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Journal Int J Clin Pharm

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A systematic review of pharmacist input to metabolic syndrome screening, management and prevention.

Rana Moustafa Al AdAwi, Derek Stewart, Cristin Ryan, Antonella Pia Tonna,

Background Metabolic syndrome is a cluster of factors that increase the risk of cardiovascular disease and include: diabetes and prediabetes, abdominal obesity, elevated triglycerides, low high-density lipoprotein cholesterol and high blood-pressure. However, the role of the pharmacist in the metabolic syndrome has not yet been fully explored. Aim of the ... Read more >>

Int J Clin Pharm (International journal of clinical pharmacy)
[2020, :]

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Characteristics of drug-related problems among hospitalized ischemic stroke patients in China.

Qingqing Chen, Zhao Jin, Ping Zhang, Shusen Sun, Ling Li, Yun Liao,

Background Patients with ischemic stroke are often taking multiple medications and are at increased risk for drug-related problems (DRPs). However, the prevalence and nature of DRPs in these patients in China and the impact of pharmacist interventions to resolve DRPs in this population are unknown. Objective To investigate the prevalence ... Read more >>

Int J Clin Pharm (International journal of clinical pharmacy)
[2020, :]

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Duration of opioid use and association with socioeconomic status, daily dose and formulation: a two-decade population study in Queensland, Australia.

Adeleke D Adewumi, Joemer C Maravilla, Rosa Alati, Samantha A Hollingworth, Xuelei Hu, Bill Loveday, Jason P Connor,

Background There is an association between the duration of prescription opioids use and an increased risk of serious harm, often unintentional. Objective (1) Describe the trends in duration of prescription opioids dispensing and, (2) determine the risk of long-term use (≥4 months) based on patients' socioeconomic status, daily dose in ... Read more >>

Int J Clin Pharm (International journal of clinical pharmacy)
[2020, :]

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What predicts pharmacists' engagement with opioid-outcome screening? Secondary analysis from an implementation study in community pharmacy.

Suzanne Nielsen, Paul Sanfilippo, Louisa Picco, Raimondo Bruno, Michala Kowalski, Pene Wood, Sarah Larney,

Background Pharmacists have a key role to play in identifying and responding to emerging clinical problems with prescribed opioids. A pilot study in Australia examined the implementation of screening and brief intervention (Routine Opioid Outcome Monitoring [ROOM]) to identify and respond to opioid-related problems in community pharmacies. In this implementation study, the ... Read more >>

Int J Clin Pharm (International journal of clinical pharmacy)
[2020, :]

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Cost-effectiveness of atezolizumab plus chemotherapy for advanced non-small-cell lung cancer.

Shen Lin, Shaohong Luo, Lixian Zhong, Shubin Lai, Dayong Zeng, Xin Rao, Pinfang Huang, Xiuhua Weng,

Background Adding atezolizumab to carboplatin/nab-paclitaxel improved progression-free survival and overall survival in patients with advanced non-squamous non-small-cell lung cancer. However, estimating the economy of atezolizumab/carboplatin/nab-paclitaxel is urgent on account of the high cost of atezolizumab. Objective This study aimed to evaluate the cost-effectiveness of atezolizumab plus carboplatin/nab- paclitaxel for untreated ... Read more >>

Int J Clin Pharm (International Journal of Clinical Pharmacy)
[2020, :]

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The use of dietary supplements by patients in the pre-operative period in the Czech Republic.

Julie Zubrova, Jitka Pokladnikova, Jan Draessler,

Background The prevalence of dietary supplement use in the pre-operative period ranges from 4.8 to 80%. According to the Food and Drug Administration, some dietary supplements may show side effects before, during and after surgery. Objective The main aim of the study was to determine the prevalence of dietary supplement ... Read more >>

Int J Clin Pharm (International journal of clinical pharmacy)
[2020, :]

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Hematologic adverse effects induced by piperacillin-tazobactam: a systematic review of case reports.

Qingqing Wang, Zhongfang He, Xin'an Wu, Yuhui Wei, Jianlin Huang,

Background Piperacillin/tazobactam, a semisynthetic antibiotic, is widely used to treat polymicrobial infections. Its hematologic adverse reactions are rare and the severity can be mild to life-threatening. To our knowledge, there has not been a publication reviewing hematologic abnormalities attributable to piperacillin/tazobactam. Aim of the review To evaluate the characteristic, clinical ... Read more >>

Int J Clin Pharm (International journal of clinical pharmacy)
[2020, :]

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Provision of community pharmacy services during COVID-19 pandemic: a cross sectional study of community pharmacists' experiences with preventative measures and sources of information.

Kreshnik Hoti, Arianit Jakupi, Dardan Hetemi, Denis Raka, Jeffery Hughes, Shane Desselle,

Background An infectious disease caused by a novel coronavirus (later called COVID-19) reached pandemic levels in 2020 and community pharmacists were involved in responding to this pandemic, also in Kosovo. Objectives To explore the experiences of community pharmacists in relation to provision of community pharmacy services during COVID-19 pandemic. Setting ... Read more >>

Int J Clin Pharm (International journal of clinical pharmacy)
[2020, :]

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Evaluation of the medication reconciliation process and classification of discrepancies at hospital admission and discharge in Italy.

Mattia Dei Tos, Cristina Canova, Teresa Dalla Zuanna,

Background Medication errors at different transitions of care are common and potentially harmful. Medication reconciliation process should be evaluated to reduce the unintentional discrepancies. Objective This study aims to identify and classify unintentional medication discrepancies at hospital admission and discharge and associated risk factors. Setting Two general internal medicine and ... Read more >>

Int J Clin Pharm (International journal of clinical pharmacy)
[2020, :]

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A novel approach to medicines optimisation post-discharge from hospital: pharmacist-led medicines optimisation clinic.

Mohanad Odeh, Claire Scullin, Anita Hogg, Glenda Fleming, Michael G Scott, James C McElnay,

Background There is a major drive within healthcare to reduce patient readmissions, from patient care and cost perspectives. Pharmacist-led innovations have been demonstrated to enhance patient outcomes. Objective To assess the impact of a post-discharge, pharmacist-led medicines optimisation clinic on readmission parameters. Assessment of the economic, clinical and humanistic outcomes ... Read more >>

Int J Clin Pharm (International journal of clinical pharmacy)
[2020, :]

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Pharmacotherapy and inappropriate prescriptions in patients with psoriasis.

Luis Fernando Valladales-Restrepo, Jorge Enrique Machado-Alba,

Background Psoriasis is a chronic inflammatory and systemic disease that primarily affects the skin, nails, and joints. Some medications have been linked to worsening clinical manifestations of cutaneous psoriasis. Objective To identify pharmacological treatments and drugs related to worsening dermatological lesions in patients with psoriasis. Setting Patients diagnosed with psoriasis ... Read more >>

Int J Clin Pharm (International journal of clinical pharmacy)
[2020, :]

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Tigecycline-associated hypofibrinogenemia in a real-world setting.

David Campany-Herrero, Maria Larrosa-Garcia, Pilar Lalueza-Broto, Lucas Rivera-Sánchez, Juan Espinosa-Pereiro, Jaume Mestre-Torres, Carles Pigrau-Serrallach,

Background Tigecycline is a broad-spectrum antibiotic used to treat infections that do not respond to first-line treatments. High-doses and extended treatments are common; therefore, adverse events might be more frequent and severe than those observed in clinical trials. Several case-reports have referred hypofibrinogenemia in patients who received tigecycline. Objective To ... Read more >>

Int J Clin Pharm (International journal of clinical pharmacy)
[2020, :]

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Adherence to tyrosine kinase inhibitors among adult chronic myeloid leukemia patients in a Malaysia hospital.

P M Lee, C T Chang, Z M Yusoff,

Background Tyrosine kinase inhibitors have been demonstrated to improve the survival of patients with chronic myeloid leukaemia. However, medication adherence is vital for patients on chronic treatment. Objective The objective of the current study was to evaluate response to treatment, adherence by patients to tyrosine kinase inhibitors and factors associated ... Read more >>

Int J Clin Pharm (International journal of clinical pharmacy)
[2020, :]

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Self-reported clinical pharmacy service provision in Austria: an analysis of both the community and hospital pharmacy sector-a national study.

S Deibl, D Mueller, K Kirchdorfer, G Stemer, M Hoppel, A E Weidmann,

Background With expansion of more advanced clinical roles for pharmacists we need to be mindful that the extent to which clinical pharmacy services are implemented varies from one country to another. To date no comprehensive assessment of number and types of services provided by either community or hospital pharmacies in Austria ... Read more >>

Int J Clin Pharm (International journal of clinical pharmacy)
[2020, :]

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Prevalence of potential drug-drug interactions in outpatients of a general hospital in China: a retrospective investigation.

Weifang Ren, Yujuan Liu, Jun Zhang, Zhonghong Fang, Huan Fang, Yuan Gong, Xiaoqun Lv,

Background Potential drug-drug interactions are important factors resulting in adverse drug reactions or therapeutic failure. Therefore, potential drug-drug interactions need to be identified to prevent the related risk and improve drug safety. Objective This study was designed to determine the prevalence of potential drug-drug interactions and investigate the association of ... Read more >>

Int J Clin Pharm (International journal of clinical pharmacy)
[2020, :]

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Prevalence, associated factors and reasons for antibiotic self-medication among dwellers in Anuradhapura: a community-based study.

Devarajan Rathish, Nuwan Darshana Wickramasinghe,

Background Antimicrobial resistance is cited as one of the leading causes for the increased morbidity and mortality in infectious diseases globally. Antibiotic misuse can accelerate the advent and spread of resistant antimicrobial strains and antibiotic self-medication is one of the main practices of antibiotic misuse. Even though plethora of evidence ... Read more >>

Int J Clin Pharm (International journal of clinical pharmacy)
[2020, :]

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Impact of a pharmacist-administered deprescribing intervention on nursing home residents: a randomized controlled trial.

Cathy Balsom, Nicole Pittman, Renee King, Debbie Kelly,

Background Polypharmacy is prevalent among long-term care residents in Canada, with 48.4% receiving ten or more different medications and 40.7% chronically prescribed potentially inappropriate medications. Objective We implemented a pharmacist-administered deprescribing program in a long-term care facility to determine if the number of medications taken per resident could be reduced. SETTING:A long-term ... Read more >>

Int J Clin Pharm (International journal of clinical pharmacy)
[2020, :]

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Medication-related hospital admissions and readmissions in older patients: an overview of literature.

A E M J H Linkens, V Milosevic, P H M van der Kuy, V H Damen-Hendriks, C Mestres Gonzalvo, K P G M Hurkens,

Background The number of medication related hospital admissions and readmissions are increasing over the years due to the ageing population. Medication related hospital admissions and readmissions lead to decreased quality of life and high healthcare costs. Aim of the review To assess what is currently known about medication related hospital ... Read more >>

Int J Clin Pharm (International journal of clinical pharmacy)
[2020, :]

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Core competencies for Australian pharmacists when supplying prescribed opioids: a modified Delphi study.

Ella Maher, Suzanne Nielsen, Richard Summers, Pene Wood,

Background In the past decade, there has been an increase in prescription opioid related harms. These include dependence, non-fatal and fatal overdose. Pharmacists play a an important role in safe opioid supply. As most opioids are supplied through pharmacies, pharmacists are in a prime position to reduce harms associated with opioid ... Read more >>

Int J Clin Pharm (International journal of clinical pharmacy)
[2020, :]

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Knowledge, perceived barriers and facilitators of medication error reporting: a quantitative survey in Malaysian primary care clinics.

A Samsiah, Noordin Othman, Shazia Jamshed, Mohamed Azmi Hassali,

Background Medication errors are the most common types of medical errors that occur in health care organisations; however, these errors are largely underreported. Objective This study assessed knowledge on medication error reporting, perceived barriers to reporting medication errors, motivations for reporting medication errors and medication error reporting practices among various ... Read more >>

Int J Clin Pharm (International journal of clinical pharmacy)
[2020, :]

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Association of health literacy and cognition levels with severity of adverse drug reactions in cancer patients: a South Asian experience.

Vishal Gupta, Gangachannaiah Shivaprakash, Dipanjan Bhattacherjee, Karthik Udupa, Basavaraj Poojar, Ravi Sori, Shubhangi Mishra,

Background The occurrence of adverse drug reactions with chemotherapy among cancer patients is a well-documented phenomenon. However, the understanding of contributoring factors and their influence on the severity of adverse drug reactions is incomplete without the psychosocial factors affecting them. Objective The present study was done to understand if factors ... Read more >>

Int J Clin Pharm (International journal of clinical pharmacy)
[2020, :]

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Patient safety incidents involving transdermal opioids: data from the Danish Patient Safety Database.

A E Olesen, J N Henriksen, L P Nielsen, P Knudsen, B K Poulsen,

Background Transdermal opioids are widely used among elderly adults with chronic pain. However, transdermal patches may be involved in a significant proportion of opioid-related patient safety incidents, as the application process includes several subprocesses, each associated with an individual risk of error. Objective The aim was to obtain specific knowledge ... Read more >>

Int J Clin Pharm (International journal of clinical pharmacy)
[2020, :]

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Compliance to prescribing guidelines among public health care facilities in Namibia; findings and implications.

Qamar Niaz, Brian Godman, Stephen Campbell, Dan Kibuule,

Background The World Health Organization estimates that over 50% medicines are prescribed inappropriately and the main driver of antimicrobial resistance globally. There have only been a limited number of studies evaluating prescribing patterns against national standard treatment guidelines (STGs) in sub-Saharan African countries including Namibia. This is important given the ... Read more >>

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[2020, :]

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Co-trimoxazole induced hyperkalemia and potassium monitoring in hospitalized patients.

Milan M E A Plantaz, Bart A J Veldman, Anne C Esselink, Hanneke W H A Fleuren, Cornelis Kramers,

Background Co-trimoxazole is an antibiotic combination used for the treatment of Pneumocystis jirovecii pneumonia, amongst others. Co-trimoxazole is known to increase serum potassium. For this reason, Dutch guidelines advise serum potassium monitoring in high-risk patients. Objective This study aimed to determine average serum potassium rise after administration of intravenous co-trimoxazole ... Read more >>

Int J Clin Pharm (International journal of clinical pharmacy)
[2020, 42(3):965-971]

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The role of a Coronavirus disease 2019 pharmacist: an Australian perspective.

Jenny Nguy, Sarah A Hitchen, Adam L Hort, Cindy Huynh, Matthew D M Rawlins,

The coronavirus disease 2019 (COVID-19) pandemic has greatly impacted healthcare services around the world. Pharmacists are front-line healthcare professionals and integral members of the healthcare team. The deployment of a specialized 'COVID pharmacist' within our institution has demonstrated that the skills of the pharmacist can be adapted, expanded and utilized ... Read more >>

Int J Clin Pharm (International journal of clinical pharmacy)
[2020, :]

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