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Journal Crit Care Med

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The authors reply.

Rachael Parke, Shay McGuinness, ,

Crit Care Med (Critical care medicine)
[2021, 49(11):e1192-e1193]

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Osamudiamen O Obanor, Bryan T Romito,

Crit Care Med (Critical care medicine)
[2021, 49(11):e1181]

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Where Is Acute Physiology and Chronic Health Evaluation V?

Eric S Ringle, Maureen M Stark, Laura Freeseman-Freeman, Kathy N Henson,

Crit Care Med (Critical care medicine)
[2021, 49(11):e1176-e1177]

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Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021.

Laura Evans, Andrew Rhodes, Waleed Alhazzani, Massimo Antonelli, Craig M Coopersmith, Craig French, Flávia R Machado, Lauralyn Mcintyre, Marlies Ostermann, Hallie C Prescott, Christa Schorr, Steven Simpson, W Joost Wiersinga, Fayez Alshamsi, Derek C Angus, Yaseen Arabi, Luciano Azevedo, Richard Beale, Gregory Beilman, Emilie Belley-Cote, Lisa Burry, Maurizio Cecconi, John Centofanti, Angel Coz Yataco, Jan De Waele, R Phillip Dellinger, Kent Doi, Bin Du, Elisa Estenssoro, Ricard Ferrer, Charles Gomersall, Carol Hodgson, Morten Hylander Møller, Theodore Iwashyna, Shevin Jacob, Ruth Kleinpell, Michael Klompas, Younsuck Koh, Anand Kumar, Arthur Kwizera, Suzana Lobo, Henry Masur, Steven McGloughlin, Sangeeta Mehta, Yatin Mehta, Mervyn Mer, Mark Nunnally, Simon Oczkowski, Tiffany Osborn, Elizabeth Papathanassoglou, Anders Perner, Michael Puskarich, Jason Roberts, William Schweickert, Maureen Seckel, Jonathan Sevransky, Charles L Sprung, Tobias Welte, Janice Zimmerman, Mitchell Levy,

Crit Care Med (Critical care medicine)
[2021, 49(11):e1063-e1143]

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Transitions of Care After Critical Illness-Challenges to Recovery and Adaptive Problem Solving.

Kimberley J Haines, Elizabeth Hibbert, Nina Leggett, Leanne M Boehm, Tarli Hall, Rita N Bakhru, Anthony J Bastin, Brad W Butcher, Tammy L Eaton, Wendy Harris, Aluko A Hope, James Jackson, Annie Johnson, Janet A Kloos, Karen A Korzick, Pamela Mactavish, Joel Meyer, Ashley Montgomery-Yates, Tara Quasim, Andrew Slack, Dorothy Wade, Mary Still, Giora Netzer, Ramona O Hopkins, Theodore J Iwashyna, Mark E Mikkelsen, Joanne McPeake, Carla M Sevin, ,

<h4>Objectives</h4>Investigate the challenges experienced by survivors of critical illness and their caregivers across the transitions of care from intensive care to community, and the potential problem-solving strategies used to navigate these challenges.<h4>Design</h4>Qualitative design-data generation via interviews and data analysis via the framework analysis method.<h4>Setting</h4>Patients and caregivers from three continents, identified ... Read more >>

Crit Care Med (Critical care medicine)
[2021, 49(11):1923-1931]

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Cumulative Application of Creatinine and Urine Output Staging Optimizes the Kidney Disease: Improving Global Outcomes Definition and Identifies Increased Mortality Risk in Hospitalized Patients With Acute Kidney Injury.

Scott M Sutherland, Ahmad Kaddourah, Scott E Gillespie, Danielle E Soranno, Robert P Woroniecki, Rajit K Basu, Michael Zappitelli, ,

<h4>Objectives</h4>Acute kidney injury is diagnosed according to creatinine and urine output criteria. Traditionally, both are applied, and a severity stage (1-3) is conferred based upon the more severe of the two; information from the other criteria is discarded. Physiologically, however, rising creatinine and oliguria represent two distinct types of renal ... Read more >>

Crit Care Med (Critical care medicine)
[2021, 49(11):1912-1922]

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The authors reply.

Christopher Lai, Jean-Louis Teboul, Xavier Monnet,

Crit Care Med (Critical care medicine)
[2021, 49(11):e1185-e1186]

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The authors reply.

Osamudiamen O Obanor, Bryan T Romito,

Crit Care Med (Critical care medicine)
[2021, 49(11):e1179]

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Executive Summary: Surviving Sepsis Campaign: International Guidelines for the Management of Sepsis and Septic Shock 2021.

Laura Evans, Andrew Rhodes, Waleed Alhazzani, Massimo Antonelli, Craig M Coopersmith, Craig French, Flávia R Machado, Lauralyn Mcintyre, Marlies Ostermann, Hallie C Prescott, Christa Schorr, Steven Simpson, W Joost Wiersinga, Fayez Alshamsi, Derek C Angus, Yaseen Arabi, Luciano Azevedo, Richard Beale, Gregory Beilman, Emilie Belley-Cote, Lisa Burry, Maurizio Cecconi, John Centofanti, Angel Coz Yataco, Jan De Waele, R Phillip Dellinger, Kent Doi, Bin Du, Elisa Estenssoro, Ricard Ferrer, Charles Gomersall, Carol Hodgson, Morten Hylander Møller, Theodore Iwashyna, Shevin Jacob, Ruth Kleinpell, Michael Klompas, Younsuck Koh, Anand Kumar, Arthur Kwizera, Suzana Lobo, Henry Masur, Steven McGloughlin, Sangeeta Mehta, Yatin Mehta, Mervyn Mer, Mark Nunnally, Simon Oczkowski, Tiffany Osborn, Elizabeth Papathanassoglou, Anders Perner, Michael Puskarich, Jason Roberts, William Schweickert, Maureen Seckel, Jonathan Sevransky, Charles L Sprung, Tobias Welte, Janice Zimmerman, Mitchell Levy,

Crit Care Med (Critical care medicine)
[2021, 49(11):1974-1982]

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Conducting Sepsis Surveillance by Applying Sepsis-3 Criteria to Electronic Health Record Data: Promises and Potential Pitfalls.

Chanu Rhee, Michael Klompas,

Crit Care Med (Critical care medicine)
[2021, 49(11):1983-1986]

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The Evolution of Toolkits and Bundles to Improve the Care of Sepsis Patients.

Greg S Martin, Sandra L Kane-Gill, Vinay Nadkarni, Lauren R Sorce, Lewis J Kaplan, Maurizio Cecconi, Elie Azoulay, Jean-Louis Teboul, Lui Forni, Jozef Kesecioglu,

Crit Care Med (Critical care medicine)
[2021, 49(11):1849-1850]

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Accelerating Coronavirus Disease 2019 Therapeutic Interventions and Vaccines-Selecting Compounds for Clinical Evaluation in Coronavirus Disease 2019 Clinical Trials.

Timothy G Buchman, Ruxandra Draghia-Akli, Stacey J Adam, Neil R Aggarwal, Joshua P Fessel, Elizabeth S Higgs, Joseph P Menetski, Sarah W Read, Eric A Hughes, ,

Given the urgent need for coronavirus disease 2019 therapeutics, early in the pandemic the Accelerating Coronavirus Disease 2019 Therapeutic Interventions and Vaccines (ACTIV) public-private partnership rapidly designed a unique therapeutic agent intake and assessment process for candidate treatments of coronavirus disease 2019. These treatments included antivirals, immune modulators, severe acute ... Read more >>

Crit Care Med (Critical care medicine)
[2021, 49(11):1963-1973]

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Reflections on Critical Care's Past, Present, and Future.

Manu Shankar-Hari, Hannah Wunsch, Kathy Rowan, Mervyn Singer, Gordon D Rubenfeld, Derek C Angus,

Crit Care Med (Critical care medicine)
[2021, 49(11):1855-1865]

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Clinical Research: From Case Reports to International Multicenter Clinical Trials.

Simon Finfer, Deborah Cook, Flavia R Machado, Anders Perner,

Crit Care Med (Critical care medicine)
[2021, 49(11):1866-1882]

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The authors reply.

Suveer Singh, Diana A Gorog, Ciara F Mahon, Bhavin Rawal, Thomas R Semple, Edward D Nicol, Deepa R J Arachchillage, Susanna Price, Sujal Desai, Carole A Ridge, Simon P G Padley, Saeed Mirsadraee,

Crit Care Med (Critical care medicine)
[2021, 49(11):e1190-e1191]

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Temporal Trends in ICU Survival for Coronavirus Disease 2019: A Bumpy Road.

Hallie C Prescott, Mitchell M Levy,

Crit Care Med (Critical care medicine)
[2021, 49(11):1986-1988]

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Karuna Wongtangman, Matthias Eikermann,

Crit Care Med (Critical care medicine)
[2021, 49(11):e1188-e1189]

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Trends in 28-Day Mortality of Critical Care Patients With Coronavirus Disease 2019 in the United Kingdom: A National Cohort Study, March 2020 to January 2021.

John M Dennis, Andrew P McGovern, Nicholas J Thomas, Harrison Wilde, Sebastian J Vollmer, Bilal A Mateen,

<h4>Objectives</h4>To determine whether the previously described trend of improving mortality in people with coronavirus disease 2019 in critical care during the first wave was maintained, plateaued, or reversed during the second wave in United Kingdom, when B117 became the dominant strain.<h4>Design</h4>National retrospective cohort study.<h4>Setting</h4>All English hospital trusts (i.e., groups of ... Read more >>

Crit Care Med (Critical care medicine)
[2021, 49(11):1895-1900]

Cited: 1 time

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Reasons for the Overuse of Sedatives and Deep Sedation for Mechanically Ventilated Coronavirus Disease 2019 Patients.

Zhongxiang Xiao, Leping Zhao,

Crit Care Med (Critical care medicine)
[2021, 49(11):e1187-e1188]

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Endothelial Dysfunction as a Component of Severe Acute Respiratory Syndrome Coronavirus 2-Related Multisystem Inflammatory Syndrome in Children With Shock.

Delphine Borgel, Richard Chocron, Marion Grimaud, Aurélien Philippe, Judith Chareyre, Charlyne Brakta, Dominique Lasne, Damien Bonnet, Julie Toubiana, François Angoulvant, Maximilien Desvages, Sylvain Renolleau, David M Smadja, Mehdi Oualha,

<h4>Trial registration</h4>NCT04420468.<h4>Objectives</h4>Severe acute respiratory syndrome coronavirus 2-related multisystem inflammatory syndrome in children is frequently associated with shock; endothelial involvement may be one of the underlying mechanisms. We sought to describe endothelial dysfunction during multisystem inflammatory syndrome in children with shock and then assess the relationship between the degree of endothelial ... Read more >>

Crit Care Med (Critical care medicine)
[2021, 49(11):e1151-e1156]

Cited: 1 time

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Optimal Patient Selection for the Prophylactic Anticoagulation Therapy in Patients With Coronavirus Disease 2019.

Ayane Nishioka, Teruhiko Imamura,

Crit Care Med (Critical care medicine)
[2021, 49(11):e1182]

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Life-Threatening Bleeding in Children: A Prospective Observational Study.

Julie C Leonard, Cassandra D Josephson, James F Luther, Stephen R Wisniewski, Christine Allen, Fabrizio Chiusolo, Adrienne L Davis, Robert A Finkelstein, Julie C Fitzgerald, Barbara A Gaines, Susan M Goobie, Sheila J Hanson, Hilary A Hewes, Laurie H Johnson, Mark O McCollum, Jennifer A Muszynski, Alison B Nair, Robert B Rosenberg, Thomas M Rouse, Athina Sikavitsas, Marcy N Singleton, Marie E Steiner, Jeffrey S Upperman, Adam M Vogel, Hale Wills, Margaret K Winkler, Philip C Spinella,

<h4>Objectives</h4>The purpose of our study was to describe children with life-threatening bleeding.<h4>Design</h4>We conducted a prospective observational study of children with life-threatening bleeding events.<h4>Setting</h4>Twenty-four childrens hospitals in the United States, Canada, and Italy participated.<h4>Subjects</h4>Children 0-17 years old who received greater than 40 mL/kg total blood products over 6 hours or were transfused ... Read more >>

Crit Care Med (Critical care medicine)
[2021, 49(11):1943-1954]

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The Polio Ward at Rancho Los Amigos.

Richard D Branson,

Crit Care Med (Critical care medicine)
[2021, 49(11):e1193-e1194]

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Francesco Santoro, Ivan J Núñez-Gil, Natale Daniele Brunetti,

Crit Care Med (Critical care medicine)
[2021, 49(11):e1183-e1184]

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The authors reply.

Andrew A Kramer, Jack E Zimmerman, William A Knaus,

Crit Care Med (Critical care medicine)
[2021, 49(11):e1177]

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