Gut (Gut)
[2020, 69(10):e7]
Cited: 0 times
Gut (Gut)
[2020, 69(10):e8]
Cited: 0 times
Savio George Barreto, Aida Habtezion, Anna Gukovskaya, Aurelia Lugea, Christie Jeon, Dhiraj Yadav, Peter Hegyi, Viktória Venglovecz, Robert Sutton, Stephen J Pandol,
Acute pancreatitis (AP), an acute inflammatory disorder of the exocrine pancreas, is one of the most common gastrointestinal diseases encountered in emergency departments with no specific treatments. Laboratory-based research has formed the cornerstone of endeavours to decipher the pathophysiology of AP, because of the limitations of such study in human ... Read more >>
Gut (Gut)
[2020, :]
Cited: 0 times
Gut (Gut)
[2020, 69(10):e6]
Cited: 0 times
John David Chetwood, Sanjivan Mudaliar, Dominic Staudenmann, Joo-Shik Shin, Ken Liu, Avik Majumdar, Arthur Kaffes, Simone Strasser, Geoffrey W McCaughan, Payal Saxena,
Gut (Gut)
[2020, :]
Cited: 0 times
Julien Pujo, Camille Petitfils, Pauline Le Faouder, Venessa Eeckhaut, Gaelle Payros, Sarah Maurel, Teresa Perez-Berezo, Matthias Van Hul, Frederick Barreau, Catherine Blanpied, Stephane Chavanas, Filip Van Immerseel, Justine Bertrand-Michel, Eric Oswald, Claude Knauf, Gilles Dietrich, Patrice D Cani, Nicolas Cenac,
OBJECTIVE:Data from clinical research suggest that certain probiotic bacterial strains have the potential to modulate colonic inflammation. Nonetheless, these data differ between studies due to the probiotic bacterial strains used and the poor knowledge of their mechanisms of action. DESIGN:By mass-spectrometry, we identified and quantified free long chain fatty acids ... Read more >>
Gut (Gut)
[2020, :]
Cited: 0 times
Christopher J Black, Orla Craig, David J Gracie, Alexander C Ford,
OBJECTIVES:Despite being proposed 4 years ago, there has been no independent validation study of the Rome IV criteria for IBS. We assessed their performance for the diagnosis of IBS in secondary care and compared them with the previous iteration, the Rome III criteria. DESIGN:We collected complete symptom data from consecutive ... Read more >>
Gut (Gut)
[2020, :]
Cited: 0 times
Alessandro Mantovani, Graziana Petracca, Giorgia Beatrice, Herbert Tilg, Christopher D Byrne, Giovanni Targher,
OBJECTIVE:Follow-up studies have shown that non-alcoholic fatty liver disease (NAFLD) is associated with an increased risk of incident diabetes, but currently, it is uncertain whether this risk changes with increasing severity of NAFLD. We performed a meta-analysis of relevant studies to quantify the magnitude of the association between NAFLD and ... Read more >>
Gut (Gut)
[2020, :]
Cited: 0 times
Kecheng Liu, Peng Peng, Fuqing Cai, Jiean Huang,
Gut (Gut)
[2020, :]
Cited: 0 times
Olga P Nyssen, Dimitry Bordin, Bojan Tepes, Ángeles Pérez-Aisa, Dino Vaira, Maria Caldas, Luis Bujanda, Manuel Castro-Fernandez, Frode Lerang, Marcis Leja, Luís Rodrigo, Theodore Rokkas, Limas Kupcinskas, Jorge Pérez-Lasala, Laimas Jonaitis, Oleg Shvets, Antonio Gasbarrini, Halis Simsek, Anthony T R Axon, György Buzás, Jose Carlos Machado, Yaron Niv, Lyudmila Boyanova, Adrian Goldis, Vincent Lamy, Ante Tonkic, Krzysztof Przytulski, Christoph Beglinger, Marino Venerito, Peter Bytzer, Lisette Capelle, Tomica Milosavljević, Vladimir Milivojevic, Lea Veijola, Javier Molina-Infante, Liudmila Vologzhanina, Galina Fadeenko, Ines Ariño, Giulia Fiorini, Ana Garre, Jesús Garrido, Cristina F Pérez, Ignasi Puig, Frederic Heluwaert, Francis Megraud, Colm O'Morain, Javier P Gisbert, ,
OBJECTIVE:The best approach for Helicobacter pylori management remains unclear. An audit process is essential to ensure clinical practice is aligned with best standards of care. DESIGN:International multicentre prospective non-interventional registry starting in 2013 aimed to evaluate the decisions and outcomes in H. pylori management by European gastroenterologists. Patients were registered ... Read more >>
Gut (Gut)
[2020, :]
Cited: 0 times
David Y Graham, Hashem B El-Serag,
Gut (Gut)
[2020, :]
Cited: 0 times
The gastrointestinal tract is often considered as a key organ involved in the digestion of food and providing nutrients to the body for proper maintenance. However, this system is composed of organs that are extremely complex. Among the different parts, the intestine is viewed as an incredible surface of contact ... Read more >>
Gut (Gut)
[2020, :]
Cited: 0 times
Aitor Esparza-Baquer, Ibone Labiano, Omar Sharif, Aloña Agirre-Lizaso, Fiona Oakley, Pedro M Rodrigues, Ekaterina Zhuravleva, Colm J O'Rourke, Elizabeth Hijona, Raul Jimenez-Agüero, Ioana Riaño, Ana Landa, Adelaida La Casta, Marco Y W Zaki, Patricia Munoz-Garrido, Mikel Azkargorta, Felix Elortza, Andrea Vogel, Gernot Schabbauer, Patricia Aspichueta, Jesper B Andersen, Sylvia Knapp, Derek A Mann, Luis Bujanda, Jesus Maria Banales, Maria Jesus Perugorria,
OBJECTIVE:Hepatocellular carcinoma (HCC) is a prevalent and aggressive cancer usually arising on a background of chronic liver injury involving inflammatory and hepatic regenerative processes. The triggering receptor expressed on myeloid cells 2 (TREM-2) is predominantly expressed in hepatic non-parenchymal cells and inhibits Toll-like receptor signalling, protecting the liver from various ... Read more >>
Gut (Gut)
[2020, :]
Cited: 0 times
Robert C Grant, Robert Denroche, Gun Ho Jang, Klaudia M Nowak, Amy Zhang, Ayelet Borgida, Spring Holter, James T Topham, Julie Wilson, Anna Dodd, Raymond Jang, Rebecca Prince, Joanna M Karasinska, David F Schaeffer, Yifan Wang, George Zogopoulos, Scott Berry, Diane Simeone, Daniel J Renouf, Faiyaz Notta, Grainne O'Kane, Jennifer Knox, Sandra Fischer, Steven Gallinger,
OBJECTIVE:To describe the clinical, pathological and genomic characteristics of pancreatic cancer with DNA mismatch repair deficiency (MMRD) and proficiency (MMRP). DESIGN:We identified patients with MMRD and MMRP pancreatic cancer in a clinical cohort (N=1213, 519 with genetic testing, 53 with immunohistochemistry (IHC)) and a genomic cohort (N=288 with whole-genome sequencing ... Read more >>
Gut (Gut)
[2020, :]
Cited: 0 times
Matthew D Rutter, Rachel Evans, Zoe Hoare, Christian Von Wagner, Jill Deane, Shiran Esmaily, Tony Larkin, Rhiannon Edwards, Seow Tien Yeo, Llinos Haf Spencer, Emily Holmes, Brian P Saunders, Colin J Rees, Zacharias P Tsiamoulos, Iosif Beintaris, ,
OBJECTIVES:The English Bowel Cancer Screening Programme invites 55 year olds for a sigmoidoscopy (Bowel Scope Screening (BSS)), aiming to resect premalignant polyps, thus reducing cancer incidence. A national patient survey indicated higher procedural pain than anticipated, potentially impacting on screening compliance and effectiveness. We aimed to assess whether water-assisted sigmoidoscopy (WAS), ... Read more >>
Gut (Gut)
[2020, :]
Cited: 0 times
Bu'Hussain Hayee, , James East, Colin J Rees, Ian Penman,
Gut (Gut)
[2020, :]
Cited: 0 times
Bram Verstockt, Liesbeth Boets, João Sabino, Séverine Vermeire, Marc Ferrante,
Gut (Gut)
[2020, :]
Cited: 0 times
Johann von Felden, Teresa Garcia-Lezana, Kornelius Schulze, Bojan Losic, Augusto Villanueva,
With increasing knowledge on molecular tumour information, precision oncology has revolutionised the medical field over the past years. Liquid biopsy entails the analysis of circulating tumour components, such as circulating tumour DNA, tumour cells or tumour-derived extracellular vesicles, and has thus come as a handy tool for personalised medicine in ... Read more >>
Gut (Gut)
[2020, :]
Cited: 0 times
Qiang Feng, Xiang Lan, Xiaoli Ji, Meihui Li, Shili Liu, Jianghui Xiong, Yanbo Yu, Zhipeng Liu, Zi Xu, Li He, Ying Chen, Haisheng Dong, Pu Chen, Bin Chen, Kunlun He, Yinghui Li,
Gut (Gut)
[2020, :]
Cited: 0 times
Johann Gout, Lukas Perkhofer, Mareen Morawe, Frank Arnold, Michaela Ihle, Stephanie Biber, Sebastian Lange, Elodie Roger, Johann M Kraus, Katja Stifter, Stephan A Hahn, Andrea Zamperone, Thomas Engleitner, Martin Müller, Karolin Walter, Eva Rodriguez-Aznar, Bruno Sainz, Patrick C Hermann, Elisabeth Hessmann, Sebastian Müller, Ninel Azoitei, André Lechel, Stefan Liebau, Martin Wagner, Diane M Simeone, Hans A Kestler, Thomas Seufferlein, Lisa Wiesmüller, Roland Rad, Pierre-Olivier Frappart, Alexander Kleger,
OBJECTIVE:ATM serine/threonine kinase (ATM) is the most frequently mutated DNA damage response gene, involved in homologous recombination (HR), in pancreatic ductal adenocarcinoma (PDAC). DESIGN:Combinational synergy screening was performed to endeavour a genotype-tailored targeted therapy. RESULTS:Synergy was found on inhibition of PARP, ATR and DNA-PKcs (PAD) leading to synthetic lethality in ... Read more >>
Gut (Gut)
[2020, :]
Cited: 0 times
Richard Hansen, Susanna Meade, R Mark Beattie, Marcus Kh Auth, Nick Croft, Philip Davies, David Devadason, Conor Doherty, Jenny Epstein, Lucy Howarth, Fevronia Kiparissi, Rafeeq Muhammed, Vinay Shivamurthy, Christine Spray, Michael P Stanton, Franco Torrente, Arun Urs, David Wilson, Peter M Irving, Mark Samaan, Jochen Kammermeier,
OBJECTIVE:Paediatric acute severe colitis (ASC) management during the novel SARS-CoV-2/COVID-19 pandemic is challenging due to reliance on immunosuppression and the potential for surgery. We aimed to provide COVID-19-specific guidance using the European Crohn's and Colitis Organisation/European Society for Paediatric Gastroenterology, Hepatology and Nutrition guidelines for comparison. DESIGN:We convened a RAND ... Read more >>
Gut (Gut)
[2020, :]
Cited: 0 times
Ji Young Bang, Robert Hawes, Shyam Varadarajulu,
OBJECTIVE:Single-use duodenoscopes have been recently developed to eliminate risk of infection transmission from contaminated reusable duodenoscopes. We compared performances of single-use and reusable duodenoscopes in patients undergoing endoscopic retrograde cholangiopancreatography (ERCP). DESIGN:Patients with native papilla requiring ERCP were randomised to single-use or reusable duodenoscope. Primary outcome was comparing number of ... Read more >>
Gut (Gut)
[2020, :]
Cited: 0 times
Chun-Ying Wu, Hsiu J Ho, Chen-Yi Wu, Yi-Ju Chen, Teng-Tu Lee, Yao-Chun Hsu, Jaw-Town Lin,
Gut (Gut)
[2020, :]
Cited: 0 times
Katherine Dixon, Janine Senz, Pardeep Kaurah, David G Huntsman, Kasmintan A Schrader,
Gut (Gut)
[2020, :]
Cited: 0 times
Manasi Agrawal, Giulia Corn, Sarita Shrestha, Nete Munk Nielsen, Morten Frisch, Jean-Frederic Colombel, Tine Jess,
OBJECTIVE:Our objective was to estimate the relative risk of IBD among first-generation and second-generation immigrants in Denmark compared with native Danes. DESIGN:Using national registries, we established a cohort of Danish residents between 1977 and 2018. Cohort members with known country of birth were followed for Crohn's disease (CD) and ulcerative ... Read more >>
Gut (Gut)
[2020, :]
Cited: 0 times