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Elevated circulating cell-free DNA levels in autoimmune bullous diseases.

Yuki Kakitsuka, Soichiro Sawamura, Ikko Kajihara, Hisashi Kanemaru, Noritoshi Honda, Katsunari Makino, Jun Aoi, Takamitsu Makino, Satoshi Fukushima, Hironobu Ihn,

J. Dermatol. (The Journal of dermatology)
[2020, :]

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Use of proton pump inhibitors and risk of rosacea: A nationwide population-based study.

Ying-Xiu Dai, Ying-Hsuan Tai, Chih-Chiang Chen, Yun-Ting Chang, Tzeng-Ji Chen, Mu-Hong Chen,

Proton pump inhibitors (PPI) are commonly used drugs. However, little is known about the association between PPI use and rosacea. This study aimed to investigate the association between PPI use and rosacea risk. Patients with prior PPI therapy, including 1067 rosacea cases and 4268 matched controls, were identified from the ... Read more >>

J. Dermatol. (The Journal of dermatology)
[2020, :]

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Case of inflammatory arthritis induced by encorafenib and binimetinib in a patient with melanoma.

Yoshihiro Matsudate,

J. Dermatol. (The Journal of dermatology)
[2020, :]

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Clinical characteristics, genetics, comorbidities and treatment of palmoplantar pustulosis: A retrospective analysis of 66 cases in a single center in Taiwan.

Chang-Ming Huang, Tsen-Fang Tsai,

We retrospectively analyzed 66 patients with palmoplantar pustulosis (PPP) from January 1994 to September 2019 in our department. Interleukin-36 receptor antagonist gene (IL36RN) intron 3 c.115+6T>C mutation was present in two out of 27 patients (7.4%). Both cases developed generalized pustular psoriasis and/or acrodermatitis continua of Hallopeau later. Topical medications ... Read more >>

J. Dermatol. (The Journal of dermatology)
[2020, :]

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Wound, pressure ulcer and burn guidelines - 1: Guidelines for wounds in general, second edition.

Minoru Hasegawa, Yuji Inoue, Sakae Kaneko, Hiroyuki Kanoh, Yoichi Shintani, Jun Tsujita, Hideki Fujita, Sei-Ichiro Motegi, Andres Le Pavoux, Jun Asai, Yoshihide Asano, Masatoshi Abe, Masahiro Amano, Ryuta Ikegami, Takayuki Ishii, Taiki Isei, Zenzo Isogai, Takaaki Ito, Ryokichi Irisawa, Yohei Iwata, Masaki Otsuka, Yoichi Omoto, Hiroshi Kato, Takafumi Kadono, Tamihiro Kawakami, Masakazu Kawaguchi, Ryuichi Kukino, Takeshi Kono, Monji Koga, Masanari Kodera, Keisuke Sakai, Eiichi Sakurai, Yasuko Sarayama, Miki Tanioka, Hideaki Tanizaki, Naotaka Doi, Takeshi Nakanishi, Akira Hashimoto, Masahiro Hayashi, Kuninori Hirosaki, Manabu Fujimoto, Hiroshi Fujiwara, Takeo Maekawa, Koma Matsuo, Naoki Madokoro, Hiroshi Yatsushiro, Osamu Yamasaki, Yuichiro Yoshino, Takao Tachibana, Hironobu Ihn,

The Japanese Dermatological Association prepared the clinical guidelines for the "Wound, pressure ulcer and burn guidelines", second edition, focusing on treatments. Among them, "Guidelines for wounds in general" is intended to provide the knowledge necessary to heal wounds, without focusing on particular disorders. It informs the basic principles of wound ... Read more >>

J. Dermatol. (The Journal of dermatology)
[2020, :]

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Epidermal growth factor receptor deficiency: Expanding the phenotype beyond infancy.

Brian R Earl, Marta Szybowska, Ashish Marwaha, Vladimir Belostotsky, Irene Lara-Corrales, Elena Pope, Peter Kannu,

Transmembrane tyrosine kinase receptors represent a fundamental mechanism for transducing extracellular signals into the activation of signaling cascades responsible for intercellular communication, embryogenesis and tissue integrity. The epidermal growth factor receptor (EGFR) is a canonical member of this family, regarded for its dysregulated function in various malignancies. Here, we describe ... Read more >>

J. Dermatol. (The Journal of dermatology)
[2020, :]

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Frequent brain metastases during treatment with BRAF/MEK inhibitors: A retrospective single institutional study.

Yoshiyuki Nakamura, Yosuke Ishitsuka, Ryota Tanaka, Naoko Okiyama, Rei Watanabe, Akimasa Saito, Junichi Furuta, Yasuhiro Fujisawa,

Recent clinical trials revealed that both immune checkpoint inhibitors (ICI) and BRAF/MEK inhibitors significantly prolonged survival in melanoma patients when used for both advanced stage disease and postoperative adjuvant therapy. Although BRAF/MEK inhibitors are associated with a higher objective response rate than ICI, most patients relapse during treatment. However, progression ... Read more >>

J. Dermatol. (The Journal of dermatology)
[2020, :]

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Increased level of high mobility group box 1 in the serum and skin in patients with generalized pustular psoriasis.

Tomoya Watanabe, Yukie Yamaguchi, Yuko Watanabe, Naoko Takamura, Michiko Aihara,

High-mobility group box 1 (HMGB-1) is a highly abundant pro-inflammatory protein associated with the pathogenesis of inflammatory and autoimmune diseases. HMGB-1 expression level increases in patients with psoriasis vulgaris (PV). However, HMGB-1 expression in patients with generalized pustular psoriasis (GPP) is unknown. In this study, we investigated HMGB-1 expression in ... Read more >>

J. Dermatol. (The Journal of dermatology)
[2020, :]

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Durvalumab-induced de novo annular psoriasiform drug eruption successfully treated with a combination of narrowband ultraviolet B phototherapy and topical treatment.

Wei-Hsi Lin, Kang-Yun Lee, Woan-Ruoh Lee, Yi-Hsien Shih,

Immune checkpoint inhibitors, including anti-programmed death 1 and anti-programmed death ligand 1, have become prominent treatment options for various types of cancers. However, immune checkpoint inhibitors are associated with various cutaneous adverse events, one of which is psoriasiform drug eruption. Some cases of psoriasiform drug eruption can only be controlled ... Read more >>

J. Dermatol. (The Journal of dermatology)
[2020, :]

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Case of keratosis punctata of the palmar creases showing a possible association with hyperkeratosis in sweat pores.

Shiho Sunami, Gyohei Egawa, Kenji Kabashima,

J. Dermatol. (The Journal of dermatology)
[2020, :]

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iPhone charger-induced chemical burn from overnight contact with sweat: Two cases.

Yuki Nakagawa, Takafumi Uchida, Shin Morizane,

Smartphones have become essential devices in modern society. The coverage rate of smartphones in 2017 in Japan was 75% according to the Ministry of Internal Affairs and Communications. The iPhone is one of the most well-known smartphone brands. According to the manufacturer of iPhones (Apple), more than 200 million iPhones had ... Read more >>

J. Dermatol. (The Journal of dermatology)
[2020, :]

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Tinea manuum caused by Trichophyton erinacei.

Takasuke Ogawa, Yumi Ogawa, Masataro Hiruma, Rui Kano, Shigaku Ikeda,

J. Dermatol. (The Journal of dermatology)
[2020, :]

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Infant case of generalized pustular psoriasis preceded by interstitial lung disease.

Natsuko Noguchi, Takahiko Sato, Hiroyuki Adachi, Takuya Nagai, Yayoi Tomura, Aya Toyoshima, Tsutomu Takahashi, Motomu Manabe, Shin-Ichi Osada,

J. Dermatol. (The Journal of dermatology)
[2020, :]

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Impact of Riehl's melanosis on quality of life in Korean patients: A cross-sectional comparative study.

Yu Ri Woo, Yujin Jung, Miri Kim, Hyun Jeong Park,

The prevalence of Riehl's melanosis in Korea is increasing. However, little is known about the psychosocial burden of patients with Riehl's melanosis. This study was aimed to examine the level of psychosocial impact of Riehl's melanosis. A cross-sectional study recruited 52 patients with Riehl's melanosis who were asked to complete ... Read more >>

J. Dermatol. (The Journal of dermatology)
[2020, :]

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Unexpected side-effect of dupilumab: Reversal of hair graying.

Chiho Sumitomo, Hirotaka Akita, Kazumitsu Sugiura,

J. Dermatol. (The Journal of dermatology)
[2020, :]

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Acquired idiopathic partial anhidrosis successfully treated with adapalene gel.

Takeshi Fukumoto, Mariko Sugiyama, Atsushi Fukunaga, Chikako Nishigori,

J. Dermatol. (The Journal of dermatology)
[2020, :]

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Paradoxical adverse events in the oral cavity caused by anti-tumor necrosis factor-α therapy for pustulotic arthro-osteitis.

Sonoko Ito, Yukihiko Kato, Hiroko Wakimoto, Kaoru Nishiwaki, Kae Onishi, Tasuo Mori, Naoto Yokogawa,

J. Dermatol. (The Journal of dermatology)
[2020, :]

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Mild epidermolytic ichthyosis with palmoplantar keratoderma due to the KRT1 mutation p.lle479Thr.

Yuya Murase, Kana Tanahashi, Takuya Takeichi, Kazumitsu Sugiura, Akiteru Aiyama, Keigo Nishida, Teruyuki Mitsuma, Masashi Akiyama,

J. Dermatol. (The Journal of dermatology)
[2020, :]

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Long-lasting allergic patch test reactions to dental metal allergens in a patient with palmoplantar pustulosis and pustulotic arthro-osteitis.

Maiko Kato, Naoki Oiso, Shigeto Yanagihara, Akira Kawada,

J. Dermatol. (The Journal of dermatology)
[2020, :]

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Cold urticaria comorbid with heat urticaria: A case report.

Takahiro Ohashi, Yuji Kan, Hiroyuki Takahashi, Daisuke Yoneta, Kimi Kase, Yasuyuki Sumikawa, Hisashi Uhara,

J. Dermatol. (The Journal of dermatology)
[2020, :]

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Higher prevalence of thyroid dysfunction in patients with erythrodermic psoriasis.

Jianfeng Zheng, Yunlu Gao, Na Liu, Ying Li, Fujuan Chen, Ning Yu, Yangfeng Ding, Xuemei Yi,

The association of psoriasis with thyroid dysfunction has been investigated. However, it remains unclear; some papers indicate it, and others do not. In this study, we evaluate the prevalence of thyroid dysfunction in patients with psoriasis vulgaris (PsV), psoriatic arthritis (PsA), generalized pustular psoriasis (GPP) and erythrodermic psoriasis (EP), and ... Read more >>

J. Dermatol. (The Journal of dermatology)
[2020, :]

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Successful treatment of cutaneous infection due to Purpureocillium lilacinum using voriconazole.

Rika Suzuki, Yukiko Kiniwa, Takushi Shirai, Yuko Takazawa, Tatsuya Natori, Takashi Mochizuki, Ryuhei Okuyama,

J. Dermatol. (The Journal of dermatology)
[2020, :]

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Higher baseline serum lactate dehydrogenase level is associated with poor effectiveness of dupilumab in the long term in patients with atopic dermatitis.

Aika Kato, Masahiro Kamata, Makoto Ito, Hideaki Uchida, Mayumi Nagata, Saki Fukaya, Kotaro Hayashi, Atsuko Fukuyasu, Takamitsu Tanaka, Takeko Ishikawa, Takamitsu Ohnishi, Yayoi Tada,

Dupilumab shows high efficacy and tolerable safety for the treatment of atopic dermatitis (AD). However, the extent of its effectiveness varies in individual patients. To date, practical predictors of later effectiveness of dupilumab in AD patients have not been reported. To explore practical predictors of later effectiveness of dupilumab in ... Read more >>

J. Dermatol. (The Journal of dermatology)
[2020, :]

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Scalp microbiota in members of a Japanese high school judo team including Trichophyton tonsurans carriers.

Taketoshi Futatsuya, Tsuyoshi Ushigami, Fumie Nomura, Kazushi Anzawa, Takashi Mochizuki, Otomi Cho, Takashi Sugita,

Trichophyton tonsurans is a major causative fungus of human dermatophytosis, which has been isolated from contact sport players in Japan. The microbiome in the scalp of judoists with or without T. tonsurans infection was analyzed to investigate the correlation between T. tonsurans infection and microbiome profile. Among 30 members of the same ... Read more >>

J. Dermatol. (The Journal of dermatology)
[2020, :]

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Heterogeneity in the linear shiny white structures in melanomas seen with polarized light according to histopathological association: Cross-sectional observational study in 118 cutaneous melanomas.

José Bañuls, Laura Francés, Maria Niveiro, Gloria Juan, Luca Schneller-Pavelescu, Francisco Illán, José Sánchez-Payá, Eduardo Nagore, Ignacio Moreno, Aimilios Lallas, Pedro Zaballos,

Polarized dermoscopy enables visualization of linear shiny white structures in melanomas, thought to be due to the existence of fibrosis in the dermis. Our objective was to establish the existence of two types of linear shiny white structures and assess their association with different histological structures. We performed a cross-sectional ... Read more >>

J. Dermatol. (The Journal of dermatology)
[2020, :]

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