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Journal Early Interv Psychiatry

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Establishing a clinical high-risk program in Tunisia, North Africa: A pilot study in early detection and identification.

Joseph Ventura, Lamia Jouini, Amina Aissa, Amine Larnaout, Rahma Nefzi, Malek Ghazzai, Sélima Jelili, Feten Fekih-Romdhane, Uta Ouali, Fethi Nacef,

<h4>Background</h4>Early identification and prevention research has provided huge advances in our understanding of early screening and identification of young people at clinical high-risk (CHR). Most of these procedures were developed in high-income countries, yet middle-income countries in North Africa such as Tunisia can benefit from these empirically-based assessment approaches.<h4>Methods</h4>Using established ... Read more >>

Early Interv Psychiatry (Early intervention in psychiatry)
[2021, :]

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How can mental health practitioners collaborate with child welfare practitioners to improve mental health for young people in out of home care?

Katherine Monson, Helen Herrman, Kristen Moeller-Saxone, Cathy Humphreys, Carol Harvey,

<h4>Background</h4>Young people who grow up in out of home care have higher risk of poor mental health outcomes than peers who grow up with their family-of-origin. Interagency collaboration is an important service-level intervention to improve access to mental healthcare. However, few descriptions of collaboration provide guidance about collaboration between individual ... Read more >>

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[2021, :]

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Integration of biological and psychological illness attributional belief in association with medication adherence behaviour: A path analysis.

Yi Nam Suen, Emily Tsz Wa Yeung, Sherry Kit Wa Chan, Christy Lai Ming Hui, Edwin Ho Ming Lee, Wing Chung Chang, Candice Yu Hay Chan, Chan Eric Yu Hai Chen,

<h4>Aim</h4>This study aimed to determine the association of biological (BAB) and psychological illness attributional beliefs (PAB) with medication adherence behaviour in patients with psychosis in Hong Kong.<h4>Methods</h4>A cross-sectional survey of 301 outpatients with psychosis in Hong Kong was conducted from August to October 2016. The survey included a set of ... Read more >>

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[2021, :]

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Comparison of clinical characteristics and treatment efficacy in childhood-onset schizophrenia and adolescent-onset schizophrenia in mainland China: A retrospective study.

Xin Cheng, Huihui Zhang, Jiuping Zhang, Ping Xu, Peiying Jin, Hui Fang, Kangkang Chu, Xiaoyan Ke,

<h4>Aim</h4>The comparative study of childhood-onset schizophrenia (COS) and adolescent-onset schizophrenia (AOS) is scarce. This study aimed to examine the differences in clinical presentations and treatment efficacy between COS and AOS and further analyse the factors affecting the efficacy of early-onset schizophrenia (EOS).<h4>Methods</h4>A total of 582 electronic medical records of inpatients ... Read more >>

Early Interv Psychiatry (Early intervention in psychiatry)
[2021, :]

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Effects of COVID-19 pandemic on mental health outcomes in a cohort of early psychosis patients.

Alejandro G Szmulewicz, Nicole M Benson, John Hsu, Miguel A Hernán, Dost Öngür,

<h4>Aim</h4>To evaluate the impact of the COVID-19 pandemic on clinical outcomes, we used data from Electronic Health Records from 128 patients receiving care at a First Episode Psychosis clinic.<h4>Methods</h4>Rates of admission or emergency room (ER) visits from January 2020 to July 2020 were analysed using difference-in-difference regression. We used the ... Read more >>

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[2021, :]

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Non-suicidal self-injury is associated with psychotic like experiences, depression, and bullying in Korean adolescents.

Ju-Yeon Lee, Honey Kim, Seon-Young Kim, Jae-Min Kim, Il-Seon Shin, Sung-Wan Kim,

<h4>Aim</h4>Non-suicidal self-injury (NSSI) is common among adolescents, and several different factors can affect its prevalence. The present study examined the associated characteristics predicting NSSI among adolescents in South Korea.<h4>Methods</h4>In total, 1674 high school students were recruited for a cross-sectional survey. They completed self-reported assessments, including the Deliberate Self-Harm Inventory (DSHI), ... Read more >>

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[2021, :]

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Comparison of antipsychotic naïve first-episode psychosis patients and healthy controls in Uganda.

Emmanuel K Mwesiga, Dickens Akena, Nastassja Koen, Juliet Nakku, Noeline Nakasujja, Dan J Stein,

<h4>Introduction</h4>The risk factors for a first episode of psychosis in low and middle-income countries (LMICs) are not well described. The study compared the association of different risk factors in patients with first-episode psychosis patients and healthy controls from an LMIC context.<h4>Methods</h4>A comparative, descriptive, cross-sectional study was performed in antipsychotic naïve ... Read more >>

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[2021, :]

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Clinical effectiveness of early treatment with paliperidone palmitate in schizophrenia: A retrospective real-world study in South Korea.

Wonsuk Shin, Dong Hyeon Lee, Min-Kyoung Kim, Sang-Hyuk Lee, Doo-Yeoun Cho, Minji Bang,

<h4>Aim</h4>Long-acting injectable antipsychotic agents (LAIs) including paliperidone palmitate (PP) have shown promising results in preventing relapse and rehospitalization in schizophrenia. This study aimed to ascertain the comparative real-world effectiveness between the early and late administration of PP and oral formulations of risperidone and paliperidone (ORPs) in patients experiencing a first ... Read more >>

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[2021, :]

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Cognitive behavioural social skills training: Methods of a randomized controlled trial for youth at risk of psychosis.

Jean Addington, Lu Liu, Olga Santesteban-Echarri, Kali Brummitt, Amy Braun, Kristin S Cadenhead, Barbara A Cornblatt, Jason L Holden, Eric Granholm,

<h4>Aim</h4>Poor functioning has become a hallmark of many youth at clinical high-risk (CHR) of psychosis. Even for those who do not make the transition to psychosis remain troubled by functional deficits and a decline in functioning increases the odds of transitioning to psychosis. There are very few treatment studies that ... Read more >>

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[2021, :]

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Looking within: Interoceptive sensibility in young adults with psychotic-like experiences.

Mariapaola Barbato, Teresa Arora, Shaikha Al Hemeiri, Maryam A AlJassmi,

<h4>Aim</h4>Interoception is the ability to sense internal bodily changes and research indicates that it may play a role in the development of mental illness. In recent years, preliminary evidence has shown that interoception is impaired in people with psychosis. Interoceptive sensibility, a meta-cognitive aspect of interoception, has never been studied ... Read more >>

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[2021, :]

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A systematic mapping review of interventions to improve adolescent mental health literacy, attitudes and behaviours.

Brittany Patafio, Peter Miller, Ryan Baldwin, Nicholas Taylor, Shannon Hyder,

<h4>Aim</h4>The onset of mental illness is most common in adolescence, therefore mental health promotion efforts frequently target this age group. Evaluation literature in this area is largely segmented into specific domains in terms of settings, countries, and/or groups of young people, but an overall understanding and comparison across these areas ... Read more >>

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[2021, :]

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Clinician stakeholder experiences of a new youth mental health model in Australia: A qualitative study.

Louise Nash, Sophie Isobel, Margaret Thomas, Thao Nguyen, Renae van der Pol,

<h4>Aim</h4>Late teens and early adulthood is the peak age of onset for mental disorders. Currently, there is a gap between primary mental health care and more intensive mental health services for young people in New South Wales (NSW), Australia. Two headspace Early Intervention Teams (hEITs) were developed to bridge this ... Read more >>

Early Interv Psychiatry (Early intervention in psychiatry)
[2021, :]

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Heterogeneity in the co-occurrence of depression and anxiety symptoms among youth survivors: A longitudinal study using latent profile analysis.

Yue Wang, Fenfen Ge, Jun Zhang, Wei Zhang,

<h4>Aim</h4>Depression and anxiety are both common psychological outcomes triggered via trauma-related experience. The current study aimed to identify the prevalence of depression and anxiety among youth survivors, explore the heterogeneity patterns of depression and anxiety symptoms in the chronic phase, and integrate early available information to predict patterns.<h4>Methods</h4>The study is ... Read more >>

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[2021, :]

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Prevalence and predictors of suicidality and non-suicidal self-harm among individuals at clinical high-risk for psychosis: Results from a community-recruited sample.

Kate Haining, Olga Karagiorgou, Ruchika Gajwani, Joachim Gross, Andrew I Gumley, Stephen M Lawrie, Matthias Schwannauer, Frauke Schultze-Lutter, Peter J Uhlhaas,

<h4>Aim</h4>Suicidal thoughts and behaviours are prevalent in individuals with schizophrenia. However, research examining the prevalence and predictors of suicidality and self-harm in participants at clinical high-risk for psychosis (CHR-P) is limited and mostly focuses on help-seeking participants recruited through clinical pathways. The current study sought to assess the prevalence of ... Read more >>

Early Interv Psychiatry (Early intervention in psychiatry)
[2020, :]

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The youth online training and employment system: Study protocol for a randomized controlled trial of an online vocational intervention for young people with mental ill health.

Magenta B Simmons, Jennifer Nicholas, Gina Chinnery, Shaunagh O'Sullivan, Simon D'Alfonso, Sarah Bendall, Daniela Cagliarini, Matthew Hamilton, John Gleeson, Eóin Killackey, Mario Alvarez-Jimenez,

<h4>Aim</h4>People diagnosed with mental disorders experience higher rates of unemployment than those without. Career adaptability, defined as the ability to respond flexibly and make informed career decisions in work and throughout career transitions, is becoming increasingly important as the nature of work changes rapidly. Early vocational intervention may ameliorate poor ... Read more >>

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[2021, :]

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A network examination of risky behaviours in a state-level and national epidemiological sample of high school students.

Caroline Christian, Ani C Keshishian, Cheri A Levinson, Nicholas C Peiper,

<h4>Aim</h4>Engagement in risky behaviours, including substance use, disordered eating, suicidal behaviour, and peer victimization/violence, during adolescence is becoming increasingly prevalent. These risky behaviours are highly comorbid and associated with long-term consequences for health, relationships, and socioeconomic status, representing an important public health concern. Past research has primarily investigated risky behaviours ... Read more >>

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[2021, :]

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Cause for concern: Australian youth engaged with alcohol and other drug services are falling behind our community progress in reducing tobacco use.

Karen Tracey Hallam, Madeline Wishart, Ora Davidson,

<h4>Aim</h4>Tobacco use is decreasing in the general youth population yet little evidence is tracking changes in young people who are engaged with youth alcohol and other drug (AOD) services that are often disengaged from school and wok settings.<h4>Method</h4>This study reviews tobacco use amongst 1823 young people engaged with youth AOD ... Read more >>

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[2021, :]

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Cognitive functioning in first episode psychosis. Gender differences and relation with clinical variables.

Regina Vila-Badia, Núria Del Cacho, Anna Butjosa, Susana Ochoa, Clara Serra-Arumí, Marina Esteban-Sanjusto, Marta Pardo, Montserrat Dolz, Ariadna Casado-Ortega, Marta Coromina, , Judith Usall,

<h4>Aims</h4>to study the differences in cognitive functioning in patients and controls. In addition, study the influence of symptoms, cannabis consumption, chlorpromazine doses, DUP and IQ in cognitive performance in patients, both in the total sample and divided by gender.<h4>Methods</h4>70 first episode psychosis patients and 63 healthy controls (HC) participated in ... Read more >>

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[2020, :]

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ReMind, a smartphone application for psychotic relapse prediction: A longitudinal study protocol.

Christy Lai-Ming Hui, Bertha Sze-Ting Lam, Andreas Kar-Hin Wong, Tiffany Junchen Tao, Elise Chun-Ning Ho, Yi-Nam Suen, Edwin Ho-Ming Lee, Sherry Kit-Wa Chan, Wing-Chung Chang, Catherine Shiu-Yin Chong, Clara Man-Wah Siu, William Tak-Lam Lo, Eric Yu-Hai Chen,

<h4>Background</h4>Psychotic disorders are associated with a high rate of relapse. In addition to medication non-adherence, some psychosocial factors have been found to be predictive of relapse (e.g., poor premorbid adjustment, high expressed emotion and substance misuse). Impairments in cognitive functions including general memory functioning, set shifting, attention, processing speed and ... Read more >>

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[2020, :]

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Personal and contextual components of resilience mediate risky family environment's effect on psychotic-like experiences.

Rodolfo Rossi, Alberto Collazzoni, Dalila Talevi, Dino Gibertoni, Eleonora Quarta, Alessandro Rossi, Paolo Stratta, Giorgio Di Lorenzo, Francesca Pacitti,

<h4>Background</h4>Psychotic-like experiences (PLEs) index an increased risk for subsequent psychotic disorders. A risky family environment is a well-established risk factor for PLEs; however, different contextual and personal resiliency factors may differentially mediate its effect on PLEs.<h4>Objective</h4>In this study, we propose a two-dimensional model of resilience. Our aim is to address ... Read more >>

Early Interv Psychiatry (Early intervention in psychiatry)
[2020, :]

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Duration of untreated illness of patients with obsessive-compulsive disorder in Japan.

Yoshihiro Matsumoto, Takashi Nakamae, Yoshinari Abe, Anri Watanabe, Jin Narumoto,

<h4>Aim</h4>Obsessive-compulsive disorder (OCD) is a common and severe disease; however, the duration of untreated illness (DUI) of OCD is approximately 7 years, which is longer than that of other psychiatric disorders. Differences in medical environments have been reported to affect the DUI. Therefore, we surveyed the DUI of OCD in Japan ... Read more >>

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[2020, :]

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The MAC-P program: A pilot study of a mindfulness and compassion program for youth with psychotic experiences.

Tara Hickey, Barnaby Nelson, Joanne Enticott, Graham Meadows,

<h4>Background</h4>The purpose of this pilot study was to determine the feasibility, acceptability and the potential clinical utility of a novel mindfulness and compassion program (MAC-P) designed for youth with a range of psychotic experiences.<h4>Method</h4>A non-randomised, non-controlled prospective follow-up study was conducted. Eighteen participants who either met criteria for the 'at ... Read more >>

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[2020, :]

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Group therapy via videoconferencing for individuals with early psychosis: A pilot study.

Tania Lecomte, Amal Abdel-Baki, Audrey Francoeur, Briana Cloutier, Amélie Leboeuf, Pascale Abadie, Marie Villeneuve, Stephane Guay,

<h4>Aim</h4>The COVID-19 pandemic has introduced many mental health professionals to therapy via videoconferencing. Mostly individual teletherapy has been offered and studied, although group therapy is often offered in clinics. In fact, little is known regarding group therapy's acceptability, feasibility, and potential impact when offered via videoconferencing.<h4>Methods</h4>This pilot study offered group ... Read more >>

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[2020, :]

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Retinal dysfunctions in a patient with a clinical high risk for psychosis and severe visual disturbances: A single case report.

Florent Bernardin, Thomas Schwitzer, Karine Angioi-Duprez, Anne Giersch, Fabienne Ligier, Stéphanie Bourion-Bedes, Claire Jansen, Raymund Schwan, Vincent Laprevote,

<h4>Aim</h4>Psychosis can be preceded by a clinical high risk for psychosis (CHR) and visual anomalies are predictors of transition to psychosis. Visual retinal processing is altered in psychosis, but no study has explored the links between visual symptoms and retinal functions in CHR patients. We report here the case of ... Read more >>

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[2020, :]

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A randomized Phase II trial evaluating efficacy, safety, and tolerability of oral BI 409306 in attenuated psychosis syndrome: Design and rationale.

Richard S E Keefe, Scott W Woods, Tyrone D Cannon, Stephan Ruhrmann, Daniel H Mathalon, Philip McGuire, Holger Rosenbrock, Kristen Daniels, Daniel Cotton, Dooti Roy, Stephane Pollentier, Michael Sand,

<h4>Aim</h4>Attenuated psychosis syndrome (APS), a condition for further study in the Diagnostic and Statistical Manual of Mental Disorders-5, comprises psychotic symptoms that are qualitatively similar to those observed in schizophrenia but are less severe. Patients with APS are at high risk of converting to first-episode psychosis (FEP). As evidence for ... Read more >>

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[2020, :]

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