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Journal Ital J Pediatr

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The lockdown effects on a pediatric obese population in the COVID-19 era.

M Valenzise, F D'Amico, U Cucinotta, C Lugarà, G Zirilli, A Zema, M Wasniewska, G B Pajno,

The social consequences of COVID-19 pandemic are universally known. In particular, the pediatric population is dealing with a radical lifestyle change. For some risk categories, such as overweight or obese children, the impact of home confinement has been greater than for others. The increased sedentary life, the wrong diet and ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):209]

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Under-nutrition and associated factors among children on ART in Southern Ethiopia: a facility-based cross-sectional study.

Chalie Marew Tiruneh, Belete Gelaw Walle, Tigabu Desie Emiru, Nigusie Selomon Tibebu, Moges Wubneh Abate, Adane Birhanu Nigat, Amsalu Belete, Eyasu Alem, Tadele Lankrew, Kirubel Eshetu,

<h4>Background</h4>Malnutrition is very common in HIV-infected individuals. Even though data from different settings are necessary to tackle it, pieces of evidence are limited especially in the case of the nutritional status of HIV-infected children. Hence, this study aims to assess the nutritional status and associated factors among children on antiretroviral ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):205]

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Idiopathic neonatal hemoperitoneum presented as scrotal hematoma: it's a diagnostic challenge?

Salatto Alessia, Indrio Flavia, Campanella Vittoria, Maggipinto Cosetta, Cocomazzi Raffaella, Canale Francesco, Nobili Maria, Maffei Gianfranco, Bartoli Fabio,

<h4>Background</h4>Idiopathic hemoperitoneum in the newborn is an entity very rarely encountered in clinical practice.<h4>Case presentation</h4>A case of scrotal hemorrhage (SH) associated with intrabdominal hemorrhaging and acute anemia is presented. Indications for early surgery included a massive scrotal hematoma, rapid onset of severe anemia, and unknown etiology.<h4>Conclusion</h4>Clinical and diagnostic approaches in ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):207]

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Management of asymptomatic hypoglycemia with 40% oral dextrose gel in near term at-risk infants to reduce intensive care need and promote breastfeeding.

Fabio Meneghin, Martina Manzalini, Miriam Acunzo, Irene Daniele, Petrina Bastrenta, Francesca Castoldi, Francesco Cavigioli, Gian Vincenzo Zuccotti, Gianluca Lista,

<h4>Background</h4>Neonatal hypoglycemia is a common disorder especially in at-risk infants and it can be associated with poor long-term neurological outcomes. Several therapeutic interventions are suggested, from the implementation of breastfeeding to the glucose intravenous administration. Oral dextrose gel massaged into the infant's inner cheek is a recent treatment option of ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):201]

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Breastfeeding technique and associated factors among lactating mothers visiting Gondar town health facilities, Northwest Ethiopia: observational method.

Boko Loka Safayi, Nega Tezera Assimamaw, Destaye Guadie Kassie,

<h4>Background</h4>The breastfeeding technique is explained positioning, attachment, and suckling during breastfeeding. Ineffective breast feeding technique is one of the factors leading to premature discontinuation of breastfeeding and malnutrition. There is a limited study on the assessments of BFT and associated factors among lactating mothers in the study area. Therefore, the ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):206]

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Distance learning, technological devices, lifestyle and behavior of children and their family during the COVID-19 lockdown in Lombardy: a survey.

Marina Picca, Paola Manzoni, Gregorio Paolo Milani, Susanna Mantovani, Claudio Cravidi, Danila Mariani, Angela Mezzopane, Roberto Marinello, Chiara Bove, Paolo Ferri, Marina Macchi, Carlo Agostoni,

<h4>Background</h4>The COVID-19 pandemic and the subsequent national lockdowns, school closures and distance learning may have had both negative and positive effects on physical and mental health of children.<h4>Methods</h4>A cross-sectional study was conducted on a large group of children between 1 and 10 years old in Lombardy, Italy (n = 3392). Their parents filled in ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):203]

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Hemoglobin life-threatening value (1.9 g/dl) in good general condition: a pediatric case-report.

Emilia Parodi, Lorenzo Riboldi, Ugo Ramenghi,

<h4>Background</h4>We report a pediatric patient presenting in good general condition despite a hemoglobin value of 1,9 g/dL, which is normally regarded as life-threatening.<h4>Case presentation</h4>An African 5 years-old girl presented to our Emergency Department (ED) for worsening asthenia, within a clinical picture of good general condition. The hemoglobin value at admission was 1,9 g/dL. ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):200]

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Hyperkinetic stereotyped movements in a boy with biallelic CNTNAP2 variants.

Marcello Scala, Midas Anijs, Roberta Battini, Francesca Madia, Valeria Capra, Paolo Scudieri, Alberto Verrotti, Federico Zara, Carlo Minetti, Sonja C Vernes, Pasquale Striano,

<h4>Background</h4>Heterozygous variants in CNTNAP2 have been implicated in a wide range of neurological phenotypes, including intellectual disability (ID), epilepsy, autistic spectrum disorder (ASD), and impaired language. However, heterozygous variants can also be found in unaffected individuals. Biallelic CNTNAP2 variants are rarer and cause a well-defined genetic syndrome known as CASPR2 ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):208]

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Congenital hemophilia A with low activity of factor XII: a case report and literature review.

Baoyu Lei, Chuang Liang, Haiyan Feng,

<h4>Background</h4>Congenital hemophilia A is a recessive inherited hemorrhagic disorder. According to the activity of functional coagulation factors, the severity of hemophilia A is divided into three levels: mild, moderate and severe. The first bleeding episode in severe and moderate congenital hemophilia A occurs mostly in early childhood and mainly involves ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):204]

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Epidemiology and prevention of respiratory syncytial virus infections in children in Italy.

Chiara Azzari, Eugenio Baraldi, Paolo Bonanni, Elena Bozzola, Alessandra Coscia, Marcello Lanari, Paolo Manzoni, Teresa Mazzone, Fabrizio Sandri, Giovanni Checcucci Lisi, Salvatore Parisi, Giorgio Piacentini, Fabio Mosca,

Respiratory syncytial virus (RSV) is the leading global cause of respiratory infections in infants and the second most frequent cause of death during the first year of life. This highly contagious seasonal virus is responsible for approximately 3 million hospitalizations and 120,000 deaths annually among children under the age of ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):198]

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Hypertrophic cardiomyopathy in infant newborns of diabetic mother: a heterogeneous condition, the importance of anamnesis, physical examination and follow-up.

Alessia Claudia Codazzi, Rosario Ippolito, Cecilia Novara, Enrico Tondina, Rosa Maria Cerbo, Chryssoula Tzialla,

<h4>Background</h4>Hypertrophic cardiomyopathy (HCM) in neonates is a rare and heterogeneous disorder. HCM accounts for 25 to 40% of all pediatric cardiomyopathy cases and the highest incidence in pediatric population is reported in children < 1 year.<h4>Case presentation</h4>we report two clinical cases of neonates, born to mothers respectively with a pre-pregnancy insulin-dependent diabetic ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):197]

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Treatment of children with COVID-19: update of the Italian Society of Pediatric Infectious Diseases position paper.

Elisabetta Venturini, Carlotta Montagnani, Silvia Garazzino, Daniele Donà, Luca Pierantoni, Andrea Lo Vecchio, Andrzej Krzysztofiak, Giangiacomo Nicolini, Sonia Bianchini, Luisa Galli, Alberto Villani, Guido Castelli Gattinara, ,

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):199]

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Long term treatment with omalizumab in adolescent with refractory solar urticaria.

Mauro Iannelli, Stefano Passanisi, Giuseppe Crisafulli, Stefania Arasi, Lucia Caminiti, Giuseppina Zirilli, Giovanni B Pajno,

<h4>Background</h4>Solar urticaria represents an uncomfortable form of chronic inducible urticaria. First and second-line treatments are ineffective in some patients, leading to an impairment in their quality of life. Omalizumab represents a safe therapeutic option in case of refractory solar urticaria.<h4>Case presentation</h4>We update a case of a 21-year-old Caucasian girl affected ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):195]

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A new scoring system and clinical algorithm for the management of suspected foreign body aspiration in children: a retrospective cohort study.

Nader A Fasseeh, Osama A Elagamy, Alaa H Gaafar, Heba M Reyad, Mohamed S Abougabal, Doaa A Heiba, Ahmad Kantar,

<h4>Background</h4>Cases of foreign body aspiration in children may be encountered in emergency departments. A suggestive history is important in diagnosing aspirated foreign body owing to the difficulty in making a diagnosis on the basis of an abnormal physical examination or chest radiography alone. The aim of this study was to ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):194]

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Novel missense mutation of the TP63 gene in a newborn with Hay-Wells/Ankyloblepharon-Ectodermal defects-Cleft lip/palate (AEC) syndrome: clinical report and follow-up.

Gregorio Serra, Vincenzo Antona, Mario Giuffré, Federica Li Pomi, Lucia Lo Scalzo, Ettore Piro, Ingrid Anne Mandy Schierz, Giovanni Corsello,

<h4>Introduction</h4>Ankyloblepharon-ectodermal defects-cleft lip/palate (AEC) syndrome, also known as Hay-Wells syndrome, is a rare genetic syndrome with ectodermal dysplasia. About 100 patients have been reported to date. It is associated to a heterozygous mutation of the tumor protein p63 (TP63) gene, located on chromosome 3q28. Typical clinical manifestations include: filiform ankyloblepharon ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):196]

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Reasons for SARS-CoV-2 infection in children and their role in the transmission of infection according to age: a case-control study.

Mauro Calvani, Giulia Cantiello, Maria Cavani, Eleonora Lacorte, Bruno Mariani, Valentina Panetta, Pasquale Parisi, Gabriella Parisi, Federica Roccabella, Paola Silvestri, Nicola Vanacore,

<h4>Background</h4>The locations where children get exposed to SARS-CoV-2 infection and their contribution in spreading the infection are still not fully understood. Aim of the article is to verify the most frequent reasons for SARS-CoV-2 infection in children and their role in the secondary transmission of the infection.<h4>Methods</h4>A case-control study was ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):193]

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Correction to: Novel mutation in carnitine palmitoyltransferase 1A detected through newborn screening for a presymptomatic case in China: a case report.

Yi Gan, Fei Yu, Haining Fang,

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):192]

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Are we sure that the neurological impact of COVID 19 in childhood has not been underestimated?

Nicola Principi, Susanna Esposito,

<h4>Background</h4>Presently, it is known that, even if less frequently than in adults, children can develop a severe new coronavirus disease 2019 (COVID-19). Children with the SARS-CoV-2 infection can have neurological signs and symptoms of disease more frequently than previously thought, revealing the involvement of the central nervous system, the peripheral ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):191]

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15q26 deletion in a patient with congenital heart defect, growth restriction and intellectual disability: case report and literature review.

Yahya Benbouchta, Nicole De Leeuw, Saadia Amasdl, Aziza Sbiti, Dominique Smeets, Khalid Sadki, Abdelaziz Sefiani,

<h4>Background</h4>15q26 deletion is a relatively rare chromosomal disorder, and it is described only in few cases. Patients with this aberration show many signs and symptoms, particularly pre- and postnatal growth restriction, developmental delay, microcephaly, intellectual disability and various congenital malformations.<h4>Case presentation</h4>We report on a girl, 4 years old, of consanguineous ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):188]

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In-hospital and web-based intervention to counteract vaccine hesitancy in very preterm infants' families: a NICU experience.

Antonio Di Mauro, Federica Di Mauro, Chiara Greco, Orazio Valerio Giannico, Francesca Maria Grosso, Maria Elisabetta Baldassarre, Manuela Capozza, Federico Schettini, Pasquale Stefanizzi, Nicola Laforgia,

<h4>Background</h4>Vaccine hesitancy is a global problem, carrying significant health risks for extremely vulnerable population as that of preterm infants. Social media are emerging as significant tools for public health promotion. Our aim was to evaluate both the coverage and the timeliness of routine immunizations in a cohort of preterm infants ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):190]

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Correction to: Incidental finding of APC deletion in a child: double trouble or double chance? - a case report.

Erica Rosina, Berardo Rinaldi, Rosamaria Silipigni, Luca Bergamaschi, Giovanna Gattuso, Stefano Signoroni, Silvana Guerneri, Alessandra Carnevali, Paola Giovanna Marchisio, Donatella Milani,

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):185]

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Incidence and predictors of mortality among neonates referred to comprehensive and specialized hospitals in Amhara regional state, North Ethiopia: a prospective follow-up study.

Alex Yeshaneh, Bizuayehu Tadele, Bogale Dessalew, Mulunesh Alemayehu, Awraris Wolde, Addisu Adane, Solomon Shitu, Haimanot Abebe, Daniel Adane,

<h4>Background</h4>Neonatal mortality is a major global public health problem. Ethiopia is among seven countries that comprise 50 % of global neonatal mortality. Evidence on neonatal mortality in referred neonates is essential for intervention however, there is no enough information in the study area. Neonates who required referral frequently became unstable ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):186]

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High levels of unbound bilirubin are associated with acute bilirubin encephalopathy in post-exchange transfusion neonates.

Yiyi Ding, Shuo Wang, Rui Guo, Aizhen Zhang, Yufang Zhu,

<h4>Background</h4>Although it is known that unbound bilirubin can enter the brain, there is little evidence of its association with the development of acute bilirubin encephalopathy. Here, we investigated this potential relationship in neonates who had undergone exchange transfusion.<h4>Methods</h4>Data from 46 newborns who underwent exchange transfusion between 2016 and 1-1 to ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):187]

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Analysis of risk and prognostic factors in a population of pediatric patients hospitalized for acute malnutrition at the Chiulo hospital, Angola.

Federica Maria Tripoli, Salvatore Accomando, Simona La Placa, Andrea Pietravalle, Giovanni Putoto, Giovanni Corsello, Mario Giuffrè,

<h4>Background</h4>Malnutrition is a multifactorial pathology in which genetic, epigenetic, cultural, environmental, socio-economic factors interact with each other. The impact that this disease has on the health of children worldwide is dramatic. Severe acute malnutrition in particular is a disease affecting nearly 20 million preschool children worldwide, most of them in ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):184]

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Balloon dilation and rapid maxillary expansion: a novel combination treatment for congenital nasal pyriform aperture stenosis in an infant.

Emanuela Sitzia, Sara Santarsiero, Filippo Maria Tucci, Giovanni De Vincentiis, Angela Galeotti, Paola Festa,

<h4>Background</h4>Congenital nasal pyriform aperture stenosis (CNPAS) is a rare condition that may occur alone or as part of a multi-formative syndrome. Management remains difficult. There is no specific treatment protocol. Traditional surgery would be anachronistic; a non-invasive or minimally invasive therapeutic option is required. However, the rarity of the disease ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2021, 47(1):189]

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