Full Text Journal Articles in
Journal J Am Chem Soc

Advertisement

Find full text journal articles






B,N-Embedded Double Hetero[7]helicenes with Strong Chiroptical Responses in the Visible Light Region.

Ji-Kun Li, Xing-Yu Chen, Yun-Long Guo, Xin-Chang Wang, Andrew C-H Sue, Xiao-Yu Cao, Xiao-Ye Wang,

The development of helicene molecules with significant chiroptical responses covering a broad range of the visible spectrum is highly desirable for chiral optoelectronic applications; however, their absorption dissymmetry factors (gabs) have been mostly lower than 0.01. In this work, we report unprecedented B,N-embedded double hetero[7]helicenes with nonbonded B and N ... Read more >>

J Am Chem Soc (Journal of the American Chemical Society)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Theory and Experiment Demonstrate that Sb(V)-Promoted Methane C-H Activation and Functionalization Outcompete Superacid Protonolysis in Sulfuric Acid.

Shu-Sen Chen, Anjaneyulu Koppaka, Roy A Periana, Daniel H Ess,

Sb(V) in strong Brønsted acid solvents is traditionally assumed to react with light alkanes through superacid protonolysis, which results in carbocation intermediates, H2, and carbon oligomerization. In contrast to this general assumption, our density functional theory (DFT) calculations revealed an accessible barrier for C-H activation between methane and Sb(V) in ... Read more >>

J Am Chem Soc (Journal of the American Chemical Society)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Advertisement

Quantum Dot-Sensitized Photoreduction of CO2 in Water with Turnover Number > 80,000.

Francesca Arcudi, Luka Đorđević, Benjamin Nagasing, Samuel I Stupp, Emily A Weiss,

Climate change and global energy demands motivate the search for sustainable transformations of carbon dioxide (CO2) to storable liquid fuels. Photocatalysis is a pathway for direct conversion of CO2 to CO, one step within light-powered reaction networks that could, if efficient enough, transform the solar energy conversion landscape. To date, ... Read more >>

J Am Chem Soc (Journal of the American Chemical Society)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Chemical Synthesis of a Full-Length G-Protein-Coupled Receptor β2-Adrenergic Receptor with Defined Modification Patterns at the C-Terminus.

Yulei Li, Jie Heng, Demeng Sun, Baochang Zhang, Xin Zhang, Yupeng Zheng, Wei-Wei Shi, Tong-Yue Wang, Jiu-Yi Li, Xiaoou Sun, Xiangyu Liu, Ji-Shen Zheng, Brian K Kobilka, Lei Liu,

The β2-adrenergic receptor (β2AR) is a G-protein-coupled receptor (GPCR) that responds to the hormone adrenaline and is an important drug target in the context of respiratory diseases, including asthma. β2AR function can be regulated by post-translational modifications such as phosphorylation and ubiquitination at the C-terminus, but access to the full-length ... Read more >>

J Am Chem Soc (Journal of the American Chemical Society)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Synthesis of Cyclopentenones with C4-Quaternary Stereocenters via Stereospecific [3,3]-Sigmatropic Rearrangement and Applications in Total Synthesis of Sesquiterpenoids.

Weiping Zhou, Arnaud Voituriez,

A cationic gold(I)-catalyzed asymmetric [3,3]-sigmatropic rearrangement of sulfonium leads after cyclization to cyclopentenones with a C4-quaternary stereocenter. Starting with simple vinyl sulfoxides and propargyl silane, numerous compounds were isolated with moderate to good yields and excellent enantiomeric excesses (26 examples). The application of this simple methodology allowed the efficient total ... Read more >>

J Am Chem Soc (Journal of the American Chemical Society)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Experimental Evidence of Long-Lived Electric Fields of Ionic Liquid Bilayers.

Mattia Belotti, Xin Lyu, Longkun Xu, Peter Halat, Nadim Darwish, Debbie S Silvester, Ching Goh, Ekaterina I Izgorodina, Michelle L Coote, Simone Ciampi,

Herein we demonstrate that ionic liquids can form long-lived double layers, generating electric fields detectable by straightforward open circuit potential (OCP) measurements. In imidazolium-based ionic liquids an external negative voltage pulse leads to an exceedingly stable near-surface dipolar layer, whose field manifests as long-lived (∼1-100 h) discrete plateaus in OCP ... Read more >>

J Am Chem Soc (Journal of the American Chemical Society)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Toward an Intelligent Synthesis: Monitoring and Intervening in the Catalytic Growth of Carbon Nanotubes.

Zebin Liu, Jiangtao Wang, Ke Zhang, Xinyu Gao, Peng Liu, Qunqing Li, Lina Zhang, Shoushan Fan, Jing Kong, Kaili Jiang,

The bottom-up approach to directly synthesizing low-dimensional materials with outstanding performance has extended the material basis for the next generation integrated circuit industry. All the low-dimensional semiconductors, metals, dielectrics, and their heterojunctions are very promising bricks to build faster and more efficient chips because of their atomically smooth surface and ... Read more >>

J Am Chem Soc (Journal of the American Chemical Society)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Catalyst Design Principles Enabling Intermolecular Alkene-Diene [2+2] Cycloaddition and Depolymerization Reactions.

Megan Mohadjer Beromi, Jarod M Younker, Hongyu Zhong, Tyler P Pabst, Paul J Chirik,

Aryl-substituted pyridine(diimine) iron complexes promote the catalytic [2 + 2] cycloadditions of alkenes and dienes to form vinylcyclobutanes as well as the oligomerization of butadiene to generate divinyl(oligocyclobutane), a microstructure of poly(butadiene) that is chemically recyclable. A systematic study on a series of iron butadiene complexes as well as their ... Read more >>

J Am Chem Soc (Journal of the American Chemical Society)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Dynamic Surface Layer Coiled Coil Proteins Processing Analog-to-Digital Information.

Chiara Glionna, Vinod Kumar, Guillaume Le Saux, Bapan Pramanik, Nathaniel Wagner, Rivka Cohen-Luria, Gonen Ashkenasy, Nurit Ashkenasy,

Surface layer proteins perform multiple functions in prokaryotic cells, including cellular defense, cell-shape maintenance, and regulation of import and export of materials. However, mimicking the complex and dynamic behavior of such two-dimensional biochemical systems is challenging, and hence research has so far focused mainly on the design and manipulation of ... Read more >>

J Am Chem Soc (Journal of the American Chemical Society)
[2021, :]

Cited: 0 times

View full text PDF listing >>



All-Red-Light Photoswitching of Indirubin Controlled by Supramolecular Interactions.

Stefan Thumser, Laura Köttner, Nadine Hoffmann, Peter Mayer, Henry Dube,

Red-light responsiveness of photoswitches is a highly desired property for many important application areas such as biology or material sciences. The main approach to elicit this property uses strategic substitution of long-known photoswitch motives such as azobenzenes or diarylethenes. Only very few photoswitches possess inherent red-light absorption of their core ... Read more >>

J Am Chem Soc (Journal of the American Chemical Society)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Double-Walled [email protected] Multicomponent Senary Metal-Organic Polyhedral Framework and Its Isoreticular Evolution.

Zhiyong Lu, Liting Du, Ruyong Guo, Guangbao Zhang, Jingui Duan, Jianfeng Zhang, Lin Han, Junfeng Bai, Joseph T Hupp,

Metal-organic polyhedral frameworks are attractive in gas storage and separation due to large voids with windows that can serve as traps for guest molecules. Introducing multivariant/multicomponent functionalities in them are ways of improving performances for certain targets. The high compatibility of organic linkers can generate multivariant MOFs, but by far, ... Read more >>

J Am Chem Soc (Journal of the American Chemical Society)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Boron-Containing Organic Diradicaloids: Dynamically Modulating Singlet Diradical Character by Lewis Acid-Base Coordination.

Jiaxiang Guo, Yue Yang, Chuandong Dou, Yue Wang,

Organic diradicaloids have unique open-shell structures and properties and promising applications in organic electronics and spintronics. Incorporation of heteroatoms is an effective strategy to alter the electronic structures of organic diradicaloids. However, B-containing organic diradicaloids are very challenging due to their high reactivities, which are caused by not only diradical ... Read more >>

J Am Chem Soc (Journal of the American Chemical Society)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Predicting Mutational Effects on Receptor Binding of the Spike Protein of SARS-CoV-2 Variants.

Chen Bai, Junlin Wang, Geng Chen, Honghui Zhang, Ke An, Peiyi Xu, Yang Du, Richard D Ye, Arjun Saha, Aoxuan Zhang, Arieh Warshel,

The pandemic caused by SARS-CoV-2 has cost millions of lives and tremendous social/financial loss. The virus continues to evolve and mutate. In particular, the recently emerged "UK", "South Africa", and Delta variants show higher infectivity and spreading speed. Thus, the relationship between the mutations of certain amino acids and the ... Read more >>

J Am Chem Soc (Journal of the American Chemical Society)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Lithium-Conducting Self-Assembled Organic Nanotubes.

Michael J Strauss, Insu Hwang, Austin M Evans, Anusree Natraj, Xavier Aguilar-Enriquez, Ioannina Castano, Emily K Roesner, Jang Wook Choi, William R Dichtel,

Supramolecular polymers are compelling platforms for the design of stimuli-responsive materials with emergent functions. Here, we report the assembly of an amphiphilic nanotube for Li-ion conduction that exhibits high ionic conductivity, mechanical integrity, electrochemical stability, and solution processability. Imine condensation of a pyridine-containing diamine with a triethylene glycol functionalized isophthalaldehyde ... Read more >>

J Am Chem Soc (Journal of the American Chemical Society)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Mechanism-Based Design of Quinoline Potassium Acyltrifluoroborates for Rapid Amide-Forming Ligations at Physiological pH.

Matthias Tanriver, Yi-Chung Dzeng, Sara Da Ros, Erwin Lam, Jeffrey W Bode,

Potassium acyltrifluoroborates (KATs) undergo chemoselective amide-forming ligations with hydroxylamines. Under aqueous, acidic conditions these ligations can proceed rapidly, with rate constants of ∼20 M<sup>-1</sup> s<sup>-1</sup>. The requirement for lower pH to obtain the fastest rates, however, limits their use with certain biomolecules and precludes in vivo applications. By mechanistic investigations ... Read more >>

J Am Chem Soc (Journal of the American Chemical Society)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Palladium-Catalyzed Living/Controlled Vinyl Addition Polymerization of Cyclopropenes.

Zepeng Zhang, Yunpeng Gao, Shufeng Chen, Jianbo Wang,

Despite the various utilities of cyclopropenes (CPEs) in organic synthesis and ring-opening metathesis polymerization (ROMP), their vinyl addition polymerization has been sporadically explored, and the corresponding living/controlled polymerization remains a formidable challenge. The major obstacle is the intrinsic instability of the intermediate and the kinetic barrier for propagation. Herein a ... Read more >>

J Am Chem Soc (Journal of the American Chemical Society)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Protein-Protein Interactions Induce pH-Dependent and Zeaxanthin-Independent Photoprotection in the Plant Light-Harvesting Complex, LHCII.

Minjung Son, Raymundo Moya, Alberta Pinnola, Roberto Bassi, Gabriela S Schlau-Cohen,

Plants use energy from the sun yet also require protection against the generation of deleterious photoproducts from excess energy. Photoprotection in green plants, known as nonphotochemical quenching (NPQ), involves thermal dissipation of energy and is activated by a series of interrelated factors: a pH drop in the lumen, accumulation of ... Read more >>

J Am Chem Soc (Journal of the American Chemical Society)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Near-Unity Singlet Fission on a Quantum Dot Initiated by Resonant Energy Transfer.

Jie Zhang, Hayato Sakai, Katsuaki Suzuki, Taku Hasobe, Nikolai V Tkachenko, I-Ya Chang, Kim Hyeon-Deuk, Hironori Kaji, Toshiharu Teranishi, Masanori Sakamoto,

The conversion of a high-energy photon into two excitons using singlet fission (SF) has stimulated a variety of studies in fields from fundamental physics to device applications. However, efficient SF has only been achieved in limited systems, such as solid crystals and covalent dimers. Here, we established a novel system ... Read more >>

J Am Chem Soc (Journal of the American Chemical Society)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Expanding the Structural Diversity and Functional Scope of Diphenylalanine-Based Peptide Architectures by Hierarchical Coassembly.

Wei Ji, Yiming Tang, Pandeeswar Makam, Yifei Yao, Ranran Jiao, Kaiyong Cai, Guanghong Wei, Ehud Gazit,

Modulation of the structural diversity of diphenylalanine-based assemblies by molecular modification and solvent alteration has been extensively explored for bio- and nanotechnology. However, regulation of the structural transition of assemblies based on this minimal building block into tunable supramolecular nanostructures and further construction of smart supramolecular materials with multiple responsiveness ... Read more >>

J Am Chem Soc (Journal of the American Chemical Society)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Dehydration of Electrochemically Protonated Oxide: SrCoO2 with Square Spin Tubes.

Hao-Bo Li, Shunsuke Kobayashi, Chengchao Zhong, Morito Namba, Yu Cao, Daichi Kato, Yoshinori Kotani, Qianmei Lin, Maokun Wu, Wei-Hua Wang, Masaki Kobayashi, Koji Fujita, Cédric Tassel, Takahito Terashima, Akihide Kuwabara, Yoji Kobayashi, Hiroshi Takatsu, Hiroshi Kageyama,

Controlling oxygen deficiencies is essential for the development of novel chemical and physical properties such as high-<i>T</i><sub>c</sub> superconductivity and low-dimensional magnetic phenomena. Among reduction methods, topochemical reactions using metal hydrides (e.g., CaH<sub>2</sub>) are known as the most powerful method to obtain highly reduced oxides including Nd<sub>0.8</sub>Sr<sub>0.2</sub>NiO<sub>2</sub> superconductor, though there are ... Read more >>

J Am Chem Soc (Journal of the American Chemical Society)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Ubiquitous Nature of Rate Retardation in Reversible Addition-Fragmentation Chain Transfer Polymerization.

Kate G E Bradford, Leilah M Petit, Richard Whitfield, Athina Anastasaki, Christopher Barner-Kowollik, Dominik Konkolewicz,

Reversible addition-fragmentation chain transfer (RAFT) polymerization is one of the most powerful reversible deactivation radical polymerization (RDRP) processes. Rate retardation is prevalent in RAFT and occurs when polymerization rates deviate from ideal conventional radical polymerization kinetics. Herein, we explore beyond what was initially thought to be the culprit of rate ... Read more >>

J Am Chem Soc (Journal of the American Chemical Society)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Higher Order Protein Catenation Leads to an Artificial Antibody with Enhanced Affinity and In Vivo Stability.

Wen-Hao Wu, Xilin Bai, Yu Shao, Chao Yang, Jingjing Wei, Wei Wei, Wen-Bin Zhang,

The chemical topology is a unique dimension for protein engineering, yet the topological diversity and architectural complexity of proteins remain largely untapped. Herein, we report the biosynthesis of complex topological proteins using a rationally engineered, cross-entwining peptide heterodimer motif derived from p53dim (an entangled homodimeric mutant of the tetramerization domain ... Read more >>

J Am Chem Soc (Journal of the American Chemical Society)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Mechanism-Based Inactivation of Mycobacterium tuberculosis Isocitrate Lyase 1 by (2R,3S)-2-Hydroxy-3-(nitromethyl)succinic acid.

Drake M Mellott, Dan Torres, Inna V Krieger, Scott A Cameron, Zahra Moghadamchargari, Arthur Laganowsky, James C Sacchettini, Thomas D Meek, Lawrence D Harris,

The isocitrate lyase paralogs of Mycobacterium tuberculosis (ICL1 and 2) are essential for mycobacterial persistence and constitute targets for the development of antituberculosis agents. We report that (2R,3S)-2-hydroxy-3-(nitromethyl)succinic acid (5-NIC) undergoes apparent retro-aldol cleavage as catalyzed by ICL1 to produce glyoxylate and 3-nitropropionic acid (3-NP), the latter of which is ... Read more >>

J Am Chem Soc (Journal of the American Chemical Society)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Voltage-Driven Molecular Catalysis of Electrochemical Reactions.

Koushik Barman, Xiang Wang, Rui Jia, Gaukhar Askarova, Guoxiang Hu, Michael V Mirkin,

Heterogeneous electrocatalysis and molecular redox catalysis have developed over several decades as two distinct ways to facilitate charge-transfer processes essential for energy conversion and storage. Whereas electrocatalytic reactions are driven by the applied voltage, molecular catalytic processes are driven by the difference between standard potentials of the catalyst and the ... Read more >>

J Am Chem Soc (Journal of the American Chemical Society)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Supramolecular Organization of Polymer Prodrug Nanoparticles Revealed by Coarse-Grained Simulations.

Ping Gao, Julien Nicolas, Tâp Ha-Duong,

Drug-polymer conjugates that can self-assemble into nanoparticles are promising drug delivery systems that improve the drug bioavailability and allow their controlled release. However, despite the possibility of reaching high drug loadings, the efficiency of the drug release, mediated by cleavage of the drug-polymer linker, is a key parameter to obtain ... Read more >>

J Am Chem Soc (Journal of the American Chemical Society)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Advertisement


Disclaimer

0.9848 s