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Cutaneous metastasis of renal pelvic urothelial carcinoma mimicking cutaneous angiosarcoma.

Ruriko Endo, Yoshiyuki Nakamura, Sae Inoue, Yasuhiro Fujisawa,

Jpn J Clin Oncol (Japanese journal of clinical oncology)
[2021, :]

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The significance of biopsy scar excision at the time of skin- or nipple-sparing mastectomy with immediate breast reconstruction.

Yuri Ozaki, Akiyo Yoshimura, Masataka Sawaki, Masaya Hattori, Haruru Kotani, Yayoi Adachi, Ayumi Kataoka, Kayoko Sugino, Nanae Horisawa, Yuka Endo, Kazuki Nozawa, Shoko Sakamoto, Daiki Takatsuka, Seiko Okumura, Yoko Maruyama, Hiroji Iwata,

<h4>Background</h4>Neoplastic seeding (NS) can occur after tissue biopsy, which is a clinical issue especially in mastectomy with immediate reconstruction. This is because postoperative radiation is not usually given and local recurrence of preserved skin flap may increase. The purpose of this study is to investigate the importance of preoperative evaluation ... Read more >>

Jpn J Clin Oncol (Japanese journal of clinical oncology)
[2021, :]

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Overexpression of Janus kinase 2 protein in extramammary Paget's disease.

Saki Otsuka-Maeda, Myangat Tselmeg Mijiddorj, Ikko Kajihara, Ryoko Sakamoto, Saori Yamada-Kanazawa, Hisashi Kanemaru, Yuki Nishimura, Soichiro Sawamura, Katsunari Makino, Jun Aoi, Takamitsu Makino, Shinichi Masuguchi, Satoshi Fukushima, Hironobu Ihn,

Extramammary Paget's disease is a rare malignant tumor of the skin that occurs primarily in the genitocrural region. Although the prognosis of extramammary Paget's disease with distant metastasis is poor, an effective therapy has not been established. Because Janus kinase 2 has attracted attention as a therapeutic target in several ... Read more >>

Jpn J Clin Oncol (Japanese journal of clinical oncology)
[2021, :]

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Primary sacral lymphoma with multiple bone involvement evaluated using 18F-FDG PET/CT.

Aiqi Shi, Xianwang Liu, Jianlin Wang, Jiangyan Liu,

Jpn J Clin Oncol (Japanese journal of clinical oncology)
[2021, :]

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Oestrogen receptor alpha in papillary thyroid carcinoma: association with clinical features and BRAFV600E mutation.

Shiyang Liu, Bo Jiao, Shuyu Li, Lu Zhao, Weihong Zheng, Kun Wang, Jing Xu, Yao Tian, Chenguang Liu, Zhengwei Gui, Lin Zhang,

<h4>Background</h4>Papillary thyroid cancer cells can express oestrogen receptor alpha, which is encoded by the ESR1 gene and may bind to oestrogen to induce the occurrence and development of papillary thyroid cancer. The BRAFV600E mutation is also an important biomarker for the occurrence and progression of papillary thyroid cancer. However, the ... Read more >>

Jpn J Clin Oncol (Japanese journal of clinical oncology)
[2021, :]

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Erratum to: Response to Dr Shikata's letter: 'Secondhand smoke exposure and risk of lung cancer in Japan: a systematic review and meta-analysis of epidemiologic studies'.

Megumi Hori, Hirokazu Tanaka, Eiko Saito, Kenji Wakai, Kota Katanoda,

Jpn J Clin Oncol (Japanese journal of clinical oncology)
[2021, :]

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Screening of chronic radiation proctitis and colorectal cancer using periodic total colonoscopy after external beam radiation therapy for prostate cancer.

Yuki Nakamura, Takahiko Soma, Keita Izumi, Yasuyuki Sakai, Hiroki Ushijima, Shigehiro Kudo, Yoshihiro Saito, Yukio Kageyama,

<h4>Objective</h4>To investigate the incidence of colorectal cancer and chronic radiation proctitis after prostate radiotherapy using periodic total colonoscopy screening.<h4>Methods</h4>From February 2013 to January 2018, 270 patients who underwent external beam radiation therapy for prostate cancer were advised to receive periodic total colonoscopy screening annually. We evaluated the incidence and characteristics ... Read more >>

Jpn J Clin Oncol (Japanese journal of clinical oncology)
[2021, :]

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Effects of Helicobacter pylori eradication on gastric cancer incidence in the Japanese population: a systematic evidence review.

Yingsong Lin, Sayo Kawai, Tae Sasakabe, Chisato Nagata, Mariko Naito, Keitaro Tanaka, Yumi Sugawara, Tetsuya Mizoue, Norie Sawada, Keitaro Matsuo, Tetsuhisa Kitamura, Mai Utada, Hidemi Ito, Taichi Shimazu, Shogo Kikuchi, Manami Inoue, ,

<h4>Background</h4>In Japan, there are ongoing efforts to shift the gastric cancer prevention and control policy priorities from barium-based screening to Helicobacter pylori (H. pylori)-oriented primary prevention. A comprehensive summary of the evidence regarding the effects of H. pylori eradication on the risk of gastric cancer could inform policy decisions.<h4>Methods</h4>We conducted ... Read more >>

Jpn J Clin Oncol (Japanese journal of clinical oncology)
[2021, :]

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Patterns of immune infiltration in gastric cancer and their clinical significance.

Yin Jin, Liping Tao, Shuqing Jin, Weiyang Cai,

<h4>Objective</h4>The malignant phenotypes of cancer are defined not only by its intrinsic tumor cells but also by the tumor-infiltrating immune cells activated and recruited to the cancer microenvironment. However, a comprehensive introduction of gastric cancer immune cell infiltration has not been identified so far.<h4>Methods</h4>In this study, we comprehensively analyzed the ... Read more >>

Jpn J Clin Oncol (Japanese journal of clinical oncology)
[2021, :]

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Feasibility of next-generation sequencing (Oncomine™ DX Target Test) for the screening of oncogenic mutations in advanced non-small-cell lung cancer patients.

Yuki Takeyasu, Tatsuya Yoshida, Noriko Motoi, Takashi Teishikata, Midori Tanaka, Yuji Matsumoto, Yuki Shinno, Yusuke Okuma, Yasushi Goto, Hidehito Horinouchi, Hiroki Kakishima, Takaaki Tsuchida, Noboru Yamamoto, Yuichiro Ohe, Yasushi Yatabe,

<h4>Background</h4>The Oncomine™ Dx Target Test based on next-generation sequencing has been approved for the screening of oncogenic mutations in advanced non-small-cell lung cancer patients.<h4>Methods</h4>We assessed the tissue sample factors that affect the success rate of Oncomine™ Dx Target Test companion diagnostics and the feasibility of using biopsy specimens for Oncomine™ ... Read more >>

Jpn J Clin Oncol (Japanese journal of clinical oncology)
[2021, :]

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Transarterial management of advance lung cancer.

Shinichi Hori, Tatsuya Nakamura, Norifumi Kennoki, Ikuo Dejima, Atsushi Hori,

Previous reports on transarterial treatment for lung cancer were reviewed. The bronchial arterial infusion therapy has a long history since 1964. Better local control with less doses of anti-neoplastic agents was warranted by trying transarterial administration to lung and mediastinal tumors. It is reported that both primary and metastatic tumors ... Read more >>

Jpn J Clin Oncol (Japanese journal of clinical oncology)
[2021, :]

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Novel hybrid endoscopy-assisted larynx-preserving esophagectomy for cervical esophageal cancer (with video).

Seiichiro Abe, Junya Oguma, Satoru Nonaka, Haruhisa Suzuki, Shigetaka Yoshinaga, Ichiro Oda, Yutaka Saito, Hiroyuki Daiko,

Hybrid endoscopy-assisted larynx-preserving esophagectomy is developed for cervical esophageal squamous cell carcinoma encroaching or extending above the upper esophageal sphincter. First, a cervical incision was surgically performed followed by cervical lymph node dissection. Second, the margin of cervical esophageal squamous cell carcinoma was endoscopically identified with iodine staining and marked ... Read more >>

Jpn J Clin Oncol (Japanese journal of clinical oncology)
[2021, :]

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Histopathological atlas of desmoplastic reaction characterization in colorectal cancer.

Hideki Ueno, Yoshiki Kajiwara, Yoich Ajioka, Tamotsu Sugai, Shigeki Sekine, Megumi Ishiguro, Atsuo Takashima, Yukihide Kanemitsu,

Emergent scientific evidence indicates the central role of cancer-associated fibroblasts in determining whether the microenvironment of cancer works as friend or foe of the host; however, there is no unified histological evaluation framework of fibrotic stroma in colorectal cancers. Myxoid stroma and keloid-like collagen are site-specific histopathological features generated by ... Read more >>

Jpn J Clin Oncol (Japanese journal of clinical oncology)
[2021, :]

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Coverage of the hospital-based cancer registries and the designated cancer care hospitals in Japan.

Ayako Okuyama, Yoichiro Tsukada, Takahiro Higashi,

<h4>Background</h4>Hospital-based cancer registries were developed to describe and improve clinical care for cancer patients. We described the hospital-based cancer registry coverage as a reference for the users, including researchers, policymakers and clinicians.<h4>Methods</h4>The hospital-based cancer registry coverage was defined as the proportion of new cases registered in the hospital-based cancer registry ... Read more >>

Jpn J Clin Oncol (Japanese journal of clinical oncology)
[2021, :]

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Post-operative small pelvic intensity-modulated radiation therapy for early-stage cervical cancer with intermediate-risk factors: efficacy and toxicity.

Guangyu Zhang, Fangfang He, Li Miao, Haijian Wu, Youzhong Zhang, Chunli Fu,

<h4>Objective</h4>The aim of the present study was to retrospectively evaluate the toxicity and efficacy of post-operative small pelvic intensity-modulated radiotherapy in early-stage cervical cancer patients with intermediate-risk factors.<h4>Methods</h4>Between 2012 and 2016, 151 patients who had cervical cancer (International Federation of Gynecology and Obstetrics stage I-IIA) with intermediate-risk factors were treated ... Read more >>

Jpn J Clin Oncol (Japanese journal of clinical oncology)
[2021, :]

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Septic phlebitis of the liver presenting as fever of unknown origin detected by FDG PET/CT.

JingXing Xiao, Dong Wang,

Jpn J Clin Oncol (Japanese journal of clinical oncology)
[2021, :]

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Sarcopenia and obesity in long-term survivors of childhood leukemia/lymphoma: a report from a single institution.

Hideki Nakayama, Maiko Noguchi, Reiji Fukano, Tamaki Ueda, Shizu Taguchi, Kenichi Yoshimaru, Michiko Namie, Mototsugu Shimokawa, Jun Okamura,

<h4>Background</h4>The incidence and background factors of sarcopenia and obesity in long-term survivors of childhood leukemia/lymphoma were not clear in Japan.<h4>Methods</h4>Between August 2018 and September 2019, we recruited adults aged ≥18 years who had childhood leukemia/lymphoma. Blood sampling, body composition measurement by bioelectrical impedance analysis and grip strength test were performed.<h4>Results</h4>Among ... Read more >>

Jpn J Clin Oncol (Japanese journal of clinical oncology)
[2021, :]

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Is perioperative chemotherapy recommended in childhood and adolescent patients with synovial sarcoma? A systematic review.

Tomoki Nakamura, Yuya Saito, Kunihiko Tsuchiya, Mitsuru Miyachi, Shintaro Iwata, Akihiro Sudo, Akira Kawai,

<h4>Objective</h4>Synovial sarcoma is the most common soft tissue sarcomas among childhood and adolescents, accounting for 8-10% of all soft tissue sarcoma. Synovial sarcoma is considered a relatively chemosensitive tumor compared with other soft tissue sarcomas. However, the role of perioperative chemotherapy in synovial sarcoma remains controversial. The purpose of this ... Read more >>

Jpn J Clin Oncol (Japanese journal of clinical oncology)
[2021, :]

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A novel osimertinib-resistant human lung adenocarcinoma cell line harbouring mutant EGFR and activated IGF1R.

Go Makimoto, Kiichiro Ninomiya, Toshio Kubo, Ryota Sunami, Yuka Kato, Eiki Ichihara, Kadoaki Ohashi, Kammei Rai, Katsuyuki Hotta, Masahiro Tabata, Yoshinobu Maeda, Katsuyuki Kiura,

<h4>Objective</h4>A third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI), osimertinib, is the standard treatment for patients with non-small cell lung cancer harbouring mutant EGFR. Unfortunately, these patients inevitably acquire resistance to EGFR-TKI therapies, including osimertinib. However, the mechanism associated with this resistance remains unclear.<h4>Methods</h4>A 63-year-old Japanese female with ... Read more >>

Jpn J Clin Oncol (Japanese journal of clinical oncology)
[2021, :]

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Histiocytic sarcoma with brainstem and spinal canal involvement detected by [18F]-FDG PET/CT.

Yiraldine Herrera-Martínez, Paula Fernández-Rodríguez, Carmen María Del Prado Alba, Irene Acevedo-Bañez,

Jpn J Clin Oncol (Japanese journal of clinical oncology)
[2021, 51(5):844-845]

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Clinical significance of comprehensive genomic profiling tests covered by public insurance in patients with advanced solid cancers in Hokkaido, Japan.

Junko Kikuchi, Yoshihito Ohhara, Kohichi Takada, Hiroki Tanabe, Kazuteru Hatanaka, Toraji Amano, Kanako C Hatanaka, Yutaka Hatanaka, Takashi Mitamura, Momoko Kato, Yuka Shibata, Ichiro Yabe, Akira Endoh, Yoshito Komatsu, Yoshihiro Matsuno, Minako Sugiyama, Atsushi Manabe, Akihiro Sakurai, Masato Takahashi, Hirohito Naruse, Yoshihiro Torimoto, Hirotoshi Dosaka-Akita, Ichiro Kinoshita,

<h4>Background</h4>Comprehensive cancer genomic profiling has been used recently for patients with advanced solid cancers. Two cancer genomic profiling tests for patients with no standard treatment are covered by Japanese public health insurance since June 2019.<h4>Methods</h4>We prospectively analyzed data of 189 patients with solid cancers who underwent either of the two-cancer ... Read more >>

Jpn J Clin Oncol (Japanese journal of clinical oncology)
[2021, 51(5):753-761]

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Clinical approach to re-irradiation for recurrent diffuse intrinsic pontine glioma.

Rahul Krishnatry, Jifmi Jose Manjali, Girish Chinnaswamy, Abhishek Chatterjee, Jayant Sastri Goda, Amit Janu, Arpita Sahu, Rakesh Jalali, Tejpal Gupta,

<h4>Background</h4>We present our institutional approach for re-irradiation in diffuse intrinsic pontine glioma and their outcomes.<h4>Methods</h4>Consecutive patients of recurrent diffuse intrinsic pontine glioma treated with re-irradiation (January 2015-September 2019) were reviewed retrospectively to describe the clinical-response-based approach followed for the dose and volume decision. Outcomes were defined with clinical and steroid ... Read more >>

Jpn J Clin Oncol (Japanese journal of clinical oncology)
[2021, 51(5):762-768]

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Medical costs of Japanese lung cancer patients during end-of-life care.

Nobuyasu Awano, Takehiro Izumo, Minoru Inomata, Naoyuki Kuse, Mari Tone, Kohei Takada, Yutaka Muto, Kazushi Fujimoto, Hitomi Kimura, Shingo Miyamoto, Ataru Igarashi, Hideo Kunitoh,

<h4>Objective</h4>The medical costs associated with cancer treatment have increased rapidly in Japan; however, little data exist on actual costs, especially for end-of-life care. Therefore, this study aimed to examine the medical costs of lung cancer patients during the last 3 months before death and to compare the costs with those ... Read more >>

Jpn J Clin Oncol (Japanese journal of clinical oncology)
[2021, 51(5):769-777]

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Response to the Dr Shikata's letter: 'Secondhand smoke exposure and risk of lung cancer in Japan: a systematic review and meta-analysis of epidemiologic studies'.

Megumi Hori, Hirokazu Tanaka, Eiko Saito, Kenji Wakai, Kota Katanoda,

Jpn J Clin Oncol (Japanese journal of clinical oncology)
[2021, 51(4):661]

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Therapeutic benefit of lymphadenectomy for older patients with urothelial carcinoma of the upper urinary tract: a propensity score matching study.

Yudai Ishiyama, Tsunenori Kondo, Satoshi Kubota, Katsunori Shimada, Kazuhiko Yoshida, Toshio Takagi, Junpei Iizuka, Kazunari Tanabe,

<h4>Objectives</h4>Regional lymphadenectomy for urothelial carcinoma of the upper urinary tract is sometimes avoided in older patients to reduce surgical burden. We aimed to evaluate the therapeutic impact of lymphadenectomy in older patients undergoing curative therapy for upper urinary tract urothelial carcinoma.<h4>Methods</h4>The patients with urothelial carcinoma of the upper urinary tract ... Read more >>

Jpn J Clin Oncol (Japanese journal of clinical oncology)
[2021, 51(5):802-809]

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