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Not Just Another Headache: Cerebral Venous Sinus Thrombosis in a Patient With Isolated Antithrombin III Deficiency.

Dawood Findakly, Jack Komro,

Cerebral venous sinus thrombosis (CVST) is a rare condition. Symptoms and signs arise from a combination of thrombosis of cerebral veins and increased intracranial pressure. The most common presenting symptom is a non-descriptive headache, but presentation varies with underlying etiology. CVST requires a high index of suspicion to diagnose, particularly ... Read more >>

Cureus (Cureus)
[2020, 12(5):]

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Not Just Another Headache: Cerebral Venous Sinus Thrombosis in a Patient With Isolated Antithrombin III Deficiency.

Dawood Findakly, Jack Komro,

Cerebral venous sinus thrombosis (CVST) is a rare condition. Symptoms and signs arise from a combination of thrombosis of cerebral veins and increased intracranial pressure. The most common presenting symptom is a non-descriptive headache, but presentation varies with underlying etiology. CVST requires a high index of suspicion to diagnose, particularly ... Read more >>

Cureus (Cureus)
[2020, 12(5):e8383]

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Misdiagnosis of Small Cell Prostate Cancer: Lessons Learned.

Dawood Findakly, Jue Wang,

Small cell carcinoma (SCC) of the prostate is rare in the spectrum of prostate tumors. Clinically, prostate SCC is more aggressive and has a poorer prognosis when compared to prostate acinar adenocarcinoma. Delay in diagnosis and misdiagnosis further worsens the outcome of this disease. Here we present a 68-year-old man ... Read more >>

Cureus (Cureus)
[2020, 12(5):e8356]

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Protective Adaptive Immunity Against Severe Acute Respiratory Syndrome Coronaviruses 2 (SARS-CoV-2) and Implications for Vaccines.

Christopher Manners, Erick Larios Bautista, Hannah Sidoti, Osvaldo J Lopez,

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an emerging human coronavirus responsible for coronavirus disease 2019 (COVID-19), a predominantly respiratory disease that has become a global pandemic. Millions of people worldwide are suffering from COVID-19, and hundreds of thousands of those infected have died. Nevertheless, many more people who ... Read more >>

Cureus (Cureus)
[2020, 12(6):e8399]

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Protective Adaptive Immunity Against Severe Acute Respiratory Syndrome Coronaviruses 2 (SARS-CoV-2) and Implications for Vaccines.

Christopher Manners, Erick Larios Bautista, Hannah Sidoti, Osvaldo J Lopez,

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an emerging human coronavirus responsible for coronavirus disease 2019 (COVID-19), a predominantly respiratory disease that has become a global pandemic. Millions of people worldwide are suffering from COVID-19, and hundreds of thousands of those infected have died. Nevertheless, many more people who ... Read more >>

Cureus (Cureus)
[2020, 12(6):]

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Misdiagnosis of Small Cell Prostate Cancer: Lessons Learned.

Dawood Findakly, Jue Wang,

Small cell carcinoma (SCC) of the prostate is rare in the spectrum of prostate tumors. Clinically, prostate SCC is more aggressive and has a poorer prognosis when compared to prostate acinar adenocarcinoma. Delay in diagnosis and misdiagnosis further worsens the outcome of this disease. Here we present a 68-year-old man ... Read more >>

Cureus (Cureus)
[2020, 12(5):]

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Staphylococcus warneri: Skin Commensal and a Rare Cause of Urinary Tract Infection.

Aparna Kanuparthy, Tejo Challa, Sreenath Meegada, Suman Siddamreddy, Vijayadershan Muppidi,

Coagulase negative Staphylococci often grow in cultures and form one of the most abundant flora among skin microbiome. It is important and challenging to identify and treat clinically significant infections caused by these organisms. Prosthetic devices, catheters and conditions causing immunocompromised states are the risk factors for such infections. We ... Read more >>

Cureus (Cureus)
[2020, 12(5):]

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Jejunal Diverticulosis Complicated by Diverticulitis and Small Bowel Obstruction.

Yousef Elfanagely, Chung Sang Tse, Priyanka Patil, Stephanie Lueckel,

Diverticular disease is common in the Western population and can cause considerable morbidity. The prevalence of colonic diverticulosis reaches 60% by the age of 60 years. Small bowel diverticulosis is much rarer and, when present, most commonly occurs in the duodenum. We herein report an elderly woman with jejunal diverticulosis complicated by ... Read more >>

Cureus (Cureus)
[2020, 12(5):]

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Recurrence of Pheochromocytoma With Metastases After Resection of Primary Tumor.

Sharini Venugopal, Mamta Chhabria, Michael Quartuccio,

Pheochromocytomas and paragangliomas are rare tumors that arise from the chromaffin cells of the adrenal medulla or sympathetic paravertebral ganglia, respectively. Long-term surveillance is recommended regardless of the thoroughness of surgical resection. Here, we present a patient who was diagnosed with pheochromocytoma who underwent right adrenalectomy and was lost to ... Read more >>

Cureus (Cureus)
[2020, 12(5):e8328]

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Tumor Lysis Syndrome in Solid Tumors: A Comprehensive Literature Review, New Insights, and Novel Strategies to Improve Outcomes.

Dawood Findakly, Ross D Luther, Jue Wang,

Tumor lysis syndrome (TLS) is a life-threatening oncological condition that is typically characterized by metabolic derangements that are often labeled as an acute kidney injury. The recent advancement in cancer treatment has led to the mounting rate of TLS in solid tumors that were previously rarely linked to this complication. ... Read more >>

Cureus (Cureus)
[2020, 12(5):]

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Optimizing Computed Tomography for Detection of Pulmonary Thromboembolism in Patients With Fontan Circulation.

Sohab Radwan, Gauravpal S Gill, Amre Ghazzal, Christopher Barnett,

Congenital heart disease (CHD) patients who have undergone the Fontan procedure or one of its variants usually have altered vascular anatomy. Consequently, this poses a challenge when diagnosing pulmonary thromboembolism (PTE) with computed tomography (CT). Detailed review of the type of surgery performed and the person’s individual anatomy beforehand can help ... Read more >>

Cureus (Cureus)
[2020, 12(5):]

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Vaccines and Drug Therapeutics to Lock Down Novel Coronavirus Disease 2019 (COVID-19): A Systematic Review of Clinical Trials.

Akshaya S Bhagavathula, Wafa A Aldhaleei, Alessandro Rovetta, Jamal Rahmani,

The ongoing novel coronavirus disease 2019 (COVID-19) pandemic has been responsible for millions of infections and hundreds of thousands of deaths. To date, there is no approved targeted treatment, and many investigational therapeutic agents and vaccine candidates are being considered for the treatment of COVID-19. To extract and summarize information ... Read more >>

Cureus (Cureus)
[2020, 12(5):e8342]

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Staphylococcus warneri: Skin Commensal and a Rare Cause of Urinary Tract Infection.

Aparna Kanuparthy, Tejo Challa, Sreenath Meegada, Suman Siddamreddy, Vijayadershan Muppidi,

Coagulase negative Staphylococci often grow in cultures and form one of the most abundant flora among skin microbiome. It is important and challenging to identify and treat clinically significant infections caused by these organisms. Prosthetic devices, catheters and conditions causing immunocompromised states are the risk factors for such infections. We ... Read more >>

Cureus (Cureus)
[2020, 12(5):e8337]

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Managing Acute Portal Hypertensive Gastropathy Bleed During the Time of COVID-19 Pandemic: Novelty or Necessity?

Cyriac A Philips, Sandeep Kumbar, Rizwan Ahamed, Philip Augustine,

Acute bleeding from portal hypertensive gastropathy (PHG) is an extremely rare event in the natural history of cirrhosis. The treatment recommendations include portal pressure reduction strategies including pharmacotherapy with vasoactive agents and beta-blockers and interventional strategies such as transjugular intrahepatic portosystemic shunt placement. In this report, we present the case ... Read more >>

Cureus (Cureus)
[2020, 12(5):e8333]

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Recurrence of Pheochromocytoma With Metastases After Resection of Primary Tumor.

Sharini Venugopal, Mamta Chhabria, Michael Quartuccio,

Pheochromocytomas and paragangliomas are rare tumors that arise from the chromaffin cells of the adrenal medulla or sympathetic paravertebral ganglia, respectively. Long-term surveillance is recommended regardless of the thoroughness of surgical resection. Here, we present a patient who was diagnosed with pheochromocytoma who underwent right adrenalectomy and was lost to ... Read more >>

Cureus (Cureus)
[2020, 12(5):]

Cited: 0 times

View full text PDF listing >>



Optimizing Computed Tomography for Detection of Pulmonary Thromboembolism in Patients With Fontan Circulation.

Sohab Radwan, Gauravpal S Gill, Amre Ghazzal, Christopher Barnett,

Congenital heart disease (CHD) patients who have undergone the Fontan procedure or one of its variants usually have altered vascular anatomy. Consequently, this poses a challenge when diagnosing pulmonary thromboembolism (PTE) with computed tomography (CT). Detailed review of the type of surgery performed and the person's individual anatomy beforehand can help ... Read more >>

Cureus (Cureus)
[2020, 12(5):e8326]

Cited: 0 times

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Jejunal Diverticulosis Complicated by Diverticulitis and Small Bowel Obstruction.

Yousef Elfanagely, Chung Sang Tse, Priyanka Patil, Stephanie Lueckel,

Diverticular disease is common in the Western population and can cause considerable morbidity. The prevalence of colonic diverticulosis reaches 60% by the age of 60 years. Small bowel diverticulosis is much rarer and, when present, most commonly occurs in the duodenum. We herein report an elderly woman with jejunal diverticulosis complicated by ... Read more >>

Cureus (Cureus)
[2020, 12(5):e8347]

Cited: 0 times

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Managing Acute Portal Hypertensive Gastropathy Bleed During the Time of COVID-19 Pandemic: Novelty or Necessity?

Cyriac A Philips, Sandeep Kumbar, Rizwan Ahamed, Philip Augustine,

Acute bleeding from portal hypertensive gastropathy (PHG) is an extremely rare event in the natural history of cirrhosis. The treatment recommendations include portal pressure reduction strategies including pharmacotherapy with vasoactive agents and beta-blockers and interventional strategies such as transjugular intrahepatic portosystemic shunt placement. In this report, we present the case ... Read more >>

Cureus (Cureus)
[2020, 12(5):]

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Acute Fulminant Hepatic Failure and Renal Failure Induced by Oral Amiodarone: A Case Report and Literature Review.

Natasha Campbell, Khushboo Agarwal, Marjan Alidoost, Jeffrey A Miskoff, Mohammad Hossain,

Amiodarone is a class III antiarrhythmic agent that inhibits adrenergic stimulation by blocking alpha and beta receptors. It prolongs action potential and refractory period in myocardial tissue. Its remarkably long half-life is associated with a myriad of adverse events. Here, we present an 85-year-old male patient who was started on ... Read more >>

Cureus (Cureus)
[2020, 12(5):]

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Prognostic Significance of Diastolic Dysfunction With Multiple Comorbidities in Heart Failure Patients.

Baldeep Mann, Janpreet S Bhandohal, Savi Mushiyev,

Background Heart failure poses a significant burden on health care and economy. In recent years, diastolic dysfunction has been increasingly recognized as a significant predictor of readmission in heart failure patients. Objectives We aimed to identify factors predicting readmission in patients with clinical heart failure at 30 days and six ... Read more >>

Cureus (Cureus)
[2020, 12(5):e8297]

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Prognostic Significance of Diastolic Dysfunction With Multiple Comorbidities in Heart Failure Patients.

Baldeep Mann, Janpreet S Bhandohal, Savi Mushiyev,

BackgroundHeart failure poses a significant burden on health care and economy. In recent years, diastolic dysfunction has been increasingly recognized as a significant predictor of readmission in heart failure patients.ObjectivesWe aimed to identify factors predicting readmission in patients with clinical heart failure at 30 days and six months.MethodsA retrospective chart ... Read more >>

Cureus (Cureus)
[2020, 12(5):]

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Tumor Lysis Syndrome in Solid Tumors: A Comprehensive Literature Review, New Insights, and Novel Strategies to Improve Outcomes.

Dawood Findakly, Ross D Luther, Jue Wang,

Tumor lysis syndrome (TLS) is a life-threatening oncological condition that is typically characterized by metabolic derangements that are often labeled as an acute kidney injury. The recent advancement in cancer treatment has led to the mounting rate of TLS in solid tumors that were previously rarely linked to this complication. ... Read more >>

Cureus (Cureus)
[2020, 12(5):e8355]

Cited: 0 times

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Ruptured Right Broad Ligament Ectopic Pregnancy in a Patient With Prior Right Salpingo-Oophorectomy: A Case Report.

Erum Azhar, Landen Green, Salma Mohammadi, Abdul Waheed,

Ectopic pregnancy can be a life-threatening cause of acute abdomen. Broad ligament pregnancy accounts for 1% of ectopic abdominal pregnancies and complications can be calamitous. This case report highlights a 27-year-old G2P0010 female who presented with amenorrhea and acute right lower quadrant and pelvic pain. By last menstrual period (LMP), she ... Read more >>

Cureus (Cureus)
[2020, 12(5):e8276]

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A Rare Clinical Presentation of Metastatic Crohn's Disease.

Kaitlyn L Streight, Tara L Braun, Nicholas Lowe, Soo Jung Kim,

A 31-year-old female with a history of systemic lupus erythematous, IgA nephropathy, and psoriasis presented with a one-month history of a painful, pruritic rash under the bilateral breasts and in the genital region. Cutaneous examination revealed a large, tender ulcer under the left breast with a shiny erythematous base and ... Read more >>

Cureus (Cureus)
[2020, 12(5):e8285]

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SMARCB1/INI1-Deficient Extrarenal Rhabdoid Tumor: A Case Report of a Rare and Aggressive Soft Tissue Sarcoma.

Nathaniel A Parker, Ammar Al-Obaidi, Daniel Lalich, Jeremy M Deutsch,

Malignant SMARCB1/INI1-deficient extrarenal rhabdoid tumors are aggressive tumors that are extremely rare in adults. A 56-year-old male presented with the chief complaints of unilateral lower abdominal and pelvic pain. He underwent urgent surgical intervention and mass resection with tissue sampling. After pathology confirmed the diagnosis, systemic chemotherapy with vincristine, doxorubicin plus ... Read more >>

Cureus (Cureus)
[2020, 12(5):e8273]

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