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Journal Int. J. Radiat. Biol.

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Effects of gamma-irradiation on antibiotic resistance and diagnostic molecular markers of methicillin-resistant Staphylococcus aureus in Egyptian cancer patients.

Mona M K Shehata, Samah Mohamed Radwan, Sahar A M Ali,

Purpose: This in-vitro study aimed to assess in 120 [40 community-acquired (CA-MRSA) & 80 hospital-acquired (HA-MRSA)] isolates from cancer patients whether the transmissible staphylococcal cassette chromosome mec (SCCmec) typing, and the Panton-Valentine leukocidin (PVL) virulence genes detection could be employed as tools for molecular diagnostic purposes to distinguish both methicillin-resistant ... Read more >>

Int. J. Radiat. Biol. (International journal of radiation biology)
[2019, 95(12):1728-1743]

Cited: 0 times

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Effect of long-term occupational exposure to extremely low-frequency electromagnetic fields on proinflammatory cytokine and hematological parameters.

Majid Bagheri Hosseinabadi, Narges Khanjani, Seyed Ehsan Samaei, Fereshteh Nazarkhani,

Purpose: The present study aimed to investigate the effect of extremely low-frequency electromagnetic fields (ELF-EMFs) on proinflammatory cytokines and hematological parameters, among the employees of a power plant, which are one of the most important occupational groups exposed to ELF-EMFs extensively.Materials and methods: The studied population included 112 employees of ... Read more >>

Int. J. Radiat. Biol. (International journal of radiation biology)
[2019, 95(11):1573-1580]

Cited: 2 times

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LET dependence on killing effect and mutagenicity in the model filamentous fungus Neurospora crassa.

Liqiu Ma, Yusuke Kazama, Tomonari Hirano, Ryouhei Morita, Shuuitsu Tanaka, Tomoko Abe, Shin Hatakeyama,

PURPOSE:To assess the unique biological effects of different forms of ionizing radiation causing DNA double-strand breaks (DSBs), we compared the killing effect, mutagenesis frequency, and mutation type spectrum using the model filamentous fungus Neurospora. MATERIALS AND METHODS:Asexual spores of wild-type Neurospora and two DSB repair-deficient strains [one homologous recombination- and ... Read more >>

Int. J. Radiat. Biol. (International journal of radiation biology)
[2018, 94(12):1125-1133]

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Proactive strategy for long-term biological research aimed at low-dose radiation risk in Korea.

Ki Moon Seong, TaeWoo Kwon, Jina Park, BuHyun Youn, Hyuk-Jin Cha, Yonghwan Kim, Changjong Moon, Seung-Sook Lee, Young Woo Jin,

PURPOSE:Since the 2011 Fukushima nuclear power plant accident, Korean radiation experts have agreed that reliable data on health risks of low-dose radiation (LDR) are needed to ease the anxiety of lay people. The intent of this study was to devise a sustainable biological program suited for the research environment in ... Read more >>

Int J Radiat Biol (International journal of radiation biology)
[2018, 94(7):685-693]

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Twenty years of FISH-based translocation analysis for retrospective ionizing radiation biodosimetry.

Eric Grégoire, Laurence Roy, Valérie Buard, Martine Delbos, Valérie Durand, Cécile Martin-Bodiot, Pascale Voisin, Irène Sorokine-Durm, Aurélie Vaurijoux, Philippe Voisin, Céline Baldeyron, Joan Francesc Barquinero,

PURPOSE:The fluorescent in situ hybridization (FISH) technique, which easily detects reciprocal translocations, is currently used to estimate doses in retrospective biological dosimetry, after suspected accidental overexposure to ionizing radiation (IR). This study of 42 cases aimed to verify the appropriateness of this assay for radiation dose reconstruction, compared to the ... Read more >>

Int. J. Radiat. Biol. (International journal of radiation biology)
[2018, 94(3):248-258]

Cited: 1 time

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Continuous 900-megahertz electromagnetic field applied in middle and late-adolescence causes qualitative and quantitative changes in the ovarian morphology, tissue and blood biochemistry of the rat.

Derya Öztürk Okatan, Haydar Kaya, Yüksel Aliyazıcıoğlu, Selim Demir, Serdar Çolakoğlu, Ersan Odacı,

PURPOSE:The purpose of this study was to use histological and biochemical methods in order to evaluate changes taking place in the ovarian of rats exposed to the effect of a 900-megahertz (MHz) electromagnetic field (EMF) in middle and late adolescence. MATERIALS AND METHODS:Twenty-four 34-d-old female Sprague-Dawley rats were assigned equally ... Read more >>

Int. J. Radiat. Biol. (International journal of radiation biology)
[2018, 94(2):186-198]

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Nano alterations of membrane structure on both γ-irradiated and stored human erythrocytes.

Mónica Alessandra Acosta-Elías, Alexel Jesús Burgara-Estrella, J Andre-I Sarabia-Sainz, Erika Silva-Campa, Aracely Angulo-Molina, Karla Josefina Santacruz-Gómez, Beatriz Castaneda, Diego Soto-Puebla, Ana Irene Ledesma-Osuna, Rodrigo Melendrez-Amavizca, Martín Pedroza-Montero,

Storage and ionizing radiation of human red blood cells (RBC) produce alterations on RBC membranes and modify their normal shape and functionality. We investigated early morphological and biochemical changes in RBC due to those stressing agents at the nanoscale level and their impact on blood quality.Whole blood samples from healthy ... Read more >>

Int. J. Radiat. Biol. (International journal of radiation biology)
[2017, 93(12):1306-1311]

Cited: 2 times

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Molecular efficacy of radio- and chemotherapy sequences from direct DNA damage measurements.

Yanfang Dong, Yunfeng Chen, Limei Zhou, Yu Shao, Xianzhi Fu, Yi Zheng,

To investigate the molecular aspects of the synergy between ionizing radiation and platinum (Pt) chemotherapeutic agents in cancer treatment with chemoradiation therapy (CRT) by measuring damages induced by low-energy electrons (LEE) to DNA bound to cisplatin. LEE are produced abundantly by any type of ionizing radiation and cisplatin represents a ... Read more >>

Int. J. Radiat. Biol. (International journal of radiation biology)
[2017, 93(11):1274-1282]

Cited: 1 time

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Gamma irradiation of medicinally important plants and the enhancement of secondary metabolite production.

P Vivek Vardhan, Lata I Shukla,

The profitable production of some important plant-based secondary metabolites (ginsenosides, saponins, camptothecin, shikonins etc.) in vitro by gamma irradiation is a current area of interest. We reviewed different types of secondary metabolites, their mode of synthesis and effect of γ-radiation on their yield for different plants, organs and in vitro ... Read more >>

Int. J. Radiat. Biol. (International journal of radiation biology)
[2017, 93(9):967-979]

Cited: 2 times

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Molecular dissection of the response of the rice Systemic Acquired Resistance Deficient 1 (SARD1) gene to different types of ionizing radiation.

In Jung Jung, Jung Eun Hwang, Sung Min Han, Dong Sub Kim, Joon-Woo Ahn, Hong-Il Choi, Soon-Jae Kwon, Si-Yong Kang, Jin-Baek Kim,

Exposure to ionizing radiation induces plant defenses by regulating the expression of response genes. The systemic acquired resistance deficient 1 (SARD1) is a key gene in plant defense response. In this study, the function of Oryza sativa SARD1 (OsSARD1) was investigated after exposure of seeds/plants to ionizing radiation, jasmonic acid ... Read more >>

Int. J. Radiat. Biol. (International journal of radiation biology)
[2017, 93(7):717-725]

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Induction of interleukin-1β by mouse mammary tumor irradiation promotes triple negative breast cancer cells invasion and metastasis development.

Gina Bouchard, Hélène Therriault, Rachel Bujold, Caroline Saucier, Benoit Paquette,

Radiotherapy increases the level of inflammatory cytokines, some of which are known to promote metastasis. In a mouse model of triple negative breast cancer (TNBC), we determined whether irradiation of the mammary tumor increases the level of key cytokines and favors the development of lung metastases.D2A1 TNBC cells were implanted ... Read more >>

Int. J. Radiat. Biol. (International journal of radiation biology)
[2017, 93(5):507-516]

Cited: 7 times

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Modification of p21 level and cell cycle distribution by 50 Hz magnetic fields in human SH-SY5Y neuroblastoma cells.

Jukka Luukkonen, Anne Höytö, Miiko Sokka, Anu Liimatainen, Juhani Syväoja, Jukka Juutilainen, Jonne Naarala,

In our previous studies, exposure to extremely low frequency (ELF) magnetic fields (MF) altered responses to DNA damage caused by menadione. The aim of this study was to evaluate possible ELF MF induced changes in proteins involved in DNA damage responses and in cell cycle distribution.Based on our previous studies, ... Read more >>

Int. J. Radiat. Biol. (International journal of radiation biology)
[2017, 93(2):240-248]

Cited: 7 times

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RENEB accident simulation exercise.

Beata Brzozowska, Elizabeth Ainsbury, Annelot Baert, Lindsay Beaton-Green, Leonardo Barrios, Joan Francesc Barquinero, Celine Bassinet, Christina Beinke, Anett Benedek, Philip Beukes, Emanuela Bortolin, Iwona Buraczewska, Christopher Burbidge, Andrea De Amicis, Cinzia De Angelis, Sara Della Monaca, Julie Depuydt, Stefania De Sanctis, Katalin Dobos, Mercedes Moreno Domene, Inmaculada Domínguez, Eva Facco, Paola Fattibene, Monika Frenzel, Octávia Monteiro Gil, Géraldine Gonon, Eric Gregoire, Gaëtan Gruel, Valeria Hadjidekova, Vasiliki I Hatzi, Rositsa Hristova, Alicja Jaworska, Enikő Kis, Maria Kowalska, Ulrike Kulka, Florigio Lista, Katalin Lumniczky, Wilner Martínez-López, Roberta Meschini, Simone Moertl, Jayne Moquet, Mihaela Noditi, Ursula Oestreicher, Manuel Luis Orta Vázquez, Valentina Palma, Gabriel Pantelias, Alegria Montoro Pastor, Clarice Patrono, Laure Piqueret-Stephan, Maria Cristina Quattrini, Elisa Regalbuto, Michelle Ricoul, Sandrine Roch-Lefevre, Laurence Roy, Laure Sabatier, Lucia Sarchiapone, Natividad Sebastià, Sylwester Sommer, Mingzhu Sun, Yumiko Suto, Georgia Terzoudi, Francois Trompier, Anne Vral, Ruth Wilkins, Demetre Zafiropoulos, Albrecht Wieser, Clemens Woda, Andrzej Wojcik,

The RENEB accident exercise was carried out in order to train the RENEB participants in coordinating and managing potentially large data sets that would be generated in case of a major radiological event.Each participant was offered the possibility to activate the network by sending an alerting email about a simulated ... Read more >>

Int. J. Radiat. Biol. (International journal of radiation biology)
[2017, 93(1):75-80]

Cited: 7 times

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Low-dose hyper-radiosensitivity in human hepatocellular HepG2 cells is associated with Cdc25C-mediated G2/M cell cycle checkpoint control.

Jun Xue, Yan Zong, Pin-Dong Li, Li-Xia Wang, Yun-Qiao Li, Yan-Feng Niu,

Although the significance of cell cycle checkpoints in overcoming low-dose hyper-radiosensitivity (HRS) has been proposed, the underlying mechanism of HRS in human hepatocellular cells remains unclear. Therefore, the aim of this study was to characterize HRS inhuman hepatocellular HepG2 cells and to explore the molecular mechanism(s) mediating this response.HepG2 cells ... Read more >>

Int. J. Radiat. Biol. (International journal of radiation biology)
[2016, 92(10):543-547]

Cited: 1 time

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Use of a DNA film on a self-assembled monolayer for investigating the physical process of DNA damage induced by core electron ionization.

Ayumi Narita, Kentaro Fujii, Yuji Baba, Iwao Shimoyama,

A novel two-layer sample composed of a deoxyribonucleic acid (DNA) film and self-assembled monolayer (SAM) was prepared on an inorganic surface to mimic the processes in which DNA is damaged by soft X-ray irradiation.A mercaptopropyltrimethoxysilane (MPTS) SAM was formed on a sapphire surface, then oligonucleotide (OGN) molecules were adsorbed on ... Read more >>

Int. J. Radiat. Biol. (International journal of radiation biology)
[2016, 92(11):733-738]

Cited: 0 times

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Effect of extremely low frequency electromagnetic fields on bacterial membrane.

Sule Oncul, Esra M Cuce, Burak Aksu, Ayse Inhan Garip,

The effect of extremely low frequency electromagnetic fields (ELF-EMF) on bacteria has attracted attention due to its potential for beneficial uses. This research aimed to determine the effect of ELF-EMF on bacterial membrane namely the membrane potential, surface potential, hydrophobicity, respiratory activity and growth.Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli ... Read more >>

Int. J. Radiat. Biol. (International journal of radiation biology)
[2016, 92(1):42-49]

Cited: 3 times

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Cyclooxygenase-2 inhibitor prevents radiation-enhanced infiltration of F98 glioma cells in brain of Fischer rat.

Guillaume Desmarais, Gabriel Charest, David Fortin, Rachel Bujold, David Mathieu, Benoit Paquette,

Radiation induces a neuro-inflammation that is characterized by the expression of genes known to increase the invasion of cancer cells. In Fischer rats, brain irradiation increases the infiltration of cancer cells and reduced the median survival of the animals. In this study, we have determined whether these adverse effects of ... Read more >>

Int. J. Radiat. Biol. (International journal of radiation biology)
[2015, 91(8):624-633]

Cited: 10 times

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Response to Hein and Schubauer-Berigan.

Joey Y Zhou,

Int. J. Radiat. Biol. (International journal of radiation biology)
[2015, 91(11):911-912]

Cited: 0 times

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Alternative models for estimating the radiotherapy retreatment dose for the spinal cord.

Bleddyn Jones, John W Hopewell,

PURPOSE: To review the available experimental animal and patient data on response of the spinal cord to re-irradiation in order to identify appropriate data sets to investigate the clinical potential of models that would allow evaluation of the increase in the retreatment dose with elapsed time from the initial exposure. ... Read more >>

Int. J. Radiat. Biol. (International journal of radiation biology)
[2014, 90(9):731-741]

Cited: 4 times

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A moderate protective effect of quercetin against γ-irradiation- and storage-induced oxidative damage in red blood cells for transfusion.

Halina Malgorzata Zbikowska, Adam Antosik, Magdalena Szejk, Michal Bijak, Pawel Nowak,

PURPOSE: To investigate the extent of γ-irradiation-induced oxidative membrane damage and antioxidant activity of quercetin in long-term, cold stored (4°C) acid-citrate-dextrose- preserved human red blood cells (RBC). MATERIALS AND METHODS: The extracellular activity of lactate dehydrogenase (LDH) was measured to assess RBC membrane integrity. Lipid peroxidation and reduced glutathione (GSH) ... Read more >>

Int. J. Radiat. Biol. (International journal of radiation biology)
[2014, 90(12):1201-1210]

Cited: 6 times

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Lifetime of the unpaired electron species in calf thymus DNA thin films induced by nitrogen and oxygen K-shell photoabsorption.

Toshitaka Oka, Akinari Yokoya, Kentaro Fujii,

To study the lifetime of the short-lived unpaired electron species induced in a calf thymus DNA film by soft X-rays in the energy regions around nitrogen and oxygen K-edge.Dry calf thymus DNA films were measured by electron paramagnetic resonance (EPR) spectrometer during the monochromatic soft X-ray irradiation provided from a ... Read more >>

Int. J. Radiat. Biol. (International journal of radiation biology)
[2012, 88(12):884-887]

Cited: 0 times

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Fusion of images in multistep analysis of neovascularisation.

Sergey V Tokalov, Andrij M Abramyuk,

PURPOSE: The aim of our study was to develop a method for the fusion of images received after repeated staining of the same sample taking into account spatial differences between the images. MATERIAL AND METHODS: A method of objective fusion performance was investigated on the images receiving during multistep staining ... Read more >>

Int. J. Radiat. Biol. (International journal of radiation biology)
[2009, 85(9):747-751]

Cited: 0 times

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Ultrafractionation in A7 human malignant glioma in nude mice.

M Krause, F Hessel, J Wohlfarth, D Zips, C Hoinkis, H Foest, C Petersen, S C Short, M C Joiner, M Baumann,

PURPOSE:Low-dose hyperradiosensitivity (HRS) has been demonstrated in numerous cell lines in vitro, including a number of radioresistant human malignant glioma cell lines such as A7. The aim of our experiment was to show whether HRS can be exploited by using ultrafractionated irradiation (UF) to improve local control of A7 tumours ... Read more >>

Int. J. Radiat. Biol. (International journal of radiation biology)
[2003, 79(6):377-383]

Cited: 15 times

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Problems in scoring radiation-induced chromatid breaks. Comments on the paper: The XRCC2 human repair gene influences recombinational rearrangements leading to chromatid breaks.

J Thacker, C S Griffin,

Int. J. Radiat. Biol. (International journal of radiation biology)
[2002, 78(10):945-7; author reply 947-8]

Cited: 1 time

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Modulation of the clastogenic activity of gamma-irradiation in buthionine sulphoximine-mediated glutathione depleted mammalian cells.

A Chattopadhyay, S Deb, A Chatterjee,

PURPOSE:Chromosome aberrations (CA) were used as an end-point to investigate the effect of buthionine sulphoximine (BSO), a potent glutathione-depleting agent, on the radiosensitivity of mammalian cells. The aim was to obtain information about the role of glutathione (GSH) in physicochemical and biochemical processes in irradiated cells. MATERIALS AND METHODS:CA were ... Read more >>

Int. J. Radiat. Biol. (International journal of radiation biology)
[1999, 75(10):1283-1291]

Cited: 15 times

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