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Acute Closed-Angle Glaucoma-an Ophthalmological Emergency.

Simone Nüssle, Thomas Reinhard, Jan Lübke,

<h4>Background</h4>Acute closed-angle glaucoma has an incidence of 2.2-4.1 cases per 100 000 persons per year in Europe. It is an ophthalmological emergency in which markedly elevated intraocular pressure can damage vision permanently. Because the acute symptoms are not always clearly referable to the eyes, patients often present to physicians who ... Read more >>

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2021, (Forthcoming):]

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Wound Closure After Port Implantation-a Randomized Controlled Trial Comparing Tissue Adhesive and Intracutaneous Suturing.

Saskia Witting, Maja Ingwersen, Thomas Lehmann, René Aschenbach, Niklas Eckardt, Jürgen Zanow, René Fahrner, Stephan Lotze, Reinhard Friedel, Mark Lenz, Claudia Schmidt, Diana Miguel, Laine Ludriksone, Ulf Teichgräber,

<h4>Background</h4>Wound healing after pectoral port implantation is a major factor determining the success or failure of the procedure. Infection and wound dehiscence can endanger the functionality of the port system and impede chemotherapy. The cosmetic result is important for patient satisfaction as well.<h4>Methods</h4>From August 2015 to July 2017, adult patients ... Read more >>

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2021, (Forthcoming):]

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Health Literacy in Germany-Findings of a Representative Follow-up Survey.

Doris Schaeffer, Eva-Maria Berens, Dominique Vogt, Svea Gille, Lennert Griese, Julia Klinger, Klaus Hurrelmann,

<h4>Background</h4>Studies have shown that the health literacy of the German population is low. The aim of this article is to analyze current developments in health literacy on the basis of recent data.<h4>Methods</h4>The Health Literacy Survey Germany 2 (HLS-GER 2) is a representative quantitative survey of the German-speaking resident population of ... Read more >>

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2021, (Forthcoming):]

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Imaging of Prostate Cancer.

Heinz-Peter Schlemmer, Bernd Joachim Krause, Viktoria Schütz, David Bonekamp, Sarah Schwarzenböck, Markus Hohenfellner,

<h4>Background</h4>Prostate cancer is the most common type of solid tumor in men and the second most common cause of cancer-related death in males in Germany. The conventional strategy for its primary detection, i.e., systematic ultrasound-guided prostate biopsy in men who have elevated PSA levels and/or positive findings on digital rectal ... Read more >>

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2021, (Forthcoming):]

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Drug Safety for Nursing-Home Residents - Findings of a Pragmatic, Cluster-Randomized, Controlled Intervention Trial in 44 Nursing Homes.

Ulrike Junius-Walker, Olaf Krause, Petra Thürmann, Simone Bernhard, Angela Fuchs, Lisa Sparenberg, Anja Wollny, Regina Stolz, Hannah Haumann, Antje Freytag, Claudia Kirsch, Svetlana Usacheva, Stefan Wilm, Birgitt Wiese, ,

<h4>Background</h4>The safety of drug use by nursing-home residents can be impaired by polypharmacy, potentially inappropriate medications (PIM), and neuroleptics, as well as by a lack of adequate interprofessional coordination in the nursing home. The goal of the HIOPP-3- iTBX Trial was to improve drug safety in nursing-home residents, including a ... Read more >>

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2021, (Forthcoming):]

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Scabies: Epidemiology, Diagnosis, and Treatment.

Cord Sunderkötter, Johannes Wohlrab, Henning Hamm,

<h4>Background</h4>Scabies is a skin infestation whose incidence is apparently rising.<h4>Methods</h4>This review is based on pertinent articles retrieved by a selective search of PubMed on diagnosis and treatment strategies.<h4>Results</h4>Thread-like papules (burrows), new, intense pruritus, and dermatitis guide the suspected diagnosis which is confirmed by the microscopic or dermatoscopic demonstration of scabies ... Read more >>

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2021, (Forthcoming):]

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An Automated Electronic Screening Tool (DETECT) for the Detection of Potentially Irreversible Loss of Brain Function.

Anne Trabitzsch, Konrad Pleul, Kristian Barlinn, Volkmar Franz, Markus Dengl, Monica Götze, Andreas Güldner, Maria Eberlein-Gonska, Detlev Michael Albrecht, Christian Hugo,

<h4>Background</h4>A major reason for the low number of organ donors in Germany is a deficit in the recognition of patients who may have impending irreversible loss of brain function (ILBF) in hospitals capable of organ retrieval.<h4>Methods</h4>We used anonymized data from the German Organ Procurement Organization (Deutsche Stiftung Organtransplantation, DSO) to ... Read more >>

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2021, (Forthcoming):]

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Osteoporotic Fractures of the Thoracic and Lumbar Vertebra: Diagnosis and Conservative Treatment-A Systematic Review.

Ulrich Spiegl, Hartmut Bork, Sebastian Grüninger, Uwe Maus, Georg Osterhoff, Max J Scheyerer, Philipp Pieroh, Jörg Schnoor, Christoph-Eckhard Heyde, Klaus J Schnake,

<h4>Background</h4>The prevalence of osteoporotic vertebral body fractures in Europe is 18-26%. Although most of these injuries can be treated conservatively, the underlying concepts have not been defined clearly or uniformly. In this article, we present the current state of the evidence on the diagnosis and conservative treatment of osteoporotic fractures ... Read more >>

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2021, (Forthcoming):]

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The Incidence of Fractures Among the Adult Population of Germany – and Analysis From 2009 through 2019.

Markus Rupp, Nike Walter, Christian Pfeifer, Siegmund Lang, Maximilian Kerschbaum, Werner Krutsch, Florian Baumann, Volker Alt,

<h4>Background</h4>Detailed analyses of epidemiological data on fractures are an important resource for persons and institutions providing health care services, as they yield information on the effects of current treatment strategies and on the need for preventive measures. The epidemiology of fractures in Germany, however, is unknown. The goal of this ... Read more >>

Dtsch Arztebl Int (Deutsches Arzteblatt international)
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Visual Phenomena Associated With Migraine and Their Differential Diagnosis.

Ozan E Eren, Helmut Wilhelm, Christoph J Schankin, Andreas Straube,

<h4>Background</h4>Visual phenomena are of many different kinds; their differential diagnosis is usually possible with directed history-taking. In this review, we describe common visual phenomena that must be distinguished from a migraine aura.<h4>Methods</h4>This review is based on publications retrieved by a selective search in PubMed and the Web of Knowledge/Science, with ... Read more >>

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2021, (Forthcoming):]

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Clinical Practice Guideline: Complementary Medicine in the Treatment of Cancer Patients.

Jutta Hübner, Matthias Beckmann, Markus Follmann, Monika Nothacker, Franz Josef Prott, Bernhard Wörmann,

<h4>Background</h4>Approximately half of all patients with cancer use at least one method of complementary medicine during or after tumor treatment. The substances most commonly taken are micronutrients, food supplements, and plant extracts.<h4>Methods</h4>This guideline is based on pertinent articles retrieved by a systematic search in the Medline, Cochrane Library, Embase, PsycInfo, ... Read more >>

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2021, (Forthcoming):]

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Mitochondrial Disorders.

Thomas Klopstock, Claudia Priglinger, Ali Yilmaz, Cornelia Kornblum, Felix Distelmaier, Holger Prokisch,

<h4>Background</h4>Mitochondrial disorders are among the most common heritable diseases, with an overall lifetime risk of approximately one in 1500. Nonetheless, their diagnosis is often missed because of their extreme phenotypic and genotypic heterogeneity.<h4>Methods</h4>This review is based on publications retrieved by a selective literature search on the clinical features, genetics, pathogenesis, ... Read more >>

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2021, (Forthcoming):]

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The Effect of an Abdominal Binder on Postoperative Pain after Laparoscopic Incisional Hernia Repair-A Multicenter, Randomized Pilot Trial (ABIHR-I) of the Intraperitoneal Onlay-Mesh Technique.

Christoph Paasch, Gianluca De Santo, Nouf Aljedani, Pedro Ortiz, Lisa Bruckert, Michael Hünerbein, Eric Lorenz, Roland Croner,

<h4>Background</h4>Incisional hernias with apertures measuring less than 7 cm can generally be treated adequately with the laparoscopic intraperitoneal onlay-mesh (IPOM) technique. The wearing of an abdominal binder after surgery is often recommended in order to promote wound healing and prevent recurrent herniation. We carried out a multicenter, randomized pilot trial ... Read more >>

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2021, (Forthcoming):]

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Coronary In-Stent Restenosis–Predictors and Treatment.

Helen Ullrich, Maximilian Olschewski, Thomas Münzel, Tommaso Gori,

<h4>Background</h4>Despite the use of modern drug-eluting stents (DES), in-stent restenosis (ISR) may still occur in as many as 2-10% of percutaneous coronary interventions (PCI) in certain lesion/patient subsets. ISR causes increased morbidity after stent implantation; acute myocardial infarction is a frequent correlate to a clinical ISR, arising in 5-10% of ... Read more >>

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2021, (Forthcoming):]

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Acute Pulmonary Embolism–Its Diagnosis and Treatment From a Multidisciplinary Viewpoint.

Hannah C Kulka, Andreas Zeller, Jürgen Fornaro, Walter A Wuillemin, Stavros Konstantinides, Michael Christ,

<h4>Background</h4>Physicians from many different specialties see patients suffering from acute pulmonary embolism (PE), which has an incidence of 39-115 cases per 100 000 persons per year. Because PE can be life-threatening, a rapid, targeted response is essential.<h4>Methods</h4>This review is based on pertinent publications retrieved by a selective literature search of ... Read more >>

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2021, (Forthcoming):]

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Blood sugar targets in surgical intensive care—management and special considerations in patients with diabetes

Johannes Roth, Oliver Sommerfeld, Andreas L Birkenfeld, Christoph Sponholz, Ulrich A Müller, Christian von Loeffelholz,

<h4>Background</h4>30-80% of patients being treated in intensive care units in the perioperative period develop hyperglycemia. This stress hyperglycemia is induced and maintained by inflammatoryendocrine and iatrogenic stimuli and generally requires treatment. There is uncertainty regarding the optimal blood glucose targets for patients with diabetes mellitus.<h4>Methods</h4>This review is based on pertinent ... Read more >>

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2021, 118(Forthcoming):]

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Fifth Metatarsal Fracture-A Systematic Review of the Treatment of Fractures of the Base of the Fifth Metatarsal Bone.

Viktoria Herterich, Sebastian Felix Baumbach, Antonia Kaiser, Wolfgang Böcker, Hans Polzer,

<h4>Background</h4>Metatarsal fractures are among the most common foot and ankle injuries, with an annual incidence of 6.7 per 100 000 persons. Approximately 30% of metatarsal fractures affect the base of the fifth metatarsal bone. Nevertheless, no evidence-based treatment recommendations are available to date.<h4>Methods</h4>The three fracture localizations according to Lawrence and ... Read more >>

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2021, (Forthcoming):]

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Studies for the evaluation of diagnostic tests—part 28 of a series on evaluation of scientific publications.

Annika Hoyer, Antonia Zapf,

<h4>Background</h4>The accurate diagnosis of a disease is a prerequisite for its appropriate treatment. How well a medical test is able to correctly identify or rule out a target disease can be assessed by diagnostic accuracy studies.<h4>Methods</h4>The main statistical parameters that are derived from diagnostic accuracy studies, and their proper interpretation, ... Read more >>

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2021, 118(Forthcoming):]

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Extravasation Injuries of the Limbs in Neonates and Children-Development of a Treatment Algorithm.

Roslind K Hackenberg, Koroush Kabir, Andreas Müller, Andreas Heydweiller, Christof Burger, Kristian Welle,

<h4>Background</h4>Hospitalized children and neonates very often receive intravenous treatment. There has not yet been any systematic study of the incidence of extravasation injuries in this age group. In a few studies of neonates in intensive care receiving intravenous treatment, incidence figures in the range of 18-46% have been reported; 2.4-4% ... Read more >>

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2021, (Forthcoming):]

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Upper Gastrointestinal Bleeding from an Aberrant Left Subclavian Artery with Fatal Outcome.

Gerhard Rümenapf, Peter Bodrogi, Thomas Rabenstein,

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2021, 118(31-32):543]

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Trends Over Time in Breast-Cancer-Specific Mortality in Germany.

Annika Waldmann, Joachim Hübner, Alexander Katalinic,

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2021, 118(31-32):538-539]

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Adults Born Preterm.

Dominique Singer, Luise Pauline Thiede, Anna Perez,

<h4>Background</h4>Advances in neonatology now enable increasing numbers of very low birth weight neonates (<1500 g) to survive into early adulthood and beyond. What are the implications for their long-term care?<h4>Methods</h4>Selective literature search on the outcome of very low birth weight neo - nates in adulthood ("adults born preterm").<h4>Results</h4>Robust data are ... Read more >>

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2021, 118(31-32):521-527]

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The Importance of Urine Cytology.

Ines Rathert,

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2021, 118(31-32):544-545]

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Delayed Diagnosis of Bacterial Infections during the Pandemic with Fatal Course.

Bonaventura Schmid, Hans-Jörg Busch, Corinna N Lang, Dawid L Staudacher, Jörg Bayer,

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2021, 118(31-32):542]

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In Reply.

Jan Hendrik Oltrogge,

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2021, 118(31-32):542-543]

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