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Diagnostic radiological examinations and risk of intracranial tumours in adults-findings from the Interphone Study.

Anssi Auvinen, Elisabeth Cardis, Maria Blettner, Monika Moissonnier, Siegal Sadetzki, Graham Giles, Christoffer Johansen, Anthony Swerdlow, Angus Cook, Sarah Fleming, Gabriele Berg-Beckhoff, Ivano Iavarone, Marie-Elise Parent, Alistair Woodward, Tore Tynes, Mary McBride, Dan Krewski, Maria Feyching, Toru Takebayashi, Bruce Armstrong, Martine Hours, Jack Siemiatycki, Susanna Lagorio, Signe Benzon Larsen, Minouk Schoemaker, Lars Klaeboe, Stefan Lönn, Joachim Schüz, ,

<h4>Background</h4>Exposure to high doses of ionizing radiation is among the few well-established brain tumour risk factors. We used data from the Interphone study to evaluate the effects of exposure to low-dose radiation from diagnostic radiological examinations on glioma, meningioma and acoustic neuroma risk.<h4>Methods</h4>Brain tumour cases (2644 gliomas, 2236 meningiomas, 1083 ... Read more >>

Int J Epidemiol (International journal of epidemiology)
[2021, :]

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Prenatal exposure to nitrofurantoin and risk of childhood leukaemia: a registry-based cohort study in four Nordic countries.

Sarah Hjorth, Anton Pottegård, Anne Broe, Caroline H Hemmingsen, Maarit K Leinonen, Marie Hargreave, Ulrika Nörby, Hedvig Nordeng,

<h4>Background</h4>Studies have suggested increased risks of childhood leukaemia after prenatal exposure to antibiotics, particularly nitrofurantoin. However, these findings may be related to the underlying maternal infection. This multinational study aimed to investigate the association between prenatal nitrofurantoin exposure and childhood leukaemia while accounting for maternal infection.<h4>Methods</h4>In a population-based cohort study ... Read more >>

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Data Resource Profile: The Alberta Adolescent and Young Adult Cancer Survivor Study.

Ruth L Diaz, Stephana J Moss, Khalid B Amin, Andrew S Harper, Jan-Willem Henning, Natalie Logie, Fiona Schulte, Sarah J McKillop, Michael J Lang, Miranda M Fidler-Benaoudia,

Int J Epidemiol (International journal of epidemiology)
[2021, :]

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Pre-eclampsia and risk of early-childhood asthma: a register study with sibling comparison and an exploration of intermediate variables.

Kristine Kjer Byberg, Cecilia Lundholm, Bronwyn K Brew, Gustaf Rejnö, Catarina Almqvist,

We aimed to study whether pre-eclampsia is associated with childhood asthma, allergic and non-allergic asthma, accounting for family factors and intermediate variables. The study population comprised 779 711 children born in 2005-2012, identified from Swedish national health registers (n = 14 823/7410 exposed to mild/moderate and severe pre-eclampsia, respectively). We ... Read more >>

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[2021, :]

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Cohort Profile: Regional Ethnic Cohort Study in Northwest China.

Chao Li, Yezhou Liu, Guoshuai Shi, Baibing Mi, Lingxia Zeng, Qiang Li, Yuan Shen, Yaling Zhao, Leilei Pei, Yijun Kang, Shengbing Xiao, Xin Liu, Jianghong Dai, Yuhong Zhang, Xinhua Wang, Xiaojie Wang, Duolao Wang, Hong Yan, Shaonong Dang,

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[2021, :]

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Cohort Profile: The Ovarian Cancer Cohort Consortium (OC3).

Mary K Townsend, Britton Trabert, Renée T Fortner, Alan A Arslan, Julie E Buring, Brian D Carter, Graham G Giles, Sarah R Irvin, Michael E Jones, Rudolf Kaaks, Victoria A Kirsh, Synnove F Knutsen, Woon-Puay Koh, James V Lacey, Hilde Langseth, Susanna C Larsson, I-Min Lee, María Elena Martínez, Melissa A Merritt, Roger L Milne, Katie M O'Brien, Michael J Orlich, Julie R Palmer, Alpa V Patel, Ulrike Peters, Jenny N Poynter, Kim Robien, Thomas E Rohan, Lynn Rosenberg, Sven Sandin, Dale P Sandler, Leo J Schouten, V Wendy Setiawan, Anthony J Swerdlow, Giske Ursin, Piet A van den Brandt, Kala Visvanathan, Elisabete Weiderpass, Alicja Wolk, Jian-Min Yuan, Anne Zeleniuch-Jacquotte, Shelley S Tworoger, Nicolas Wentzensen,

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[2021, :]

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Growing urban and rural inequalities: looking at the heart to reduce the gap.

Martin O'Flaherty,

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[2021, :]

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Corrigendum to: 1513 Foodborne Outbreak in the Central Prison, Amanat Al-Asimah, Yemen-October, 2020.

Salwa Al-Eryani, Mohammed Qeran, Labibah Saeed, Yasser Ghaleb,

Int J Epidemiol (International journal of epidemiology)
[2021, :]

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How blood pressure predicts frailty transitions in older adults in a population-based cohort study: a multi-state transition model.

Daniela Anker, Cristian Carmeli, Marcel Zwahlen, Nicolas Rodondi, Valérie Santschi, Yves Henchoz, Christina Wolfson, Arnaud Chiolero,

<h4>Background</h4>Low blood pressure (BP) is associated with frailty in older adults. Our aim was to explore how BP predicts transitions between frailty states.<h4>Methods</h4>We used data from the Lausanne cohort Lc65+, a population-based cohort of older adults randomly drawn from a population registry in Switzerland, in 2004, 2009 and 2014. BP ... Read more >>

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[2021, :]

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Are Greenland, Ioannidis and Poole opposed to the Cornfield conditions? A defence of the E-value.

Tyler J VanderWeele,

Int J Epidemiol (International journal of epidemiology)
[2021, :]

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Cohort Profile update: The Concord Health and Ageing in Men Project (CHAMP).

Saman Khalatbari-Soltani, Fiona M Blyth, Vasi Naganathan, David G Le Couteur, David J Handelsman, Markus J Seibel, Vasant Hirani, F A Clive Wright, Louise M Waite, Robert G Cumming,

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[2021, :]

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Quantifying impacts of the COVID-19 pandemic through life-expectancy losses: a population-level study of 29 countries.

José Manuel Aburto, Jonas Schöley, Ilya Kashnitsky, Luyin Zhang, Charles Rahal, Trifon I Missov, Melinda C Mills, Jennifer B Dowd, Ridhi Kashyap,

<h4>Background</h4>Variations in the age patterns and magnitudes of excess deaths, as well as differences in population sizes and age structures, make cross-national comparisons of the cumulative mortality impacts of the COVID-19 pandemic challenging. Life expectancy is a widely used indicator that provides a clear and cross-nationally comparable picture of the ... Read more >>

Int J Epidemiol (International journal of epidemiology)
[2021, :]

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Outlier.

Vandana Sharma,

Int J Epidemiol (International journal of epidemiology)
[2021, :]

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Cohort Profile: The 1978-79 Ribeirao Preto (Brazil) birth cohort study.

Marco Antônio Barbieri, Alexandre Archanjo Ferraro, Vanda Maria Ferreira Simões, Marcelo Zubaran Goldani, Viviane Cunha Cardoso, Antonio Augusto Moura da Silva, Heloisa Bettiol,

Int J Epidemiol (International journal of epidemiology)
[2021, :]

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A limitation of genetic epidemiological analysis when associations are genuinely J-shaped illustrated using a prospective study of alcohol consumption and vascular disease.

Chris Frost, Nicholas Wald,

Int J Epidemiol (International journal of epidemiology)
[2021, :]

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Interpreting Mendelian-randomization estimates of the effects of categorical exposures such as disease status and educational attainment.

Laurence J Howe, Matthew Tudball, George Davey Smith, Neil M Davies,

<h4>Background</h4>Mendelian randomization has been previously used to estimate the effects of binary and ordinal categorical exposures-e.g. Type 2 diabetes or educational attainment defined by qualification-on outcomes. Binary and categorical phenotypes can be modelled in terms of liability-an underlying latent continuous variable with liability thresholds separating individuals into categories. Genetic variants ... Read more >>

Int J Epidemiol (International journal of epidemiology)
[2021, :]

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Independent effects of adiposity measures on risk of atrial fibrillation in men and women: a study of 0.5 million individuals.

C Fielder Camm, Ben Lacey, M Sofia Massa, Adam Von Ende, Parag Gajendragadkar, Alexander Stiby, Elsa Valdes-Marquez, Sarah Lewington, Rohan Wijesurendra, Sarah Parish, Barbara Casadei, Jemma C Hopewell,

<h4>Background</h4>Atrial fibrillation (AF) has a higher prevalence in men than in women and is associated with measures of adiposity and lean mass (LM). However, it remains uncertain whether the risks of AF associated with these measures vary by sex.<h4>Methods</h4>Among 477 904 UK Biobank participants aged 40-69 without prior AF, 23 ... Read more >>

Int J Epidemiol (International journal of epidemiology)
[2021, :]

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Impact of paternal education on epigenetic ageing in adolescence and mid-adulthood: a multi-cohort study in the USA and Mexico.

Brian T Joyce, Tao Gao, Kalsea Koss, Yinan Zheng, Andres Cardenas, Jonathan Heiss, Allan Just, Kai Zhang, Linda van Horn, Norrina Bai Allen, Philip Greenland, Sheldon Cohen, Penny Gordon-Larsen, Colter Mitchell, Sara McLanahan, Lisa Schneper, Daniel Notterman, Sheryl L Rifas-Shiman, Emily Oken, Marie-France Hivert, Robert Wright, Andrea Baccarelli, Donald Lloyd-Jones, Lifang Hou,

<h4>Background</h4>Both parental and neighbourhood socio-economic status (SES) are linked to poorer health independently of personal SES measures, but the biological mechanisms are unclear. Our objective was to examine these influences via epigenetic age acceleration (EAA)-the discrepancy between chronological and epigenetic ages.<h4>Methods</h4>We examined three USA-based [Coronary Artery Risk Disease in Adults ... Read more >>

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[2021, :]

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Circulating levels of maternal vitamin D and risk of ADHD in offspring: results from the Vitamin D Antenatal Asthma Reduction Trial.

Su H Chu, Mengna Huang, Rachel S Kelly, Priyadarshini Kachroo, Augusto A Litonjua, Scott T Weiss, Jessica Lasky-Su,

<h4>Background</h4>Low levels of circulating 25-hydroxy-vitamin D [25(OH)D] have been shown to associate with prevalent attention-deficit/hyperactivity disorder (ADHD), but few studies have examined the association between 25(OH)D during fetal development and risk of childhood ADHD.<h4>Methods</h4>Maternal plasma 25(OH)D was measured at 10-18 and 32-38 weeks of gestation, with sufficiency defined as 25(OH)D ... Read more >>

Int J Epidemiol (International journal of epidemiology)
[2021, :]

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Reproductive factors and gall-bladder cancer, and the effect of common genetic variants on these associations: a case-control study in India.

Sharayu Mhatre, Ben Lacey, Paul Sherliker, Nilanjan Chatterjee, Preetha Rajaraman, Mahesh Goel, Shraddha Patkar, Vikas Ostwal, Prachi Patil, Shailesh V Shrikhande, Garvit Chitkara, Rajendra Badwe, Sarah Lewington, Rajesh Dikshit,

<h4>Background</h4>In India, as elsewhere, the incidence of gall-bladder cancer (GBC) is substantially higher in women than in men. Yet, the relevance of reproductive factors to GBC remains poorly understood.<h4>Methods</h4>We used logistic regression adjusted for age, education and area to examine associations between reproductive factors and GBC risk, using 790 cases ... Read more >>

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[2021, :]

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Use of antidepressants and endometrial-cancer risk: a nationwide nested case-control study.

Cecilie D Sperling, Gitte L Aalborg, Christian Dehlendorff, Søren Friis, Lina S Mørch, Susanne K Kjaer,

<h4>Background</h4>Preclinical studies have suggested that antidepressant drugs may possess antineoplastic properties. In a nationwide case-control study, we examined the association between use of antidepressants and endometrial-cancer risk with a particular focus on selective serotonin reuptake inhibitors (SSRIs).<h4>Methods</h4>From the Danish Cancer Registry, we identified all women with a histologically verified diagnosis ... Read more >>

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[2021, :]

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Solid fuel use, socioeconomic indicators and risk of cardiovascular diseases and all-cause mortality: a prospective cohort study in a rural area of Sichuan, China.

Shuyi Qiu, Xiaofang Chen, Xiaofang Chen, Guojin Luo, Yu Guo, Zheng Bian, Liming Li, Zhengming Chen, Xianping Wu, John S Ji,

<h4>Background</h4>Estimates indicate that household air pollution caused by solid fuel burning accounted for about 1.03 million premature mortalities in China in 2016. In the country's rural areas, more than half the population still relies on biomass fuels and coals for cooking and heating. Understanding the health impact of indoor air ... Read more >>

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Reflection on modern methods: combining weights for confounding and missing data.

Rachael K Ross, Alexander Breskin, Tiffany L Breger, Daniel Westreich,

Inverse probability weights are increasingly used in epidemiological analysis, and estimation and application of weights to address a single bias are well discussed in the literature. Weights to address multiple biases simultaneously (i.e. a combination of weights) have almost exclusively been discussed related to marginal structural models in longitudinal settings ... Read more >>

Int J Epidemiol (International journal of epidemiology)
[2021, :]

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Evidence of large systematic differences between countries in assigning ischaemic heart disease deaths to myocardial infarction: the contrasting examples of Russia and Norway.

Sergey Timonin, Vladimir M Shkolnikov, Evgeny Andreev, Per Magnus, David A Leon,

<h4>Background</h4>There is considerable variation in mortality rates from myocardial infarction (MI) across high-income countries, some of which may be artefactual.<h4>Methods</h4>Time trends in mortality rates from ischaemic heart disease (IHD) and MI were analysed for a set of high-income countries from the end of the 1970s. Using individual-level mortality data from ... Read more >>

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Definition yes, analysis no: a comment on 'analyses of "change scores" do not estimate causal effects in observational data'.

Frank Popham,

Int J Epidemiol (International journal of epidemiology)
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