Full Text Journal Articles in
Journal Kidney Int.

Advertisement

Find full text journal articles






Results from the ERA-EDTA Registry indicate a high mortality due to COVID-19 in dialysis patients and kidney transplant recipients across Europe.

Kitty J Jager, Anneke Kramer, Nicholas C Chesnaye, Cécile Couchoud, J Emilio Sánchez-Álvarez, Liliana Garneata, Fréderic Collart, Marc H Hemmelder, Patrice Ambühl, Julia Kerschbaum, Camille Legeai, María Dolores Del Pino Y Pino, Gabriel Mircescu, Lionel Mazzoleni, Tiny Hoekstra, Rebecca Winzeler, Gert Mayer, Vianda S Stel, Christoph Wanner, Carmine Zoccali, Ziad A Massy,

The aim of this study was to investigate 28-day mortality after COVID-19 diagnosis in the European kidney replacement therapy population. In addition, we determined the role of patient characteristics, treatment factors, and country on mortality risk using ERA-EDTA Registry data on patients receiving kidney replacement therapy in Europe between February ... Read more >>

Kidney Int. (Kidney international)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Thrombotic microangiopathy: COVID-19 or Hydroxychloroquine?

Nuri Baris Hasbal,

Kidney Int. (Kidney international)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Advertisement

Thrombotic microangiopathy: COVID-19 or Hydroxychloroquine?

Nuri Baris Hasbal,

Kidney Int. (Kidney international)
[2020, :]

Cited: 0 times

View full text PDF listing >>



The sodium/proton exchanger NHA2 regulates blood pressure through a WNK4-NCC dependent pathway in the kidney.

Manuel A Anderegg, Giuseppe Albano, Daniela Hanke, Christine Deisl, Dominik E Uehlinger, Simone Brandt, Rajesh Bhardwaj, Matthias A Hediger, Daniel G Fuster,

NHA2 is a sodium/proton exchanger associated with arterial hypertension in humans, but the role of NHA2 in kidney function and blood pressure homeostasis is currently unknown. Here we show that NHA2 localizes almost exclusively to distal convoluted tubules in the kidney. NHA2 knock-out mice displayed reduced blood pressure, normocalcemic hypocalciuria ... Read more >>

Kidney Int. (Kidney international)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Response to Thrombotic Microangiopathy: COVID-19 or Hydroxychloroquine?

Rimda Wanchoo, Maria Louise Barilla-LaBarca, Kenar D. Jhaveri,

Kidney Int. (Kidney international)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Response to Thrombotic Microangiopathy: COVID-19 or Hydroxychloroquine?

Rimda Wanchoo, Maria Louise Barilla-LaBarca, Kenar D Jhaveri,

Kidney Int. (Kidney international)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Plasma cadmium is associated with increased risk of long-term kidney graft failure.

Camilo G Sotomayor, Dion Groothof, Joppe J Vodegel, Michele F Eisenga, Tim J Knobbe, Jan IJmker, Rosa G M Lammerts, Martin H de Borst, Stefan P Berger, Ilja M Nolte, Ramón Rodrigo, Riemer H J A Slart, Gerjan J Navis, Daan J Touw, Stephan J L Bakker,

The kidney is one of the most sensitive organs to cadmium-induced toxicity, particularly in conditions of long-term oxidative stress. We hypothesized that, in kidney transplant recipients, nephrotoxic exposure to cadmium represents an overlooked hazard for optimal graft function. To test this, we performed a prospective cohort study and included 672 ... Read more >>

Kidney Int. (Kidney international)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Successful Simultaneous Pancreas and Kidney Transplant in a Patient Post-COVID-19 Infection

Neeraj Singh, Srijan Tandukar, Gazi Zibari, Muhammad Saad Naseer, Hosein S. Amiri, Millie Samaniego,

Kidney Int. (Kidney international)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Immune evasion in renal cell carcinoma: biology, clinical translation, future directions.

Xiaoyang Wang, Robert Lopez, Rebecca A Luchtel, Sassan Hafizi, Benjamin Gartrell, Niraj Shenoy,

Targeted therapies and immune checkpoint inhibitors have advanced the treatment landscape of Renal Cell Carcinoma (RCC) over the last decade. While checkpoint inhibitors have demonstrated survival benefit and are currently approved in the front-line and second-line settings, primary and secondary resistance is common. A comprehensive understanding of the mechanisms of ... Read more >>

Kidney Int. (Kidney international)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Successful Simultaneous Pancreas and Kidney Transplant in a Patient Post-COVID-19 Infection.

Neeraj Singh, Srijan Tandukar, Gazi Zibari, Muhammad Saad Naseer, Hosein S Amiri, Millie Samaniego,

Kidney Int. (Kidney international)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Subgroup analysis of the ASPirin in Reducing Events in the Elderly randomized clinical trial suggest aspirin did not improve outcomes in older adults with chronic kidney disease.

Rory Wolfe, James B Wetmore, Robyn L Woods, John J McNeil, Hugh Gallagher, Paul Roderick, Rowan Walker, Mark R Nelson, Christopher M Reid, Raj C Shah, Michael E Ernst, Jessica E Lockery, Andrew M Tonkin, Walter P Abhayaratna, Peter Gibbs, Erica M Wood, Suzanne E Mahady, Jeff D Williamson, Geoffrey A Donnan, Geoffrey C Cloud, Anne M Murray, Kevan R Polkinghorne, ,

The role of aspirin for primary prevention in older adults with chronic kidney disease (CKD) is unclear. Therefore, post hoc analysis of the randomized controlled trial ASPirin in Reducing Events in the Elderly (ASPREE) was undertaken comparing 100 mg of enteric-coated aspirin daily against matching placebo. Participants were community dwelling ... Read more >>

Kidney Int. (Kidney international)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Renin-angiotensin aldosterone inhibitor use at hospital discharge among patients with moderate to severe acute kidney injury and its association with recurrent acute kidney injury and mortality.

Edward D Siew, Sharidan K Parr, Khaled Abdel-Kader, Amy M Perkins, Robert A Greevy, Andrew J Vincz, Jason Denton, Otis D Wilson, Adriana M Hung, T Alp Ikizler, Cassianne Robinson-Cohen, Michael E Matheny,

Recurrent episodes of acute kidney injury (AKI) are common among AKI survivors. Renin-angiotensin aldosterone inhibitors (RAASi) are often indicated for these patients but may increase the risk for recurrent AKI. Here, we examined whether RAASi associates with a higher risk for recurrent AKI and mortality among survivors of moderate to ... Read more >>

Kidney Int. (Kidney international)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Magnetic resonance imaging accurately tracks kidney pathology and heterogeneity in the transition from acute kidney injury to chronic kidney disease.

Jennifer R Charlton, Yanzhe Xu, Teresa Wu, Kim A deRonde, Jillian L Hughes, Shourik Dutta, Gavin T Oxley, Aleksandra Cwiek, Helen P Cathro, Nathan P Charlton, Mark R Conaway, Edwin J Baldelomar, Neda Parvin, Kevin M Bennett,

Acute kidney injury (AKI) increases the risk for chronic kidney disease (CKD). However, there are few tools to detect microstructural changes after AKI. Here, cationic ferritin-enhanced magnetic resonance imaging (CFE-MRI) was applied to examine the heterogeneity of kidney pathology in the transition from AKI to CKD. Adult male mice received ... Read more >>

Kidney Int. (Kidney international)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Mineral bone disease in autosomal dominant polycystic kidney disease.

Berenice Gitomer, Renata Pereira, Isidro B Salusky, Jason W Stoneback, Tamara Isakova, Xuan Cai, Lorien S Dalrymple, Norma Ofsthun, Zhiying You, Harmut H Malluche, Franklin Maddux, Diana George, Vicente Torres, Arlene Chapman, Theodore I Steinman, Myles Wolf, Michel Chonchol,

Mice with disruption of Pkd1 in osteoblasts demonstrate reduced bone mineral density, trabecular bone volume and cortical thickness. To date, the bone phenotype in adult patients with autosomal dominant polycystic kidney disease (ADPKD) with stage I and II chronic kidney disease has not been investigated. To examine this, we characterized ... Read more >>

Kidney Int. (Kidney international)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Sepsis-Associated Acute Kidney Injury: Is COVID-19 different?

John A Kellum, Mitra K Nadim, Lui G Forni,

Kidney Int. (Kidney international)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Sepsis-Associated Acute Kidney Injury: Is COVID-19 different?

John A. Kellum, Mitra K. Nadim, Lui G. Forni,

Kidney Int. (Kidney international)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Cystinuria: clinical practice recommendation.

Aude Servais, Kay Thomas, Luca Dello Strologo, John A Sayer, Soumeya Bekri, Aurelia Bertholet-Thomas, Matthew Bultitude, Giovanna Capolongo, Rimante Cerkauskiene, Michel Daudon, Steeve Doizi, Valentine Gillion, Silvia Gràcia-Garcia, Jan Halbritter, Laurence Heidet, Marleen van den Heijkant, Sandrine Lemoine, Bertrand Knebelmann, Francesco Emma, Elena Levtchenko, ,

Cystinuria (OMIM 220100) is an autosomal recessive hereditary disorder in which high urinary cystine excretion leads to formation of cystine stones due to its low solubility at normal urinary pH. We developed clinical practice recommendation for diagnosis, surgical and medical treatment, and follow up of cystinuria patients. Elaboration of these ... Read more >>

Kidney Int. (Kidney international)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Human kidney organoids produce functional renin.

Anusha S Shankar, Zhaoyu Du, Hector Tejeda Mora, Thierry P P van den Bosch, Sander S Korevaar, Ingrid M Van den Berg-Garrelds, Eric Bindels, Carmen Lopez-Iglesias, Marian Clahsen-van Groningen, Joost Gribnau, Carla C Baan, A H Jan Danser, Ewout J Hoorn, Martin J Hoogduijn,

Renin production by the kidney is of vital importance for salt, volume, and blood pressure homeostasis. The lack of human models hampers investigation into the regulation of renin and its relevance for kidney physiology. To develop such a model, we used human induced pluripotent stem cell derived kidney organoids to ... Read more >>

Kidney Int. (Kidney international)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Proximal tubular dysfunction in patients with COVID-19: what have we learnt so far?

Fabian Braun, Tobias B Huber, Victor G Puelles,

Recent studies have reported a variety of urine abnormalities in patients hospitalized due to SARS-CoV-2 infection. In a single center study from Belgium, Werion et al., now present a concise investigation of tubular dysfunction in COVID-19 patients identifying potential risk factors for increased disease severity. These data complement current evidence ... Read more >>

Kidney Int. (Kidney international)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Prediction modelling - Part 2 - Using machine learning strategies to improve transplantation outcomes.

Craig Peter Coorey, Ankit Sharma, Samuel Mueller, Jean Yang,

Kidney transplant recipients and transplant physicians face important clinical questions where machine learning methods may help improve the decision-making process. This mini-review explores potential applications of machine learning methods to key stages of a kidney transplant recipient's journey, from initial waitlisting and donor selection, to personalization of immunosuppression and prediction ... Read more >>

Kidney Int. (Kidney international)
[2020, :]

Cited: 0 times

View full text PDF listing >>



The phosphoinositide 3-kinase inhibitor alpelisib restores actin organization and improves proximal tubule dysfunction in vitro and in a mouse model of Lowe syndrome and Dent disease.

Marine Berquez, Jonathan R Gadsby, Beatrice Paola Festa, Richard Butler, Stephen P Jackson, Valeria Berno, Alessandro Luciani, Olivier Devuyst, Jennifer L Gallop,

Loss-of-function mutations in the OCRL gene, which encodes the phosphatidylinositol [PI] 4,5-bisphosphate [PI(4,5)P2] 5-phosphatase OCRL, cause defective endocytosis and proximal tubule dysfunction in Lowe syndrome and Dent disease 2. The defect is due to increased levels of PI(4,5)P2 and aberrant actin polymerization, blocking endosomal trafficking. PI 3-phosphate [PI(3)P] has been ... Read more >>

Kidney Int. (Kidney international)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Time-dependent lymphocyte count after transplantation is associated with higher risk of graft failure and death.

Amaury Dujardin, Marine Lorent, Yohann Foucher, Christophe Legendre, Clarisse Kerleau, Sophie Brouard, Magali Giral, ,

The transplantation field requires the identification of specific risk factors associated with the level of immunosuppression. Here, our aim was to analyze the association between the number of circulating lymphocytes, monitored routinely by complete blood cell counts during outpatient visits, and patient and graft survival. In total, 2,999 kidney or ... Read more >>

Kidney Int. (Kidney international)
[2020, :]

Cited: 0 times

View full text PDF listing >>



HLA-D and PLA2R1 risk alleles associate with recurrent primary membranous nephropathy in kidney transplant recipients.

Lena Berchtold, Eric Letouzé, Mariam Priya Alexander, Guillaume Canaud, Anne-Els van de Logt, Patrick Hamilton, Christiane Mousson, Vincent Vuiblet, Ann M Moyer, Sylvain Guibert, Petra Mrázová, Charlène Levi, Valérie Dubois, Josep Maria Cruzado, Armando Torres, Manish J Gandhi, Nadhir Yousfi, Vladimir Tesar, Ondrej Viklický, Maryvonne Hourmant, Bruno Moulin, Philippe Rieu, Gabriel Choukroun, Christophe Legendre, Jack Wetzels, Paul Brenchley, José Aurelio Ballarín Castan, Hanna Debiec, Pierre Ronco,

Recurrence of primary membranous nephropathy after transplantation occurs in up to 44% of patients and is driven by PLA2R antibody. Here, we asked whether genetic determinants could improve risk prediction. First, we sequenced PLA2R1 and HLA-D loci in 248 patients with primary membranous nephropathy and identified two independent single nucleotide ... Read more >>

Kidney Int. (Kidney international)
[2020, :]

Cited: 0 times

View full text PDF listing >>



The Case | A patient with recurrent ventricular fibrillation and renal failure.

Maria López-Andreu, M Dolores Navarro Cabello, Rafael Sánchez-Sánchez, J Mariano Rodríguez-Portillo, Sagrario Soriano Cabrera,

Kidney Int. (Kidney international)
[2020, 98(3):795-796]

Cited: 0 times

View full text PDF listing >>



The authors reply.

David H Ellison, Biff F Palmer,

Kidney Int. (Kidney international)
[2020, 98(3):785]

Cited: 0 times

View full text PDF listing >>



Advertisement

Disclaimer
1.0118 s