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Journal J Trauma Acute Care Surg

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Propranolol Attenuates Cognitive, Learning and Memory Deficits in a Murine Model of Traumatic Brain Injury.

Muhammad Zeeshan, Mohammad Hamidi, Terence O'Keeffe, Kamil Hanna, Randall S Friese, Narong Kulvatunyou, El Rasheid Zakaria, Lynn Gries, Andrew Tang, Bellal Joseph,

β-blockers have been shown to improve survival after traumatic brain injury (TBI), however, the impact of continuous dosage of β-blockers on cognitive function has not been elucidated. We hypothesized that a daily dose of propranolol can improve memory, learning and cognitive function following TBI.Twenty male-C57BL-mice were subjected to a cortical-controlled ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2019, :]

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Use of ShotSpotterTM detection technology decreases prehospital time for patients sustaining gunshot wounds.

Anna Goldenberg, Deviney Rattigan, Michael Dalton, John P Gaughan, J Scott Thomson, Kyle Remick, Christopher Butts, Joshua P Hazelton,

BACKGROUND:Shorter prehospital time in patients sustaining penetrating trauma has been shown to be associated with improved survival. Literature has also demonstrated that police transport (vs. EMS) shortens transport times to a trauma center. The purpose of this study was to determine if ShotSpotter, which triangulates the location of gunshots and ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2019, :]

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Letter to the editor (Infection after penetrating brain injury).

Stacy A Voils, Bethany R Shoulders, Veena Venugopalan,

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2019, :]

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The Utility of MRI in Pediatric Trauma Patients Suspected of Having Cervical Spine Injuries.

S Christopher Derderian, Krista Greenan, David M Mirsky, Nicholas V Stence, Sarah Graber, Todd C Hankinson, Noah Hubbell, Allyson Alexander, Brent R O'Neill, C Corbett Wilkinson, Michael H Handler,

BACKGROUND:Pediatric cervical spine injuries (CSI) are rare but potentially devastating sequelae of blunt trauma. Existing protocols to evaluate children at risk for CSI frequently incorporate computerized topography (CT) and magnetic resonance imaging (MRI); however, the clinical value of performing both remains unclear. METHODS:Single center retrospective review of pediatric trauma patients ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2019, :]

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The Sequential Clinical Assessment of Respiratory Function (SCARF) Score: A Dynamic Pulmonary Physiologic Score that Predicts Adverse Outcomes in Critically Ill Rib Fracture Patients.

Kimberly S Hardin, Kiara N Leasia, James Haenel, Ernest E Moore, Clay Cothren Burlew, Fredric M Pieracci,

BACKGROUND:Rib fracture scoring systems are limited by a lack of serial pulmonary physiologic variables. We created the Sequential Clinical Assessment of Respiratory Function (SCARF) score and hypothesized that admission, maximum, and rising scores predict adverse outcomes among critically ill rib fracture patients. METHODS:Prospective cohort study of rib fracture patients admitted ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2019, :]

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Ketamine Infusion for Pain Control in Elderly Patients with Multiple Rib Fractures: Results of a Randomized Controlled Trial.

Nathan W Kugler, Thomas W Carver, Janelle Juul, William J Peppard, Kelly Boyle, Karin Madsen Drescher, Aniko Szabo, Lisa Rein, Lewis B Somberg, Jasmeet S Paul,

INTRODUCTION:Rib fractures are associated with increased mortality, particularly in the elderly. While opiate-based pain regimens remain the cornerstone of rib fracture management, issues related to opioids have driven research into alternative analgesics. Adjunctive ketamine use in lieu of opioids continues to increase but little evidence exists to support its efficacy ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2019, :]

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Random Forest Modeling Can Predict Infectious Complications Following Trauma Laparotomy.

Rondi B Gelbard, Hannah Hensman, Seth Schobel, Vivek Khatri, Brett Tracy, Christopher J Dente, Timothy Buchman, Allan Kirk, Eric Elster,

BACKGROUND:Identifying clinical and biomarker profiles of trauma patients may facilitate the creation of models that predict postoperative complications. We sought to determine the utility of modeling for predicting severe sepsis (SS) and organ space infections (OSI) following laparotomy for abdominal trauma. METHODS:Clinical and molecular biomarker data were collected prospectively from ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2019, :]

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Interim monitoring of non-randomized prospective studies that invoke propensity scoring for decision-making.

Stacia M DeSantis, Michael D Swartz, Thomas J Greene, Erin E Fox, John B Holcomb, Charles E Wade, ,

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2019, :]

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Selective Nonoperative Management of Renal Gunshot Wounds.

Morgan Schellenberg, Elizabeth Benjamin, Alice Piccinini, Kenji Inaba, Demetrios Demetriades,

BACKGROUND:Selective nonoperative management (SNOM) of blunt kidney injuries has been the standard of care for decades. However, the role of SNOM after renal gunshot wounds (GSWs) remains unclear. The purpose of this study was to assess the safety and outcomes of SNOM of renal GSWs at a national level. METHODS:The ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2019, :]

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The IDF Experience with Freeze Dried Plasma For The Resuscitation of Traumatized Pediatric Patients.

Roy Nadler, Yael Mozer-Glassberg, Barbara Gaines, Elon Glassberg, Jacob Chen,

INTRODUCTION:With the growing recognition of the disadvantages of crystalloid and colloid based resuscitation and the advantages of using blood products as the preferred resuscitation fluid, the Israel Defense Forces Medical Corps (IDF-MC) adopted plasma as the primary volume resuscitation regimen in 2013. While data are accumulating for prehospital plasma transfusion, ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2019, :]

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The effect of cirrhosis on trauma outcomes: A systematic review and meta-analysis.

Elina Serrano, Pingyang Liu, Adaobi I Nwabuo, Simone Langness, Catherine Juillard,

BACKGROUND:The negative effect of cirrhosis on mortality following traumatic injury has been quantified in multiple observational studies. However, to our knowledge, the information contained in these studies has never been synthesized. The aims of this study were: 1) to determine the magnitude of the effect of liver cirrhosis on mortality, ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2019, :]

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It's About Time: Transfusion Effects on Post-Injury Platelet Aggregation Over Time.

Lucy Z Kornblith, Anna Decker, Amanda S Conroy, Carolyn M Hendrickson, Alexander T Fields, Anamaria J Robles, Rachael A Callcut, Mitchell J Cohen,

BACKGROUND:Impaired post-injury platelet aggregation is common, but the effect of transfusion on this remains unclear. Data suggests that following injury platelet transfusion may not correct impaired platelet aggregation and impaired platelet aggregation may not predict the need for platelet transfusion. We sought to further investigate platelet aggregation responses to transfusions, ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2019, :]

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Letter to the Editor.

John R Hall,

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2019, :]

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Resuscitative endovascular balloon occlusion of the inferior vena cava is made hemodynamically possible by concomitant endovascular balloon occlusion of the aorta - a porcine study.

Maria B Wikström, Johannes Krantz, Tal M Hörer, Kristofer F Nilsson,

BACKGROUND:Resuscitative endovascular balloon occlusion of the vena cava inferior (REBOVC) may provide a minimal invasive alternative for hepatic vascular and inferior vena cava isolation in severe retrohepatic bleeding. However, circulatory stability may be compromised by the obstruction of venous return. The aim was to explore which combinations of arterial and ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2019, :]

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Prospective Evaluation and Comparison of The Predictive Ability of Different Frailty Scores to Predict Outcomes in Geriatric Trauma Patients.

Mohammad Hamidi, Zaid Haddadin, Muhammad Zeeshan, Abdul Tawab Saljuqi, Kamil Hanna, Andrew Tang, Ashley Northcutt, Narong Kulvatunyou, Lynn Gries, Bellal Joseph,

BACKGROUND:Different frailty scores have been proposed to measure frailty. No study has compared their predictive ability to predict outcomes in trauma patients. The aim of our study was to compare the predictive ability of different frailty scores to predict complications, mortality, discharge disposition and 30-day readmission in trauma patients. METHODS:We ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2019, :]

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Location, Location, Location: Utilizing NBATS-2 in Trauma System Planning.

Jennings H Dooley, Esra Ozdenerol, John P Sharpe, Louis J Magnotti, Martin A Croce, Peter E Fischer,

INTRODUCTION:In 2015, the American College of Surgeons Committee on Trauma introduced the Needs-Based Assessment of Trauma Systems (NBATS) tool to quantify the optimal number of trauma centers for a region. While useful, more focus was required on injury population, distribution, and transportation systems. Therefore, NBATS-2 was developed utilizing advanced geographical ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2019, :]

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Comparison of the Causes of Death and Wounding Patterns in Urban Firearm-Related Violence and Civilian Public Mass Shooting Events.

Sam Maghami, Cheralyn Hendrix, Mary Matecki, Karthika Mahendran, Richard Amdur, Roger Mitchell, Francisco Diaz, Jordan Estroff, E Reed Smith, Geoff Shapiro, Babak Sarani,

BACKGROUND:There are no reports comparing wounding pattern in urban and public mass shooting events (CPMS). Because CPMS receive greater media coverage, there is a connation that the nature of wounding is more grave than daily urban gun violence. We hypothesize that the mechanism of death following urban GSWs is the ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2019, :]

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Dose Optimization of Valproic Acid in a Lethal Model of Traumatic Brain Injury, Hemorrhage and Polytrauma in Swine.

Ben E Biesterveld, Aaron M Williams, Manjunath P Pai, Isabel S Dennahy, Nathan J Graham, Kiril Chtraklin, Ali Z Siddiqui, Rachel L O'Connell, Umar F Bhatti, Baoling Liu, Rachel M Russo, Yongqing Li, Hasan B Alam,

BACKGROUND:Trauma is a leading cause of death, and traumatic brain injury (TBI) is one of the hallmark injuries of current military conflicts. VPA administration in high doses (300-400 mg/kg) improves survival in lethal trauma models, but effectiveness of lower doses on survival is unknown. This information is essential for properly ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2019, :]

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A Novel Protocol to Maintain Continuous Access to Thawed Plasma at a Rural Trauma Center.

Cara Hannigan, Gabriel Ologun, Andrew Trecartin, Lauren Colom, Ry Bloomdahl, Amanda Seyer, Lisa LaRock, Barbara Tubby, Burt Cagir, Jason Granet, Robert Behm,

BACKGROUND:Early administration of plasma improves mortality in massively transfused patients, but the thawing process causes delay. Small rural centers have been reluctant to maintain thawed plasma due to waste concerns. Our 254-bed rural level II trauma center initiated a protocol allowing continuous access to thawed plasma and we hypothesized its ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2019, :]

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Cold-Stored Whole Blood: A Better Method of Trauma Resuscitation?

Joshua P Hazelton, Jeremy W Cannon, Catherine Zatorski, Janika San Roman, Sarah A Moore, Andrew J Young, Madhu Subramanian, Jessica Guzman, Franz Fogt, Anna Moran, John Gaughan, Mark J Seamon, John Porter,

INTRODUCTION:Cold-stored whole blood (CWB) provides a balance of red blood cells, plasma, and platelets in less anticoagulant volume than standard blood component therapy (BCT). We hypothesize that patients receiving CWB along with BCT have improved survival compared to patients receiving only BCT. METHODS:We performed a dual-center case-match study of trauma ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2019, :]

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Disproportionally Low Funding for Trauma Research by the National Institutes of Health: A Call for a National Institute of Trauma.

Nina E Glass, Julia Riccardi, Nicole I Farber, Stephanie L Bonne, David H Livingston,

BACKGROUND:Trauma is a major cause of death and disability in all ages. Previous reviews have suggested that NIH funding for trauma is not commensurate with its burden of disease, but a detailed analysis has been lacking. We postulated that NIH spending on trauma research was lower than previously thought and ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2019, :]

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THE HEALTH LITERACY OF HOSPITALIZED TRAUMA PATIENTS: WE SHOULD BE SCREENING FOR DEFICIENCIES.

Jordan A Weinberg, Mahmoud Z Shehada, Kristina M Chapple, Sharjeel Israr, Michael D Jones, Jordan V Jacobs, James N Bogert,

BACKGROUND:Although the impact of health literacy (HL) on trauma patient outcomes remains unclear, recent studies have demonstrated that trauma patients with deficient HL have poor understanding of their injuries, are less likely to comply with follow-up, and are relatively less satisfied with physician communication. In this study, we sought to ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2019, :]

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End Tidal Carbon Dioxide Underestimates Plasma Carbon Dioxide During Emergent Trauma Laparotomy Leading to Hypoventilation and Misguided Resuscitation: A Western Trauma Association Multicenter Study.

Eric M Campion, Caitlin K Robinson, Nicholson Brant, Lisa Ferrigno, Robert McIntyre, Ben Biesterveld, Hasan Alam, Rachael Callcut, Somya Mishra, Blake Platt, Margaret M Moore, Jeffry Nahmias, Areg Grigorian, Sarah Dance, Linda Britton, Thomas Schroeppel, Jennifer Rodriquez, David Shatz, James Becker, M Chance Spalding, Timothy W Wolff, Alicia R Privette, Evert Eriksson, Saad Liaqat Sahi, Anish Patel, Scott M Moore, Anquonette L Stiles, Ernest E Moore, Mitchell J Cohen, Angela Sauaia, Clay Cothren Burlew, Shane Urban, Pascal Udekwu, Megan Nguyen, Ashley Dibbert, Amanda Conroy, Erin Ross, Brenda Nunez Garcia, Spencer Albertson, Julie Dunn, Omar Alnachaoukati, Zachery Stillman, Cassie Decker, Holly Heise, Josh S Burton, ,

BACKGROUND:End tidal carbon dioxide(ETCO2) is routinely used during elective surgery to monitor ventilation. The role of ETCO2 monitoring in emergent trauma operations is poorly understood. We hypothesized that ETCO2 values underestimate plasma carbon dioxide(pCO2) values during resuscitation for hemorrhagic shock. METHODS:Multicenter trial was performed analyzing the correlation between ETCO2 and ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2019, :]

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Meckel's diverticulum and the eponymous legend.

Rao R Ivatury,

Johann Friedrich Meckel (1781-1833) was a 19th century anatomist born into an eminent dynasty. He was a professor of anatomy, pathology, and zoology at the University of Halle, in Central Germany. The diverticulum, a congenital remnant of the vitellointestinal duct was named after him. Other eponyms include Meckel's cartilage, Meckel ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2019, 87(2):451-455]

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Featured Articles for CME Credit August 2019.

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2019, 87(2):e5-e8]

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