Full Text Journal Articles in
Journal J Gynecol Oncol

Advertisement

Find full text journal articles






A single-arm phase II study of olaparib maintenance with pembrolizumab and bevacizumab in BRCA non-mutated patients with platinum-sensitive recurrent ovarian cancer (OPEB-01).

Yong Jae Lee, Myong Cheol Lim, Byoung Gie Kim, Natalie Yl Ngoi, Chel Hun Choi, Sang Yoon Park, David Sp Tan, Yunjung Go, Jung Yun Lee,

<h4>Background</h4>The optimal treatment of <i>BRCA</i> wild-type patients with platinum-sensitive recurrent ovarian cancer remains unknown. Recently, there is an increase in the evidence to support the role of the combination of a poly(adenosine diphosphate-ribose) polymerase inhibitor, anti-angiogenic agents, and immunotherapy as maintenance therapy in <i>BRCA</i> wild-type patients with platinum-sensitive recurrence. We ... Read more >>

J Gynecol Oncol (Journal of gynecologic oncology)
[2021, 32(2):e31]

Cited: 0 times

View full text PDF listing >>



Identification of an immune-related risk signature and nomogram predicting the overall survival in patients with endometrial cancer.

Yuan Cheng, Xingchen Li, Yibo Dai, Yangyang Dong, Xiao Yang, Jianliu Wang,

<h4>Objective</h4>Aimed to construct an immune-related risk signature and nomogram predicting endometrial cancer (EC) prognosis.<h4>Methods</h4>An immune-related risk signature in EC was constructed using the least absolute shrinkage and selection operator regression analysis based on The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases. A nomogram integrating the immune-related genes ... Read more >>

J Gynecol Oncol (Journal of gynecologic oncology)
[2021, 32(3):e30]

Cited: 0 times

View full text PDF listing >>



Advertisement

Cost-effectiveness of olaparib versus routine surveillance in the maintenance setting for patients with BRCA-mutated advanced ovarian cancer after response to first-line platinum-based chemotherapy in Singapore.

David Sp Tan, Jack Junjie Chan, Robert Hettle, Wrik Ghosh, Amrita Viswambaram, Cindy Chen Yu,

<h4>Objective</h4>To evaluate the cost-effectiveness of olaparib as a maintenance treatment versus routine surveillance (RS) in patients with <i>BRCA</i> mutated (<i>BRCA</i>m) advanced ovarian cancer (OC) following response to first-line platinum-based chemotherapy in Singapore.<h4>Methods</h4>A 4-health state partitioned survival model was developed to simulate the lifetime (50 years) incremental cost-effectiveness ratio (ICER) of ... Read more >>

J Gynecol Oncol (Journal of gynecologic oncology)
[2021, 32(2):e27]

Cited: 0 times

View full text PDF listing >>



Recurrence risk factors in stage IA grade 1 endometrial cancer.

Chika Nwachukwu, Mana Baskovic, Rie Von Eyben, Dylann Fujimoto, Stephanie Giaretta, Diana English, Elizabeth Kidd,

<h4>Objectives</h4>Patients with early-stage endometrial cancers (EC) with disease recurrences have worse survival outcomes. The purpose of this study was to identify clinical and pathologic factors that predict for all recurrences in stage IA grade 1 (IAG1) EC.<h4>Methods</h4>Records from patients diagnosed with EC were retrospectively reviewed. Baseline characteristics of 222 patients ... Read more >>

J Gynecol Oncol (Journal of gynecologic oncology)
[2021, 32(2):e22]

Cited: 1 time

View full text PDF listing >>



Implementation and evaluation of a novel subspecialty society fellows robotic surgical course: the SGO minimally invasive academy surgical curriculum.

Teresa K L Boitano, Haller J Smith, Joshua G Cohen, Emma C Rossi, Kenneth H Kim,

<h4>Objective</h4>To evaluate the utility of a society-based robotic surgery training program for fellows in gynecologic oncology.<h4>Methods</h4>All participants underwent a 2-day robotic surgery training course between 2015-2017. The course included interactive didactic sessions with video, dry labs, and robotic cadaver labs. The labs encompassed a wide range of subject matter including ... Read more >>

J Gynecol Oncol (Journal of gynecologic oncology)
[2021, 32(2):e26]

Cited: 1 time

View full text PDF listing >>



Hospital volume-outcome relationship in vulvar cancer treatment: a Japanese Gynecologic Oncology Group study.

Koji Matsuo, Shin Nishio, Shinya Matsuzaki, Hiroko Machida, Mikio Mikami,

J Gynecol Oncol (Journal of gynecologic oncology)
[2021, 32(2):e24]

Cited: 0 times

View full text PDF listing >>



Phase 2 single-arm study on the safety of maintenance niraparib in Japanese patients with platinum-sensitive relapsed ovarian cancer.

Kazuhiro Takehara, Takashi Matsumoto, Junzo Hamanishi, Kosei Hasegawa, Motoki Matsuura, Kiyonori Miura, Shoji Nagao, Hidekatsu Nakai, Naotake Tanaka, Hideki Tokunaga, Kimio Ushijima, Hidemichi Watari, Yoshihito Yokoyama, Yoichi Kase, Shuuji Sumino, Ajit Suri, Hiroaki Itamochi, Nobuhiro Takeshima,

<h4>Objective</h4>The primary objective of this study was to evaluate the safety of niraparib 300 mg/day in Japanese patients with platinum-sensitive, relapsed ovarian cancer in a maintenance setting.<h4>Methods</h4>Phase 2, multicenter, open-label, single-arm study enrolled Japanese patients with platinum-sensitive, relapsed ovarian cancer who had received ≥2 platinum-based regimens. The primary endpoint (incidence ... Read more >>

J Gynecol Oncol (Journal of gynecologic oncology)
[2021, 32(2):e21]

Cited: 1 time

View full text PDF listing >>



Substantial lymph-vascular space invasion (LVSI) as predictor of distant relapse and poor prognosis in low-risk early-stage endometrial cancer.

Lucia Tortorella, Stefano Restaino, Gian Franco Zannoni, Giuseppe Vizzielli, Vito Chiantera, Serena Cappuccio, Alessandro Gioè, Eleonora La Fera, Giorgia Dinoi, Giuseppe Angelico, Giovanni Scambia, Francesco Fanfani,

<h4>Objective</h4>The aim of this study is to analyze the prognostic role of lymph-vascular space invasion (LVSI), evaluated in a semi-quantitative fashion on prognosis of early stage, low risk endometrial cancer (EC).<h4>Methods</h4>We enrolled patients who underwent surgery for endometrial cancer between 2003 and 2018 in two referral cancer center. All patients ... Read more >>

J Gynecol Oncol (Journal of gynecologic oncology)
[2021, 32(2):e11]

Cited: 1 time

View full text PDF listing >>



Lymphadenectomy issues in endometrial cancer.

Yosuke Konno, Hiroshi Asano, Ayumi Shikama, Daisuke Aoki, Michihiro Tanikawa, Akinori Oki, Koji Horie, Akira Mitsuhashi, Akira Kikuchi, Hideki Tokunaga, Yasuhisa Terao, Toyomi Satoh, Kimio Ushijima, Mitsuya Ishikawa, Nobuo Yaegashi, Hidemichi Watari,

<h4>Objectives</h4>This review aims to introduce preoperative scoring systems to predict lymph node metastasis (LNM) and ongoing clinical trials to investigate the therapeutic role of lymphadenectomy for endometrial cancer.<h4>Methods</h4>We summarized previous reports on the preoperative prediction models for LNM and evaluated their validity to omit lymphadenectomy in our recent cohorts. Next, ... Read more >>

J Gynecol Oncol (Journal of gynecologic oncology)
[2021, 32(2):e25]

Cited: 0 times

View full text PDF listing >>



Peripheral blood BRCA1 methylation profiling to predict familial ovarian cancer.

Yuyeon Jung, Sooyoung Hur, JingJing Liu, Sanha Lee, Byung Soo Kang, Myungshin Kim, Youn Jin Choi,

<h4>Objective</h4>Familial cancer appears at a young age and its incidence is increasing. About 12% of familial ovarian cancer cases are associated with <i>BRCA1/2</i> mutations (BRCAm). In this study, we investigated <i>BRCA1</i> methylation may predict ovarian cancer in those with a family history of cancer (FHC) but without <i>BRCA1/2</i> mutations (BRCAwt).<h4>Methods</h4>Using ... Read more >>

J Gynecol Oncol (Journal of gynecologic oncology)
[2021, 32(2):e23]

Cited: 1 time

View full text PDF listing >>



Comparison between laparoscopic and abdominal radical hysterectomy for stage IB1 and tumor size <2 cm cervical cancer with visible or invisible tumors: a multicentre retrospective study.

Pengfei Li, Lan Chen, Yan Ni, Jiaqi Liu, Donglin Li, Jianxin Guo, Zhihua Liu, Shuangling Jin, Yan Xu, Zhiqiang Li, Lu Wang, Xiaonong Bin, Jinghe Lang, Ping Liu, Chunlin Chen,

<h4>Objective</h4>To compare 5-year disease-free survival (DFS) and overall survival (OS) rates of laparoscopic radical hysterectomy (LRH) and abdominal radical hysterectomy (ARH) for stage IB1 and tumor size <2 cm with visible or invisible tumors.<h4>Methods</h4>We retrospectively compared the oncological outcomes of 1,484 cervical cancer patients with IB1 and tumor size <2 ... Read more >>

J Gynecol Oncol (Journal of gynecologic oncology)
[2021, 32(2):e17]

Cited: 1 time

View full text PDF listing >>



The current status of laparoscopic and robotic para-aortic lymphadenectomy in gynecologic cancer surgery.

Thomas Ind,

J Gynecol Oncol (Journal of gynecologic oncology)
[2021, 32(1):e28]

Cited: 0 times

View full text PDF listing >>



Trend analysis of process quality indicators for the Korean National Cervical Cancer Screening Program from 2005 to 2013.

Cam Nhung Bui, Eunji Choi, Mina Suh, Jae Kwan Jun, Kyu Won Jung, Myong Cheol Lim, Kui Son Choi,

<h4>Objective</h4>This study sought to examine changes in trends for quality indicators of the population-based Korean National Cancer Screening Program (KNCSP) for cervical cancer from years 2005 to 2013.<h4>Methods</h4>Our study data were derived from the KNCSP database. Cervical cancer diagnosis information was ascertained through linkage with the Korean National Cancer Registry ... Read more >>

J Gynecol Oncol (Journal of gynecologic oncology)
[2021, 32(1):e14]

Cited: 0 times

View full text PDF listing >>



Time for enhancing government-led primary prevention of cervical cancer.

Kyung Jin Min, Dong Hoon Suh, Tsukasa Baba, Xiaojun Chen, Jae Weon Kim, Yusuke Kobayashi, Janice Kwon, Myong Cheol Lim, Jung Yun Lee, Satoru Nagase, Jeong Yeol Park, Siriwan Tangjitgamol, Hidemichi Watari,

J Gynecol Oncol (Journal of gynecologic oncology)
[2021, 32(1):e12]

Cited: 0 times

View full text PDF listing >>



Ovarian cancer risk score predicts chemo-response and outcome in epithelial ovarian carcinoma patients.

Hsiao Yun Lu, Yi Jou Tai, Yu Li Chen, Ying Cheng Chiang, Heng Cheng Hsu, Wen Fang Cheng,

<h4>Objective</h4>Cytoreductive surgery followed by adjuvant chemotherapy is a standard frontline treatment for epithelial ovarian cancer (EOC). We aimed to develop an ovarian cancer risk score (OVRS) based on the expression of 10 ovarian-cancer-related genes to predict the chemoresistance, and outcomes of EOC patients.<h4>Methods</h4>We designed a case-control study with total 149 ... Read more >>

J Gynecol Oncol (Journal of gynecologic oncology)
[2021, 32(2):e18]

Cited: 1 time

View full text PDF listing >>



Radiotherapy combined with chemotherapy increases the risk of herpes zoster in patients with gynecological cancers: a nationwide cohort study.

Peng Yi Lee, Jung Nien Lai, Shang Wen Chen, Ying Chun Lin, Lu Ting Chiu, Yu Ting Wei,

<h4>Objective</h4>This study aimed to determine the effect of radiotherapy (RT) on the risk of herpes zoster (HZ) in patients with gynecological cancers via a nationwide population-based study.<h4>Methods</h4>Based on patient data obtained from the National Health Insurance Research Database, 1928 gynecological cancer patients were identified with 1:1 matching for RT and ... Read more >>

J Gynecol Oncol (Journal of gynecologic oncology)
[2021, 32(2):e13]

Cited: 1 time

View full text PDF listing >>



Phase 2 single-arm study on the efficacy and safety of niraparib in Japanese patients with heavily pretreated, homologous recombination-deficient ovarian cancer.

Aikou Okamoto, Eiji Kondo, Toshiaki Nakamura, Satoshi Yanagida, Junzo Hamanishi, Kenichi Harano, Kosei Hasegawa, Takeshi Hirasawa, Kensuke Hori, Shinichi Komiyama, Motoki Matsuura, Hidekatsu Nakai, Hiroko Nakamura, Jun Sakata, Tsutomu Tabata, Kazuhiro Takehara, Munetaka Takekuma, Yoshihito Yokoyama, Yoichi Kase, Shuuji Sumino, Junpei Soeda, Ajit Suri, Daisuke Aoki, Toru Sugiyama,

<h4>Objective</h4>To evaluate the efficacy and safety of niraparib in Japanese women with heavily pretreated ovarian cancer.<h4>Methods</h4>This Phase 2 open-label, single-arm study enrolled Japanese women with homologous recombination deficiency-positive relapsed, high-grade serous ovarian, fallopian tube, or primary peritoneal cancer who had completed 3-4 lines of therapy. The starting dose of niraparib ... Read more >>

J Gynecol Oncol (Journal of gynecologic oncology)
[2021, 32(2):e16]

Cited: 1 time

View full text PDF listing >>



The role of secondary cytoreduction in recurrent, platinum-sensitive ovarian cancer: what do the trials tell us?

Robert L Coleman,

J Gynecol Oncol (Journal of gynecologic oncology)
[2021, 32(1):e20]

Cited: 0 times

View full text PDF listing >>



Why was GOG-0213 a negative trial?

Sarah Ehmann, Oliver Zivanovic, Dennis S Chi,

J Gynecol Oncol (Journal of gynecologic oncology)
[2021, 32(1):e19]

Cited: 0 times

View full text PDF listing >>



Safety and efficacy of 3D-printed templates assisted CT-guided radioactive iodine-125 seed implantation for the treatment of recurrent cervical carcinoma after external beam radiotherapy.

Yanhao Liu, Ping Jiang, Haichen Zhang, Junjie Wang,

<h4>Objective</h4>To investigate the safety and efficacy of 3-dimensional (3D) printing non-coplanar templates (PNCT) assisted computer tomography (CT) guided radioactive <sup>125</sup>I seed implantation (RISI) for the treatment of recurrent cervical carcinoma (RCC) after external beam radiotherapy (EBRT).<h4>Methods</h4>A total of 103 patients with inoperable post-EBRT RCC were included in this retrospective study. ... Read more >>

J Gynecol Oncol (Journal of gynecologic oncology)
[2021, 32(2):e15]

Cited: 1 time

View full text PDF listing >>



Total laparoscopic vs. conventional open abdominal nerve-sparing radical hysterectomy: clinical, surgical, oncological and functional outcomes in 301 patients with cervical cancer.

Marcello Ceccaroni, Giovanni Roviglione, Mario Malzoni, Francesco Cosentino, Emanuela Spagnolo, Roberto Clarizia, Paolo Casadio, Renato Seracchioli, Fabio Ghezzi, Daniele Mautone, Francesco Bruni, Stefano Uccella,

<h4>Objective</h4>Total laparoscopic nerve-sparing radical hysterectomy (TL-NSRH) has been considered a promising approach, however, surgical, clinical, oncological and functional outcomes have not been systematically addressed. We present a large retrospective multi-center experience comparing TL-NSRH vs. open abdominal NSRH (OA-NSRH) for early and locally-advanced cervical cancer, with particular emphasis on post-surgical pelvic ... Read more >>

J Gynecol Oncol (Journal of gynecologic oncology)
[2021, 32(1):e10]

Cited: 0 times

View full text PDF listing >>



Randomized phase III trial comparing pegylated liposomal doxorubicin (PLD) at 50 mg/m² versus 40 mg/m² in patients with platinum-refractory and -resistant ovarian carcinoma: the JGOG 3018 Trial.

Takashi Motohashi, Akira Yabuno, Hiroshi Michimae, Tetsuro Ohishi, Miwa Nonaka, Masashi Takano, Shin Nishio, Hiroyuki Fujiwara, Keiichi Fujiwara, Eiji Kondo, Toru Sugiyama, Tsutomu Tabata,

<h4>Objective</h4>The standard dose for pegylated liposomal doxorubicin (PLD) is 50 mg/m² every 4 weeks. While 40 mg/m² has recently been used in clinical practice, evidence supporting this use remains lacking.<h4>Methods</h4>This phase III randomized, non-inferiority study compared progression-free survival (PFS) for patients with platinum-resistant ovarian carcinoma between an experimental arm (40 ... Read more >>

J Gynecol Oncol (Journal of gynecologic oncology)
[2021, 32(1):e9]

Cited: 0 times

View full text PDF listing >>



Comments on: Fertility-sparing treatment for intramucous, moderately differentiated, endometrioid endometrial cancer: a Gynecologic Cancer Inter-Group (GCIG) study.

Jeong Yeol Park,

J Gynecol Oncol (Journal of gynecologic oncology)
[2020, 31(6):e96]

Cited: 0 times

View full text PDF listing >>



High mobility group box 3 promotes cervical cancer proliferation by regulating Wnt/β-catenin pathway.

Shichao Zhuang, Xiaohui Yu, Ming Lu, Yujiao Li, Ning Ding, Yumei Ding,

<h4>Objective</h4>High mobility group box 3 (HMGB3) plays an important role in the development of various cancer. This study aims to explore whether HMGB3 regulates cervical cancer (CC) progression and elucidate the underlying mechanism.<h4>Methods</h4>HMGB3 expression in clinical patients' tumor samples were determined by real-time quantitative polymerase chain reaction (qRT-PCR) and western ... Read more >>

J Gynecol Oncol (Journal of gynecologic oncology)
[2020, 31(6):e91]

Cited: 0 times

View full text PDF listing >>



Uterine clear cell carcinoma risk in White versus non-White US subpopulations: does race matter?

Stephanie Chow, Deanna Wong, Cheng I Liao, Amandeep Mann, Chunqiao Tian, Kathleen M Darcy, John K Chan,

<h4>Objective</h4>To determine incidence rates of uterine clear cell carcinoma among non-White US subpopulations.<h4>Methods</h4>Data from the United States Cancer Statistics and National Cancer Database from 2004 to 2016 were analyzed using descriptive statistics.<h4>Results</h4>A total of 488,811 women were diagnosed with uterine cancer from 2004-2016. Of these, 73.3% were endometrioid, 6.6% were ... Read more >>

J Gynecol Oncol (Journal of gynecologic oncology)
[2020, 31(6):e81]

Cited: 0 times

View full text PDF listing >>



Advertisement

Disclaimer
0.9689 s