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Journal Int J Ophthalmol

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Multiple excimer laser phototherapeutic keratectomies for Avellino corneal dystrophy: a case report.

Chihiro Koiwa, Satoru Nakatani, Takenori Inomata, Masahiro Yamaguchi, Satoshi Iwamoto, Akira Murakami,

Int J Ophthalmol (International journal of ophthalmology)
[2020, 13(5):841-844]

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Laser therapy versus intravitreal injection of anti-VEGF agents in monotherapy of ROP: a Meta-analysis.

Shi-Dan Wang, Guo-Ming Zhang, ,

AIM:To compare the efficacy and safety between laser therapy and anti-vascular endothelial growth factor (VEGF) agents intravitreal injection monotherapy in type-1 retinopathy of prematurity (ROP) and aggressive posterior retinopathy of prematurity (APROP). METHODS:A systematic literature search was performed in PubMed, Cochrane Library, and Embase for original comparable studies. We included ... Read more >>

Int J Ophthalmol (International journal of ophthalmology)
[2020, 13(5):806-815]

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Comparison of choroidal thickness in high myopic eyes after FS-LASIK versus implantable collamer lens implantation with swept-source optical coherence tomography.

Jing Zhang, Fang-Lin He, Yan Liu, Xian-Qun Fan,

AIM:To investigate the changes in choroidal thickness (CT) in high myopic eyes after femtosecond laser-assisted in situ keratomileusis (FS-LASIK) surgery or central hole implantable collamer lens (ICL V4c) implantation using swept-source optical coherence tomography (SS-OCT). METHODS:We examined the right eyes of 116 patients with high myopia who were candidates for ... Read more >>

Int J Ophthalmol (International journal of ophthalmology)
[2020, 13(5):773-781]

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Diffractive multifocal intraocular lens implantation in patients with monofocal intraocular lens in the contralateral eye.

Jae Yong Kim, Yunhan Lee, Hun Jae Won, Hyerin Jeong, Jin Hyoung Park, Myoung Joon Kim, Hungwon Tchah,

AIM:To evaluate clinical outcomes of unilateral implantation of a diffractive multifocal intraocular lens (IOL) in patients with contralateral monofocal IOL. METHODS:Twenty-two patients who already had implantation of a monofocal IOL in unilateral eye underwent implantation of a diffractive multifocal IOL in contralateral eye were enrolled. After 1, 6, and 12mo, ... Read more >>

Int J Ophthalmol (International journal of ophthalmology)
[2020, 13(5):737-743]

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The anti-inflammatory regulation of calcitonin gene-related peptide in mouse Aspergillus fumigatus keratitis.

Ming Xu, Cui Li, Gui-Qiu Zhao, Jing Lin, Min Yin, Heng-Rui Zheng, Li Zhang, Meng-Qi Wu,

AIM:To analyze the impact of calcitonin gene-related peptide (CGRP) in mouse keratitis after Aspergillus fumigatus (A. fumigatus) infection. METHODS:C57BL/6 mice were treated subconjunctivally with different concentrations of exogenous CGRP, and BALB/c mice were treated with CGRP8-37 (a CGRP antagonist) before corneas were infected with A. fumigatus. The cornea was assessed ... Read more >>

Int J Ophthalmol (International journal of ophthalmology)
[2020, 13(5):701-707]

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Clinical efficacy of Ahmed glaucoma valve implantation combined with 23-gauge vitrectomy for medically uncontrolled neovascular glaucoma with proliferative diabetic retinopathy.

Zhong-Jing Lin, Zheng-Hua Chen, Shou-Yue Huang, Jun Sun, Xi Shen, Yi-Sheng Zhong,

AIM:To describe the clinical results of combined Ahmed valve implantation and 23-gauge vitrectomy for medically uncontrolled neovascular glaucoma (NVG) secondary to proliferative diabetic retinopathy (PDR). METHODS:The medical records of medically uncontrolled NVG patients with PDR who underwent Ahmed valve implantation and 23-gauge vitrectomy between March 2016 and December 2018 were ... Read more >>

Int J Ophthalmol (International journal of ophthalmology)
[2020, 13(5):832-836]

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Relationship between intraocular pressure and parameters of obesity in ocular hypertension.

Min Won Ahn, Ji Woong Lee, Jong Hoon Shin, Jong Soo Lee,

AIM:To evaluate the correlation between intraocular pressure (IOP) and various obesity-related health factors in patients with ocular hypertension in Korea. METHODS:A total of 40 850 subjects underwent age, sex, body weight, and height assessments and automated multiphasic tests, including non-contact tonometry, automated perimetry, fundus photography, systolic/diastolic blood pressure measurement, and ... Read more >>

Int J Ophthalmol (International journal of ophthalmology)
[2020, 13(5):794-800]

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Analysis of the rates of emulsification in intraocular silicone oil tamponades of differing viscosities.

Xiu-Juan Zhao, Ning-Ning Tang, Yu Lian, Bing-Qian Liu, Yong-Hao Li, Lin Lu,

AIM:To investigate the rates of emulsification in silicone oil (SO) tamponades of differing viscosities used during pars plana vitrectomy (PPV) in the treatment of complicated vitreoretinal diseases. METHODS:This study was a prospective randomized clinical trial. Totally 290 cases with greater likelihoods of secondary detachment were included and randomly grouped into ... Read more >>

Int J Ophthalmol (International journal of ophthalmology)
[2020, 13(5):761-765]

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Biocompatibility of polyetheretherketone for the treatment of orbital bone defects.

Rui-Dong Gu, Fan Xiao, Lin Wang, Kai-Jian Sun, Lin-Lin Chen,

AIM:To investigate the biocompatibility and therapeutic effects of polyetheretherketone (PEEK) on recovery of a rabbit orbital defect. METHODS:Totally 16 New Zealand rabbits were used to establish an orbital bone defect model and then randomly divided into two groups. PEEK was implanted in the experimental group. The control group was blank, ... Read more >>

Int J Ophthalmol (International journal of ophthalmology)
[2020, 13(5):725-730]

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Intracameral 5-fluorouracil and viscous dispersive viscoelastic for diffuse epithelial downgrowth management in aphakia.

Santiago Montolío-Marzo, Ester Fernández-López, Jose Vicente Piá-Ludeña, Juan María Davó-Cabrera, Enrique Antonio Alfonso-Muñoz, Cristina Peris-Martínez,

Int J Ophthalmol (International journal of ophthalmology)
[2020, 13(5):845-847]

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Progress in the basic and clinical research on the Schlemm's canal.

Le-Ying Wang, Guan-Yu Su, Zhen-Yu Wei, Zi-Jun Zhang, Qing-Feng Liang,

Glaucoma is a leading cause of irreversible blindness in the world. Intraocular pressure (IOP) plays a key role in glaucoma development and progression. Schlemm's canal (SC), an important structure of the anterior chamber angle, regulates the flow of aqueous humor and maintains IOP. Because of its special function of aqueous ... Read more >>

Int J Ophthalmol (International journal of ophthalmology)
[2020, 13(5):816-821]

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Changes in corneal biomechanics and intraocular pressure following Femto-LASIK using Goldman applanation tonometry and ocular response analyzer.

Ahmed Yassin Hemida, Omar M Said, Asser A E Abdel-Meguid, Mohammed Iqbal, Amani E Badawi,

AIM:To compare intraocular pressure (IOP) measurements before and after laser in situ keratomileusis (LASIK) with a femtosecond laser for flap creation using ocular response analyzer (ORA) and Goldmann applanation tonometry, and to identify factors that may influence the preoperative and postoperative IOP. METHODS:A prospective study conducted on myopic patients who ... Read more >>

Int J Ophthalmol (International journal of ophthalmology)
[2020, 13(5):782-787]

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Optical coherence tomography angiography of the peripapillary region and macula in normal, primary open angle glaucoma, pseudoexfoliation glaucoma and ocular hypertension eyes.

Helin Ceren Köse, Oya Tekeli,

AIM:To evaluate and compare the peripapillary and retinal vasculature changes in primary open angle glaucoma (POAG), pseudoexfoliation glaucoma (PXG), ocular hypertension (OHT) and normal eyes using optical coherence tomography angiography (OCTA). METHODS:A total of 114 POAG, PXG and OHT eyes of 60 patients and 46 eyes of 23 healthy control ... Read more >>

Int J Ophthalmol (International journal of ophthalmology)
[2020, 13(5):744-754]

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High-mobility group box1 as an amplifier of immune response and target for treatment in Aspergillus fumigatus keratitis.

Meng-Qi Wu, Cui Li, Li-Na Zhang, Jing Lin, Kun He, Ya-Wen Niu, Cheng-Ye Che, Nan Jiang, Jia-Qian Jiang, Gui-Qiu Zhao,

AIM:To determine the roles of high-mobility group box1 (HMGB1) in pro-inflammation, host immune response and its potential target for treatment in Aspergillus fumigatus (A.fumigatus) keratitis. METHODS:Expression of HMGB1 was tested in C57BL/6 normal and infected corneas. Dual immunostaining tested co-expression of HMGB1 with TLR4 or LOX-1. C57BL/6 mice were pretreated ... Read more >>

Int J Ophthalmol (International journal of ophthalmology)
[2020, 13(5):708-717]

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Combine deep lamellar endothelial keratoplasty and anterior lamellar keratoplasty with limbal allograft for severe corneal injury: a case report.

Yi Liu, Yu-Qing Deng, Jin Yuan,

Int J Ophthalmol (International journal of ophthalmology)
[2020, 13(5):837-840]

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Prevalence of heterophoria in a population of school children in central China: the Anyang Childhood Eye Study.

Jie Hong, Jing Fu, Yi-Di Wang, Bo-Wen Zhao, Lei Li,

AIM:To investigate the prevalence of heterophoria and the relationship between heterophoria and refractive error in a school-based study conducted in central China. METHODS:A total of 2363 7th-grade children were recruited into the cross-sectional school-based Anyang Childhood Eye Study (ACES) by cluster sampling method. Heterophoria was examined using alternate cover and ... Read more >>

Int J Ophthalmol (International journal of ophthalmology)
[2020, 13(5):801-805]

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Foveal pit morphological changes in asymptomatic carriers of the G11778A mutation with Leber's hereditary optic neuropathy.

Xin-Ting Liu, Mei-Xiao Shen, Chong Chen, Sheng-Hai Huang, Xi-Ran Zhuang, Qing-Kai Ma, Qi Chen, Fan Lu, Yi-Min Yuan,

AIM:To investigate the foveal pit morphology changes in unaffected carriers and affected Leber's hereditary optic neuropathy (LHON) patients with the G11778A mutation from one family. METHODS:This study was a prospective cross-sectional study. Both eyes from 16 family members (age from 9 to 47y) with the G11778A mutation were analyzed and ... Read more >>

Int J Ophthalmol (International journal of ophthalmology)
[2020, 13(5):766-772]

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Analysis of choroidal morphology and comparison of imaging findings of subtypes of polypoidal choroidal vasculopathy: a new classification system.

Zi-Yang Liu, Bing Li, Song Xia, You-Xin Chen,

AIM:To classify polypoidal choroidal vasculopathy (PCV) into 2 subtypes based on the subfoveal choroidal thickness (SFCT) and to further evaluate their multimodal image features. METHODS:A retrospective observational case series study. Sixty-four eyes of 64 patients with PCV were enrolled and classified into 2 groups based on SFCT (thick-choroid group/thin-choroid group). ... Read more >>

Int J Ophthalmol (International journal of ophthalmology)
[2020, 13(5):731-736]

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Cross-talk between microRNA-let7c and transforming growth factor-β2 during epithelial-to-mesenchymal transition of retinal pigment epithelial cells.

Qu-Zhen Deji, Feng Yan, Wang-Dui Zhaba, Ya-Jun Liu, Jie Yin, Zhen-Ping Huang,

AIM:To explore the roles of microRNA-let7c (miR-let7c) and transforming growth factor-β2 (TGF-β2) and cellular signaling during epithelial-to-mesenchymal transition (EMT) of retinal pigment epithelial cells. METHODS:Retinal pigment epithelial (ARPE-19) cells were cultured with no serum for 12h, and then with recombinant human TGF-β2 for different lengths of time. ARPE-19 cells were ... Read more >>

Int J Ophthalmol (International journal of ophthalmology)
[2020, 13(5):693-700]

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Comment on "Microvascular changes after conbercept therapy in central retinal vein occlusion analyzed by optical coherence tomography angiography".

Dan Călugăru, Mihai Călugăru,

Int J Ophthalmol (International journal of ophthalmology)
[2020, 13(5):848-850]

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Internal limiting membrane flap technique in macular hole surgery.

Qian Xu, Jie Luan,

Vitrectomy combined with internal limiting membrane (ILM) peeling is popular for the treatment of macular hole (MH). However, the improvements of MH closure rate and postoperative visual acuity are not satisfactory especially in large and refractory MHs. Currently, the ILM flap technique has gradually been applied for the treatment of ... Read more >>

Int J Ophthalmol (International journal of ophthalmology)
[2020, 13(5):822-831]

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Relationship between diabetes mellitus and cataract in Hungary.

Anita Pék, Dorottya Szabó, Gábor László Sándor, Gábor Tóth, András Papp, Zoltán Zsolt Nagy, Hans Limburg, János Németh,

AIM:To examine the coexistence of diabetes mellitus (DM) and cataract in Hungary. The effects of DM on the cataract surgical results were also in the focus of analysis. METHODS:Statistical data analysis of the results of the Rapid Assessment of Avoidable Blindness with Diabetic Retinopathy (RAAB+DR) module conducted in Hungary in ... Read more >>

Int J Ophthalmol (International journal of ophthalmology)
[2020, 13(5):788-793]

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Internal limiting membrane dragging and peeling: a modified technique for macular holes closure surgery.

Jie Peng, Li-Hua Zhang, Chun-Li Chen, Jing-Jing Liu, Xiu-Yu Zhu, Pei-Quan Zhao,

AIM:To introduce a modified technique of internal limiting membrane (ILM) centripetal dragging and peeling to treat idiopathic macular hole (IMH) and to observe the ILM-retina adhesive forces. METHODS:Twenty-six consecutive patients with stage 3 to 4 IMH and followed up at least six months were enrolled. All patients underwent complete par ... Read more >>

Int J Ophthalmol (International journal of ophthalmology)
[2020, 13(5):755-760]

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miRNA-145/miRNA-205 inhibits proliferation and invasion of uveal melanoma cells by targeting NPR1/CDC42.

Yang Li, Jing-Ting Luo, Yue-Ming Liu, Wen-Bin Wei,

AIM:To investigate the role of microRNA-145 (miRNA-145) and microRNA-205 (miRNA-205) in proliferation and invasion of uveal melanoma (UM) cells. METHODS:The expression level of miRNA-145 and miRNA-205 from samples of UM patients were determined by real-time polymerase chain reaction (RT-PCR). The growth and invasion inhibitory effects were observed by the transfection ... Read more >>

Int J Ophthalmol (International journal of ophthalmology)
[2020, 13(5):718-724]

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Intraoperative optical coherence tomography findings during surgery for optic disc pit-associated maculopathy.

Hyun Goo Kang, Sung Eun Park, Eun Young Choi, Sung Chul Lee, Min Kim,

Int J Ophthalmol (International journal of ophthalmology)
[2020, 13(4):684-686]

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