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Journal J Orthop Surg Res

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Polymethyl methacrylate cure time in simulated in vivo total knee arthroplasty versus in vitro conditions.

Daniel A Funk, Quang-Viet Nguyen, Michael Swank,

The present means of confirming the cure of intra-operative polymethyl methacrylate (PMMA) cement are to wait for the remainder cement to harden. To our knowledge, there is no available technique to determine the precise moment of cure for in-vivo cement beneath the tibial tray. This study uses a novel means ... Read more >>

J Orthop Surg Res (Journal of orthopaedic surgery and research)
[2021, 16(1):629]

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Newer generation straight humeral nails allow faster bone healing and better functional outcome at mid-term.

Fabrizio Mocini, Giuseppe Rovere, Domenico De Mauro, Edoardo Giovannetti De Sanctis, Amarildo Smakaj, Giulio Maccauro, Francesco Liuzza,

Although proximal and diaphyseal humerus fractures are frequent, the optimal management remains controversial. Antegrade nailing prevents further damage to the soft tissues and to the vascularization, but it has been associated with postoperative shoulder pain and dysfunction. During the latest years a straight nail design was developed to minimize these ... Read more >>

J Orthop Surg Res (Journal of orthopaedic surgery and research)
[2021, 16(1):631]

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Plasma levels of D-dimer and fibrin degradation product are unreliable for diagnosing periprosthetic joint infection in patients undergoing re-revision arthroplasty.

Hong Xu, Jinwei Xie, Duan Wang, Qiang Huang, Zeyu Huang, Zongke Zhou,

The preoperative diagnosis of periprosthetic joint infection (PJI) in patients undergoing re-revision arthroplasty is crucial, so we evaluated whether plasma levels of D-dimer and fibrin degradation product (FDP) could aid such diagnosis. We retrospectively analyzed data on patients who underwent re-revision hip or knee arthroplasty at our institute during 2008-2020. ... Read more >>

J Orthop Surg Res (Journal of orthopaedic surgery and research)
[2021, 16(1):628]

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Three-dimensional morphological study of the proximal femur in Crowe type IV developmental dysplasia of the hip.

Yuhui Yang, Weihong Liao, Weiqun Yi, Hai Jiang, Guangtao Fu, Yuanchen Ma, Qiujian Zheng,

When performing femoral reconstruction in patients with Crowe type IV developmental dysplasia of the hip (DDH), anatomical deformity presents many technical challenges to orthopedic surgeons. The false acetabulum is suggested to influence load transmission and femoral development. The aim of this study was to describe the morphological features of dysplastic ... Read more >>

J Orthop Surg Res (Journal of orthopaedic surgery and research)
[2021, 16(1):621]

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Retraction Note to: Treatment comparison of femoral shaft with femoral neck fracture: a meta-analysis.

Yao Lu, Yakang Wang, Zhe Song, Qian Wang, Liang Sun, Cheng Ren, Hanzhong Xue, Zhong Li, Kun Zhang, Dingjun Hao, Yang Zhao, Teng Ma,

J Orthop Surg Res (Journal of orthopaedic surgery and research)
[2021, 16(1):610]

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Clinical value of MRI in evaluating and diagnosing of humeral lateral condyle fracture in children.

Yang Qi, Lin Guo, Man Sun, Zhi Wang,

Humeral lateral condyle fractures (HLCFs) are common paediatric fractures. Radiographs are hard to accurately evaluate and diagnose the damage of articular epiphyseal cartilage in HLCFs. 60 children who should be suspected to be HLCFs in clinical practice from Dec 2015 to Nov 2017 were continuously included as the first part ... Read more >>

J Orthop Surg Res (Journal of orthopaedic surgery and research)
[2021, 16(1):617]

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Gene correlation network analysis to identify regulatory factors in sciatic nerve injury.

Liuxun Li, Xiaokang Du, Haiqian Ling, Yuhang Li, Xuemin Wu, Anmin Jin, Meiling Yang,

Sciatic nerve injury (SNI), which frequently occurs under the traumatic hip and hip fracture dislocation, induces serious complications such as motor and sensory loss, muscle atrophy, or even disabling. The present work aimed to determine the regulating factors and gene network related to the SNI pathology. Sciatic nerve injury dataset ... Read more >>

J Orthop Surg Res (Journal of orthopaedic surgery and research)
[2021, 16(1):622]

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Greater presence of receptors for relaxin in the ligamentum teres of female infants who undergo open reduction for developmental dysplasia of the hip.

Semih Ayanoğlu, Haluk Çabuk, Fatmagül Kuşku Çabuk, Kubilay Beng, Timur Yildirim, Süheyla Uyar Bozkurt,

While many factors involved in the etiology of developmental dysplasia of the hip (DDH), one of which is the hormone relaxin. Relaxin concentrations in patients with DDH may lead to pathodynamic changes during hip development by altering the physiological nature of the ligament, as well as by long-term exposure to ... Read more >>

J Orthop Surg Res (Journal of orthopaedic surgery and research)
[2021, 16(1):627]

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Overexpression of FGF2 delays the progression of osteonecrosis of the femoral head activating the PI3K/Akt signaling pathway.

Pei Lu, Yi-Min Shen, Ting Hua, Ting Pan, Gang Chen, Teng Dai, Ke-Qin Shi,

The purpose of the current study was to explore the role and underlying mechanism of FGF-2 in dexamethasone (DEX)-induced apoptosis in MC3T3-E1 cells. GSE21727 was downloaded from the Gene Expression Omnibus (GEO) database to identify the differentially expressed genes (DEGs) by the limma/R package. MC3T3-E1 cells were exposed to DEX ... Read more >>

J Orthop Surg Res (Journal of orthopaedic surgery and research)
[2021, 16(1):613]

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Instability of the posterior pelvic ring: introduction of innovative implants.

Niklas Grüneweller, Dirk Wähnert, Thomas Vordemvenne,

Increasing numbers of posterior pelvic ring fractures, especially in elderly patients, demonstrate the need for soft tissue protecting surgical techniques. Standard of care is iliosacral screw osteosynthesis. This type of osteosynthesis has its limitations especially in patients with reduced bone properties. Therefore, the development of new and straightforward surgical techniques ... Read more >>

J Orthop Surg Res (Journal of orthopaedic surgery and research)
[2021, 16(1):625]

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LIPUS inhibits inflammation and catabolism through the NF-κB pathway in human degenerative nucleus pulposus cells.

Weiwei Yi, Qing Chen, Chuan Liu, Kaiting Li, Bailong Tao, Guihua Tian, Lu Zhou, Xiaohong Li, Jieliang Shen, Bo Liu, Zhenming Hu, Dawu Wang, Dingqun Bai,

Low-intensity pulsed ultrasound (LIPUS) is a safe and noninvasive rehabilitative physical therapy with anti-inflammatory effects. The current study investigated the effect of LIPUS on the inflammation of nucleus pulposus (NP) cells and its underlying mechanism. Human NP cells were acquired from lumbar disc herniation tissue samples and cultured for experiments. ... Read more >>

J Orthop Surg Res (Journal of orthopaedic surgery and research)
[2021, 16(1):619]

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MiR-4303 relieves chondrocyte inflammation by targeting ASPN in osteoarthritis.

Chunyu Wang, Li Wang, Xingfa Guan, Changfeng Yue,

Osteoarthritis (OA) is a severe articular cartilage disease whose pathogenesis involves the inflammation of chondrocytes. MicroRNAs (miRNAs) are considered to be effective inflammation regulators. However, the regulatory mechanism of miRNAs in osteoarthritis needs to be further elucidated. In this paper, we aim to investigate the underlying mechanisms by which miR-4303 ... Read more >>

J Orthop Surg Res (Journal of orthopaedic surgery and research)
[2021, 16(1):618]

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The global prevalence of osteoporosis in the world: a comprehensive systematic review and meta-analysis.

Nader Salari, Hooman Ghasemi, Loghman Mohammadi, Mohammad Hasan Behzadi, Elham Rabieenia, Shamarina Shohaimi, Masoud Mohammadi,

Osteoporosis affects all sections of society, including families with people affected by osteoporosis, government agencies and medical institutes in various fields. For example, it involves the patient and his/her family members, and government agencies in terms of the cost of treatment and medical care. Providing a comprehensive picture of the ... Read more >>

J Orthop Surg Res (Journal of orthopaedic surgery and research)
[2021, 16(1):609]

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Combined therapy of platelet-rich plasma and basic fibroblast growth factor using gelatin-hydrogel sheet for rotator cuff healing in rat models.

Takeshi Kataoka, Yutaka Mifune, Atsuyuki Inui, Hanako Nishimoto, Takashi Kurosawa, Kohei Yamaura, Shintaro Mukohara, Takehiko Matsushita, Takahiro Niikura, Yasuhiko Tabata, Ryosuke Kuroda,

Excellent outcomes of arthroscopic rotator cuff repair for small and medium tears have been recently reported. However, re-tears after surgery have been a common complication after surgical repair of large and massive rotator cuff tears and often occur in early postoperative phase. It was previously reported that basic fibroblast growth ... Read more >>

J Orthop Surg Res (Journal of orthopaedic surgery and research)
[2021, 16(1):605]

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Changes in patellar morphology following surgical correction of recurrent patellar dislocation in children.

Weifeng Li, Qian Wang, Hui Li, Shunyi Wang,

The aim of this study was to evaluate patellar morphological changes following surgical correction of recurrent patellar dislocation in children. A total of 35 immature children aged 5 to 10 years who suffered from bilateral recurrent patellar dislocation associated with abnormal patella morphology were enrolled in this study. The knees with ... Read more >>

J Orthop Surg Res (Journal of orthopaedic surgery and research)
[2021, 16(1):607]

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Cementless total hip arthroplasty for three different degrees of hip involved secondary to ankylosing spondylitis: an analysis of 195 hips.

Ping Mou, Hua Li, An-Jing Chen, Zheng Ji, Xin-Yi Dai, Zong-Ke Zhou,

Hip involved secondary to ankylosis spondylitis (AS) had a huge influence on hip function. Cementless total hip arthroplasty (THA) can improve hip function. However, no previous study compared the outcomes of THA for AS patients with three different degrees of hip involvement. The 195 hips were retrospectively analyzed and divided ... Read more >>

J Orthop Surg Res (Journal of orthopaedic surgery and research)
[2021, 16(1):608]

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Comparative study between admission, orthopaedic surgery, and economic trends during Covid-19 and non-Covid-19 pandemic in an Italian tertiary hospital: a retrospective review.

Gianluca Testa, Marco Sapienza, Fabrizia Rabuazzo, Annalisa Culmone, Fabiana Valenti, Andrea Vescio, Vito Pavone,

<h4>Background</h4>The COVID-19 pandemic represents one of the most massive health emergencies in the last century and has caused millions of deaths worldwide and a massive economic and social burden. The aim of this study was to evaluate how the COVID-19 pandemic-during the Italian lockdown period between 8 March and 4 ... Read more >>

J Orthop Surg Res (Journal of orthopaedic surgery and research)
[2021, 16(1):601]

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Identifying hub genes and immune infiltration of osteoarthritis using comprehensive bioinformatics analysis.

Zheng-Yuan Wu, Gang Du, Yi-Cai Lin,

Osteoarthritis (OA) is the most common chronic degenerative joint disorder globally that is characterized by synovitis, cartilage degeneration, joint space stenosis, and sub-cartilage bone hyperplasia. However, the pathophysiologic mechanisms of OA have not been thoroughly investigated. In this study, we conducted various bioinformatics analyses to identify hub biomarkers and immune ... Read more >>

J Orthop Surg Res (Journal of orthopaedic surgery and research)
[2021, 16(1):630]

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Comparative effectiveness of two methods for inducing osteoarthritis in a novel animal model, the Diannan small-ear pig.

Di Jia, Ruixian Zhang, Yinghong He, Guofeng Cai, Jiali Zheng, Yuye Yang, Yanlin Li,

<h4>Background</h4>Varieties of animals were used to study osteoarthritis pathogenesis. The Diannan small-ear pig, which is native to Yunnan, China, is thought to have an articular anatomy similar to that of humans and is more likely to be a source of pathological tissues than other animals. The aim of this study ... Read more >>

J Orthop Surg Res (Journal of orthopaedic surgery and research)
[2021, 16(1):594]

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The combined effect of vitamin K and calcium on bone mineral density in humans: a meta-analysis of randomized controlled trials.

Liyou Hu, Jindou Ji, Dong Li, Jing Meng, Bo Yu,

<h4>Background</h4>With the increasing incidence of osteoporosis, vitamin K and calcium have been linked to bone mineral density (BMD) and undercarboxylated osteocalcin (UcOC) in many studies, but the results of studies of the combined effect of vitamin K and calcium on BMD and UcOC in humans have been inconsistent. We conducted ... Read more >>

J Orthop Surg Res (Journal of orthopaedic surgery and research)
[2021, 16(1):592]

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The risk for complications and reoperations with the use of mega prostheses in bone reconstructions.

Christina Berger, Sofia Larsson, Peter Bergh, Helena Brisby, David Wennergren,

<h4>Background</h4>Despite a relatively high risk for complications and reoperations, mega prostheses are considered a useful method for reconstruction of bone defects after tumour resections. The total number of reoperations has not previously been described, and little is known about the complication rate of mega prostheses used for other indications than ... Read more >>

J Orthop Surg Res (Journal of orthopaedic surgery and research)
[2021, 16(1):598]

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Evaluation of the feasibility of acetabular cup pre-determination in revision total hip arthroplasty via X-ray of the bone stock of the anterosuperior acetabulum.

Jingwei Zhang, Keyu Kong, Yingjun Chi, Xiaoliang Liu, Yiming Zeng, Huiwu Li,

<h4>Purpose</h4>This study was aimed to explore (1) location on AP pelvic X-ray that displayed bone stock in anterosuperior acetabulum; (2) whether X-ray could provide enough evidence to evaluate whether bone stock could provide support for acetabular cup; (3) criteria to determine whether anterosuperior bone stock could provide sufficient support for ... Read more >>

J Orthop Surg Res (Journal of orthopaedic surgery and research)
[2021, 16(1):597]

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The biomechanical effect of the relevant segments after facet-disectomy in different diameters under posterior lumbar percutaneous endoscopes: a three-dimensional finite element analysis.

Yin Shi, Yi-Zhou Xie, Qun Zhou, Yang Yu, Xiao-Hong Fan,

<h4>Objective</h4>To evaluate the biomechanical influence after percutaneous endoscopic lumbar facetectomy in different diameters on segmental range of motion (ROM) and intradiscal pressure (IDP) of the relevant segments by establishing three dimensional finite element (FE) model.<h4>Methods</h4>An intact L3-5 model was successfully constructed from the CT of a healthy volunteer as Model ... Read more >>

J Orthop Surg Res (Journal of orthopaedic surgery and research)
[2021, 16(1):593]

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In vivo analysis of hip joint loading on Nordic walking novices.

Yannick Palmowski, Srdan Popovic, Simone G Schuster, Sebastian Hardt, Philipp Damm,

<h4>Objective</h4>To evaluate the influence of Nordic walking (NW) on hip joint loads in order to determine whether it can be safely performed during postoperative physiotherapy in patients after orthopeadic surgery of the hip.<h4>Methods</h4>Internal hip joint loads were directly measured in vivo in 6 patients using instrumented hip prostheses during NW ... Read more >>

J Orthop Surg Res (Journal of orthopaedic surgery and research)
[2021, 16(1):596]

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Poor outcomes of revision total knee arthroplasty in patients with septic loosening compared to patients with aseptic loosening.

Ji-Hoon Baek, Su Chan Lee, Hosun Jin, Jin-Woo Kim, Hye Sun Ahn, Chang Hyun Nam,

The purpose of this study was to compare the functional outcomes, activity levels, mortalities, implant survival rates, and complications in revision total knee arthroplasty (TKA) of patients with septic loosening with those in patients with aseptic loosening over a minimum 10-year follow-up period. A cohort of 78 patients (36 septic ... Read more >>

J Orthop Surg Res (Journal of orthopaedic surgery and research)
[2021, 16(1):624]

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