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The curious phenomenon of early cardiac allograft rejection with hepatitis C‒infected donor heart transplants.

Ann E Woolley, Steve K Singh,

J. Heart Lung Transplant. (The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation)
[2020, :]

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Durable mechanical circulatory support across the Asia-Pacific region.

Cumaraswamy Sivathasan, Christopher Hayward, Paul Jansz, Amul Kumar Sibal, ChenChen, Ho Ka Lai Cally, Komarakshi Rajagopalan Balakrishnan, Yang Hyun Cho, Mohd Nazeri Nordin, Joseph B Barril, Feras Khaliel, Mandeep R Mehra,

J. Heart Lung Transplant. (The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation)
[2020, :]

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Durable Mechanical Circulatory Support Across the Asia Pacific Region

Cumaraswamy Sivathasan, Christopher Hayward, Paul Jansz, Amul Kumar Sibal, Chen Chen, Ho Ka Lai Cally, Komarakshi Rajagopalan Balakrishnan, Yang Hyun Cho, Mohd.Nazeri Nordin, Joseph B. Barril, Feras Khaliel, Mandeep R. Mehra,

J. Heart Lung Transplant. (The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation)
[2020, :]

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Cocaine use in organ donors and long-term outcome after heart transplantation: An International Society for Heart and Lung Transplantation registry analysis.

Jefferson L Vieira, Wida S Cherikh, Kelsi Lindblad, Josef Stehlik, Mandeep R Mehra,

BACKGROUND:Cardiac allografts from donors with a history of cocaine use (DHCU) are often discarded owing to concerns regarding organ quality. We investigated long-term outcomes of de novo adult heart transplantation (HTx) using DHCU. METHODS:Using the International Society for Heart and Lung Transplantation Thoracic Organ Transplant Registry, we identified 24,430 adult ... Read more >>

J. Heart Lung Transplant. (The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation)
[2020, :]

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Use of sacubitril-valsartan in blood pressure control with left ventricular assist devices.

David Dobarro, Carles Diez-López, David Couto-Mallón, Javier Castrodeza, Manuel Gómez-Bueno, Javier Tobar, Scott McKenzie, Antonio Gonçalves, Maria Melendo-Viu, Carlos Ortiz, Jose González-Costello,

J. Heart Lung Transplant. (The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation)
[2020, :]

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Hemodynamics and risk assessment 2 years after the initiation of upfront ambrisentan‒tadalafil in pulmonary arterial hypertension.

Michele D'Alto, Roberto Badagliacca, Francesco Lo Giudice, Paola Argiento, Gavino Casu, Marco Corda, Michele Correale, Stefano Ghio, Alessandra Greco, Mariangela Lattanzio, Valentina Mercurio, Giuseppe Paciocco, Silvia Papa, Renato Prediletto, Emanuele Romeo, Maria Giovanna Russo, Alessandro Tayar, Patrizio Vitulo, Carmine Dario Vizza, Paolo Golino, Robert Naeije,

BACKGROUND:Upfront combination therapy with ambrisentan and tadalafil has been reported to improve the condition of patients with pulmonary arterial hypertension (PAH) more than with either drug alone. However, little is known about the long-term associated changes in hemodynamics and risk assessment scores. METHODS:This was a multicenter, retrospective analysis of clinical ... Read more >>

J. Heart Lung Transplant. (The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation)
[2020, :]

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Molecular T-cell‒mediated rejection in transbronchial and mucosal lung transplant biopsies is associated with future risk of graft loss.

Kieran Halloran, Michael D Parkes, Irina Timofte, Gregory Snell, Glen Westall, Jan Havlin, Robert Lischke, Ramsey Hachem, Daniel Kreisel, Deborah Levine, Bartosz Kubisa, Maria Piotrowska, Stephen Juvet, Shaf Keshavjee, Peter Jaksch, Walter Klepetko, Alim Hirji, Justin Weinkauf, Philip F Halloran,

BACKGROUND:We previously developed molecular assessment systems for lung transplant transbronchial biopsies (TBBs) with high surfactant and bronchial mucosal biopsies, identifying T-cell‒mediated rejection (TCMR) on the basis of the expression of rejection-associated transcripts, but the relationship of rejection to graft loss is unknown. This study aimed to develop molecular assessments for ... Read more >>

J. Heart Lung Transplant. (The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation)
[2020, :]

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Hemostasis during extracorporeal membrane oxygenation: More questions.

Lin Chen, Zhongheng Zhang, Kun Chen,

J. Heart Lung Transplant. (The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation)
[2020, :]

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Longitudinal lung function measurements in single lung transplant recipients with chronic lung allograft dysfunction.

Gabriela Leuschner, Michael Lauseker, Anne-Sophie Howanietz, Katrin Milger, Tobias Veit, Dieter Munker, Christian Schneider, Thomas Weig, Sebastian Michel, Jürgen Barton, Bruno Meiser, Julien Dinkel, Claus Neurohr, Jürgen Behr, Nikolaus Kneidinger,

BACKGROUND:Phenotyping chronic lung allograft dysfunction (CLAD) in single lung transplant (SLTX) recipients is challenging. The aim of this study was to assess the diagnostic and prognostic value of longitudinal lung function tests in SLTX recipients with CLAD. METHODS:A total of 295 SLTX recipients were analyzed and stratified according to native ... Read more >>

J. Heart Lung Transplant. (The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation)
[2020, :]

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Cytomegalovirus replication is associated with enrichment of distinct γδ T cell subsets following lung transplantation: A novel therapeutic approach?

Sanda Stankovic, Martin S. Davey, Evangeline M. Shaw, Anouk von Borstel, Yvonne Cristiano, Bronwyn J. Levvey, Jamie Rossjohn, Glen P. Westall, Gregory I. Snell, Andrew G. Brooks, Lucy C. Sullivan,

BACKGROUND Anti-viral treatments to control cytomegalovirus (CMV) after lung transplantation (LTx) are associated with toxicity and anti-viral resistance. Cellular immunotherapy with virus-specific cytotoxic T cells has yielded promising results but requires donor/recipient matching. γδ T cells are involved in anti-viral immunity and can recognize antigens independently of major histocompatibility complex ... Read more >>

J. Heart Lung Transplant. (The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation)
[2020, :]

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Outcomes in the 2018 UNOS donor heart allocation system: A perspective on disparate analyses.

Anubodh S Varshney, Sameer A Hirji, Michael M Givertz,

The United Network for Organ Sharing (UNOS) implemented a revised donor heart allocation system on October 18, 2018 with principle aims to reduce waitlist mortality, enhance geographic organ sharing, and improve organ distribution equity. Five recently published analyses compared outcomes of heart transplant (HT) recipients transplanted under the revised versus ... Read more >>

J. Heart Lung Transplant. (The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation)
[2020, :]

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Geographic and temporal patterns of growth in the utilization of donation after circulatory death donors for lung transplantation in the United States.

Sameer A Hirji, Alison L Halpern, Laura J Helmkamp, Sophia H Roberts, Anna K Houk, Asishana Osho, Alexis K Okoh, Robert A Meguid, Laura Seese, Michael J Weyant, Daniel E Rinewalt,

J. Heart Lung Transplant. (The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation)
[2020, :]

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Cytomegalovirus replication is associated with enrichment of distinct γδ T cell subsets following lung transplantation: A novel therapeutic approach?

Sanda Stankovic, Martin S Davey, Evangeline M Shaw, Anouk von Borstel, Yvonne Cristiano, Bronwyn J Levvey, Jamie Rossjohn, Glen P Westall, Gregory I Snell, Andrew G Brooks, Lucy C Sullivan,

BACKGROUND:Anti-viral treatments to control cytomegalovirus (CMV) after lung transplantation (LTx) are associated with toxicity and anti-viral resistance. Cellular immunotherapy with virus-specific cytotoxic T cells has yielded promising results but requires donor/recipient matching. γδ T cells are involved in anti-viral immunity and can recognize antigens independently of major histocompatibility complex molecules ... Read more >>

J. Heart Lung Transplant. (The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation)
[2020, :]

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Platelet activation after withdrawal of life support in donation after circulatory death donors.

Sarah E Scheuer, Claudio Soto, Joanne Joseph, Paul C Jansz, Peter S Macdonald,

J. Heart Lung Transplant. (The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation)
[2020, :]

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Combined heart-lung transplantation from a donation after circulatory death donor.

Simon Messer, Yasir Abu-Omar, Stephen R Large, Marius Berman, Aravinda Page, Pradeep Kaul, J E Arrowsmith, Richard Quigley, Caitlin Cheshire, Caroline Patterson, Debra Thomas, John Wallwork, Jasvir Parmar, Pedro Catarino,

Combined heart-lung transplantation is the optimal treatment option for many patients with end-stage heart failure and fixed severe pulmonary hypertension. It offers the only possibility of long-term survival and a return to a normal quality of life. Unfortunately, it is rarely performed because of donor organ allocation policies. We present ... Read more >>

J. Heart Lung Transplant. (The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation)
[2020, :]

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High-intensity interval training in patients with left ventricular assist devices: A pilot randomized controlled trial.

Ignacio Moreno-Suarez, Anna Scheer, Kaitlyn Lam, Lawrence Dembo, Angela L Spence, Christopher Hayward, David M Kaye, Angela Leet, Louise M Fuller, Angela Jacques, Louise H Naylor, Daniel J Green, Andrew Maiorana,

BACKGROUND:Left ventricular assist device (LVAD) implantation is an established treatment for patients with advanced heart failure. To date, studies evaluating the impact of aerobic training in patients with LVADs have focused on moderate-intensity exercise. METHODS:This pilot randomized controlled trial compared the effects of high-intensity interval training (HIIT) with those of ... Read more >>

J. Heart Lung Transplant. (The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation)
[2020, :]

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International experience using a durable, centrifugal-flow ventricular assist device for biventricular support.

Silvana Marasco, André R Simon, Steven Tsui, René Schramm, Sandra Eifert, Christian M Hagl, Mustafa Paç, Ümit Kervan, Arnt E Fiane, Florian M Wagner, Jens Garbade, Mustafa Özbaran, Christopher S Hayward, Daniel Zimpfer, Jan D Schmitto,

BACKGROUND:Heart transplantation is limited by the scarcity of suitable donors. Patients with advanced biventricular failure may require biventricular support to provide optimal cardiac output and end-organ perfusion. We highlight the outcomes of using the HeartWare HVAD System (HVAD) in a biventricular configuration. METHODS:This retrospective study included patients implanted with HVAD ... Read more >>

J. Heart Lung Transplant. (The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation)
[2020, :]

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Secular changes in organ donor profiles and impact on heart and lung transplantation.

Josef Stehlik, Mandeep R Mehra,

J. Heart Lung Transplant. (The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation)
[2020, 39(10):997-1002]

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Tumor necrosis factor-α inhibitor use for treatment of refractory cardiac sarcoidosis in a patient with left ventricular assist device: Adalimumab use in refractory sarcoidosis in a patient with left ventricular assist device.

Mrinalini Krishnan, Thomas R Cupps, Farooq H Sheikh,

J. Heart Lung Transplant. (The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation)
[2020, :]

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Surveillance for cardiac allograft vasculopathy: Practice variations among 50 pediatric heart transplant centers.

Deipanjan Nandi, Clifford Chin, Kurt R Schumacher, Matthew Fenton, Rakesh K Singh, Kimberly Y Lin, Jennifer Conway, Ryan S Cantor, Devin A Koehl, Jacqueline M Lamour, James K Kirklin, Elfriede Pahl,

BACKGROUND:Coronary allograft vasculopathy (CAV) is a leading cause of mortality after heart transplantation (HT) in children. Variation in CAV screening practices may impact detection rates and patient outcomes. METHODS:Among 50 Pediatric Heart Transplant Society (PHTS) sites from 2001 to 2016, coronary evaluations were classified as angiography or non-invasive testing, and ... Read more >>

J. Heart Lung Transplant. (The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation)
[2020, :]

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Long-term outcome of orthotopic heart transplantation in Asians: An analysis of the United Network of Organ Sharing database.

Shun Kohsaka, Yasuhiro Shudo, Hanjay Wang, Bharathi Lingala, Masataka Kawana, Y Joseph Woo,

J. Heart Lung Transplant. (The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation)
[2020, :]

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Clinical characteristics and outcomes of patients with adult congenital heart disease listed for heart and heart‒lung transplantation in the Eurotransplant region.

Peter Moritz Becher, Benedikt Schrage, Jessica Weimann, Jacqueline Smits, Christina Magnussen, Hermann Reichenspurner, Alina Goßling, Inez Rodrigus, Julia Dumfarth, Michel de Pauw, Katrien François, Olivier van Caenegem, Arnaut Ancion, Johan Van Cleemput, Davor Milicic, Ajay Moza, Peter Schenker, Luise Röhrich, Felix Schönrath, Josef Thul, Michael Steinmetz, Bastian Schmack, Arjang Ruhparwar, Gregor Warnecke, Sebastian V Rojas, Tim Sandhaus, Assad Haneya, Sandra Eifert, Henryk Welp, László Ablonczy, Florian Wagner, Dirk Westermann, Alexander M Bernhardt, Dorit Knappe, Stefan Blankenberg, Paulus Kirchhof, Elvin Zengin, Christoph Sinning,

BACKGROUND:The therapeutic success in patients with congenital heart disease (CHD) leads to a growing number of adults with CHD (adult CHD [ACHD]) who develop end-stage heart failure. We aimed to determine patient characteristics and outcomes of ACHD listed for heart transplantation. METHODS:Using data from all the patients with ACHD in ... Read more >>

J. Heart Lung Transplant. (The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation)
[2020, :]

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Identifying host microRNAs in bronchoalveolar lavage samples from lung transplant recipients infected with Aspergillus.

Wajiha Gohir, William Klement, Lianne G Singer, Scott M Palmer, Tony Mazzulli, Shaf Keshavjee, Shahid Husain,

BACKGROUND:MicroRNAs (miRNAs) are small non-coding RNAs of ∼22 nucleotides that play a crucial role in post-transcriptional regulation of gene expression. Dysregulation of miRNA expression has been shown during microbial infections. We sought to identify miRNAs that distinguish invasive aspergillosis (IA) from non-IA in lung transplant recipients (LTRs). METHODS:We used NanoString ... Read more >>

J. Heart Lung Transplant. (The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation)
[2020, :]

Cited: 0 times

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The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: 37th adult lung transplantation report - 2020; focus on deceased donor characteristics.

Daniel C Chambers, Andreas Zuckermann, Wida S Cherikh, Michael O Harhay, Don Hayes, Eileen Hsich, Kiran K Khush, Luciano Potena, Aparna Sadavarte, Tajinder P Singh, Josef Stehlik, ,

J. Heart Lung Transplant. (The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation)
[2020, 39(10):1016-1027]

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A CLUE for better assessment of donor lungs: Novel technique in clinical ex vivo lung perfusion.

Kamal S Ayyat, Toshihiro Okamoto, Hiromichi Niikawa, Ichiro Sakanoue, Siddharth Dugar, Samir Q Latifi, Daniel J Lebovitz, Ajit Moghekar, Kenneth R McCurry,

BACKGROUND:The direCt Lung Ultrasound Evaluation (CLUE) technique was proven to be an accurate method for monitoring extravascular lung water in donor lungs during ex vivo lung perfusion (EVLP) in an experimental model. The aim of this study was to examine the application of CLUE in the clinical setting. METHODS:Lungs were ... Read more >>

J. Heart Lung Transplant. (The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation)
[2020, :]

Cited: 0 times

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