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Journal Laryngoscope

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Inflammatory Effects of Thickened Water on the Lungs in a Murine Model of Recurrent Aspiration.

Nogah Nativ-Zeltzer, Rumi Ueha, Yuval Nachalon, Betty Ma, Gabrielle Pastenkos, Clay Swackhamer, Gail M Bornhorst, Maureen A Lefton-Greif, Johnathon D Anderson, Peter C Belafsky,

OBJECTIVE:Liquid thickeners are commonly recommended in individuals with dysphagia and recurrent aspiration as a strategy for pneumonia prevention. The goal of this study was to examine the effects of small amounts of aspirated liquid thickener on the lungs. STUDY DESIGN:Animal model. Prospective small animal clinical trial. METHODS:Adult Sprague Dawley rats ... Read more >>

Laryngoscope (The Laryngoscope)
[2020, :]

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Significance of Nodal Metastasis in Parotid Gland Acinar Cell Carcinoma.

Peter Moon, Mahbuba Tusty, Vasu Divi, Uchechukwu C Megwalu,

OBJECTIVES:To evaluate the rate of lymph node metastasis in parotid gland acinar cell carcinoma, to identified factors associated with increased risk of metastasis, and to evaluate the effect of nodal metastasis on survival. METHODS:This is a retrospective cohort study utilizing data from a large population-based cancer database. Data were extracted ... Read more >>

Laryngoscope (The Laryngoscope)
[2020, :]

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Oncological and Functional Outcomes of Primary and Salvage Total Laryngectomy.

Andy Bertolin, Marco Lionello, Claudia Zanotti, Leonardo Franz, Luciano Giacomelli, Giuseppe Rizzotto, Gino Marioni,

OBJECTIVES:To evaluate and compare the oncological and functional outcomes of total laryngectomies (TL) performed as first line treatment or for salvage after failure of conservative approaches for treating advanced laryngeal carcinoma (LSCC). STUDY DESIGN:A retrospective cohort study. METHODS:A cohort of 217 patients who underwent TL was divided according to whether ... Read more >>

Laryngoscope (The Laryngoscope)
[2020, :]

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Distinct Clinical Pathology and Microbiota in Chronic Rhinosinusitis With Nasal Polyps Endotypes.

Elrayah E Abbas, Chuan Li, Ao Xie, Shan Lu, Li Tang, Yinhui Liu, Ayman Elfadil, Shu Wen,

OBJECTIVES/HYPOTHESIS:Eosinophilic and noneosinophilic chronic rhinosinusitis with nasal polyps (ECRSwNP and NECRSwNP) show distinguished clinical pathology, but their underlying mechanism remains unclear. We aimed to investigate the clinical, hematological, and histopathological changes in chronic rhinosinusitis with nasal polyps (CRSwNP) endotypes and its association with microbiota. STUDY DESIGN:A comparative cross-sectional study. METHODS:A ... Read more >>

Laryngoscope (The Laryngoscope)
[2020, :]

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Iatrogenic Cholesteatoma Presenting as Neck Mass.

Joseph B Vella, P Ashley Wackym, He Wang, Sudipta T Roychowdhury,

We present a rare iatrogenic cholesteatoma of the neck in a ten year old male four years after tympanomastoidectomy, an entity that to our knowledge has not been published in the literature for over 30 years. Furthermore, we discuss the diagnostic uncertainty of typical magnetic resonance imaging protocols for pediatric ... Read more >>

Laryngoscope (The Laryngoscope)
[2020, :]

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Prenatal Imaging Findings Predict Obstructive Fetal Airways Requiring EXIT.

Harrison Cash, Randall Bly, Vanessa Masco, Manjiri Dighe, Edith Cheng, Shani Delaney, Kimberly Ma, Jonathan A Perkins,

OBJECTIVE:Detection of fetal airway compromise through imaging raises the possible need for ex utero intrapartum treatment (EXIT) procedures. Despite EXIT procedures involving massive resource utilization and posing increased risk to the mother, decisions for EXIT are usually based on anecdotal experience. Our objectives were to analyze prenatal consultations with potential ... Read more >>

Laryngoscope (The Laryngoscope)
[2020, :]

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In Reference to Prognostic Value of Tumor Staging: Predicting Nodal Metastases in Cutaneous Squamous Cell Carcinoma.

Paola Barriera-Silvestrini, Thomas Knackstedt,

Laryngoscope (The Laryngoscope)
[2020, :]

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Influence of Insurance Status and Demographic Factors on Outcomes Following Tracheostomy.

Rohini Bahethi, Christopher Park, Anthony Yang, Mingyang Gray, Kevin Wong, Alfred Iloreta, Mark Courey,

OBJECTIVES/HYPOTHESIS:Little data exists regarding the relationship between socioeconomic and demographic factors and tracheostomy outcomes. The goal of this study was to determine associations between socioeconomic status (SES), demographic factors, and insurance status with hospital length of stay (LOS), intensive care unit (ICU) LOS, and mortality following tracheostomy. STUDY DESIGN:Retrospective cohort ... Read more >>

Laryngoscope (The Laryngoscope)
[2020, :]

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Is Familial Nonmedullary Thyroid Cancer A More Aggressive Type of Thyroid Cancer?

Limor Muallem Kalmovich, Basel Jabarin, Shlomit Koren, Karen Or, Efrat Marcus, Inna Tkacheva, Carlos Benbassat, Miriam Steinschneider,

OBJECTIVES:Familial non-medullary thyroid cancer (FNMTC) is a distinct entity, increasingly diagnosed. By lacking an accurate genetic diagnostic test, its diagnosis is currently clinically based, with an ongoing debate over whether it has a more aggressive clinical behavior than sporadic non-medullary thyroid cancer (SNMTC). We seek to compare in this study, ... Read more >>

Laryngoscope (The Laryngoscope)
[2020, :]

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In Response to Letter to the Editor Regarding: Prognostic Value of Tumor Staging: Predicting Nodal Metastases in Cutaneous Squamous Cell Carcinoma.

Montana Upton, Ashley Kita, Jason Scapa, Maie St John,

Laryngoscope (The Laryngoscope)
[2020, :]

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Changes of Laryngeal and Extralaryngeal Symptoms and Findings in Laryngopharyngeal Reflux Patients.

Jérôme R Lechien, Francois Bobin, Vinciane Muls, Francois Mouawad, Giovanni Dapri, Didier Dequanter, Mihaela Horoi, Marie-Paule Thill, Alexandra Rodriguez Ruiz, Sven Saussez,

OBJECTIVES/HYPOTHESIS:To assess the evolution of laryngeal and extralaryngeal symptoms and findings of laryngopharyngeal reflux (LPR) throughout a 3-month to 9-month treatment. STUDY DESIGN:Prospective Controlled Study. METHODS:One hundred twenty-seven LPR patients and 123 healthy individuals were enrolled from four European hospitals. Patients were managed with a 3-month personalized treatment considering the ... Read more >>

Laryngoscope (The Laryngoscope)
[2020, :]

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Endoscopic Incudo-Malleolar Arthrodesis: A New Surgical Treatment for Incudo-Malleolar Subluxation.

Marco Bonali, Giulia Molinari, Livio Presutti, Francesco Maccarrone,

Laryngoscope (The Laryngoscope)
[2020, :]

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Predicting Functional Outcomes and Length of Stay Following Acoustic Neuroma Resection.

Omid Moshtaghi, Joe Saliba, Mihir Gupta, Pasha Mehranpour, Kareem O Tawfik, Yin Ren, Marc S Schwartz, Rick A Friedman,

OBJECTIVES:To examine whether simple mobility assessments can predict functional limitations and length of hospitalization after acoustic neuroma (AN) resection. STUDY DESIGN:Prospective case series. METHODS:A prospective clinical study of adult patients undergoing AN resection by either the translabyrinthine, retrosigmoid, or middle fossa approach was conducted at a tertiary center. Preoperative mobility ... Read more >>

Laryngoscope (The Laryngoscope)
[2020, :]

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Residual Epiphora After Successful Periocular Surgery for Facial Paralysis: Pathophysiology and Management.

Caleb J Fan, Shirley Hu, Matthew B Hirsch, Bruce K Moskowitz,

The prevalence of residual epiphora following successful periocular surgery for facial nerve paralysis can be as high as 30% or more. The pathophysiology of residual epiphora is complex, but identification of the etiology is paramount because the therapeutic approach varies accordingly. Treatments range from medical management of systemic disease to ... Read more >>

Laryngoscope (The Laryngoscope)
[2020, :]

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Does Adherence to Early Infant Hearing Detection and Intervention Guidelines Positively Impact Pediatric Speech Outcomes?

Matthew L Bush, Beth McNulty, Jennifer B Shinn,

Laryngoscope (The Laryngoscope)
[2020, :]

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An Open-Source Three-Dimensionally Printed Laryngeal Model for Injection Laryngoplasty Training.

Mark Lee, Chelston Ang, Katerina Andreadis, James Shin, Anaïs Rameau,

OBJECTIVES/HYPOTHESIS:A limited number of three-dimensionally (3D)-printed laryngeal simulators have been described in the literature, only one of which is specifically designed for percutaneous injection laryngoplasty (PIL) training and is currently of limited availability. This study describes the development and evaluation of a high-fidelity, open-source, low-cost 3D-printed simulator for PIL training, ... Read more >>

Laryngoscope (The Laryngoscope)
[2020, :]

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Patient-Perceived Nasal Appearance After Septorhinoplasty With Spreader Versus Extended Spreader Graft.

Rachel E Weitzman, Shekhar K Gadkaree, Natalie S Justicz, Robin W Lindsay,

OBJECTIVES/HYPOTHESIS:Standard spreader grafts (SSGs) are commonly used in septorhinoplasty to treat internal nasal valve narrowing and have been shown to improve nasal airway obstruction. Extended spreader grafts (ESGs) have also been proven effective for correcting nasal deviation. To date, the effectiveness of ESGs using patient-reported outcome measures has not been ... Read more >>

Laryngoscope (The Laryngoscope)
[2020, :]

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A Novel Presentation of the Acute Airway: Anti-IgLON5 Disease.

Jennifer Chen, Sarju Vasani,

Anti-IgLON5 disease is a newly discovered novel sleep disorder at the crossroads of neurology and immunology. In addition to the underlying sleep disorder, anti-IgLON5 manifests with progressive aerodigestive symptoms such as dysphagia, stridor, and vocal cord paresis in 90% cases and may present to the otolaryngologist. Herein we present a ... Read more >>

Laryngoscope (The Laryngoscope)
[2020, :]

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Case Report: Lateral Chest Placement of IPG for Hypoglossal Nerve Stimulator Implantation.

Jordan S Weiner,

Hypoglossal nerve stimulation for the treatment of obstructive sleep apnea is an increasingly common procedure. The hypoglossal nerve is stimulated by an implanted pulse generator that is placed in a subcutaneous pocket in the upper chest over the pectoralis muscle. A pressure sensor is placed through a separate incision between ... Read more >>

Laryngoscope (The Laryngoscope)
[2020, :]

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Voice and Stroboscopic Characteristics in Transgender Patients Seeking Gender-Affirming Voice Care.

VyVy N Young, Andrew Yousef, Nina W Zhao, Sarah L Schneider,

OBJECTIVE:Understanding transgender voice is in nascent stages. This study describes voice characteristics in treatment-seeking transwomen by comparing two validated questionnaires-Voice Handicap Index-10 (VHI-10) and Transsexual Voice Questionnaire (TVQMtF )-and reports incidence of abnormal stroboscopy findings and acoustic characteristics. METHODS:Retrospective review of transgender patients presenting to tertiary-care laryngology center between February ... Read more >>

Laryngoscope (The Laryngoscope)
[2020, :]

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An Intravagal Parathyroid Adenoma in the Poststyloid Parapharyngeal Space.

David C Shonka, Deepa Danan,

OBJECTIVES:Describe a case of an intravagal parathyroid adenoma. CASE:A 35-year-old male presented with symptomatic primary hyperparathyroidism and non-localizing imaging studies. Intraoperative venous sampling revealed a substantial gradient within the right internal jugular vein. Repeat imaging identified an enhancing lesion in the right parapharyngeal space at the skull base. An intravagal ... Read more >>

Laryngoscope (The Laryngoscope)
[2020, :]

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Endoscopic Muscle Repair of Right Internal Carotid Artery Rupture Following Endovascular Procedure.

Shravani Pathak, Todd Spock, Mingyang Gray, Katherine Liu, Raj Shrivastava, Alfred Iloreta,

Carotid artery blowout syndrome (CBS) is a deadly complication usually linked to head and neck cancer therapy. We present a different etiology of endoscopic CBS, a complication of endovascular coiling of an intracranial aneurysm, treated with sternocleidomastoid (SCM) muscle graft packing. Case Presentation: An otherwise healthy 55-year-old female presented to ... Read more >>

Laryngoscope (The Laryngoscope)
[2020, :]

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Transoral Removal of an Extruded Odontoid Screw Causing Dysphagia and Dysphonia.

Alisa Zhukhovitskaya, Arya N Shamie, Dinesh Chhetri,

A 77-year-old male underwent open reduction and internal fixation with placement of odontoid screws after sustaining C1 arch and odontoid fractures in a fall 14 months prior to presentation to the laryngology clinic for combined surgery with orthopedics. Serial imaging after the initial surgery demonstrated loosening of a screw and ... Read more >>

Laryngoscope (The Laryngoscope)
[2020, :]

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Telemedicine in Otolaryngology in the COVID-19 Era: Initial Lessons Learned.

Jason F Ohlstein, Jordan Garner, Masayoshi Takashima,

OBJECTIVES:The COVID-19 pandemic has led to unprecedented global changes in the delivery of healthcare over a short period of time. With the implementation of "shelter in place" orders, otolaryngology clinic visits at our institution were transitioned to Telemedicine. This change enabled the rapid characterization of the patients who accepted and ... Read more >>

Laryngoscope (The Laryngoscope)
[2020, :]

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Blue Light Laser Results in Less Vocal Fold Scarring Compared to KTP Laser in Normal Rat Vocal Folds.

R Jun Lin, Vladimir Iakovlev, Catherine Streutker, Daniel Lee, Mohammed Al-Ali, Jennifer Anderson,

OBJECTIVES:Preliminary investigations suggest that a novel blue light (BL) laser with a wavelength of 445 nm is comparable to the commonly utilized potassium titanyl phosphate (KTP) laser (532 nm) for treatment of various laryngeal pathologies. The objective of the current study is to make a direct histological comparison of the degree of ... Read more >>

Laryngoscope (The Laryngoscope)
[2020, :]

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