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Prevalence of Unrecognized Autism Spectrum Disorders in Epilepsy: A Clinic-Based Study.

Mahmood D Al-Mendalawi,

J Pediatr Neurosci (Journal of pediatric neurosciences)
[2020, 15(1):65]

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Reports of a Conus Cauda Tumor with Holocord Syrinx in an Adolescent Girl.

Smriti Sinha, Prathibha Shankar Ashwini, Pelala Nayan Baba, Rathika Damodar Shenoy,

Introduction:Spinal cord ependymoma seldom presents with holocord syringomyelia in pediatric age-group. Association of ependymoma with a lipoma is also rare. The child presented critically ill with polymicrobial pneumonia, and the neurologic findings were missed until recovery. We report a case highlighting these findings. Case Report:A 16-year-old adolescent presented critically ill ... Read more >>

J Pediatr Neurosci (Journal of pediatric neurosciences)
[2020, 15(1):51-53]

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Electroclinical Findings of SYNJ1 Epileptic Encephalopathy.

Debopam Samanta, Kapil Arya,

Introduction:Early-onset epileptic encephalopathies are among the most severe early-onset epilepsies, leading to progressive neurodegeneration. An increasing number of novel genetic causes continue to be uncovered as the primary etiology. Results:We report a girl infant of Semitic (Saudi Arabian) descent who presented with multifocal seizures and later developed intractable infantile spasms ... Read more >>

J Pediatr Neurosci (Journal of pediatric neurosciences)
[2020, 15(1):29-33]

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Relation between Febrile Seizure Recurrence and Hyponatremia in Children: A Single-center Trial.

Mohammad Reza Navaeifar, Ali Abbaskhanian, Akram Farmanbarborji,

Background:Febrile seizure (FS) is one of the most common types of seizure in pediatrics. Objective:The aim of this study was to compare serum sodium in children with simple or recurrent FS and seizure without fever. Materials and Methods:This was a cross-sectional prospective study conducted between September 2015 and April 2017 ... Read more >>

J Pediatr Neurosci (Journal of pediatric neurosciences)
[2020, 15(1):5-8]

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Coexistence of Type 1 Diabetes Mellitus and Periventricular Heterotopia in a Child: A Case Report.

Faruk Incecik, Fatih Gürbüz,

J Pediatr Neurosci (Journal of pediatric neurosciences)
[2020, 15(1):67-68]

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An Unusual Presentation of Menkes Disease Masquerading as a Leukodystrophy with Macrocephaly.

Anshula Tayal, Aman Elwadhi, Suvasini Sharma, Bijoy Patra,

Background:Menkes disease is an X-linked neurodegenerative disease caused by mutation in ATP7A gene, which codes for copper-transporting ATPase. It usually presents in early infancy with neuro-regression, hypotonia, seizures, and kinky hair. Magnetic resonance imaging (MRI) of the brain shows cerebral atrophy, subdural effusions, and tortuous cerebral blood vessels. Case Characteristics:We ... Read more >>

J Pediatr Neurosci (Journal of pediatric neurosciences)
[2020, 15(1):57-59]

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Multiple Tubercular Brain Abscesses with Obstructive Hydrocephalus in an Immunocompetent Child: A Case Report.

Ipsita K Sahoo, Amit K Satapathy, Joseph John,

Tubercular brain abscesses are rare manifestations in children, and very few cases have been reported till date. It is characterized by an encapsulated collection of pus, containing viable tubercular bacilli. Antitubercular treatment (ATT) is the mainstay of treatment along with surgical drainage or aspiration or excision of the abscess. We ... Read more >>

J Pediatr Neurosci (Journal of pediatric neurosciences)
[2020, 15(1):38-41]

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Intravenous Levetiracetam for Treatment of Seizures in Term and Preterm Neonates.

Pakize Karaoğlu, Semra Hız, Burçin İşcan, Ayşe I Polat, Müge Ayanoğlu, Nuray Duman, Uluç Yiş',

Context:Seizures are the most frequent neurological disturbance in the neonatal period, and there are no evidence-based guidelines for the treatment of neonatal seizures. Here we report a study on the use of levetiracetam as second-line therapy in the treatment of seizures in term and preterm neonates. Aim:The aim of this ... Read more >>

J Pediatr Neurosci (Journal of pediatric neurosciences)
[2020, 15(1):15-20]

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Miller Fisher Variant of Guillain-Barré Syndrome in a Child.

Sushant S Mane, Umesh Nagesh, Vaijinath T Sathe, Jyothi Janadhanan,

Miller Fisher syndrome (MFS), a rare form of Guillain-Barré Syndrome, presents with the classical triad of ophthalmoplegia, areflexia, and ataxia. We describe the case of a 7-year-old boy who presented with diplopia, speech difficulty, dysphagia, gait disturbance, and difficulty in eyeball movements since 5 days. On examination, the child was ... Read more >>

J Pediatr Neurosci (Journal of pediatric neurosciences)
[2020, 15(1):60-62]

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A Case of Split Notochord Syndrome with Left Congenital Diaphragmatic Hernia: A Rare Association.

Pradyumna Pan,

Split notochord syndrome is a rare neural tube malformation involving the brain, spinal cord, and vertebral column. In nearly half of the cases, the malformation also involves the gastrointestinal tract in the form of a dorsal neurenteric fistula and imperforate anus. In the literature, less than 50 cases have been ... Read more >>

J Pediatr Neurosci (Journal of pediatric neurosciences)
[2020, 15(1):42-44]

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Prevalence of Vitamin B12 Deficiency in West Syndrome: A Retrospective Chart Review.

Manjeet Singh, Mohit Bansal, Jaya S Kaushik,

Aims and Objectives:The aim of this study was to describe the vitamin B12 status among children treated for West syndrome and to review the clinical response to vitamin B12 supplementation among those found deficient. Materials and Methods:Hospital records of children with West syndrome with a minimum follow-up of 6 months ... Read more >>

J Pediatr Neurosci (Journal of pediatric neurosciences)
[2020, 15(1):21-24]

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Hereditary Chin Trembling.

Sedat Işikay,

J Pediatr Neurosci (Journal of pediatric neurosciences)
[2020, 15(1):66]

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A Case of Deep Cerebral Venous Thrombosis Presenting like Acute Necrotizing Encephalopathy.

Sachin Dangi, Namita Gwasikoti,

Acute necrotizing encephalopathy (ANEC) is a rapidly progressive neurologic disorder that occurs in children after common viral infections such as influenza A and herpes simplex virus. It is observed more commonly in Asian countries. Magnetic resonance imaging findings in ANEC include symmetrical brain lesions, preferentially affecting the thalamus bilaterally. However, ... Read more >>

J Pediatr Neurosci (Journal of pediatric neurosciences)
[2020, 15(1):54-56]

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Acute Hydrocephalus in a Case of Mumps Meningoencephalitis: A Rare Occurrence.

Anish Mehta, Rohan Mahale, Kiran Khanapure, Anirudh T Jagannatha, Purushottam Acharya, Rangasetty Srinivasa,

Mumps is an acute viral illness, which presents with glandular and/or nervous system involvement. The most common central nervous system manifestations of mumps include aseptic meningitis and meningoencephalitis. Mumps meningoencephalitis, which is characterized by fever, vomiting, nuchal rigidity, and altered sensorium, usually develops at least 3-10 days after mumps parotitis. ... Read more >>

J Pediatr Neurosci (Journal of pediatric neurosciences)
[2020, 15(1):34-37]

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Auditory and Visual P300 Responses in Early Cognitive Assessment of Children and Adolescents with Epilepsy.

Sangeeta Gupta, Arun Prasad, Ramji Singh, Gaurav Gupta,

Background:The event-related potential P300 has been suggested to be valuable in the assessment of cognitive dysfunctions. Not a great deal of neurophysiological assessment has been performed at early stages in patients with epilepsy involving visual and auditory P300 measures. Aims and Objectives:This study aimed to assess the cognitive status in ... Read more >>

J Pediatr Neurosci (Journal of pediatric neurosciences)
[2020, 15(1):9-14]

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Black Holes in the Brain and Spine: A Dark Disease.

Bhanudeep Singanamalla, Sumeet Dhawan, Arushi Gahlot Saini, Paramjeet Singh, Naveen Sankhyan,

A 7-year-old girl presented with difficulty in walking and bilateral vision impairment since past 15 days. On examination, she had disc pallor, flaccid paraparesis with positive Babinski sign, and reduced sensations below clavicle. She was diagnosed as anti-aquaporin-4 (AQP-4)-positive neuromyelitis optica. This article emphasizes the importance of recognizing its classical ... Read more >>

J Pediatr Neurosci (Journal of pediatric neurosciences)
[2020, 15(1):63-64]

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Myelopathy in Two Brothers with Respiratory Chain Disorder-Severe Complex 1 Deficiency with Atlantoaxial Dislocation and Long Spinal Arachnoid Cyst: A New Unreported Association.

Sadanandavalli Retnaswami Chandra, Hansashree Padmanabha, Manisha Gupta, Nupur Pruthi, Gayathri Narayanappa, Rita Christopher,

Billion of years ago bacteria is believed to have entered a eukaryotic cell and converted to mitochondria. The respiratory chain present in it supplies ATP to all cells and therefore the diseases can have any phenotype. Diagnosis may be difficult to confirm by the conventional methods including genetics. Two brothers ... Read more >>

J Pediatr Neurosci (Journal of pediatric neurosciences)
[2020, 15(1):45-50]

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A Rare Case of Sphenoid Encephalocoele Presenting with Fifth Cranial Nerve Involvement.

Rohit Wadikhaye, Vamsi Krishna Yerramneni, Thirumal Yerragunta, Neeraj Sharma,

A 14-year-old girl presented with chronic headache, recurrent episodes of vomiting, fever, and two episodes of generalized tonic clonic seizure in the past 2 months. Neuroimaging revealed herniation of the brain along with the dura through a defect in the left greater wing of the sphenoid. Left pterional craniotomy was ... Read more >>

J Pediatr Neurosci (Journal of pediatric neurosciences)
[2020, 15(1):25-28]

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Postoperative pneumoventricle following posterior fossa tumor surgery in sitting position: Plugging the aqueduct.

Dattatraya Muzumdar,

J Pediatr Neurosci (Journal of pediatric neurosciences)
[2020, 15(1):1-4]

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Unilateral Open-lip Schizencephaly with Tonsillar Herniation in a Preterm Infant.

Juan Carlos Gonzalez, Kanya Singhapakdi, Anthony M Martino, Bassam H Rimawi, Ramachandra Bhat,

Schizencephaly is a rare type of neuronal migration disorder characterized by the presence of a cerebral hemispheric cleft that extends from lateral ventricles to the cortical surface of the brain. We report a rare case of prenatally diagnosed unilateral schizencephaly in a late preterm infant who manifested with rapidly progressive ... Read more >>

J Pediatr Neurosci (Journal of pediatric neurosciences)
[2019, 14(4):225-227]

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Early Post-cooling Brain Magnetic Resonance for the Prediction of Neurodevelopmental Outcome in Newborns with Hypoxic-Ischemic Encephalopathy.

Mario Mastrangelo, Giulia Di Marzo, Flavia Chiarotti, Chiara Andreoli, Maria Chiara Colajacomo, Anna Ruggieri, Paola Papoff,

Aim and Objectives:This study aimed to evaluate the predictive role of early post-cooling brain magnetic resonance for developmental outcome in newborns with hypoxic-ischemic encephalopathy. Materials and Methods:A retrospective cohort study was performed on 29 consecutive patients through magnetic resonance evaluation (visual analysis of the images and scoring of the detected ... Read more >>

J Pediatr Neurosci (Journal of pediatric neurosciences)
[2019, 14(4):191-202]

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Hypocalcemic Recurrent Generalized Seizures with Bilateral Basal Ganglia and Frontal Calcification as the Initial Manifestation of Albright's Hereditary Osteodystrophy in a Child: A Pictorial and Video-graphic Representations.

Akhilesh Kumar Nunavath, Sandhya Manorenj, Srikant Jawalker, Bushra Naaz,

Albright hereditary osteodystrophy (AHO) is a hereditary metabolic disorder that presents with seizure secondary to hypocalcaemia. A careful phenotypic assessment of patients presenting with seizure clues to the diagnosis of AHO. The characteristic features are short stature,obesity and brachydactyly.Pseudohypoparathyroidism (PHP) is observed in patients with AHO and is characterized by ... Read more >>

J Pediatr Neurosci (Journal of pediatric neurosciences)
[2019, 14(4):232-235]

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Perioperative Management of Pediatric Giant Supratentorial Tumors: Challenges and Management Strategies.

Sangeetha R Palaniswamy, Manish Beniwal, Sudhir Venkataramaiah, Dwarakanath Srinivas,

Background:Intracranial tumors are the most common pediatric solid tumors. Only one-third of these tumors arise from the supratentorial compartment. The abnormal intracranial tumors are unusual but can bleed to an extent causing hemorrhagic shock necessitating blood transfusion in the perioperative period. The perioperative management of these subset of patients poses ... Read more >>

J Pediatr Neurosci (Journal of pediatric neurosciences)
[2019, 14(4):211-217]

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Chiari 1 malformation: Revisited.

Dattatraya Muzumdar,

J Pediatr Neurosci (Journal of pediatric neurosciences)
[2019, 14(4):179]

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Unilateral Cerebellar Hypoplasia: A Rare Cause of Childhood Seizures.

Minhaj Shaikh, Pushpinder Khera, Samhita Panda,

Cerebellar malformations are a rare group of disorders with clinical heterogeneity. The usual posterior fossa malformations comprise of the cystic lesions like Dandy-walker complex, enlarged cisterna magna or arachnoid cysts. The vermis is a commonly associated structure in both cystic and non-cystic posterior fossa malformations. The congenital malformations affecting the ... Read more >>

J Pediatr Neurosci (Journal of pediatric neurosciences)
[2019, 14(4):236-237]

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