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Journal Dtsch. Med. Wochenschr.

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[Muscle pain and muscle weakness - an interdisciplinary challenge].

Elisabeth Märker-Hermann,

Dtsch. Med. Wochenschr. (Deutsche medizinische Wochenschrift (1946))
[2020, 145(13):871]

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[Idiopathic Inflammatory Myopathies].

Stylianos Tomaras, Jörn Kekow, Eugen Feist,

Myositis is a rare and an extremely heterogeneous autoimmune disease, that causes muscle weakness. Currently, "idiopathic inflammatory myopathies (IIM)" is the preferred umbrella-term used to describe the disease complexity within individuals. IIM include dermatomyositis, polymyositis, inclusion body myositis, autoimmune necrotizing myopathy, overlap myositis and antisynthetase syndrome. Research activity concerning myositis ... Read more >>

Dtsch. Med. Wochenschr. (Deutsche medizinische Wochenschrift (1946))
[2020, 145(13):903-910]

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[Invasive Mechanical Ventilation Therapy in the Dying Process - Step by Step].

Jacqueline Schwartz, Stefan Meier, Steffen Simon, Guido Michels,

Invasive mechanical ventilation can be terminated by immediate (palliative) extubation or by gradual reduction of ventilation with the ventilation access left open (terminal weaning). Both procedures are ethically equivalent and can be performed in everyday life, so that individual patient factors and the experience of the treatment team are decisive. ... Read more >>

Dtsch. Med. Wochenschr. (Deutsche medizinische Wochenschrift (1946))
[2020, 145(13):926-931]

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[Non-inflammatory muscle pain].

Hannes Roicke, Wolfgang Köhler, Petra Baum, Christoph Baerwald, Marco Krasselt,

Muscle pain as a common symptom in daily practice frequently occurs as a non-specific accompanying symptom in multiple internal and neurological diseases. Primarily inflammatory or autoimmune muscular diseases are causing muscle pain. However, a number of non-inflammatory causes of pain can also be considered for differential diagnosis. These are presented ... Read more >>

Dtsch. Med. Wochenschr. (Deutsche medizinische Wochenschrift (1946))
[2020, 145(13):887-894]

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[COVID-19: Variable symptoms in mild course: olfactory loss and increased resting heart rate].

Anna Isenmann, Stefan Isenmann,

HISTORY: A 56-year-old, previously healthy male and long distance runner noticed short episodes of parosmia, followed by anosmia. Few days later, he monitored an increase in his resting heart rate. This was followed by a dry cough, fatigue, and myalgia. At the same time, symptoms occurred in all four family members. ... Read more >>

Dtsch. Med. Wochenschr. (Deutsche medizinische Wochenschrift (1946))
[2020, :]

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[Mobility and Fall Prevention in older Community-dwelling Persons].

Ellen Freiberger, Cornel C Sieber, Katrin Singler,

An increasing proportion of oldest old persons (over 80 years) accompanies the demographic change. Furthermore, the gender ration will also change and the percentage of older men will increase. Mobility is an important factor for maintaining independence and for "healthy aging". Mobility has to be regarded in the context of individual ... Read more >>

Dtsch. Med. Wochenschr. (Deutsche medizinische Wochenschrift (1946))
[2020, 145(13):932-943]

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[Inflammatory Muscle Pain: Polymyalgia Rheumatica with or without Large Vessel Vasculitis].

Wolfgang A Schmidt,

Polymyalgia rheumatica (PMR) is characterized by rapidly evolving shoulder and pelvic girdle pain with fatigue, weight loss, night sweats and elevated CRP and ESR. Giant cell arteritis (GCA) can occur in PMR and vice versa. Headache and scalp tenderness are typical for GCA. GCA may be complicated by visual loss ... Read more >>

Dtsch. Med. Wochenschr. (Deutsche medizinische Wochenschrift (1946))
[2020, 145(13):895-902]

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[Basic Knowledge of Drug Pain Therapy in the Palliative Situation].

Sascha Weber, Angelika Lampert, Julia Stingl, Vera Peuckmann-Post, Sonja Hiddemann, Frank Elsner, Irene Neuner, Roman Rolke,

This review provides an overview of the basic knowledge of drug pain therapy in the palliative situation. Pain is one of the main symptoms in 60 to 90 % of cancer patients. Pain also develops with neurological and other diseases that occur in end-of-life situations. To address this symptom, a holistic ... Read more >>

Dtsch. Med. Wochenschr. (Deutsche medizinische Wochenschrift (1946))
[2020, 145(13):917-925]

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[91-year-old patient with acute abdominal pain and diarrhea].

Klaus Muehlenberg, Oliver Pech, Niels Zorger,

Dtsch. Med. Wochenschr. (Deutsche medizinische Wochenschrift (1946))
[2020, 145(13):885-886]

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[Smoke-free Germany 2040: a discussion paper].

Reiner Hanewinkel, Matthis Morgenstern, Barbara Isensee, Friedrich J Wiebel,

INTRODUCTION: A "smoke-free" society is assumed if less than 5 % of a population smoke. We predict when this goal could be reached in Germany. To reduce the proportion of smokers in the population, the World Health Organization recommends a bundle of measures (MPOWER) that should minimize both the supply of and ... Read more >>

Dtsch. Med. Wochenschr. (Deutsche medizinische Wochenschrift (1946))
[2020, :]

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[Screening of Mothers in a COVID-19 Low-Prevalence Region: Determination of SARS-CoV-2 Antibodies in 401 Mothers from Rostock by ELISA and Confirmation by Immunofluorescence].

Emil C Reisinger, Ronald von Possel, Philipp Warnke, Hilte F Geerdes-Fenge, Christoph J Hemmer, Susanne Pfefferle, Micha Löbermann, Martina Littmann, Petra Emmerich,

BACKGROUND: In children, the infection with SARS-CoV-2, the cause of COVID-19, tends to be clinically inapparent more often or less severe than in adults. The spread of this infection from children poses a danger to vulnerable adults. Therefore, child care institutions and schools currently are widely closed. METHODS: Since the status of ... Read more >>

Dtsch. Med. Wochenschr. (Deutsche medizinische Wochenschrift (1946))
[2020, :]

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[Diagnosis and treatment of severe acute pancreatitis in critical care].

Theresa H Wirtz, Tobias Puengel, Lukas Buendgens, Tom Luedde, Christian Trautwein, Alexander Koch,

Acute pancreatitis is a potentially life-threatening disease that requires intensive care, especially in severe cases. The present article is intended to illustrate the possibilities of a rational diagnosis of acute pancreatitis as well as to provide an overview of the stage-adapted therapy, which includes both conservative measures and interventional interdisciplinary ... Read more >>

Dtsch. Med. Wochenschr. (Deutsche medizinische Wochenschrift (1946))
[2020, 145(12):850-862]

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[77-year-old patient with suspected coronary fistula: diagnostic work-up].

Christopher Kloth, Thomas Breining, Stefan Andreas Schmidt, Meinrad Beer, Horst Brunner,

Dtsch. Med. Wochenschr. (Deutsche medizinische Wochenschrift (1946))
[2020, 145(12):811-812]

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[Primary and Secondary Prevention of Multiple Myeloma - Lifestyle Factors and Supportive Measures].

David Cordas Dos Santos, Nicole Erickson, Lars Gerland, Franziska Jundt, Sebastian Theurich,

Lifestyle factors such as diet, physical activity and exposure to noxious agents are modifiable factors that have a significant impact on the state of health and life expectancy of humans. The following article is intended to provide an overview of current knowledge on the influence of these lifestyle factors on ... Read more >>

Dtsch. Med. Wochenschr. (Deutsche medizinische Wochenschrift (1946))
[2020, 145(12):836-842]

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[Multiple Myeloma: better prognosis thanks timely and effective treatment].

Michael von Bergwelt-Baildon, Sebastian Theurich,

Dtsch. Med. Wochenschr. (Deutsche medizinische Wochenschrift (1946))
[2020, 145(12):799]

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[Recurrent Therapy of Multiple Myeloma - Individualized Concepts from The Arsenal of Diverse Options].

Charlotte Weyermann, Christian Straka, Hermann Einsele,

The prognosis of patients with multiple myeloma has improved significantly over the past 20 years. However, the patient population in the relapse situation is very heterogeneous due to increasing age and the previous course of the disease and therapy. In particular, the approval of new targeted substances offers numerous treatment ... Read more >>

Dtsch. Med. Wochenschr. (Deutsche medizinische Wochenschrift (1946))
[2020, 145(12):820-827]

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[Onconephrology - Interdisciplinary Cooperation of Nephrologists and Oncologists in the Treatment of Multiple Myeloma].

Ulf Schönermarck, Marcus Hentrich, Florian Bassermann, Sebastian Theurich, Michael Fischereder,

Plasma cell diseases, in particular multiple myeloma, represent an interdisciplinary challenge for oncologists and nephrologists. Patients often present initially with kidney problems to a nephrologist, requiring timely diagnosis and referral to an oncologist for treatment. On the other hand, a relevant part of patients will experience a - mostly temporary ... Read more >>

Dtsch. Med. Wochenschr. (Deutsche medizinische Wochenschrift (1946))
[2020, 145(12):828-835]

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[Federal Act on Participation: Opportunities for people with severe obesity].

Maxi Florentine Siebert, Alwin Baumann, Martin Wabitsch,

BACKGROUND: Children and adolescents with severe obesity suffer from significant disadvantages in many areas of life. Equal participation in life in society is hardly possible for this group of people. In order to counteract this, it was examined whether children and adolescents with severe obesity are considered disabled under the Social ... Read more >>

Dtsch. Med. Wochenschr. (Deutsche medizinische Wochenschrift (1946))
[2020, 145(12):863-867]

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[Current Recommendations for the First-Line Therapy of Symptomatic Multiple Myeloma].

Lukas John, Hartmut Goldschmidt, Christof Scheid,

Due to the introduction of novel therapeutic agents, the prognosis of Multiple Myeloma has greatly improved over the last decades. The current standard for fit patients is a bortezomib-based induction therapy, followed by high-dose chemotherapy and autologous stem cell transplantation and lenalidomide-based maintenance therapy. For older, non-transplant-eligible patients, daratumumab in ... Read more >>

Dtsch. Med. Wochenschr. (Deutsche medizinische Wochenschrift (1946))
[2020, 145(12):813-819]

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[Paraneoplastic Cushing's syndrome as cause of refractory hypokalemia].

Louisa M S Gerhardt, Lisa Sabath, Beat Müller, Joel Capraro, Katrin Borm,

HISTORY: A 58-year-old man presented with refractory hypokalemia and rapid weight gain. On examination, he had high blood pressure, central obesity and bilateral pitting edema. FINDINGS AND DIAGNOSIS: Biochemical tests showed hypokalemic metabolic alkalosis due to ACTH-dependent hypercortisolism. CT of thorax and abdomen revealed a pulmonary and a right adrenal mass. Biopsy ... Read more >>

Dtsch. Med. Wochenschr. (Deutsche medizinische Wochenschrift (1946))
[2020, 145(11):783-786]

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[Cardiac biomarkers and COVID-19 - Phenotypes and Interpretation].

Christian Salbach, Evangelos Giannitsis,

Current pandemic caused by SARS-CoV-2 inducing viral COVID-19 pneumonia, is categorized in 3 stages. Some biomarkers could be assigned to one of these stages, showing a correlation to mortality in COVID-19 patients. Laboratory findings in COVID-19, especially when serially evaluated, may represent individual disease severity and prognosis. These may help ... Read more >>

Dtsch. Med. Wochenschr. (Deutsche medizinische Wochenschrift (1946))
[2020, 145(11):755-760]

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[News for usage of albumin in patients with liver disease].

Carla Cremonese, Frank Erhard Uschner, Jonel Trebicka,

The recommended indications for short-term use of human albumin in patients with decompensated cirrhosis are the following: prevention of paracenteses induced circulatory dysfunction, treatment of hypovolemia, prevention of hepatorenal syndrome in high-risk patients with spontaneous bacterial peritonitis, as well as treatment of hepatorenal syndrome. Liver cirrhosis is associated with systemic ... Read more >>

Dtsch. Med. Wochenschr. (Deutsche medizinische Wochenschrift (1946))
[2020, 145(11):722-726]

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[40-year-old woman with headache of unknown origin].

Jakob Leonhardi, Cordula Scherlach, Karl-Titus Hoffmann,

Dtsch. Med. Wochenschr. (Deutsche medizinische Wochenschrift (1946))
[2020, 145(11):781-782]

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[Acquired immune thrombocytopenia: An update on aspects of diagnosis and management relevant for intensive care medicine].

Oleg Hidiatov, Jan Zlamal, Parwez Aidery, Tamam Bakchoul,

Acquired thrombocytopenias represent a group of bleeding diseases, which can be mediated by immune or non-immune factors. Acquired immune thrombocytopenia (AITP) leads to an accelerated decrease in platelet count by platelet reactive antibodies arising from several mechanisms. In AITP, autoantibodies, alloantibodies or drug-dependent antibodies are usually targeting platelet surface glycoproteins. ... Read more >>

Dtsch. Med. Wochenschr. (Deutsche medizinische Wochenschrift (1946))
[2020, 145(11):747-753]

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[Primary aldosteronism - why is it still underdiagnosed in clinical practice?]

Laura Handgriff, Martin Reincke,

Primary aldosteronism (PA) represents the leading cause of endocrine hypertension, accounting for 4-13 % of all cases. Simultaneously, it is the most common endocrine form of hypertension that can be cured by surgery. Estimates suggest that 2.5 million people in Germany are affected, yet only 8 % of hypertensive patients undergo the proper ... Read more >>

Dtsch. Med. Wochenschr. (Deutsche medizinische Wochenschrift (1946))
[2020, 145(11):716-721]

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