

Nat. Prod. Res. (Natural product research)
[2020, 34(14):1962-1970]

Cited: 0 times

View full text PDF listing >>



Asymmetric Synthesis of Chiral Flavan-3-Ols.

Zehua Yang, Fang Xiao, Yinxiang Zhang, Zaoduan Wu, Xing Zheng,

Flavan-3-ols are a series of natural products widely present in plants and show versatile biological activities. The structures of such compounds are characterized by owing two adjacent chiral centers and three rings. Their interesting structures and promising biological activities have driven increasing research developments toward the preparation of enantioenriched flavan-3-ols. ... Read more >>

Nat. Prod. Res. (Natural product research)
[2019, 33(20):2995-3010]

Cited: 0 times

View full text PDF listing >>



Gallic acid as main product in the water extractives of Quercus frainetto ten.

Paola Cetera, Maurizio D'Auria, Marisabel Mecca, Luigi Todaro,

The autoclave extraction of Hungarian oak (Quercus frainetto Ten.) wood gave 5.3% extractives. The chloroform soluble fraction obtained from the extracts of Q. frainetto allows to identify sesamin. The insoluble fraction contains mainly ribose and mannose. Water extraction in autoclave of thermo-treated Q. frainetto wood gave a lower amount of ... Read more >>

Nat. Prod. Res. (Natural product research)
[2019, 33(19):2864-2867]

Cited: 0 times

View full text PDF listing >>



Chemical constituents from the deep sea-derived Streptomyces xiamenensis MCCC 1A01570 and their effects on RXRα transcriptional regulation.

Wei-Xiang Lin, Chun-Lan Xie, Mi Zhou, Man-Li Xia, Ting-Ting Zhou, Hai-Feng Chen, Xian-Wen Yang, Quan Yang,

From the deep sea-derived Streptomyces xiamenensis MCCC 1A01570, eight cyclic dipeptides (1-8) and five phenolics (9-13) were obtained. Cyclo-(I-Pro-D-Leu) (4) could moderately promote the gene transcriptional function of nuclear receptor RXRα, while 2, 3, and 13 showed weak reduction in RXRα gene transcriptional activities induced by 9-cis-retinoid acid (RA). These ... Read more >>

Nat. Prod. Res. (Natural product research)
[2020, 34(10):1461-1464]

Cited: 0 times

View full text PDF listing >>



Penicindopene A, a new indole diterpene from the deep-sea fungus Penicillium sp. YPCMAC1.

Lijun Liu, Wei Xu, Shumin Li, Mengying Chen, Yongjun Cheng, Wangjun Yuan, Zhongbin Cheng, Qin Li,

A new indole diterpene, named penicindopene A (1), together with seven known compounds (2 - 8), was isolated from the deep-sea fungus Penicillium sp. YPCMAC1. The structure of penicindopene A was elucidated by extensive spectroscopic analyses (1 D and 2 D NMR, and HRESIMS data), in addition to the ECD calculations for the assignments ... Read more >>

Nat. Prod. Res. (Natural product research)
[2019, 33(20):2988-2994]

Cited: 3 times

View full text PDF listing >>



Advertisement

Disclaimer
0.9835 s