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LncRNA AFAP1-AS1 regulates proliferation and apoptosis of endometriosis through activating STAT3/TGF-β/Smad signaling via miR-424-5p.

Qing Huan, Shu-Chao Cheng, Zhan-Hui Du, Hui-Fen Ma, Cheng Li,

<h4>Aim</h4>Endometriosis is a common gynecological disorder characterized by chronic pelvic pain and infertility, which negatively affects women's health worldwide. AFAP1-AS1 has been implicated in endometriosis lesions recently, but its mechanism of endometriosis progression remains unclear.<h4>Methods</h4>Endometrial stromal cells (ESCs) were used to identify the role of AFAP1-AS1 in endometriosis. The migratory ... Read more >>

J Obstet Gynaecol Res (The journal of obstetrics and gynaecology research)
[2021, :]

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Tubal stump pregnancy after salpingectomy-Does the time interval from surgical intervention to conception matter?

Yaakov Melcer, Hilli Zur Naaman, Reut Hausman, Zvi Vaknin, Orna Levinsohn-Tavor, Ron Maymon, Noam Smorgick,

<h4>Aim</h4>Ectopic pregnancy implantation on the tubal stump after salpingectomy is a rare location for extrauterine pregnancy, whose pathogenesis is still unknown. The purpose of this study was to examine whether the time interval elapsed from salpingectomy may predispose the embryo to implantation on the tubal stump in the next pregnancy ... Read more >>

J Obstet Gynaecol Res (The journal of obstetrics and gynaecology research)
[2021, :]

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Preliminary evaluation of the short-term outcomes of polytetrafluoroethylene mesh for pelvic organ prolapse.

Kensaku Nakai, Akihiro Hamuro, Kohei Kitada, Mie Tahara, Takuya Misugi, Akemi Nakano, Masayasu Koyama, Daisuke Tachibana,

<h4>Aim</h4>Tension-free vaginal mesh (TVM) surgery using synthetic polypropylene (PP) soft mesh had spread rapidly. However, the frequency of mesh-related postoperative complications had increased, and PP was banned in April 2019. In Japan, however, transvaginal surgery using polytetrafluoroethylene (PTFE) mesh had been approved. In this study, we evaluated the clinical outcome ... Read more >>

J Obstet Gynaecol Res (The journal of obstetrics and gynaecology research)
[2021, :]

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Cardiovascular disease among pregnant women after anticancer therapy.

Chizuko Aoki-Kamiya, Wataru Shioyama, Yoshihisa Nakagawa, Jun Yoshimatsu,

Recent advances in cancer therapies have enabled many women diagnosed with malignancies during childhood and adolescence to survive longer and therefore to reach an age where they wish to conceive. When providing cancer treatment such as anticancer drugs and radiotherapy, attention is often paid to preserving future fertility, but little ... Read more >>

J Obstet Gynaecol Res (The journal of obstetrics and gynaecology research)
[2021, :]

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Changes of cerebral oxygenation indices measured by near infrared time-resolved spectroscopy during spinal anesthesia for cesarean section: Simultaneous measurement with cerebral blood flow.

Yusuke Itosu, Yasunori Kubo, Mamoru Morikawa, Hidemichi Watari, Yuji Morimoto,

<h4>Aim</h4>To measure the changes in cerebral oxygenation indices by near infrared time-resolved spectroscopy and the cerebral blood flow simultaneously after spinal anesthesia for cesarean section.<h4>Methods</h4>This prospective observational study was conducted for 25 pregnant women scheduled for elective cesarean section under spinal anesthesia. During a period of 15 min after spinal anesthesia, ... Read more >>

J Obstet Gynaecol Res (The journal of obstetrics and gynaecology research)
[2021, :]

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Assessing the concordance and accuracy between hospital discharge data, electronic health records, and register books for diagnosis of inpatient admissions of miscarriage: A retrospective linked data study.

Indra San Lazaro Campillo, Sarah Meaney, Maria Harrington, Karen McNamara, Anna Maria Verling, Paul Corcoran, Keelin O'Donoghue,

<h4>Background</h4>Despite the high prevalence of miscarriage, there are few studies which assess the concordance of a diagnosis of miscarriage in routinely collected health databases.<h4>Objectives</h4>To determine agreement and accuracy for the diagnosis of miscarriage between electronic health records (EHR), the Hospital Inpatient-Enquiry (HIPE) system, and hospital register books in Ireland.<h4>Methods</h4>This is ... Read more >>

J Obstet Gynaecol Res (The journal of obstetrics and gynaecology research)
[2021, :]

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Initiatives and achievements of the Japanese Society of Obstetrics and Gynecology, Obstetrics and Gynecology MIRAI Committee 2020.

Hiroaki Komatsu, Hidemichi Watari, Yohei Onodera, Tokumasa Suemitsu, Satoshi Nakagawa, Tae Kusabiraki, Yusuke Matoba, Kei Ihira, Nozomu Yanaihara, Kouji Banno, Aikou Okamoto, Makio Shozu, Tadashi Kimura, ,

<h4>Backgrounds</h4>In 2013, the total number of obstetrician-gynecologists decreased. The Japanese Society of Obstetrics and Gynecology established the Obstetrics and Gynecology MIRAI Committee in 2015. Within the MIRAI Committee, Japanese Trainees in Obstetrics and Gynecology (JTOG) was established; it was comprised of 20 promising young obstetrician-gynecologists recommended from regions across Japan. ... Read more >>

J Obstet Gynaecol Res (The journal of obstetrics and gynaecology research)
[2021, :]

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Nationwide survey (Japan) on spontaneous hemoperitoneum in pregnancy.

Miki Hagimoto, Hiroaki Tanaka, Yutaka Osuga, Kiyonori Miura, Shigeru Saito, Shoji Sato, Junichi Sugawara, Tomoaki Ikeda,

<h4>Aim</h4>The purpose of this study was to evaluate the current state and clinical characteristics of spontaneous hemoperitoneum in pregnancy (SHiP) in Japan by performing a comprehensive survey.<h4>Methods</h4>We reviewed data on pregnant women who developed SHiP during 2013-2017 (for 5 years), and were admitted to any of the perinatal centers in Japan. ... Read more >>

J Obstet Gynaecol Res (The journal of obstetrics and gynaecology research)
[2021, :]

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A survey of Japanese interns to prepare for mandatory clinical training in obstetrics and gynecology.

Yohei Onodera, Yusuke Matoba, Tokumasa Suemitsu, Manaka Shinagawa, Yosuke Sugita, Michinori Mayama, Kouji Banno, Nozomu Yanaihara, Hiroaki Komatsu, Makio Shozu, Hidemichi Watari,

<h4>Aim</h4>Obstetrics and gynecology (Ob/Gyn) training became compulsory for Japanese physician interns from April 2020 to improve medical competence in treating women's diseases. This study aims to understand the Ob/Gyn training needs of postgraduate year 1-2 physicians (interns) and thereby improve training efficiency.<h4>Methods</h4>This study was administered to interns at Ob/Gyn training ... Read more >>

J Obstet Gynaecol Res (The journal of obstetrics and gynaecology research)
[2021, :]

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Effect of adjuvant therapy on the prognosis in stage I/II uterine carcinosarcoma: A meta-analysis.

Fei Zhao, Ping Tan, Chang Wang, Xuechao Ji, Aiping Chen,

<h4>Introduction</h4>To assess the efficacy of adjuvant chemotherapy, radiotherapy, or both following the primary surgery on the progression-free survival and 5-year overall survival in patients with stage I/II uterine carcinosarcoma.<h4>Methods</h4>A preliminary investigation was conducted using PubMed and Embase databases to identify relevant studies published up to March, 2020. Pooled hazard ratios ... Read more >>

J Obstet Gynaecol Res (The journal of obstetrics and gynaecology research)
[2021, :]

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Relationship between magnetic resonance imaging-based classification of adenomyosis and disease severity.

Hiroshi Kobayashi, Sho Matsubara, Shogo Imanaka,

<h4>Aims</h4>The purpose of this study is to first investigate the correlation between image features and histological findings and the clinical severity of adenomyosis; second, search for imaging features to assess the type and locoregional extension of the disease; and finally, discuss the notation of image-based classification.<h4>Methods</h4>This paper combines a review ... Read more >>

J Obstet Gynaecol Res (The journal of obstetrics and gynaecology research)
[2021, :]

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Effects of an activity tracker with feedback on physical activity in women after midline laparotomy: A randomized controlled trial.

Jae Hong No, Kidong Kim, Yong Beom Kim, Dong Hoon Suh, Eun Joo Yang, Hee Hwang, Sooyoung Yoo,

<h4>Purpose</h4>To investigate whether the use of an activity tracker with feedback increases physical activity and is safe in patients who underwent a midline laparotomy for gynecologic disorders.<h4>Methods</h4>Patients who were planned to undergo a midline laparotomy for gynecologic diseases wore an activity tracker at baseline and from postoperative days 1-6. Patients ... Read more >>

J Obstet Gynaecol Res (The journal of obstetrics and gynaecology research)
[2021, :]

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Prevalence of umbilical artery Doppler waveform abnormality during the early second trimester and the subsequent variation of waveforms in monochorionic diamniotic twin pregnancies: A prospective cohort study.

Kentaro Nakanishi, Haruka Muto, Ryo Yamamoto, Haruna Kawaguchi, Shusaku Hayashi, Keisuke Ishii,

<h4>Aim</h4>To investigate the prevalence of qualitative abnormal umbilical artery Doppler waveforms (Abnormal UA) during the early second trimester and the subsequent variation of waveforms in monochorionic diamniotic (MCDA) twin pregnancies.<h4>Methods</h4>This prospective cohort study included 153 MCDA twin pregnancies. Pulsed Doppler examinations for UA were performed at four points, including the ... Read more >>

J Obstet Gynaecol Res (The journal of obstetrics and gynaecology research)
[2021, :]

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Decreased serum human leukocyte antigen-G levels are associated with gestational diabetes mellitus.

Ozer Oztekin, Umit Cabus, Yasar Enli,

<h4>Aim</h4>This study was designed to determine serum human leukocyte antigen-G (HLA-G) levels and establish whether serum HLA-G level is related with gestational diabetes mellitus (GDM).<h4>Methods</h4>Twenty-five GDM patients aged between 24 and 34 years and 24 healthy pregnant women aged between 22 and 33 years were included in this study. Health status of ... Read more >>

J Obstet Gynaecol Res (The journal of obstetrics and gynaecology research)
[2021, :]

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Isolated fallopian tubal torsion: Reproductive age case series.

Erkan Elçi, Sena Sayan, Gülhan Elçi, Güneş Koç,

<h4>Aim</h4>To present our experiences in isolated fallopian tubal torsion (IFTT) case series, which are difficult to diagnose, in light of the literature.<h4>Methods</h4>The data of the patients diagnosed with IFTT surgically in our tertiary hospital between 2018 and 2019 were evaluated.<h4>Results</h4>Abdominal lower quadrant pain was present in all nine cases. Abdominal ... Read more >>

J Obstet Gynaecol Res (The journal of obstetrics and gynaecology research)
[2021, :]

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May human epididymis 4 protein play a role in the etiopathogenesis of hemolysis, elevated liver enzymes and low platelets (HELLP) syndrome?

Taner Cam, Gamze Nur Cimilli Senocak, Nurinnisa Ozturk, Emsal Pınar Topdagi Yilmaz,

<h4>Aim</h4>Hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome is an extremely advanced form of preeclampsia. Currently, there is no parameter or marker to predict this syndrome; however, it is emphasized that vascular endothelial damage and abnormal immune responses can be the possible etiologies of HELLP syndrome. It is known ... Read more >>

J Obstet Gynaecol Res (The journal of obstetrics and gynaecology research)
[2021, :]

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Retrospective analysis of clinicopathological characteristics of 19 ovarian juvenile granulosa cell tumor cases.

Elijah Ndhlovu, Lili Liu, Jun Dai, Xiyuan Dong, Wen Zhang, Biao Chen,

<h4>Aim</h4>To describe the clinical and pathological characteristics, diagnosis, treatment, and outcomes of juvenile granulosa cell tumor (JGCT).<h4>Methods</h4>We retrospectively analyzed the data of 19 patients with histopathologically confirmed juvenile granulosa cell tumors treated in two medical centers in Wuhan city of China between 1999 and 2019.<h4>Results</h4>Totally, 19 patients were included during ... Read more >>

J Obstet Gynaecol Res (The journal of obstetrics and gynaecology research)
[2021, :]

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Hysterectomy and bilateral adnexectomy using transvaginal natural orifice transluminal endoscopic surgery: The role of multichannel abdominal PORT and vaginal support ring.

Junji Zhang, Yi Dai, Jinhua Leng, Lan Zhu, Jinghe Lang, Dawei Sun,

<h4>Background</h4>Although transvaginal natural orifice transluminal endoscopic surgery (NOTES) is gaining importance, knowledge on transvaginal NOTES procedures in gynecologic practice is limited.<h4>Objective</h4>We aimed at evaluating the feasibility and safety of performing hysterectomy and bilateral adnexectomy (or bilateral salpingectomy) via transvaginal NOTES using a self-developed multichannel abdominal port and vaginal support ring.<h4>Study ... Read more >>

J Obstet Gynaecol Res (The journal of obstetrics and gynaecology research)
[2021, :]

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Clinical management of chemotherapy for elderly gynecological cancer patients.

Yoshio Yoshida, Daisuke Inoue,

<h4>Aim</h4>Since there are no established guidelines for the treatment of gynecological cancer in the elderly, medical treatment policy is currently decided by discussion with patients and their families based on doctors' experiences, referring to data from nonelderly patients and healthy elderly patients. The aim of this review was to clarify ... Read more >>

J Obstet Gynaecol Res (The journal of obstetrics and gynaecology research)
[2021, :]

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Letter to "removable retropubic uterine compression suture for controlling postpartum hemorrhage": The latest, the best?

Shigeki Matsubara,

J Obstet Gynaecol Res (The journal of obstetrics and gynaecology research)
[2021, :]

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Clinicopathological characteristics and prognosis of uterine serous carcinoma: A SEER program analysis of 1016 cases.

Ying Han, Chongdong Liu,

<h4>Aim</h4>To identify the clinicopathological features and survival outcomes of uterine serous carcinoma (USC) and the prognostic factors influencing survival.<h4>Methods</h4>The retrospective, population-based cohort study enrolled patients with USC diagnosed between 2001 and 2015 for the Surveillance, Epidemiology, and End Results (SEER) program. Kaplan-Meier analysis was performed to identify survival outcomes, multivariable ... Read more >>

J Obstet Gynaecol Res (The journal of obstetrics and gynaecology research)
[2021, :]

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Expression of tissue factor and thrombomodulin in the placentas of pregnancies affected by early-onset and late-onset preeclampsia.

Paola Ayala-Ramírez, Tatiana Gámez, Derna L Castro-Pontón, Jaime Silva, Reggie García-Robles, Mercedes Olaya-C,

<h4>Aim</h4>To analyze the differential genetic expression and protein localization of thrombomodulin (THBD) and tissue factor (F3) in the placentas of pregnancies affected by preeclampsia.<h4>Methods</h4>We assessed the expression of THBD and F3 by immunohistochemistry and real-time polymerase chain reaction (PCR) in placentas from 20 PE cases: 10 early-onset PE placentas, 10 ... Read more >>

J Obstet Gynaecol Res (The journal of obstetrics and gynaecology research)
[2021, :]

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Erastin synergizes with cisplatin via ferroptosis to inhibit ovarian cancer growth in vitro and in vivo.

Qi Cheng, Lingjie Bao, Mingqing Li, Kaikai Chang, Xiaofang Yi,

<h4>Aim</h4>Cisplatin-based chemotherapy is the first-line treatment for ovarian cancer. However, acquired resistance to cisplatin treatment or serious side effects often occurs in ovarian cancer, and thus, there is an urgent need for effective and combined therapies to overcome such obstacles. In the present study, we aimed to uncover synergistic effects ... Read more >>

J Obstet Gynaecol Res (The journal of obstetrics and gynaecology research)
[2021, :]

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Survey of attitudes of individuals who underwent remote prenatal check-ups and consultations in response to the COVID-19 pandemic.

Kinuko Nakagawa, Takeshi Umazume, Michinori Mayama, Kentaro Chiba, Yoshihiro Saito, Kiwamu Noshiro, Mamoru Morikawa, Masanori Yoshino, Hidemichi Watari,

<h4>Aim</h4>Perinatal telemedicine efforts have commenced worldwide in response to the COVID-19 pandemic. As there have been no prior studies on the acceptance of telemedicine by pregnant women, we conducted this survey to investigate the same.<h4>Methods</h4>We conducted an anonymous questionnaire survey of pregnant women who underwent telemedicine check-ups from March 4 ... Read more >>

J Obstet Gynaecol Res (The journal of obstetrics and gynaecology research)
[2021, :]

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A case of cervical clear cell carcinoma with serous component.

Keiko Ebisawa, Takahiro Sugiyama, Makiko Itami, Yoshiaki Maru, Yoshitaka Hippo, Naotake Tanaka,

Cervical clear cell carcinoma (CCCC) is rare. This report describes the case of CCCC with a serous component. A 22-year-old woman presented with vaginal bleeding. A cervical tumor was discovered: pelvic magnetic resonance imaging revealed a tumor measuring 46 mm. Radical hysterectomy was performed based on the diagnosis of stage IB2 ... Read more >>

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[2021, :]

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