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Considerations for Neuromorphic Supercomputing in Semiconducting and Superconducting Optoelectronic Hardware.

Bryce A Primavera, Jeffrey M Shainline,

Any large-scale spiking neuromorphic system striving for complexity at the level of the human brain and beyond will need to be co-optimized for communication and computation. Such reasoning leads to the proposal for optoelectronic neuromorphic platforms that leverage the complementary properties of optics and electronics. Starting from the conjecture that ... Read more >>

Front Neurosci (Frontiers in neuroscience)
[2021, 15:732368]

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Age-Related Changes in the Cochlea and Vestibule: Shared Patterns and Processes.

Vasiliki Paplou, Nick M A Schubert, Sonja J Pyott,

Both age-related hearing loss (ARHL) and age-related loss in vestibular function (ARVL) are prevalent conditions with deleterious consequences on the health and quality of life. Age-related changes in the inner ear are key contributors to both conditions. The auditory and vestibular systems rely on a shared sensory organ - the ... Read more >>

Front Neurosci (Frontiers in neuroscience)
[2021, 15:680856]

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More Negative FRN From Stopping Searches Too Late Than Too Early: An ERP Study.

Mei Gao, Xiaolan Yang, Linanzi Zhang, Qingguo Ma,

It is widely known that the feedback from a decision outcome may evoke emotions like regret, which results from a comparison between the gain the decision-maker has made and the gain he/she might make. Less is known about how search behavior is linked to feedback in a sequential search task ... Read more >>

Front Neurosci (Frontiers in neuroscience)
[2021, 15:705000]

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Editorial: Roles of Sleep Disruption and Circadian Rhythm Alterations on Neurodegeneration and Alzheimer's Disease.

Marilyn J Duncan, Sigrid C Veasey, Phyllis Zee,

Front Neurosci (Frontiers in neuroscience)
[2021, 15:737895]

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rTMS Induces Brain Functional and Structural Alternations in Schizophrenia Patient With Auditory Verbal Hallucination.

Yuanjun Xie, Muzhen Guan, Zhongheng Wang, Zhujing Ma, Huaning Wang, Peng Fang, Hong Yin,

<h4>Background</h4>Low-frequency transcranial magnetic stimulation (rTMS) over the left temporoparietal cortex reduces the auditory verbal hallucination (AVH) in schizophrenia. However, the underlying neural basis of the rTMS treatment effect for schizophrenia remains not well understood. This study investigates the rTMS induced brain functional and structural alternations and their associations with clinical ... Read more >>

Front Neurosci (Frontiers in neuroscience)
[2021, 15:722894]

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Validation and Reliability of a Novel Vagus Nerve Neurodynamic Test and Its Effects on Heart Rate in Healthy Subjects: Little Differences Between Sexes.

Giacomo Carta, Agnese Seregni, Andrea Casamassima, Manuela Galli, Stefano Geuna, Pasquale Pagliaro, Matteo Zago,

<h4>Background</h4>The vagus nerve (VN), also called the pneumogastric nerve, connects the brainstem to organs contained in the chest and abdomen. Physiologically, VN stimulation can rapidly affect cardiac activity and heart rate (HR). VN neuropathy can increase the risk of arrhythmias and sudden death. Therefore, a selective test of VN function ... Read more >>

Front Neurosci (Frontiers in neuroscience)
[2021, 15:698470]

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Update on the Relationship Between Depression and Neuroendocrine Metabolism.

Wenxin Qiu, Xiaodan Cai, Chenhui Zheng, Shumin Qiu, Hanyang Ke, Yinqiong Huang,

Through the past decade of research, the correlation between depression and metabolic diseases has been noticed. More and more studies have confirmed that depression is comorbid with a variety of metabolic diseases, such as obesity, diabetes, metabolic syndrome and so on. Studies showed that the underlying mechanisms of both depression ... Read more >>

Front Neurosci (Frontiers in neuroscience)
[2021, 15:728810]

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A Contrast Augmentation Approach to Improve Multi-Scanner Generalization in MRI.

Maria Ines Meyer, Ezequiel de la Rosa, Nuno Pedrosa de Barros, Roberto Paolella, Koen Van Leemput, Diana M Sima,

Most data-driven methods are very susceptible to data variability. This problem is particularly apparent when applying Deep Learning (DL) to brain Magnetic Resonance Imaging (MRI), where intensities and contrasts vary due to acquisition protocol, scanner- and center-specific factors. Most publicly available brain MRI datasets originate from the same center and ... Read more >>

Front Neurosci (Frontiers in neuroscience)
[2021, 15:708196]

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Retinal Diseases and Parkinson Disease: A Population-Based Study.

Po-Chih Chen, Chen-Chih Chung, Yun-Yung Cheng, Wan-Ting Chen, Chien-Tai Hong, Lung Chan, Li-Nien Chien,

<h4>Introduction</h4>Patients with Parkinson disease (PD) tend to have ophthalmic symptoms. Retinal diseases are associated with central nervous system diseases, especially neurodegenerative diseases. Here, we investigated the association of retinal diseases with PD, especially the temporal relationship before and after PD diagnosis.<h4>Methods</h4>Data were obtained from the National Health Insurance Research Database ... Read more >>

Front Neurosci (Frontiers in neuroscience)
[2021, 15:679092]

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Neurofilament Light Chain and Intermediate HTT Alleles as Combined Biomarkers in Italian ALS Patients.

Assunta Ingannato, Silvia Bagnoli, Salvatore Mazzeo, Valentina Bessi, Sabrina Matà, Monica Del Mastio, Gemma Lombardi, Camilla Ferrari, Sandro Sorbi, Benedetta Nacmias,

<h4>Objective</h4>To study the possible implication of the two biomarkers, intermediate alleles (IAs) of the Huntingtin (HTT) gene and neurofilament light chain (NfL) levels in plasma, in amyotrophic lateral sclerosis (ALS) patients.<h4>Methods</h4>We analyzed IAs in a cohort of 106 Italian ALS patients and measured the plasma NfL levels in 20% of ... Read more >>

Front Neurosci (Frontiers in neuroscience)
[2021, 15:695049]

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Repeated Parental Singing During Kangaroo Care Improved Neural Processing of Speech Sound Changes in Preterm Infants at Term Age.

Kaisamari Kostilainen, Eino Partanen, Kaija Mikkola, Valtteri Wikström, Satu Pakarinen, Vineta Fellman, Minna Huotilainen,

Preterm birth carries a risk for adverse neurodevelopment. Cognitive dysfunctions, such as language disorders may manifest as atypical sound discrimination already in early infancy. As infant-directed singing has been shown to enhance language acquisition in infants, we examined whether parental singing during skin-to-skin care (kangaroo care) improves speech sound discrimination ... Read more >>

Front Neurosci (Frontiers in neuroscience)
[2021, 15:686027]

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Relationship Between Epilepsy and Dreaming: Current Knowledge, Hypotheses, and Perspectives.

Aurélien de la Chapelle, Birgit Frauscher, Amandine Valomon, Perrine Marie Ruby, Laure Peter-Derex,

The interactions between epilepsy and sleep are numerous and the impact of epilepsy on cognition is well documented. Epilepsy is therefore likely to influence dreaming as one sleep-related cognitive activity. The frequency of dream recall is indeed decreased in patients with epilepsy, especially in those with primary generalized seizures. The ... Read more >>

Front Neurosci (Frontiers in neuroscience)
[2021, 15:717078]

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Olivocochlear Changes Associated With Aging Predominantly Affect the Medial Olivocochlear System.

Sergio Vicencio-Jimenez, Madison M Weinberg, Giuliana Bucci-Mansilla, Amanda M Lauer,

Age-related hearing loss (ARHL) is a public health problem that has been associated with negative health outcomes ranging from increased frailty to an elevated risk of developing dementia. Significant gaps remain in our knowledge of the underlying central neural mechanisms, especially those related to the efferent auditory pathways. Thus, the ... Read more >>

Front Neurosci (Frontiers in neuroscience)
[2021, 15:704805]

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The Relationships Among Transverse Sinus Stenosis Measured by CT Venography, Venous Trans-stenotic Pressure Gradient and Intracranial Pressure in Patients With Unilateral Venous Pulsatile Tinnitus.

Xiaoyu Qiu, Pengfei Zhao, Xiaoshuai Li, Heyu Ding, Han Lv, Rong Zeng, Guopeng Wang, Long Jin, Zhenghan Yang, Shusheng Gong, Zhenchang Wang,

<h4>Objectives</h4>To assess a non-invasive means of predicting a venous <i>trans</i>-stenotic pressure gradient (TPG) and intracranial pressure (ICP) as opposed to invasive examinations in unilateral venous pulsatile tinnitus (PT) patients.<h4>Methods</h4>Thirty patients with unilateral venous PT who presented symptomatic-sided transverse sinus stenosis (TSS) on computed tomography venography (CTV), ipsilateral TPG measured by ... Read more >>

Front Neurosci (Frontiers in neuroscience)
[2021, 15:694731]

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Dysregulation of Principal Circulating miRNAs in Non-human Primates Following Ischemic Stroke.

Jian Chen, Haiping Zhao, Yuyou Huang, Yuqian Li, Junfen Fan, Rongliang Wang, Ziping Han, Zhenhong Yang, Longfei Wu, Di Wu, Yumin Luo, Xunming Ji,

Despite the recent interest in plasma microRNA (miRNA) biomarkers in acute ischemic stroke patients, there is limited knowledge about the miRNAs directly related to stroke itself due to the multiple complications in patients, which has hindered the research progress of biomarkers and therapeutic targets of ischemic stroke. Therefore, in this ... Read more >>

Front Neurosci (Frontiers in neuroscience)
[2021, 15:738576]

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A Novel Two-Stage Refine Filtering Method for EEG-Based Motor Imagery Classification.

Yuxin Yan, Haifeng Zhou, Lixin Huang, Xiao Cheng, Shaolong Kuang,

Cerebral stroke is a common disease across the world, and it is a promising method to recognize the intention of stroke patients with the help of brain-computer interface (BCI). In the field of motor imagery (MI) classification, appropriate filtering is vital for feature extracting of electroencephalogram (EEG) signals and consequently ... Read more >>

Front Neurosci (Frontiers in neuroscience)
[2021, 15:657540]

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Early Life Adversity and Polygenic Risk for High Fasting Insulin Are Associated With Childhood Impulsivity.

Aashita Batra, Lawrence M Chen, Zihan Wang, Carine Parent, Irina Pokhvisneva, Sachin Patel, Robert D Levitan, Michael J Meaney, Patricia Pelufo Silveira,

While the co-morbidity between metabolic and psychiatric behaviors is well-established, the mechanisms are poorly understood, and exposure to early life adversity (ELA) is a common developmental risk factor. ELA is associated with altered insulin sensitivity and poor behavioral inhibition throughout life, which seems to contribute to the development of metabolic ... Read more >>

Front Neurosci (Frontiers in neuroscience)
[2021, 15:704785]

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Manual Gestures Modulate Early Neural Responses in Loudness Perception.

Jiaqiu Sun, Ziqing Wang, Xing Tian,

How different sensory modalities interact to shape perception is a fundamental question in cognitive neuroscience. Previous studies in audiovisual interaction have focused on abstract levels such as categorical representation (e.g., McGurk effect). It is unclear whether the cross-modal modulation can extend to low-level perceptual attributes. This study used motional manual ... Read more >>

Front Neurosci (Frontiers in neuroscience)
[2021, 15:634967]

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Vasopressin but Not Oxytocin Responds to Birth Stress in Infants.

Sara Fill Malfertheiner, Evelyn Bataiosu-Zimmer, Holger Michel, Sotirios Fouzas, Luca Bernasconi, Christoph Bührer, Sven Wellmann,

<h4>Context</h4>Birth triggers a large fetal neuroendocrine response, which is more pronounced in infants born vaginally than in those born by elective cesarean section (ECS). The two related peptides arginine vasopressin (AVP) and oxytocin (OT) play an essential role in peripheral and central stress adaptation and have a shared receptor mediating ... Read more >>

Front Neurosci (Frontiers in neuroscience)
[2021, 15:718056]

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Suppression, Maintenance, and Surprise: Neuronal Correlates of Predictive Processing Specialization for Musical Rhythm.

Ulvhild Færøvik, Karsten Specht, Kjetil Vikene,

Auditory repetition suppression and omission activation are opposite neural phenomena and manifestations of principles of predictive processing. Repetition suppression describes the temporal decrease in neural activity when a stimulus is constant or repeated in an expected temporal fashion; omission activity is the transient increase in neural activity when a stimulus ... Read more >>

Front Neurosci (Frontiers in neuroscience)
[2021, 15:674050]

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Investigating Managers' Fine-Grained Evaluation Processes in Organizations: Exploring Two Dual-Process Perspectives.

Haoye Sun, Willem J M I Verbeke, Frank Belschak, Jan van Strien, Lei Wang,

The dual-process theory is a significant theory in both organizational theory and social psychology and two conjectures about this theory are considered in this manuscript; the default-interventionist vs. parallel-competitive account. Our research goal is to empirically investigate these two views. In concrete terms, by using event-related potentials (ERPs), we seek ... Read more >>

Front Neurosci (Frontiers in neuroscience)
[2021, 15:649941]

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Can Haptic Stimulation Enhance Music Perception in Hearing-Impaired Listeners?

Mark D Fletcher,

Cochlear implants (CIs) have been remarkably successful at restoring hearing in severely-to-profoundly hearing-impaired individuals. However, users often struggle to deconstruct complex auditory scenes with multiple simultaneous sounds, which can result in reduced music enjoyment and impaired speech understanding in background noise. Hearing aid users often have similar issues, though these ... Read more >>

Front Neurosci (Frontiers in neuroscience)
[2021, 15:723877]

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The Emerging Role of Neural Cell-Derived Exosomes in Intercellular Communication in Health and Neurodegenerative Diseases.

Luyao Huo, Xinzhe Du, Xinrong Li, Sha Liu, Yong Xu,

Intercellular communication in the central nervous system (CNS) is essential for brain growth, development, and homeostasis maintenance and, when dysfunctional, is involved in the occurrence and development of neurodegenerative diseases. Increasing evidence indicates that extracellular vesicles, especially exosomes, are critical mediators of intercellular signal transduction. Under physiological and pathological conditions, ... Read more >>

Front Neurosci (Frontiers in neuroscience)
[2021, 15:738442]

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Aberrant Intraregional Brain Activity and Functional Connectivity in Patients With Diarrhea-Predominant Irritable Bowel Syndrome.

Xiao-Fei Chen, Yun Guo, Xing-Qi Lu, Le Qi, Kuang-Hui Xu, Yong Chen, Guo-Xiong Li, Jian-Ping Ding, Jie Li,

<h4>Background and purpose</h4>The appearance and aggravation of diarrhea-predominant irritable bowel syndrome (IBS-D) have proven to be closely related to psychosocial factors. We aimed to measure altered spontaneous brain activity and functional connectivity (FC) in patients with IBS-D using resting-state functional magnetic resonance imaging (RS-fMRI) and to analyze the relationship between ... Read more >>

Front Neurosci (Frontiers in neuroscience)
[2021, 15:721822]

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Curcumin Exerts Antinociceptive Effects in Cancer-Induced Bone Pain via an Endogenous Opioid Mechanism.

Guanghai Zhao, Yongqiang Shi, Chaoyang Gong, Taicong Liu, Wei Nan, Lin Ma, Zuolong Wu, Chaoming Da, Kaisheng Zhou, Haihong Zhang,

Cancer pain is one of the main complications in advanced cancer patients, and its management is still challenging. Therefore, there is an urgent need to develop novel pharmacotherapy for cancer pain. Several natural products have attracted the interest of researchers. In previous studies, curcumin has proved to exhibit antitumor, antiviral, ... Read more >>

Front Neurosci (Frontiers in neuroscience)
[2021, 15:696861]

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