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Journal Eur. J. Clin. Microbiol. Infect. Dis.

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First report of meningococcal ciprofloxacin resistance in Greece due to invasive isolates of the sequence type ST-3129.

Georgina Tzanakaki, Theano Georgakopoulou, Athanasia Xirogianni, Anastasia Papandreou, Ala-Eddine Deghmane, Ioanna Magaziotou, Muhamed-Kheir Taha,

A local outbreak caused by Neisseria meningitidis occurred in the migration camp in the Greek island of Lesbos during January-February 2020 (4 of 5 cases). In total, 5 samples positive for N. meningitidis were further investigated for sero-/genogroup, PorA, and WGS analysis. MenB was found among 3 cases, while in ... Read more >>

Eur. J. Clin. Microbiol. Infect. Dis. (European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology)
[2020, :]

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Complement levels in patients with bloodstream infection due to Staphylococcus aureus or Gram-negative bacteria.

Emily M Eichenberger, Michael Dagher, Felicia Ruffin, Lawrence Park, Lisa Hersh, Sumathi Sivapalasingam, Vance G Fowler, Brinda C Prasad,

The complement system is a vital component of the innate immune system, though its role in bacteremia is poorly understood. We present complement levels in Staphylococcus aureus bacteremia (SAB) and Gram-negative bacteremia (GNB) and describe observed associations of complement levels with clinical outcomes. Complement and cytokine levels were measured in ... Read more >>

Eur. J. Clin. Microbiol. Infect. Dis. (European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology)
[2020, :]

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Decreased duration of intravenous cephalosporins in intensive care unit patients with selective digestive decontamination: a retrospective before-and-after study.

Calypso Mathieu, Roberta Abbate, Zoe Meresse, Emmanuelle Hammad, Gary Duclos, François Antonini, Nadim Cassir, Jeroen Schouten, Laurent Zieleskiewicz, Marc Leone,

Selective digestive decontamination (SDD) reduces the rate of infection and improves the outcomes of patients admitted to an intensive care unit (ICU). A risk associated with its use is the development of multi-drug-resistant organisms. We hypothesized that a 1-day reduction in systemic antimicrobial exposure in the SDD regimen would not ... Read more >>

Eur. J. Clin. Microbiol. Infect. Dis. (European Journal of Clinical Microbiology & Infectious Diseases)
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Decreased duration of intravenous cephalosporins in intensive care unit patients with selective digestive decontamination: a retrospective before-and-after study.

Calypso Mathieu, Roberta Abbate, Zoe Meresse, Emmanuelle Hammad, Gary Duclos, François Antonini, Nadim Cassir, Jeroen Schouten, Laurent Zieleskiewicz, Marc Leone,

Selective digestive decontamination (SDD) reduces the rate of infection and improves the outcomes of patients admitted to an intensive care unit (ICU). A risk associated with its use is the development of multi-drug-resistant organisms. We hypothesized that a 1-day reduction in systemic antimicrobial exposure in the SDD regimen would not ... Read more >>

Eur. J. Clin. Microbiol. Infect. Dis. (European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology)
[2020, :]

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Serotype distribution of Streptococcus pneumoniae among healthy carriers and clinical patients: a systematic review from Iran.

Maryam Alizadeh Chamkhaleh, Abdoulreza Esteghamati, Shirin Sayyahfar, Alireza Gandomi-Mohammadabadi, Javad Balasi, Hossein Abdiae, Yousef Moradi, Maziar Moradi-Lakeh,

Streptococcus pneumoniae is associated with high morbidity and mortality in the world. Commercially licensed and available pneumococcal conjugate vaccines (PCVs) contain 10 (PCV10) and 13 (PCV13) pneumococcal serotypes. The most common serotypes of S. pneumoniae causing clinical diseases and carriers of S. pneumoniae in Iran are not yet known. Reviewing ... Read more >>

Eur. J. Clin. Microbiol. Infect. Dis. (European Journal of Clinical Microbiology & Infectious Diseases)
[2020, :]

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Hypervitaminosis A is associated with immunological non-response in HIV-1-infected adults: a case-control study.

Hugues Melliez, Michel Prost, Hélène Behal, Nathalie Neveux, Jean-François Benoist, Isabelle Kim, Sylvie Mazzella, Vincent Derdour, Evelyne Sauser, Olivier Robineau, Eric Senneville, Luc Cynober, Raphaël Biekre, David Seguy,

For people living with HIV, determinants of immunological non-response (INR) to combined antiretroviral therapy (cART) have not been fully elucidated. In a case-control study, we evaluated the influence of the nutritional and antioxidant status in HIV-1 adults whose cART was initiated between January 2001 and December 2013. Cases had persistent ... Read more >>

Eur. J. Clin. Microbiol. Infect. Dis. (European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology)
[2020, :]

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Characteristics of laboratory indexes in COVID-19 patients with non-severe symptoms in Hefei City, China: diagnostic value in organ injuries.

Tao Li, Lianzi Wang, Huihui Wang, Yufeng Gao, Xianwei Hu, Xuemei Li, Shubing Zhang, Yuanhong Xu, Wei Wei,

This study compared the laboratory indexes in 40 non-severe COVID-19 patients with those in 57 healthy controls. In the peripheral blood system of non-severe symptom COVID-19 patients, lymphocytes, eosinophils, basophils, total procollagen type 1 amino-terminal propeptide, osteocalcin N-terminal, thyroid-stimulating hormone, growth hormone, and insulin-like growth factor-binding protein 3 significantly decreased, ... Read more >>

Eur. J. Clin. Microbiol. Infect. Dis. (European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology)
[2020, :]

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Population differentiation, antifungal susceptibility, and host range of Trichophyton mentagrophytes isolates causing recalcitrant infections in humans and animals.

Sebastian Gnat, Dominik Łagowski, Aneta Nowakiewicz, Marcelina Osińska, Łukasz Kopiński,

The major problems in determining the causative factors of the high prevalence of dermatophytoses include the lack of a well-standardized antifungal susceptibility testing method, the low consistency of in vitro and clinical minimal inhibitory concentration values, the high genomic diversity of the population, and the unclear mechanism of pathogenicity. These ... Read more >>

Eur. J. Clin. Microbiol. Infect. Dis. (European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology)
[2020, :]

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Urinary tract infection and antibiotic use around ureteral stent insertion for urolithiasis.

Bérénice Souhail, Patrick Charlot, Gilles Deroudilhe, Yves Coblentz, Gregory Pierquet, Pierre Gimel, Nathalie Challut, Thierry Levent, Stéphane Cusumano, Véronique Dautezac, Pierre-Marie Roger,

Urolithiasis is the main indication for a ureteral JJ stent. Our aim was to determine the incidence of urinary tract infections (UTIs) after a JJ stent for urolithiasis, with an emphasis on antibiotic use. Prospective, multicenter, cohort study over a 4-month period including all of the patients with urolithiasis requiring ... Read more >>

Eur. J. Clin. Microbiol. Infect. Dis. (European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology)
[2020, :]

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Influenza and respiratory syncytial virus infections in the oldest-old continent.

Matteo Boattini, André Almeida, Eirini Christaki, Lourenço Cruz, Diogo Antão, Maria Inês Moreira, Gabriele Bianco, Marco Iannaccone, Georgios Tsiolakkis, Elina Khattab, Diamanto Kasapi, Lorena Charrier, Valentina Tosatto, Torcato Moreira Marques, Rossana Cavallo, Cristina Costa,

SARS-CoV-2 dramatically revealed the sudden impact of respiratory viruses in our lives. Influenza and respiratory syncytial virus (RSV) infections are associated with high rates of morbidity, mortality, and an important burden on healthcare systems worldwide, especially in elderly patients. The aim of this study was to identify severity predictors in ... Read more >>

Eur. J. Clin. Microbiol. Infect. Dis. (European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology)
[2020, :]

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Multicenter evaluation of the RAPIDEC® CARBA NP assay for the detection of carbapenemase production in clinical isolates of Enterobacterales and Pseudomonas aeruginosa.

Allison R McMullen, Meghan A Wallace, Vincent LaBombardi, Janet Hindler, Shelley Campeau, Romney Humphries, Gary W Procop, Sandra S Richter, Mark G Wise, Carey-Ann D Burnham,

Carbapenem-resistant Gram-negative bacilli are a major public health problem. Accurate and rapid detection of carbapenemase-producing organisms can facilitate appropriate infection prevention measures. The objective was to evaluate the performance of the RAPIDEC® CARBA NP assay (RAPIDEC), a screening assay that utilizes a pH indicator to detect carbapenem hydrolysis within 2 h. ... Read more >>

Eur. J. Clin. Microbiol. Infect. Dis. (European Journal of Clinical Microbiology & Infectious Diseases)
[2020, :]

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Antibiotic modification versus withhold in febrile patients without evidence of bacterial infection, unresponsive to initial empiric regimen: a multicentre retrospective study conducted in Israel.

Hadar Mudrik-Zohar, Ran Nissan, Gideon Y Stein, Abd El-Haleem Natour, Danny Alon,

Prescribing antibiotics for febrile patients without proof of bacterial infection contributes to antimicrobial resistance. Lack of clinical response in these patients often leads to antibiotic escalation, although data supporting this strategy are scarce. This study compared outcomes of modifying, withholding, or continuing the same antibiotic regimen for such patients. Febrile ... Read more >>

Eur. J. Clin. Microbiol. Infect. Dis. (European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology)
[2020, :]

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Real-time PCR-based quantitation of viable Mycobacterium leprae strain from clinical samples and environmental sources and its genotype in multi-case leprosy families of India.

Vikram Singh, Ravindra P Turankar, Anjana Goel,

The potential role of environmental M. leprae in the transmission of leprosy remains unknown. We investigated role of environment as a possible source of viable M. leprae responsible for transmission of leprosy. The samples were collected from 10 multi-case leprosy families comprising, slit skin smear (SSS) from 9 multibacillary (MB), ... Read more >>

Eur. J. Clin. Microbiol. Infect. Dis. (European Journal of Clinical Microbiology & Infectious Diseases)
[2020, :]

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Human infections caused by Staphylococcus argenteus in Germany: genetic characterisation and clinical implications of novel species designation.

Farah Alhussein, Judith Fürstenberg, Rosmarie Gaupp, Janina Eisenbeis, Katharina Last, Sören L Becker, Cihan Papan,

We report a series of Staphylococcus argenteus infections from Saarland, Germany. Travel histories were unremarkable for extra-European sojourns, indicating an autochthonous transmission mode. Multilocus sequence typing revealed that all isolates were members of the clonal complex CC2250. In only one case, guideline-adherent treatment with an isoxazolyl penicillin was prescribed. Our ... Read more >>

Eur. J. Clin. Microbiol. Infect. Dis. (European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology)
[2020, :]

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How is the microbial diagnosis of bacterial vertebral osteomyelitis performed? An 11-year retrospective study.

Marie Amsilli, Olivier Epaulard,

Vertebral osteomyelitis (VOM) is often diagnosed with delays, resulting in poorer outcomes. Microbial documentation is particularly challenging and obtained using blood cultures (BCs) and vertebral biopsies (VBs; CT-guided or surgical). We retrospectively analysed VOM cases in a tertiary reference centre between 2004 and 2015, focusing on how and how quickly ... Read more >>

Eur. J. Clin. Microbiol. Infect. Dis. (European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology)
[2020, :]

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Management and outcomes of Burkholderia cepacia complex bacteremia in patients without cystic fibrosis: a retrospective observational study.

Yu-Mi Lee, Ki-Ho Park, Chisook Moon, Dong Youn Kim, Mi Suk Lee, Tark Kim, Eun Ju Choo, Yong Pil Chong, Sung-Han Kim, Yang Soo Kim, Jun Hee Woo, Mee Soo Chang,

Burkholderia cepacia complex (BCC) is an emerging pathogen of nosocomial infection in chronic or critically ill patients without cystic fibrosis (CF). The objective was to evaluate the management and outcomes of BCC bacteremia in patients without CF. We conducted a retrospective study of non-CF adult patients with BCC bacteremia between ... Read more >>

Eur. J. Clin. Microbiol. Infect. Dis. (European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology)
[2020, :]

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Infection caused by Sporothrix schenckii: an autochthonous case in Bari, Southern Italy.

Rosa Monno, Gaetano Brindicci, Orazio Romeo, Elena De Carolis, Giuseppe Criseo, Maurizio Sanguinetti, Luciana Fumarola, Giuseppe Ingravallo, Michele Mariani, Laura Monno,

An autochthonous case of lymphocutaneous sporotrichosis caused by Sporothrix schenckii is reported. The patient developed skin lesions localized along the lymphatics that appeared after he suffered an injury while collecting wicker canes in marshy water. The fungus was identified as Sporothrix schenckii by MALDI-TOF and sequencing. Phylogenetic analysis was also ... Read more >>

Eur. J. Clin. Microbiol. Infect. Dis. (European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology)
[2020, :]

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Is Porphyromonas gingivalis involved in Parkinson's disease?

Ingar Olsen, Douglas B Kell, Etheresia Pretorius,

Porphyromonas gingivalis, a major subgingival plaque bacterium in periodontitis, has recently attracted much attention as a possible microbial driver in Alzheimer's disease. In the present paper, another common neuroinflammatory disease, Parkinson's disease (PD), is discussed. A recent study found major virulence factors of P. gingivalis such as gingipain R1 (RgpA) ... Read more >>

Eur. J. Clin. Microbiol. Infect. Dis. (European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology)
[2020, :]

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Detection of anti-Pneumocystis jirovecii antibodies in human serum using a recombinant synthetic multi-epitope kexin-based antigen.

Ana Luísa Tomás, Fernando Cardoso, Bruno de Sousa, Olga Matos,

Interest in the detection of specific anti-Pneumocystis jirovecii antibodies has emerged as less-invasive alternative diagnostic approaches. Here is presented the performance of an ELISA based on a recombinant synthetic multi-epitope kexin 1 (Kex1) antigen of P. jirovecii, previously developed. Results showed that IgM anti-Kex1 levels were found significantly increased in ... Read more >>

Eur. J. Clin. Microbiol. Infect. Dis. (European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology)
[2020, :]

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Virulence of Helicobacter pylori outer membrane proteins: an updated review.

Chenjing Xu, Djaleel Muhammad Soyfoo, Yao Wu, Shunfu Xu,

Helicobacter pylori (H. pylori) infection is associated with some gastric diseases, such as gastritis, peptic ulcer, and gastric cancer. CagA and VacA are known virulence factors of H. pylori, which play a vital role in severe clinical outcomes. Additionally, the expression of outer membrane proteins (OMPs) helps H. pylori attach ... Read more >>

Eur. J. Clin. Microbiol. Infect. Dis. (European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology)
[2020, :]

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Effect of angiotensin II blockers on the prognosis of COVID-19: a toxicological view.

Farshad M Shirazi, Shireen Banerji, Samaneh Nakhaee, Omid Mehrpour,

Eur. J. Clin. Microbiol. Infect. Dis. (European Journal of Clinical Microbiology & Infectious Diseases)
[2020, :]

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Epidemiology of skeletal tuberculosis in Beijing, China: a 10-year retrospective analysis of data.

Jun Fan, Jun An, Wei Shu, Fengmin Huo, Shanshan Li, Fen Wang, Shibing Qin, Yu Pang,

Skeletal tuberculosis (STB) is one of the most common forms of extrapulmonary tuberculosis; however, limited epidemiological data are available on this public health concern worldwide, especially in developing countries. The aims of this study were to analyze the epidemiological characteristics of STB cases and to identify risk factors associated with ... Read more >>

Eur. J. Clin. Microbiol. Infect. Dis. (European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology)
[2020, :]

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Clinical characteristics and outcomes of Staphylococcus aureus bacteremia from a biliary source.

Eunmi Yang, Jeongsoo Lee, Hyeonji Seo, Hyemin Chung, Sang Hyun Ra, Heungsup Sung, Mi-Na Kim, Jiwon Jung, Min Jae Kim, Sung-Han Kim, Sang-Oh Lee, Sang-Ho Choi, Jun Hee Woo, Yang Soo Kim, Yong Pil Chong,

Staphylococcus aureus is a virulent gram-positive organism, which rarely involves the biliary tract. This study aimed to analyze the clinical characteristics and outcomes of S. aureus bacteremia (SAB) originating from the biliary tract by comparing them with those of catheter-related SAB and biliary Klebsiella pneumoniae bacteremia. A matched case-control study ... Read more >>

Eur. J. Clin. Microbiol. Infect. Dis. (European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology)
[2020, :]

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Evaluation of rapid polymyxin Nordmann Poirel test for detection of polymyxin resistance in clinical isolates of Enterobacteriaceae.

Muhammad Shoaib, Ashfaq Hussain, Luqman Satti, Wajid Hussain, Gohar Zaman, Faisal Hanif,

Polymyxins play a significant role against carbapenem-resistant Enterobacteriaceae (CRE). A total of 121 clinical samples yielded growth of CRE that were included in the study. Rapid Polymyxin NP test was performed on all the isolates as described by Nordmann P et al. and results were compared with broth microdilution method. ... Read more >>

Eur. J. Clin. Microbiol. Infect. Dis. (European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology)
[2020, :]

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A comparison of GenomEra® GBS PCR and GeneXpert ® GBS PCR assays with culture of GBS performed with and without broth pre-enrichment.

S Y Nielsen, J K Møller, M R Khalil,

This study was designed to compare the performance of GeneXpert® and GenomEra® group B streptococcus (GBS) PCR assays, held up against standard culture of GBS performed with and without broth pre-enrichment. In Denmark, the strategy for preventing early onset GBS infection (EOGBS) is risk factor based. Three hundred and sixty ... Read more >>

Eur. J. Clin. Microbiol. Infect. Dis. (European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology)
[2020, :]

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