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High-school students and self-injurious thoughts and behaviours: clues of emotion dysregulation.

Caterina Zanus, Sara Battistutta, Renata Aliverti, Lorenzo Monasta, Marcella Montico, Luca Ronfani, Marco Carrozzi,

<h4>Background</h4>Suicide attempts and self-harm in adolescence are a major public health concern: they are among the main causes of disability-adjusted life-years worldwide, with severe long-term health consequences in terms of mental illness and psychiatric hospitalisation and a significantly increased risk of suicide. Several studies recently focused on the hypothesis that ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):14]

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Aromatic L-amino Acid Decarboxylase (AADC) deficiency: results from an Italian modified Delphi consensus.

Carlo Fusco, Vincenzo Leuzzi, Pasquale Striano, Roberta Battini, Alberto Burlina, , Carlotta Spagnoli,

<h4>Background</h4>Aromatic L-amino acid decarboxylase (AADC) deficiency is a rare and underdiagnosed neurometabolic disorder resulting in a complex neurological and non-neurological phenotype, posing diagnostic challenges resulting in diagnostic delay. Due to the low number of patients, gathering high-quality scientific evidence on diagnosis and treatment is difficult. Additionally, based on the estimated ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):13]

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The risks of physicians' conformism: reflections from the opioid overflow.

Luisa Cortellazzo Wiel, Giorgio Cozzi, Egidio Barbi,

Opioid-related mortality in adolescents is spreading in the US, with prescription opioids playing a crucial role in the development of addiction. We traced back to the process leading to the so called "opioid overflow", trying to identify any modifiable attitude.Since the late 1990s, pain was labelled as the "fifth vital ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):10]

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Utility of a pediatric observation unit for the management of children admitted to the emergency department.

Antonio Gatto, Serena Rivetti, Lavinia Capossela, Davide Pata, Marcello Covino, Antonio Chiaretti,

<h4>Background</h4>Observation Units (OU), as part of emergency department (ED), are areas reserved for short-term treatment or observation of patients with selected diagnoses to determine the need for hospitalization or home referral.<h4>Methods</h4>In this retrospective cohort study, we analyzed similarities and differences of children admitted to the pediatric ED of the Fondazione ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):11]

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Comprehensive and safe school strategy during COVID-19 pandemic.

Susanna Esposito, Nicola Cotugno, Nicola Principi,

<h4>Background</h4>Although several studies have tried to evaluate the real efficacy of school closure for pandemic control over time, no definitive answer to this question has been given. Moreover, it has not been clarified whether children or teenagers could be considered a problem for SARS-CoV-2 diffusion or, on the contrary, whether ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):6]

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Morbidity associated with patent ductus arteriosus in preterm newborns: a retrospective case-control study.

Gianluca Terrin, Maria Di Chiara, Giovanni Boscarino, Valentina Metrangolo, Francesca Faccioli, Elisa Onestà, Antonella Giancotti, Violante Di Donato, Viviana Cardilli, Mario De Curtis,

<h4>Introduction</h4>Association between persistency of a patent ductus arteriosus (PDA) and morbidity in preterm newborns is still controversial. We aimed to investigate the relation between PDA and morbidity in a large retrospective study.<h4>Methods</h4>A case-control study including neonates consecutively admitted to the Neonatal Intensive Care Unit (NICU), with gestational age (GA) < 32 weeks or ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):9]

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COVID-19 lockdown beneficial effects on lung function in a cohort of cystic fibrosis patients.

Alessia Giuseppina Servidio, Giulia Capata, Laura Levantino, Guglielmo Riccio, Sarah Contorno, Egidio Barbi, Massimo Maschio,

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):12]

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The child with medical complexity.

Manuela Gallo, Rino Agostiniani, Roberta Pintus, Vassilios Fanos,

Children with medical complexity represent a big challenge for the physicians, their families and the society as well. Although there is no clear definition of this type of patients, they are affected by a chronic, often very severe condition for their whole life. They also represent a huge cost for ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):1]

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Risk factors for severity of thrombocytopenia in full term infants: a single center study.

Amira M Saber, Shereen P Aziz, Al Zahraa E Almasry, Ramadan A Mahmoud,

<h4>Background</h4>Neonatal thrombocytopenia (NT) (platelet count < 150 × 10<sup>9</sup>/L) is a common finding in the neonatal intensive care unit (NICU). The main aim of this study was to assess the prevalence, risk factors, and outcomes of severe NT in full term (FT) infants.<h4>Methods</h4>During the study period, all FT infants who met the inclusion ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):7]

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PTSD in parents of children with severe diseases: a systematic review to face Covid-19 impact.

Martina Corsi, Alessandro Orsini, Virginia Pedrinelli, Andrea Santangelo, Carlo Antonio Bertelloni, Niccolò Carli, Rodolfo Buselli, Diego Peroni, Pasquale Striano, Liliana Dell'Osso, Claudia Carmassi,

<h4>Context</h4>The literature agrees on the impact of post-traumatic stress symptoms in parents of seriously ill children but there is less clarity about the real extent and gender differences of this psychopathological risk. The recent Covid-19 outbreak highlighted new burdens for researchers on Post Traumatic Stress Disorder (PTSD) and clear evidence-based ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):8]

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Clinical warning of hemophagocytic syndrome caused by Epstein-Barr virus.

Jinjin Shi, Chu Chu, Min Yu, Dandan Zhang, Yuqin Li, Yujie Fan, Yixue Yu, Yali Luo, Weifang Zhou,

<h4>Objectives</h4>This study aimed to compare the clinical features and laboratory tests of infectious mononucleosis (IM) and hemophagocytic syndrome (HLH) caused by Epstein-Barr virus (EBV) in 1-3-year-old children and to explore the risk factor of HLH caused by EBV (EBV-HLH).<h4>Methods</h4>The clinical data of 92 children with EBV infection admitted in our ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):3]

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Molecular screening of PROKR2 gene in girls with idiopathic central precocious puberty.

Francesca Aiello, Grazia Cirillo, Alessandra Cassio, Raffaella Di Mase, Gianluca Tornese, Giuseppina R Umano, Emanuele Miraglia Del Giudice, Anna Grandone,

<h4>Background</h4>Prokineticin receptor 2 (PROKR2) loss of function mutations have been described as cause of hypogonadotropic hypogonadism. In 2017, a first case of central precocious puberty (CPP) caused by PROKR2 heterozygous gain of function mutation was described in a 3.5 years-old girl. No other cases have been reported yet. This study performs ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):5]

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An estimation of the number of children requiring pediatric palliative care in Italy.

Franca Benini, Mariadonata Bellentani, Laura Reali, Pierina Lazzarin, Lucia De Zen, Federico Pellegatta, Pierangelo Lora Aprile, Gianlorenzo Scaccabarozzi,

<h4>Background</h4>Pediatric palliative care (PPC) addresses the physical and psychological needs of children suffering from life-limiting diseases. To define prevention and educational plans and to properly allocate resources, a precise estimation of the PPC burden is required.<h4>Objectives</h4>To estimate the current number of children requiring PPC in Italy, useful to assist policy-makers ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):4]

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High-school students and self-injurious thoughts and behaviours: clues of emotion dysregulation

Caterina Zanus, Sara Battistutta, Renata Aliverti, Lorenzo Monasta, Marcella Montico, Luca Ronfani, Marco Carrozzi,

<h4>Background</h4> Suicide attempts and self-harm in adolescence are a major public health concern: they are among the main causes of disability-adjusted life-years worldwide, with severe long-term health consequences in terms of mental illness and psychiatric hospitalisation and a significantly increased risk of suicide. Several studies recently focused on the hypothesis ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):]

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Cystic fibrosis in Tuscany: evolution of newborn screening strategies over time to the present.

Matteo Botti, Vito Terlizzi, Michela Francalanci, Daniela Dolce, Maria Chiara Cavicchi, Anna Silvia Neri, Valeria Galici, Gianfranco Mergni, Lucia Zavataro, Claudia Centrone, Filippo Festini, Giovanni Taccetti,

<h4>Background</h4>Cystic fibrosis (CF) is a life-threatening disease affecting about 1:3000 newborns in Caucasian populations. The introduction of newborn screening for cystic fibrosis (CF NBS) has improved the clinical outcomes of individuals with CF through early diagnosis and early treatment. NBS strategies have been implemented over time. CF NBS was introduced ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):2]

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SARS-CoV-2 pandemia in Lombardy: the impact on family Paediatricians.

Rinaldo Missaglia, Michael Belingheri, Laura Antolini, Monica De' Angelis, Luca Brivio, Michele Augusto Riva, Simonetta Genovesi,

As health care workers (HCWs) who care for children, who usually demonstrate milder symptoms than adults, family paediatricians have an increased risk of exposure to coronavirus. In April 2020, the Sindacato Medici Pediatri di Famiglia (SIMPeF), provided its members with rapid tests to detect antibodies against SARS-CoV-2; 1240 individuals, including ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2020, 46(1):184]

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Proceedings of the 33rd Congress of the Italian Society of Neonatology, Lombardy Section, 31 January - 1 February 2020 : Bergamo, Italy. 31 January-01 February 2020.

Ital J Pediatr (Italian journal of pediatrics)
[2020, 46(Suppl 2):183]

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Spectrum of thrombotic complications and their outcomes in Chinese children with primary nephrotic syndrome.

Yan-Li Lv, Na Guan, Jie Ding, Yong Yao, Hui-Jie Xiao, Xu-Hui Zhong, Fang Wang, Xiao-Yu Liu, Hong-Wen Zhang, Bai-Ge Su, Ke Xu,

<h4>Background</h4>Thromboembolism is a life-threatening, limb-threatening or organ-threatening complication that occurs in patients with primary nephrotic syndrome (NS). There are few studies on the spectrum, complications and outcomes of thrombosis in children with NS. This study aimed to determine the spectrum of thrombosis and its relationship with the nephrotic state, treatment ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2020, 46(1):182]

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A neonatal cluster of novel coronavirus disease 2019: clinical management and considerations.

Nicole Olivini, Francesca Ippolita Calò Carducci, Veronica Santilli, Maria Antonietta De Ioris, Alessia Scarselli, Dario Alario, Caterina Geremia, Mary Haywood Lombardi, Caterina Marabotto, Rosanna Mariani, Raffaele Edo Papa, Emanuela Peschiaroli, Raffaella Scrocca, Serena Sinibaldi, Andrea Smarrazzo, Pietro Stella, Stefania Bernardi, Sara Chiurchiù, Paola Pansa, Lorenza Romani, Carletti Michaela, Carlo Concato, Domenico Umberto De Rose, Gugliemo Salvatori, Paolo Rossi, Alberto Villani, Andrea Dotta, Patrizia D'Argenio, Andrea Campana,

<h4>Background</h4>Lately, one of the major clinical and public health issues has been represented by Coronavirus disease of 2019 (COVID-19) during pregnancy and the risk of transmission of the infection from mother to child. Debate on perinatal management and postnatal care is still ongoing, principally questioning the option of the joint ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2020, 46(1):180]

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Criteria for referral of pediatric SARS-CoV-2 infection: a real-life experience in the pandemic era.

Carlotta Montagnani, Elisabetta Venturini, Manuela L'Erario, Chiara Tersigni, Barbara Bortone, Leila Bianchi, Francesca Menegazzo, Giuseppe Indolfi, Elena Chiappini, Luisa Galli,

A practical guidance on the management of children with COVID-19 to insure homogeneous criteria for referral to a higher-level facility, according to the disease severity, is pivotal in the pandemic era. A panel of experts in pediatric infectious diseases and intensive care at the tertiary-care Meyer Children's University Hospital, Florence, ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2020, 46(1):181]

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Children with special health care needs attending emergency department in Italy: analysis of 3479 cases.

Paola Cianci, Valeria D'Apolito, Alex Moretti, Massimo Barbagallo, Sabrina Paci, Maria Teresa Carbone, Riccardo Lubrano, Antonio Urbino, Carlo Dionisi Vici, Luigi Memo, Giuseppe Zampino, Giancarlo La Marca, Alberto Villani, Giovanni Corsello, Angelo Selicorni, , , ,

<h4>Background</h4>Although children with special health care needs (CSHCN) represent a minority of the population, they go through more hospitalizations, more admissions to the Emergency Department (ED), and receive a major number of medical prescriptions, in comparison to general pediatric population. Objectives of the study were to determine the reasons for ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2020, 46(1):173]

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Abdominal pain as first manifestation of lyme neuroborreliosis in children, case report and review of literature.

Salvatore Savasta, Ivan Fiorito, Thomas Foiadelli, Anna Pichiecchio, Patrizia Cambieri, Bianca Mariani, Piero Marone, Gianluigi Marseglia,

<h4>Background</h4>Lyme neuroborreliosis can cause a variety of neurological manifestations. European children usually present facial nerve palsy, other cranial nerve palsies and aseptic meningitis.<h4>Case presentation</h4>We hereby report a case of Lyme neuroborreliosis in a 9-year-old boy with abdominal pain as first symptom and subsequent onset of attention deficit and ataxia. Diagnosis ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2020, 46(1):172]

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Pooled prevalence and determinants of skilled birth attendant delivery in East Africa countries: a multilevel analysis of Demographic and Health Surveys.

Zemenu Tadesse Tessema, Getayeneh Antehunegn Tesema,

<h4>Introduction</h4>Skilled health professional assisted delivery is an effective strategy to reduce maternal and newborn mortality. Skilled assistant delivery can prevent about 16-33% of maternal and newborn mortality. Despite the commitments of the government to assure home free delivery, majority of the births in Sub-Saharan Africa are attended by traditional birth ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2020, 46(1):177]

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Determinants of postnatal care utilization in sub-Saharan Africa: a meta and multilevel analysis of data from 36 sub-Saharan countries.

Zemenu Tadesse Tessema, Lake Yazachew, Getayeneh Antehunegn Tesema, Achamyeleh Birhanu Teshale,

<h4>Introduction</h4>Globally, over 65% of maternal deaths occur during the first 42 days of postpartum while the same proportion of neonatal deaths occur during the first 7 days of life. In sab- Saharan Africa, 4.7 million mothers, newborns, and children die on annual basis. As to our knowledge, there is no study ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2020, 46(1):175]

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Iatrogenic severe hyperglycemia due to parenteral administration of glucose in children - a case series.

Nora Bruns, Anja Große Lordemann, Tobias Rasche, Jochen Meyburg, Marcus Krüger, Christian Wieg, Alexander Gratopp, Marc Hoppenz, Friedhelm Heitmann, Thomas Hoppen, Günther Löffler, Ursula Felderhoff-Müser, Christian Dohna-Schwake,

<h4>Background</h4>Iatrogenic severe hyperglycemia (ISH) caused by glucose-containing i.v. solution is a potentially fatal treatment error. The objective of this study was to investigate the causes, circumstances, course of disease, and complications of ISH > 300 mg/dl (16.7 mmol/l) in neonates and children.<h4>Methods</h4>We emailed a survey to 105 neonatal and pediatric intensive care units in ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2020, 46(1):179]

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