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Contrasting specific antibody response to BNT162b2 mRNA vaccination in SARS-CoV-2-naive and previously infected nursing home residents

Yong Chong, Naoki Tani, Takeyuki Goto, Akiko Yonekawa, Hideyuki Ikematsu, Nobuyuki Shimono, Yosuke Tanaka, Koichi Akashi,

J Infect (The Journal of infection)
[2021, :]

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Persistence at one year of neutralising antibodies after SARS-CoV-2 infection: Influence of initial severity and steroid use

Olivier Epaulard, Marlyse Buisson, Benjamin Nemoz, Marion Le Maréchal, Nicolas Terzi, Jean-François Payen, Marie Froidure, Myriam Blanc, Anne-Laure Mounayar, Fanny Quénard, Isabelle Pierre, Patricia Pavese, Raphaele Germi, Laurence Grossi, Sylvie Larrat, Pascal Poignard, Julien Lupo,

J Infect (The Journal of infection)
[2021, :]

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SARS-CoV-2 vaccine breakthrough infection following a previous infection in a healthcare worker

Aayush Gupta, Rahul C. Bhoyar, Shahzad Mirza, Bani Jolly, Vigneshwar Senthivel, Afra Shamnath, Mohit Kumar Divakar, Mohamed Imran, Vishu Gupta, Srashti Jyoti Agrawal, Sahjid Mukhida, Sridhar Sivasubbu, Vinod Scaria,

J Infect (The Journal of infection)
[2021, :]

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Re-emergence of Highly Pathogenic Avian Influenza A(H5N8) Virus In Domestic Goose, China.

Jinyue Guo, Hai Yu, Congying Wang, Sheng Yuan, Hailiang Sun, Jing Yang, Qing Cheng, Kaijian Luo, Yong Li, Zhili Li, Quan Liu, Shujian Huang, Feng Wen,

J Infect (The Journal of infection)
[2021, :]

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Suspected reinfections of SARS-COV-2 in Khyber Pakhtunkhwa, Pakistan - analysis of province-wide testing database.

Habab Ali Ahmad, Haleema Khan, Muhammad Shahzad, Zia Ul Haq, Steve Harake, Yasar Mehmood Yousafzai,

J Infect (The Journal of infection)
[2021, :]

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Real-time whole genome sequencing direct diagnosis of Streptococcus pneumoniae meningitis: a case report.

M Morsli, Q Kerharo, S Amrane, P Parola, P E Fournier, M Drancourt,

J Infect (The Journal of infection)
[2021, :]

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A prolonged, nationwide measles outbreak despite very high vaccination coverage in Israel, 2018-19.

Emilia Anis, Eric J Haas, Viki Indenbaum, Shephard Roee Singer, Bruce Warshavsky, Shmuel Rishpon, Manfred S Green, Ella Mendelson, Itamar Grotto, Ehud Kaliner, Siegal Sadetzki,

<h4>Background</h4>. A major, prolonged measles outbreak occurred in Israel during 2018-19, despite vaccination coverage rates of 97% and 96% for the first and second doses, respectively, of measles containing vaccine (MCV).<h4>Aim</h4>. To study the causes and patterns of the outbreak through analysis of the epidemiological data, review the control measures ... Read more >>

J Infect (The Journal of infection)
[2021, :]

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Characterization of key amino acid substitutions and dynamics of the influenza virus H3N2 hemagglutinin.

Maggie Haitian Wang, Jingzhi Lou, Lirong Cao, Shi Zhao, Renee Wy Chan, Paul Ks Chan, Martin Chi-Wai Chan, Marc Kc Chong, William Kk Wu, Yuchen Wei, Haoyang Zhang, Benny Cy Zee, Eng-Kiong Yeoh,

The annual epidemics of seasonal influenza is partly attributed to the continued virus evolution. It is challenging to evaluate the effect of influenza virus mutations on evading population immunity. In this study, we introduce a novel statistical and computational approach to measure the dynamic molecular determinants underlying epidemics using effective ... Read more >>

J Infect (The Journal of infection)
[2021, :]

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Impact of a 24/7 multiplex-PCR on the management of patients with confirmed viral meningitis.

Gauthier Péan de Ponfilly, Anthony Chauvin, Maud Salmona, Hanaa Benmansour, Béatrice Bercot, Francois Camelena, Virginie Courbin, Xavier Eyer, Emmanuel Lecorche, Faïza Mougari, Anne-Lise Munier, Eric Revue, Jérôme LeGoff, Emmanuelle Cambau, Hervé Jacquier,

<h4>Objectives</h4>The relevance of syndromic multiplex-PCR for the etiological diagnosis of meningitis or meningoencephalitis is still a matter of debate. Here, we studied the impact of a 24/7 multiplex-PCR on the management of patients consulting in the emergency department for suspicion of community-acquired meningitis.<h4>Methods</h4>We conducted a single-center retrospective study at the ... Read more >>

J Infect (The Journal of infection)
[2021, :]

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War-torn Afghanistan - potential risk to the polio eradication efforts: A call for global concern!

Usman Ayub Awan, Muhammad Wasif Malik, Haroon Ahmed, Usman Hassan, Abdul Sami Khan, Shaarif Bashir, Muhammad Sohail Afzal,

J Infect (The Journal of infection)
[2021, :]

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Clinical predictors of outcome in patients with infective endocarditis receiving outpatient parenteral antibiotic therapy (OPAT).

Oyewole Chris Durojaiye, Robin Morgan, Naziha Chelaghma, Evangelos I Kritsotakis,

<h4>Objectives</h4>Outpatient parenteral antimicrobial therapy (OPAT) is increasingly used to treat infective endocarditis (IE) with documented success. This study aims to identify risk factors for treatment failure and poor outcomes in patients with IE treated through OPAT.<h4>Methods</h4>We conducted a retrospective analysis of all episodes of IE treated over 13 years (September ... Read more >>

J Infect (The Journal of infection)
[2021, :]

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Genomic analysis of maternal carriage of group B Streptococcus and transmission routes of neonatal sepsis.

Chien-Chung Lee, Ye Feng, Chyi-Liang Chen, Yuan-Ming Yeh, Mei-Hua Hsu, Wan-Ting Liao, Ying-Li Zhou, Petrus Tang, Cheng-Hsun Chiu,

J Infect (The Journal of infection)
[2021, :]

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The Alpha variant was not associated with excess nosocomial SARS-CoV-2 infection in a multi-centre UK hospital study.

Florencia A T Boshier, Cristina Venturini, Oliver Stirrup, José Afonso Guerra-Assunção, Adela Alcolea-Medina, Angela H Becket, Matthew Byott, Themoula Charalampous, Ana da Silva Filipe, Dan Frampton, Sharon Glaysher, Tabassum Khan, Raghavendran Kulasegara-Shylini, Beatrix Kele, Irene M Monahan, Guy Mollett, Matthew Parker, Emanuela Pelosi, Paul Randell, Sunando Roy, Joshua F Taylor, Sophie J Weller, Eleri Wilson-Davies, Phillip Wade, Rachel Williams, Andrew J Copas, Teresa Cutino-Moguel, Nick Freemantle, Andrew C Hayward, Alison Holmes, Joseph Hughes, Tabitha W Mahungu, Gaia Nebbia, Eleni Nastouli, David G Partridge, Cassie F Pope, James R Price, Samuel C Robson, Kordo Saeed, Gee Yen Shin, Thushan I de Silva, Luke B Snell, Emma C Thomson, Adam A Witney, Judith Breuer, ,

<h4>Objectives</h4>Recently emerging SARS-CoV-2 variants have been associated with an increased rate of transmission within the community. We sought to determine whether this also resulted in increased transmission within hospitals.<h4>Methods</h4>We collected viral sequences and epidemiological data of patients with community and healthcare associated SARS-CoV-2 infections, sampled from 16th November 2020 to ... Read more >>

J Infect (The Journal of infection)
[2021, :]

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"Mortality in Staphylococcus aureus bacteraemia remains high despite adherence to quality indicators: secondary analysis of a prospective cohort study ".

Rein Willekens, Mireia Puig-Asensio, Paula Suanzes, Nuria Fernández-Hidalgo, Maria N Larrosa, Juan J González-López, Dolors Rodríguez-Pardo, Carles Pigrau, Benito Almirante,

<h4>Objectives</h4>To evaluate the association between compliance with previously published quality indicators (QIs) for the management of Staphylococcus aureus bacteraemia (SAB) and 30-day mortality.<h4>Methods</h4>We conducted a post hoc analysis of all adult patients with SAB who were hospitalized at a Spanish university hospital between 2013 and 2018. We evaluated the compliance ... Read more >>

J Infect (The Journal of infection)
[2021, :]

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Environmental dynamics of hospital microbiome upon transfer from a major hospital to a new facility.

Anushia Ashokan, Jocelyn M Choo, Steven L Taylor, Diana Lagana, David R Shaw, Morgyn S Warner, Steve L Wesselingh, Geraint B Rogers,

<h4>Background</h4>Infection control is critical to safe hospital care. However, how bacteria within nosocomial environments relate to space utilisation and occupancy remains poorly understood. Our aim was to characterise the hospital microbiome in the context of the closure of a tertiary hospital and the opening of a new facility.<h4>Methods</h4>Environmental swabs were ... Read more >>

J Infect (The Journal of infection)
[2021, :]

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Novel biomarkers for the early prediction of pediatric cystic echinococcosis post-surgical outcomes.

Eya Ben Salah, Coralie Barrera, Wahiba Sakly, Sana Mosbahi, Thierry Balliau, Nathalie Franche, Bruno Gottstein, Sabrine Ben Youssef, Mongi Mekki, Hamouda Babbaa, Laurence Millon,

<h4>Objective</h4>This study aims to search for reliable serological biomarkers allowing the early prediction of cystic echinococcosis (CE) post-operative outcomes.<h4>Methods</h4>We applied immunoprecipitation (IP) of Echinococcus granulosus protoscolex antigens with pediatric CE patients' plasma collected at 1-month and 1-year post-surgery, followed by Liquid Chromatography with tandem mass spectrometry (LC-MS/MS). We compared IP ... Read more >>

J Infect (The Journal of infection)
[2021, :]

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Serological profile of first SARS-CoV-2 reinfection cases detected within the SIREN study.

A Atti, M Ferrari, J Castillo-Olivares, E J M Monk, R Gopal, M Patel, K Hoschler, M J Cole, A Semper, J Hewson, A D Otter, S Foulkes, J Islam, M Mirfenderesky, S Jain, J Murira, C Favager, E Nastouli, M A Chand, C S Brown, J L Heeney, T Brooks, V J Hall, S Hopkins, M Zambon,

<h4>Objectives</h4>To describe the serological profile of first two SARS-CoV-2 confirmed reinfections in the national healthcare worker cohort study SARS-CoV-2 Immunity and Reinfection Evaluation (SIREN) and potentially identify correlates of protection against reinfection.<h4>Methods</h4>In addition to routine testing within the SIREN study, viral culture, sequencing and phylogenetic analysis were performed. Total antibody ... Read more >>

J Infect (The Journal of infection)
[2021, :]

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Metagenomic sequencing with spiked-in internal control to monitor cellularity and diagnosis of pneumonia.

Hua Zhou, Chuan Ouyang, Xu Han, Lisha Shen, Jian Ye, Zhixian Fang, Wenyu Chen, Aifeng Chen, Qiang Ma, Maohong Hua, Junfei Zhu, Xiaomai Wu, Xuemei Lin, Yuexiang Shui, Changsheng Zhou, Kai Fang, Junwei Du, Zhihui Huang, Gang Wang, Qun Lv, Weina Huang, Jun Wang, Xiaoting Hua, Jianying Zhou, Chao Liu, Yunsong Yu,

J Infect (The Journal of infection)
[2021, :]

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Decreasing proportion of extended-spectrum beta-lactamase among E. coli infections during the COVID-19 pandemic in France.

Olivier Lemenand, Thomas Coeffic, Sonia Thibaut, Melanie Colomb Cotinat, Jocelyne Caillon, Gabriel Birgand, ,

<h4>Objectives</h4>We investigated the impact of the COVID-19 and national pandemic response on the epidemiology of Extended Spectrum Beta-Lactamase producing E. coli (ESBL-E.coli) in France.<h4>Methods</h4>Individual microbiology records from clinical laboratories were analyzed between 1 January 2019 to 31 December 2020. The ESBL-E.coli rates from clinical samples of patients in primary care ... Read more >>

J Infect (The Journal of infection)
[2021, :]

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Host inflammatory response is the major marker of severe Respiratory Syncytial Virus infection in older adults.

G Lui, C K Wong, M Chan, K C Chong, R Wong, I Chu, M Zhang, T Li, Dsc Hui, N Lee, Pks Chan,

<h4>Objectives</h4>We aim to study the viral kinetics and host inflammatory response of RSV infection in older adults, and their correlation with disease severity.<h4>Methods</h4>We performed a prospective observational study in adults with RSV infection. We serially collected nasal-throat swabs for quantification of RSV-A and RSV-B viral load, and peripheral blood samples ... Read more >>

J Infect (The Journal of infection)
[2021, :]

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Multicentric evaluation of a 3D-printed simulator for COVID- 19 nasopharyngeal swab collection in testing centers.

Lise Lecointre, Aïna Venkatasamy, Mégane Wehr, Antoine Koch, Axel Sananes, Christian Debry, Massimo Lodi, Nicolas Sananes,

J Infect (The Journal of infection)
[2021, :]

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Decreasing humoral response among healthcare workers up to 4 months after two doses of BNT162b2 vaccine.

Valentine Marie Ferré, Samuel Lebourgeois, Reyene Menidjel, Gilles Collin, Houssem Redha Chenane, Manuella Onambele Guindi, Yazdan Yazdanpanah, Jean-François Timsit, Charlotte Charpentier, Diane Descamps, Nadhira Fidouh, Benoit Visseaux,

J Infect (The Journal of infection)
[2021, :]

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A novel droplet digital polymerase chain reaction for diagnosis of Pneumocystis pneumonia (PCP)-a clinical performance study and survey of sulfamethoxazole-trimethoprim resistant mutations.

Anupop Jitmuang, Anapat Nititammaluk, Thitaya Boonsong, Patsharaporn Techasintana Sarasombath, Suree Sompradeekul, Methee Chayakulkeeree,

Objectives To determine the performance of droplet digital polymerase chain reaction (ddPCR) assays in diagnosing Pneumocystis pneumonia (PCP), and to survey the sulfamethoxazole-trimethoprim (SMX-TMP) resistant mutations in our PCP cohort. Methods A prospective study was conducted from January 2017 to June 2018. Adult immunocompromised subjects with pneumonia were enrolled. Bronchoalveolar ... Read more >>

J Infect (The Journal of infection)
[2021, :]

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Risk factors associated with bloodstream infections among critically ill patients with COVID-19.

Tim McMillan, Conor Jones, Cavan J O'Connor, Daniel Nolan, Xin Hui S Chan, Jayne Ellis, Clare Thakker, Katharina Kranzer, Neil Rh Stone, Mervyn Singer, A Peter R Wilson, Nishkantha Arulkumaran,

J Infect (The Journal of infection)
[2021, :]

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Antibody titers and protection against a SARS-CoV-2 infection.

Chloé Dimeglio, Fabrice Herin, Guillaume Martin-Blondel, Marcel Miedougé, Jacques Izopet,

J Infect (The Journal of infection)
[2021, :]

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