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Clinical recurrences of COVID-19 symptoms after recovery: viral relapse, reinfection or inflammatory rebound?

Dominique Batisse, Nicolas Benech, Elisabeth Botelho-Nevers, Kevin Bouiller, Rocco Collarino, Anne Conrad, Laure Gallay, Francois Goehringer, Marie Gousseff, Dr Cédric Joseph, Adrien Lemaignen, François-Xavier Lescure, Bruno Levy, Matthieu Mahevas, Pauline Penot, Bruno Pozzetto, Dominique Salmon, Dorsaf SLAMA, Nicolas Vignier, Benjamin Wyplosz,

For the first 3 months of COVID-19 pandemic, COVID-19 was expected to be an immunizing non-relapsing disease. We report a national case series of 11 virologically-confirmed COVID-19 patients having experienced a second clinically- and virologically-confirmed acute COVID-19 episode. According to the clinical history, we discuss either re-infection or reactivation hypothesis. ... Read more >>

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COVID-19 and TB co-infection - 'Finishing touch'' in perfect recipe to 'severity’ or ‘death'.

Dr. Rohit Kumar, Dr. Bisakh Bhattacharya, Dr. Vedprakash Meena, Dr. Manish Soneja, Dr. Naveet Wig,

J. Infect. (The Journal of Infection)
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SARS-CoV-2 Detection, Viral Load and Infectivity over the Course of an Infection: SARS-CoV-2 Detection, Viral Load and Infectivity.

Kieran A. Walsh, Karen Jordan, Barbara Clyne, Daniela Rohde, Linda Drummond, Paula Byrne, Susan Ahern, Paul G. Carty, Kirsty K. O'Brien, Eamon O'Murchu, Michelle O'Neill, Susan M. Smith, Máirín Ryan, Patricia Harrington,

ObjectivesTo summarise the evidence on the detection pattern and viral load of SARS-CoV-2 over the course of an infection (including any asymptomatic or pre-symptomatic phase), and the duration of infectivity.MethodsA systematic literature search was undertaken in PubMed, Europe PubMed Central and EMBASE from 30 December 2019 to 12 May 2020.ResultsWe ... Read more >>

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Snapshot PCR Surveillance for SARS-CoV-2 in Hospital Staff in England.

Colin Brown, Kathryn Clare, Meera Chand, Julie Andrews, Cressida Auckland, Sarah Beshir, Saher Choudhry, Kerrie Davies, Jane Freeman, Andrew Gallini, Rachel Moores, Trupti Patel, Gosia Poznalska, Alison Rodger, Stella Roberts, Christopher Rooney, Mark Wilcox, Simon Warren, Joanna Ellis, Robin Gopal, Jake Dunning, Maria Zambon, Susan Hopkins,

BackgroundSignificant nosocomial transmission of SARS-CoV-2 has been demonstrated. Understanding the prevalence of SARS-CoV-2 carriage amongst HCWs at work is necessary to inform the development of HCW screening programmes to control nosocomial spread.MethodsCross-sectional ‘snapshot’ survey from April-May 2020; HCWs recruited from six UK hospitals. Participants self-completed a health questionnaire and underwent ... Read more >>

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Investigation of a family outbreak of COVID-19 using systematic rapid diagnostic tests raises new questions about transmission.

Thierry Prazuck, Susanna Giaché, Camelia Gubavu, Mathilda Colin, Vincent Rzepecki, Aymeric Sève, Gilles Pialoux, Laurent Hocqueloux,

J. Infect. (The Journal of Infection)
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Snapshot PCR Surveillance for SARS-CoV-2 in Hospital Staff in England.

Colin Brown, Kathryn Clare, Meera Chand, Julie Andrews, Cressida Auckland, Sarah Beshir, Saher Choudhry, Kerrie Davies, Jane Freeman, Andrew Gallini, Rachel Moores, Trupti Patel, Gosia Poznalska, Alison Rodger, Stella Roberts, Christopher Rooney, Mark Wilcox, Simon Warren, Joanna Ellis, Robin Gopal, Jake Dunning, Maria Zambon, Susan Hopkins,

Significant nosocomial transmission of SARS-CoV-2 has been demonstrated. Understanding the prevalence of SARS-CoV-2 carriage amongst HCWs at work is necessary to inform the development of HCW screening programmes to control nosocomial spread. Cross-sectional 'snapshot' survey from April-May 2020; HCWs recruited from six UK hospitals. Participants self-completed a health questionnaire and ... Read more >>

J. Infect. (The Journal of infection)
[2020, :]

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The usefulness of quantitative interferon-gamma releasing assay response for predicting active tuberculosis in kidney transplant recipients: a quasi-experimental study.

Haein Kim, Sung-Han Kim, Joo Hee Jung, Min Jae Kim, Hyosang Kim, Sung Shin, Yong Pil Chong, Young-Hoon Kim, Sang-Oh Lee, Sang-Ho Choi, Yang Soo Kim, Jun Hee Woo, Su-Kil Park, Duck Jong Han,

OBJECTIVES:We evaluated the effectiveness of IGRA-based isoniazid (INH) treatment with the diagnostic value of quantitative IGRA titer for post-transplant tuberculosis (TB) in kidney transplant (KT) recipients. METHODS:All adult KT recipients were enrolled from January 2014 to December 2017. The development of TB after KT was observed, stratified by quantitative IGRA ... Read more >>

J. Infect. (The Journal of infection)
[2020, :]

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SARS-CoV-2 Detection, Viral Load and Infectivity over the Course of an Infection: SARS-CoV-2 Detection, Viral Load and Infectivity.

Kieran A Walsh, Karen Jordan, Barbara Clyne, Daniela Rohde, Linda Drummond, Paula Byrne, Susan Ahern, Paul G Carty, Kirsty K O'Brien, Eamon O'Murchu, Michelle O'Neill, Susan M Smith, Máirín Ryan, Patricia Harrington,

To summarise the evidence on the detection pattern and viral load of SARS-CoV-2 over the course of an infection (including any asymptomatic or pre-symptomatic phase), and the duration of infectivity. A systematic literature search was undertaken in PubMed, Europe PubMed Central and EMBASE from 30 December 2019 to 12 May ... Read more >>

J. Infect. (The Journal of infection)
[2020, :]

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REPLY TO: Interleukin-17: a potential therapeutic target in COVID-19.

Stefano Piaserico, Alberto Meneguzzo, Francesco Messina,

J. Infect. (The Journal of infection)
[2020, :]

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COVID-19 and TB co-infection - 'Finishing touch'' in perfect recipe to 'severity' or 'death'.

Dr Rohit Kumar, Dr Bisakh Bhattacharya, Dr Vedprakash Meena, Dr Manish Soneja, Dr Naveet Wig,

J. Infect. (The Journal of infection)
[2020, :]

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The role of volatile organic compounds as predictors of treatment response in drug susceptible TB patients: an initial proof of concept study.

Rosarito Coronel Teixeira, Sandra Gonzalez, Myrian Román, Nilda Romero, Jan Bart Yntema, Domingo Pérez Bejarano, Cecile Magis-Escurra,

J. Infect. (The Journal of infection)
[2020, :]

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REPLY TO: Interleukin-17: a potential therapeutic target in COVID-19.

Stefano Piaserico, Alberto Meneguzzo, Francesco Messina,

J. Infect. (The Journal of Infection)
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Distinct and early increase in circulating MMP-9 in COVID-19 patients with respiratory failure.

Ueland T, Holter Jc, Holten Ar, Müller Ke, Lind A, Bekken Gk, Dudmann S, Aukrust P, Dyrhol-Riise Am, Heggelund L,

J. Infect. (The Journal of Infection)
[2020, :]

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Cardiac injury and mortality in COVID-19: a reappraisal.

Mislav Vrsalovic, Ana Vrsalovic Presecki,

J. Infect. (The Journal of Infection)
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The role of healthcare staff COVID-19 screening in infection prevention & control.

David Moynan, Maura Cagney, Aoife Ni Dhuthaigh, Margaret Foley, Aisling Salter, Niamh Reidy, Paul Reidy, Eoghan de Barra, Fidelma Fitzpatrick,

J. Infect. (The Journal of Infection)
[2020, :]

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Retrospective, multicenter study on the impact of baricitinib in COVID-19 moderate pneumonia.

Fabrizio Cantini, Laura Niccoli, Carlotta Nannini, Daniela Matarrese, Massimo Edoardo Di Natale, Pamela Lotti, Donatella Aquilini, Giancarlo Landini, Barbara Cimolato, Massimo Antonio Di Pietro, Michele Trezzi, Paolo Stobbione, Gabriele Frausini, Assunta Navarra, Emanuele Nicastri, Giovanni Sotgiu, Delia Goletti,

J. Infect. (The Journal of Infection)
[2020, :]

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Improving antibiotic stewardship in COVID-19: bacterial co-infection is less common than with influenza.

Jonathan Youngs, Duncan Wyncoll, Philip Hopkins, Amber Arnold, Jonathan Ball, Tihana Bicanic,

J. Infect. (The Journal of Infection)
[2020, :]

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A tale of two cities: a comparison of Hong Kong and Singapore's early strategies for the Coronavirus Disease 2019 (COVID-19).

Michelle Lee Zhi Qing De Deyn, Qin Xiang Ng, Wayren Loke, Wee Song Yeo,

J. Infect. (The Journal of Infection)
[2020, :]

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Cardiac injury and mortality in COVID-19: a reappraisal.

Mislav Vrsalovic, Ana Vrsalovic Presecki,

J. Infect. (The Journal of infection)
[2020, :]

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The Global Meningitis Genome Partnership.

Elizabeth Rodgers, Stephen D Bentley, Ray Borrow, Holly B Bratcher, Sylvain Brisse, Angela B Brueggemann, Dominique A Caugant, Jamie Findlow, LeAnne Fox, Linda Glennie, Lee H Harrison, Odile B Harrison, Robert S Heyderman, Melissa Jansen van Rensburg, Keith A Jolley, Brenda Kwambana-Adams, Shamez Ladhani, Marc LaForce, Michael Levin, Jay Lucidarme, Neil MacAlasdair, Jenny Maclennan, Martin C J Maiden, Laura Maynard-Smith, Alessandro Muzzi, Philipp Oster, Charlene M C Rodrigues, Olivier Ronveauxq Laura Serino, Vinny Smith, Arie van der Ende, Julio Vázquez, Xin Wang, Saber Yezli, James M Stuart,

Genomic surveillance of bacterial meningitis pathogens is essential for effective disease control globally, enabling identification of emerging and expanding strains and consequent public health interventions. While there has been a rise in the use of whole genome sequencing, this has been driven predominately by a subset of countries with adequate ... Read more >>

J. Infect. (The Journal of infection)
[2020, :]

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OUTBREAK OF COVID-19 IN A NURSING HOME IN MADRID.

Emilio Bouza, María Jesús Pérez-Granda, Pilar Escribano, Rocío Fernández-Del Rey, Ignacio Pastor, Zaira Moure, Pilar Catalán, Roberto Alonso, Patricia Muñoz, Jesús Guinea, ,

J. Infect. (The Journal of Infection)
[2020, :]

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Investigation of a family outbreak of COVID-19 using systematic rapid diagnostic tests raises new questions about transmission.

Thierry Prazuck, Susanna Giaché, Camelia Gubavu, Mathilda Colin, Vincent Rzepecki, Aymeric Sève, Gilles Pialoux, Laurent Hocqueloux,

J. Infect. (The Journal of infection)
[2020, :]

Cited: 0 times

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A Large Scale Waterborne Campylobacteriosis Outbreak, Havelock North, New Zealand.

Brent J Gilpin, Tiffany Walker, Shevaun Paine, Jill Sherwood, Graham Mackereth, Tim Wood, Tammy Hambling, Chris Hewison, Angela Brounts, Maurice Wilson, Paula Scholes, Beth Robson, Susan Lin, Angela Cornelius, Lucia Rivas, David T S Hayman, Nigel P French, Ji Zhang, David A Wilkinson, Anne C Midwinter, Patrick J Biggs, Anita Jagroop, Rachel Eyre, Michael G Baker, Nicholas Jones,

BACKGROUND:We describe the investigation of a Campylobacter outbreak linked to contamination of an untreated, groundwater derived drinking water supply. METHODS:We analysed epidemiological data collected from clinician-confirmed diarrheal cases and estimated the total burden of Havelock North cases using an age-adjusted cross-sectional telephone survey. Campylobacter isolates from case fecal specimens, groundwater ... Read more >>

J. Infect. (The Journal of infection)
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Molecular identification of Cryptococcus gattii from cerebrospinal fluid using single-cell sequencing: a case study.

Min Chen, Nan Hong, Shan Hu, Peng Wang, HongZhi Guan, Meng Xiao, Xinlin Zhu, Abdullah M S Al-Hatmi, Zhe Zhou, Lei Gao, Teun Boekhout, Jianping Xu, Yingchun Xu, Wanqing Liao, Ying Yang,

A 31-year-old man presented with cryptococcal meningitis (CM) without typical clinical characteristics, but with abnormal walking, difficult leg lifting and frequent falling. He was admitted to a hospital in Beijing for two months and then transferred to Peking Union Medical College Hospital. After multiple tests failed to identify the pathogen, ... Read more >>

J. Infect. (The Journal of Infection)
[2020, :]

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Clinical feedback from experience with COVID-19: Specific considerations for extracorporeal membrane oxygenation.

Antonio Fiore, Quentin de Roux, Nejla Daami, Simon Clariot, Thierry Folliguet, Fabio Silvio Taccone, Nicolas Mongardon,

J. Infect. (The Journal of Infection)
[2020, :]

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