Full Text Journal Articles in
Journal J. Cell. Biochem.

Advertisement

Find full text journal articles






NDV-D90 inhibits 17β-estradiol-mediated resistance to apoptosis by differentially modulating classic and nonclassic estrogen receptors in breast cancer cells.

Peng Shan, Bo Tang, Shanshan Xie, Zengling Zhang, Jiehou Fan, Zheng Wei, Chun Song,

Newcastle disease virus (NDV) is endowed with the oncolytic ability to kill tumor cells, while rarely causing side effects in normal cells. Both estrogen receptor α (ERα) and the G protein estrogen receptor (GPER) modulate multiple biological activities in response to estrogen, including apoptosis in breast cancer (BC) cells. Here, ... Read more >>

J. Cell. Biochem. (Journal of cellular biochemistry)
[2020, :]

Cited: 0 times

View full text PDF listing >>



GTPases Arf5 and Arl2 function partially distinctly during oocyte meiosis.

Chun-Xiang Zhou, Yang Wang, Li-Ya Shi, Zi-Bin Wang, Yang Ma, Cong-Rong Li, Na-Na Zhang, Ye-Xiao Zhang, Fenli Zhang, Dong Zhang, Zheng-Rong Xia,

Mammalian female meiosis must be tightly regulated to produce high-quality mature oocytes for subsequent regular fertilization and healthy live birth of the next generation. GTPases control many important signal pathways involved in diverse cellular activities. ADP-ribosylation factor family members (Arfs) in mice possess GTPase activities, and some members have been ... Read more >>

J. Cell. Biochem. (Journal of cellular biochemistry)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Advertisement

REST-repressed lncRNA NPPA-AS1 regulates cervical cancer progression by modulating miR-302e/DKK1/Wnt/β-catenin signaling pathway.

Yanan Luan, Bin Xie, Wenbin Wei,

Long noncoding RNAs (lncRNAs), a group of transcripts, have been revealed to be critical participants in regulating multiple biological processes of malignant tumors. The knowledge of NPPA-AS1 (a new lncRNA) in cancer research is hardly known. Thus, it is of urgent need to study the underlying role of NPPA antisense ... Read more >>

J. Cell. Biochem. (Journal of cellular biochemistry)
[2020, :]

Cited: 0 times

View full text PDF listing >>



SP1-induced lncRNA FOXD3-AS1 contributes to tumorigenesis of cervical cancer by modulating the miR-296-5p/HMGA1 pathway.

Wen-Guang Ma, Si-Mao Shi, Lu Chen, Ge Lou, Xiao-Ling Feng,

Long noncoding RNAs (lncRNAs) have drawn growing attention due to their regulatory roles in various diseases, including tumors. Recently, lncRNA FOXD3 antisense RNA 1 (FOXD3-AS1) was shown to be overexpressed in colon adenocarcinoma and glioma, exerting oncogenic functions. However, its expression and effects in cervical cancer (CC) remained unknown. In ... Read more >>

J. Cell. Biochem. (Journal of cellular biochemistry)
[2020, :]

Cited: 0 times

View full text PDF listing >>



lncRNA-POIR promotes epithelial-mesenchymal transition and suppresses sorafenib sensitivity simultaneously in hepatocellular carcinoma by sponging miR-182-5p.

Bryan Wei Chen, Yue Zhou, Tao Wei, Liang Wen, Yi-Bo Zhang, Shi-Chao Shen, Jian Zhang, Tao Ma, Wen Chen, Lei Ni, Yi Wang, Xue-Li Bai, Ting-Bo Liang,

Sorafenib (SOR) resistance remains a major obstacle in the effective treatment of hepatocellular carcinoma (HCC). A number of long noncoding RNAs (lncRNAs) are responsible for this chemoresistance. This study aimed to reveal the essential function of a recently defined lncRNA, lncRNA-POIR, in the epithelial-mesenchymal transition (EMT) and SOR sensitivity of ... Read more >>

J. Cell. Biochem. (Journal of cellular biochemistry)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Comparative assessment of immunomodulatory, proliferative, and antioxidant activities of crocin and crocetin on mesenchymal stem cells.

Forouzan Yousefi, Fahimeh L Arab, Maryam Rastin, Nafiseh S Tabasi, Karim Nikkhah, Mahmoud Mahmoudi,

Saffron (Crocus sativus L) is a well-known spice with active pharmacologic components including crocin, crocetin, safranal, and picrocrocin. Similar to crocin/crocetin, mesenchymal stem cells (MSCs) have been shown to display immunomodulatory and antioxidant properties, which could be beneficial in treatment of various diseases. In the current study, we have evaluated ... Read more >>

J. Cell. Biochem. (Journal of cellular biochemistry)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Stomatin is highly expressed in exosomes of different origin and is a promising candidate as an exosomal marker.

Gleb O Skryabin, Andrei V Komelkov, Sergey A Galetsky, Dmitry V Bagrov, Evgeniy G Evtushenko, Igor I Nikishin, Kirill I Zhordaniia, Elizaveta E Savelyeva, Maria E Akselrod, Iulia G Paianidi, Elena M Tchevkina,

Proteins involved in the organizing of lipid rafts can be found in exosomes, as shown for caveolin-1, and they could contribute to exosomal cargo sorting, as shown for flotillins. Stomatin belongs to the same stomatin/prohibitin/flotillin/HflK/C family of lipid rafts proteins, but it has never been studied in exosomes except for ... Read more >>

J. Cell. Biochem. (Journal of cellular biochemistry)
[2020, :]

Cited: 0 times

View full text PDF listing >>



A short review: Doxorubicin and its effect on cardiac proteins.

Shishir Upadhyay, Kunj Bihari Gupta, Anil Kumar Mantha, Monisha Dhiman,

Doxorubicin (DOX) is a boon for cancer-suffering patients. However, the undesirable effect on health on vital organs, especially the heart, is a limiting factor, resulting in an increased number of patients with cardiac dysfunction. The present review focuses on the contractile machinery and associated factors, which get affected due to DOX toxicity ... Read more >>

J. Cell. Biochem. (Journal of cellular biochemistry)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Serotonin receptor type 2B activation augments TNF-α-induced matrix mineralization in murine valvular interstitial cells.

Felicia Fong, Joshua Xian, Linda L Demer, Yin Tintut,

Calcification, fibrosis, and chronic inflammation are the predominant features of calcific aortic valve disease, a life-threatening condition. Drugs that induce serotonin (5-hydroxytryptamine [5-HT]) are known to damage valves, and activated platelets, which carry peripheral serotonin, are known to promote calcific aortic valve stenosis. However, the role of 5-HT in valve ... Read more >>

J. Cell. Biochem. (Journal of cellular biochemistry)
[2020, :]

Cited: 0 times

View full text PDF listing >>



PARK7 enhances antioxidative-stress processes of BMSCs via the ERK1/2 pathway.

Fei Zhang, Wuxun Peng, Jian Zhang, Lei Wang, Wentao Dong, Yinggang Zheng, Zhenwen Wang, Zhihong Xie, Tao Wang, Chuan Wang, Yanglin Yan,

Oxidative stresss in the microenvironment surrounding lesions induces apoptosis of transplanted bone-marrow-derived mesenchymal stem cells (BMSCs). Hence, there is an urgent need for improving antioxidative-stress processes of transplanted BMSCs to further promote their survival. The present study reports the role and mechanism of Parkinson's disease protein 7 (PARK7) in enhancing antioxidative activity ... Read more >>

J. Cell. Biochem. (Journal of cellular biochemistry)
[2020, :]

Cited: 0 times

View full text PDF listing >>



miR-145 attenuates cardiac fibrosis through the AKT/GSK-3β/β-catenin signaling pathway by directly targeting SOX9 in fibroblasts.

Shengyu Cui, Zhebo Liu, Bo Tao, Suzhen Fan, Yong Pu, Xiangping Meng, Dongqing Li, Hao Xia, Lin Xu,

Myocardial infarction (MI) will inevitably result in cardiac fibrosis. In this study, we investigated the effect of microRNA-145 (miR-145) and transcription factor sex-determining region Y box 9 (SOX9) in the production of cardiac fibrosis induced by MI. MI rat models were established by left anterior descending coronary artery (LAD) occlusion. ... Read more >>

J. Cell. Biochem. (Journal of cellular biochemistry)
[2020, :]

Cited: 0 times

View full text PDF listing >>



microRNA-320a prevent Müller cells from hypoxia injury by targeting aquaporin-4.

Zhen Chen, Zhengrong Yang, Xiaoliang Li, He Wang, Yonggang Wang, Chao Ding, JingYing Yang, Ninghua Ni, Yan Mei, Shiwen Zhang,

Müller cells are closely related to diabetic retinopathy (DR). Aquaporin-4 (AQP4) can effectively promote the diffusion of water across cellular membranes. However, the dynamic balance of water plays key role in many diseases, such as cerebral edema. Meanwhile, the unusual expression and distribution of AQP4 in the retina are the ... Read more >>

J. Cell. Biochem. (Journal of cellular biochemistry)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Membrane dynamics of γ-secretase with the anterior pharynx-defective 1B subunit.

Budheswar Dehury, Kasper P Kepp,

The four-subunit protease complex γ-secretase cleaves many single-pass transmembrane (TM) substrates, including Notch and β-amyloid precursor protein to generate amyloid-β (Aβ), central to Alzheimer's disease. Two of the subunits anterior pharynx-defective 1 (APH-1) and presenilin (PS) exist in two homologous forms APH1-A and APH1-B, and PS1 and PS2. The consequences ... Read more >>

J. Cell. Biochem. (Journal of cellular biochemistry)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Circadian transcription factor Dbp promotes rat calvarial osteoprogenitors osteogenic differentiation through Kiss1/GnRH/E2 signaling pathway loop.

Yanhui Zhao, Yanan Wu, Jie Wang, Chongshan Liao, Xiaohui Mi, Fengshan Chen,

To determine the mechanism by which D-site-binding protein (Dbp) regulates rat calvarial osteoprogenitors (OPCs) osteogenic differentiation. α-Smooth muscle actin (α-SMA) + rat calvarial OPCs were extracted and purified using immunomagnetic beads. Cells were transduced with Dbp-lentivirus and divided into Dbp knockdown, Dbp overexpression and vehicle groups. After osteogenic induction for 21 days, ... Read more >>

J. Cell. Biochem. (Journal of cellular biochemistry)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Identification of mitochondrial function-associated lncRNAs in septic mice myocardium.

Yingzhou Shi, Xiaohe Zheng, Mingzhi Zheng, Linlin Wang, Yingying Chen, Yueliang Shen,

The present study aimed to analyze long noncoding RNA (lncRNA) and messenger RNA (mRNA) expression profiles in septic mice heart and to identify potential lncRNAs and mRNAs that be responsible for cardiac mitochondrial dysfunction during sepsis. Mice were treated with 10 mg/kg of lipopolysaccharides to induce sepsis. LncRNAs and mRNAs expression ... Read more >>

J. Cell. Biochem. (Journal of cellular biochemistry)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Cancer metastasis-associated protein 1 localizes to the nucleolus and regulates pre-rRNA synthesis in cancer cells.

Jian Liu, Chunxiao Li, Hongsheng Xue, Lina Li, Qun Liu, Haijuan Wang, Tao Wen, Haili Qian,

Metastasis-associated protein 1 (MTA1) is a critical component of the nucleosome remodeling and histone deacetylase (NuRD) complex. MTA1 has several biological functions, and it is closely associated with the malignant properties of human cancers; however, the mechanisms and subcellular localization of MTA1 in cells remain unclear. Some initial studies indicated ... Read more >>

J. Cell. Biochem. (Journal of cellular biochemistry)
[2020, :]

Cited: 0 times

View full text PDF listing >>



The SUMO-specific protease SENP1 deSUMOylates p53 and regulates its activity.

Krishna M Chauhan, Yingxiao Chen, Yiyi Chen, Andrew T Liu, Xiao-Xin Sun, Mu-Shui Dai,

The stability and activity of the p53 tumor suppressor protein are tightly regulated by various posttranslational modifications, including SUMOylation. p53 can be modified by both SUMO1 and SUMO2, although how SUMOylation regulates p53 activity is still obscure. Whether p53 activity is directly regulated by deSUMOylation is also unclear. Here, we ... Read more >>

J. Cell. Biochem. (Journal of cellular biochemistry)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Long noncoding RNA LEF1-AS1 acts as a microRNA-10a-5p regulator to enhance MSI1 expression and promote chemoresistance in hepatocellular carcinoma cells through activating AKT signaling pathway.

Jun Gao, Chao Dai, Xin Yu, Xiang-Bao Yin, Fan Zhou,

Long noncoding RNAs (lncRNAs) contribute to the development of hepatocellular carcinoma (HCC), which could regulate various HCC biological characteristics. Here, the study seeks to investigate the role of lncRNA LEF1-AS1 in HCC cell chemoresistance by regulating microRNA (miR)-10a-5p and Musashi1 (MSI1). The microarray-based analysis was employed to identify the HCC-related ... Read more >>

J. Cell. Biochem. (Journal of cellular biochemistry)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Alkaline phosphatase dual-binding sites for collagen dictate cell migration and microvessel assembly in vitro.

Susana G Guerreiro, Ronald E Unger, Nuno M F S A Cerqueira, Anne Sartoris, Maria J Martins, Mário A Barbosa, Raquel Soares, Pedro L Granja, Charles J Kirkpatrick,

Interactions between cell types, growth factors, and extracellular matrix components involved in angiogenesis are crucial for new vessel formation leading to tissue regeneration. This study investigated whether cocultures of fibroblasts and endothelial cells (ECs; from macro- or microvasculature) play a role in the formation of microvessel-like structures by ECs, as ... Read more >>

J. Cell. Biochem. (Journal of cellular biochemistry)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Ubiquilin proteins regulate EGFR levels and activity in lung adenocarcinoma cells.

Zimple Kurlawala, Kumar Saurabh, Rain Dunaway, Parag P Shah, Leah J Siskind, Levi J Beverly,

Ubiquilin (UBQLN) proteins are involved in diverse cellular processes like endoplasmic reticulum-associated degradation, autophagy, apoptosis, and epithelial-to-mesenchymal transition. UBQLNs interact with a variety of substrates, including cell surface receptors, transcription factor regulators, proteasomal machinery proteins, and transmembrane proteins. In addition, previous work from our lab shows that UBQLN1 interacts with ... Read more >>

J. Cell. Biochem. (Journal of cellular biochemistry)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Identification of biomarkers correlated with diagnosis and prognosis of endometrial cancer using bioinformatics analysis.

Huishan Zhao, Aihua Jiang, Mingwei Yu, Hongchu Bao,

Endometrial cancer (EC) is one of the most common malignancies in the female genital system, characterized by high mortality and recurrence rates. This study attempted to screen key genes and potential prognostic biomarkers for EC using bioinformatics analysis. Twenty-seven normal endometrial tissues and 135 EC samples were collected from four ... Read more >>

J. Cell. Biochem. (Journal of cellular biochemistry)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Structural and posttranslational analysis of human calcium-binding protein, spermatid-associated 1.

Marcelo Marcet-Palacios, Eduardo Reyes-Serratos, Aron Gonshor, Robert Buck, Paige Lacy, A D Befus,

Recently, we detected a novel biomarker in human saliva called calcium-binding protein, spermatid-associated 1 (CABS1). CABS1 protein had previously been described only in testis, and little was known of its characteristics other than it was considered a structurally disordered protein. Levels of human CABS1 (hCABS1) in saliva correlate with stress, ... Read more >>

J. Cell. Biochem. (Journal of cellular biochemistry)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Stem cell therapies for COVID-19: Strategy and application.

Radbod Darabi, Yong Li,

In this perspective, the potential application of stem cells for the treatment of COVID-19 related pneumonia and their potential mechanism of action have been overviewed. ... Read more >>

J. Cell. Biochem. (Journal of cellular biochemistry)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Platelet microparticles-derived miR-25-3p promotes the hepatocyte proliferation and cell autophagy via reducing B-cell translocation gene 2.

Yuyuan Xu, Wenfei Li, Guangyu Liang, Jie Peng, Xuwen Xu,

Platelets are critical regulators of liver regeneration, but the mechanisms are still not fully understood. Platelets have been shown to contain a wide variety of microRNAs (miRNAs) and play an important role in many diseases. However, the mechanism that how the platelet microparticles (PMPs)-derived miRNA regulate the hepatocyte proliferation is ... Read more >>

J. Cell. Biochem. (Journal of cellular biochemistry)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Fluorescent multiplexing of 3D spheroids: Analysis of biomarkers using automated immunohistochemistry staining platform and multispectral imaging.

Srabani Bhaumik, Jean Boyer, Chaitali Banerjee, Samantha Clark, Noemi Sebastiao, Elizabeth Vela, Penny Towne,

In preclinical cancer studies, three-dimensional (3D) cell spheroids and aggregates are preferred over monolayer cell cultures due to their architectural and functional similarity to solid tumors. We performed a proof-of-concept study to generate physiologically relevant and predictive preclinical models using non-small cell lung adenocarcinoma, and colon and colorectal adenocarcinoma cell ... Read more >>

J. Cell. Biochem. (Journal of cellular biochemistry)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Advertisement

Disclaimer
0.95 s