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Journal Eur Urol

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Male Overactive Bladder: Underappreciated, Under-researched. More Please?

Adrian Wagg,

Eur Urol (European urology)
[2021, :]

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New Insights into Hypospadias: Next-generation Sequencing Reveals Potential Genetic Factors in Male Urethral Development.

Laurence S Baskin,

Eur Urol (European urology)
[2021, :]

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Histologic Grading of Bladder Tumors: Using Both the 1973 and 2004/2016 World Health Organization Systems in Combination Provides Valuable Information for Establishing Prognostic Risk Groups.

Timothy D Jones, Liang Cheng,

Eur Urol (European urology)
[2021, :]

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A Systematic Review of Patients' Values, Preferences, and Expectations for the Diagnosis and Treatment of Male Lower Urinary Tract Symptoms.

Sachin Malde, Roland Umbach, Jessica R Wheeler, Lyubov Lytvyn, Jean-Nicholas Cornu, Mauro Gacci, Christian Gratzke, Thomas R W Herrmann, Charalampos Mamoulakis, Malte Rieken, Mark J Speakman, Stavros Gravas, Marcus J Drake, Gordon H Guyatt, Kari A O Tikkinen,

<h4>Context</h4>Understanding men's values and preferences in the context of personal, physical, emotional, relational, and social factors is important in optimising patient counselling, facilitating treatment decision-making, and improving guideline recommendations.<h4>Objective</h4>To systematically review the available evidence regarding the values, preferences, and expectations of men towards the investigation and treatment (conservative, pharmacological, and ... Read more >>

Eur Urol (European urology)
[2021, :]

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Adjuvant Pazopanib Versus Placebo After Nephrectomy in Patients With Localized or Locally Advanced Renal Cell Carcinoma: Final Overall Survival Analysis of the Phase 3 PROTECT Trial.

Robert J Motzer, Paul Russo, Naomi Haas, Christian Doehn, Frede Donskov, Marine Gross-Goupil, Sergei Varlamov, Evgeny Kopyltsov, Jae Lyun Lee, Ho Yeong Lim, Bohuslav Melichar, Milada Zemanova, Brian Rini, Toni K Choueiri, Lori Wood, M Neil Reaume, Arnulf Stenzl, Simon Chowdhury, Ray McDermott, Agnieszka Michael, Miguel Izquierdo, Paola Aimone, Hong Zhang, Cora N Sternberg, ,

Most studies indicate no benefit of adjuvant therapy with VEGFR tyrosine kinase inhibitors in advanced renal cell carcinoma (RCC). PROTECT (NCT01235962) was a randomized, double-blind, placebo-controlled phase 3 study to evaluate adjuvant pazopanib in patients with locally advanced RCC at high risk of relapse after nephrectomy (pazopanib, n = 769; placebo, n = 769). ... Read more >>

Eur Urol (European urology)
[2021, :]

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Assessing Value-based Health Care Initiatives in Urology.

Parth K Modi, David O Meltzer,

Eur Urol (European urology)
[2021, :]

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How Far Should We Explore Hypospadias? Next-generation Sequencing Applied to a Large Cohort of Hypospadiac Patients.

Vuthy Ea, Anne Bergougnoux, Pascal Philibert, Nadège Servant-Fauconnet, Alice Faure, Jean Breaud, Laura Gaspari, Charles Sultan, Françoise Paris, Nicolas Kalfa,

<h4>Background</h4>Next-generation sequencing (NGS) is generally used for patients with severe disorders of sex development (DSD). However, NGS has not been applied extensively for patients with hypospadias only, and most affected children do not benefit from an etiological diagnosis.<h4>Objective</h4>To evaluate the clinical usefulness of NGS for patients with hypospadias, regardless of ... Read more >>

Eur Urol (European urology)
[2021, :]

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The Who, What, When, Where, and Why of Bacillus Calmette-Guérin-unresponsive Bladder Cancer.

Roger Li, Seth P Lerner, Ashish M Kamat,

There are several clinical scenarios that may not adhere to the precise definition of bacillus Calmette-Guérin (BCG)-unresponsive bladder cancer, but nevertheless indicate treatment unresponsiveness. We describe four such scenarios as a frame of reference in order to reach a consensus on the enrollment of such patients to current and future ... Read more >>

Eur Urol (European urology)
[2021, :]

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Robot-assisted Radical Cystectomy Versus Open Radical Cystectomy in Bladder Cancer Patients: A Multicentre Comparative Effectiveness Study.

Carl J Wijburg, Charlotte T J Michels, Gerjon Hannink, Janneke P C Grutters, Maroeska M Rovers, J Alfred Witjes, ,

<h4>Background</h4>Radical cystectomy with pelvic lymph node dissection (PLND) and urinary diversion in patients with bladder cancer is known for its high risk of complications. Although open radical cystectomy (ORC) is regarded as the standard treatment, robot-assisted radical cystectomy (RARC) is increasingly used in practice, despite the fact that high-quality evidence ... Read more >>

Eur Urol (European urology)
[2021, :]

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Actinium-225 Prostate-specific Membrane Antigen Theranostics: Will α Beat β?

Nattakorn Dhiantravan, Michael S Hofman, Aravind S Ravi Kumar,

Optimisation of prostate-specific membrane antigen (PSMA) based radioligand therapy (RLT) requires a focus on prospective trials. ... Read more >>

Eur Urol (European urology)
[2021, :]

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Reply to Christian Daniel Fankhauser, Arie Parnham, Vijay Sangar's Letter to the Editor re: Paolo Dell'Oglio, Hielke M. de Vries, Elio Mazzone, et al. Hybrid Indocyanine Green-99mTc-nanocolloid for Single-photon Emission Computed Tomography and Combined Radio- and Fluorescence-guided Sentinel Node Biopsy in Penile Cancer: Results of 740 Inguinal Basins Assessed at a Single Institution. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2020.09.007.

Paolo Dell'Oglio, Hielke M de Vries, Elio Mazzone, Gijs H KleinJan, Maarten L Donswijk, Henk G van der Poel, Simon Horenblas, Fijs W B van Leeuwen, Oscar R Brouwer,

Eur Urol (European urology)
[2021, :]

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Insulinemic and Inflammatory Dietary Patterns and Risk of Prostate Cancer.

Benjamin C Fu, Fred K Tabung, Claire H Pernar, Weike Wang, Amparo G Gonzalez-Feliciano, Ilkania M Chowdhury-Paulino, Steven K Clinton, Edmund Folefac, Mingyang Song, Adam S Kibel, Edward L Giovannucci, Lorelei A Mucci,

<h4>Background</h4>Hyperinsulinemia and inflammation are inter-related pathways that link diet with the risk of several chronic diseases. Evidence suggests that these pathways may also increase prostate cancer risk.<h4>Objective</h4>To determine whether hyperinsulinemic diet and inflammatory diet are associated with prostate cancer incidence and mortality.<h4>Design, setting, and participants</h4>We prospectively followed 41 209 men ... Read more >>

Eur Urol (European urology)
[2021, :]

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Re: Fredrik Liedberg, Petter Kollberg, Marie Allerbo, et al. Preventing Parastomal Hernia After Ileal Conduit by the Use of a Prophylactic Mesh: A Randomised Study. Eur Urol 2020;78:757-63.

Amit Bansal, Ruchir Maheshwari, Anant Kumar,

Eur Urol (European urology)
[2021, :]

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Reply to Salma Kaochar, Nicholas Mitsiades' Letter to the Editor re: Umang Swami, Pedro Isaacsson Velho, Roberto Nussenzveig, et al. Association of SPOP Mutations with Outcomes in Men with De Novo Metastatic Castration-sensitive Prostate Cancer. Eur Urol 2020, 78:652-6. Can Mutant SPOP Become an Actionable Biomarker for Precision Oncology Management of Prostate Cancer?: SPOP as a Potential Treatment Selection Marker in Prostate Cancer.

Umang Swami, Emmanuel S Antonarakis, Neeraj Agarwal,

Eur Urol (European urology)
[2021, :]

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Quantitative and Qualitative Analysis of Blood-based Liquid Biopsies to Inform Clinical Decision-making in Prostate Cancer.

Irene Casanova-Salas, Alejandro Athie, Paul C Boutros, Marzia Del Re, David T Miyamoto, Kenneth J Pienta, Edwin M Posadas, Adam G Sowalsky, Arnulf Stenzl, Alexander W Wyatt, Joaquin Mateo,

<h4>Context</h4>Genomic stratification can impact prostate cancer (PC) care through diagnostic, prognostic, and predictive biomarkers that aid in clinical decision-making. The temporal and spatial genomic heterogeneity of PC together with the challenges of acquiring metastatic tissue biopsies hinder implementation of tissue-based molecular profiling in routine clinical practice. Blood-based liquid biopsies are ... Read more >>

Eur Urol (European urology)
[2021, :]

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European Association of Urology (EAU) Prognostic Factor Risk Groups for Non-muscle-invasive Bladder Cancer (NMIBC) Incorporating the WHO 2004/2016 and WHO 1973 Classification Systems for Grade: An Update from the EAU NMIBC Guidelines Panel.

Richard J Sylvester, Oscar Rodríguez, Virginia Hernández, Diana Turturica, Lenka Bauerová, Harman Max Bruins, Johannes Bründl, Theo H van der Kwast, Antonin Brisuda, José Rubio-Briones, Maximilian Seles, Anouk E Hentschel, Venkata R M Kusuma, Nicolai Huebner, Juliette Cotte, Laura S Mertens, Dimitrios Volanis, Olivier Cussenot, Jose D Subiela Henríquez, Enrique de la Peña, Francesca Pisano, Michael Pešl, Antoine G van der Heijden, Sonja Herdegen, Alexandre R Zlotta, Jaromir Hacek, Ana Calatrava, Sebastian Mannweiler, Judith Bosschieter, David Ashabere, Andrea Haitel, Jean-François Côté, Soha El Sheikh, Luca Lunelli, Ferran Algaba, Isabel Alemany, Francesco Soria, Willemien Runneboom, Johannes Breyer, Jakko A Nieuwenhuijzen, Carlos Llorente, Luca Molinaro, Christina A Hulsbergen-van de Kaa, Matthias Evert, Lambertus A L M Kiemeney, James N'Dow, Karin Plass, Otakar Čapoun, Viktor Soukup, Jose L Dominguez-Escrig, Daniel Cohen, Joan Palou, Paolo Gontero, Maximilian Burger, Richard Zigeuner, Amir Hugh Mostafid, Shahrokh F Shariat, Morgan Rouprêt, Eva M Compérat, Marko Babjuk, Bas W G van Rhijn,

<h4>Background</h4>The European Association of Urology (EAU) prognostic factor risk groups for non-muscle-invasive bladder cancer (NMIBC) are used to provide recommendations for patient treatment after transurethral resection of bladder tumor (TURBT). They do not, however, take into account the widely used World Health Organization (WHO) 2004/2016 grading classification and are based ... Read more >>

Eur Urol (European urology)
[2021, :]

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Reply to Anirban P. Mitra, Tanner Miest, and Colin P.N. Dinney's Words of Wisdom re: Genomic Predictors of Good Outcome, Recurrence, or Progression in High-Grade T1 Non-Muscle-Invasive Bladder Cancer. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2020.10.020.

Júlia Perera-Bel, Joaquim Bellmunt,

Eur Urol (European urology)
[2021, :]

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Standardization in Surgical Education (SISE): Development and Implementation of an Innovative Training Program for Urologic Surgery Residents and Trainers by the European School of Urology in Collaboration with the ESUT and EULIS Sections of the EAU.

Bhaskar Somani, Ton Brouwers, Domenico Veneziano, Ali Gözen, Kamran Ahmed, Evangelos Liatsikos, Kemal Sarica, Joan Palou, Jens Rassweiler, Chandra Shekhar Biyani, Tiago Ribeiro de Oliveira, Alex Mottrie, Anthony Gallagher, Alberto Breda, Hein van Poppel, Craig McIllhenney, Michiel Sedelaar, Stefano Puliatti, Sunjay Jain, Rosanne van Loenen, Ben van Cleynenbreugel,

Eur Urol (European urology)
[2021, :]

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Re: Health Related Quality of Life of Patients with Bladder Cancer in the RAZOR Trial: A Multi-institutional Randomized Trial Comparing Robot Versus Open Radical Cystectomy.

Gianluca Giannarini, Claudio Valotto, Vincenzo Ficarra,

Eur Urol (European urology)
[2021, :]

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Re: The Patient Beyond the Sphincter-Cognitive and Functional Considerations Affecting the Natural History of Artificial Urinary Sphincters.

Daniel S Elliott,

Eur Urol (European urology)
[2021, :]

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The Mutational Landscape of Metastatic Castration-sensitive Prostate Cancer: The Spectrum Theory Revisited.

Matthew P Deek, Kim Van der Eecken, Ryan Phillips, Neil R Parikh, Pedro Isaacsson Velho, Tamara L Lotan, Amar U Kishan, Tobias Maurer, , Paul C Boutros, Christopher Hovens, Matthew Abramowtiz, Alan Pollack, Neil Desai, Bradley Stish, Felix Y Feng, Mario Eisenberger, Michael Carducci, Kenneth J Pienta, Mark Markowski, Channing J Paller, Emmanuel S Antonarakis, Alejandro Berlin, Piet Ost, Phuoc T Tran,

<h4>Background</h4>Emerging data suggest that metastasis is a spectrum of disease burden rather than a binary state, and local therapies, such as radiation, might improve outcomes in oligometastasis. However, current definitions of oligometastasis are solely numerical.<h4>Objective</h4>To characterize the somatic mutational landscape across the disease spectrum of metastatic castration-sensitive prostate cancer (mCSPC) ... Read more >>

Eur Urol (European urology)
[2021, :]

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Value-Based Healthcare in Urology: A Collaborative Review.

Chanan Reitblat, Paul A Bain, Michael E Porter, David N Bernstein, Thomas W Feeley, Markus Graefen, Santosh Iyer, Matthew J Resnick, C J Stimson, Quoc-Dien Trinh, Boris Gershman,

<h4>Context</h4>In response to growing concerns over rising costs and major variation in quality, improving value for patients has been proposed as a fundamentally new strategy for how healthcare should be delivered, measured, and remunerated.<h4>Objective</h4>To systematically review the literature regarding the implementation and impact of value-based healthcare in urology.<h4>Evidence acquisition</h4>A systematic ... Read more >>

Eur Urol (European urology)
[2021, :]

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Re: Avelumab Maintenance Therapy for Advanced or Metastatic Urothelial Carcinoma.

Georgios Gakis,

Eur Urol (European urology)
[2020, :]

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The Association Between Statin Use and Outcomes in Patients Initiating Androgen Deprivation Therapy.

Robert J Hamilton, Keyue Ding, Juanita M Crook, Christopher J O'Callaghan, Celestia S Higano, David P Dearnaley, Eric M Horwitz, S Larry Goldenberg, Mary K Gospodarowicz, Laurence Klotz,

<h4>Background</h4>Studies have conflicting results regarding the association between statin use and biochemical recurrence for prostate cancer (PCa). A limited number of studies examining statins in advanced stages report positive results, with a few specifically examining statins and androgen deprivation therapy (ADT).<h4>Objective</h4>To perform a post hoc secondary analysis of a randomised ... Read more >>

Eur Urol (European urology)
[2020, :]

Cited: 0 times

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Re: Paolo Dell'Oglio, Hielke M. de Vries, Elio Mazzone, et al. Hybrid Indocyanine Green-99mTc-nanocolloid for Single-photon Emission Computed Tomography and Combined Radio- and Fluorescence-guided Sentinel Node Biopsy in Penile Cancer: Results of 740 Inguinal Basins Assessed at a Single Institution. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2020.09.007.

Christian D Fankhauser, Arie Parnham, Vijay Sangar,

Eur Urol (European urology)
[2021, :]

Cited: 0 times

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