Full Text Journal Articles in
Journal Crit Care Explor

Advertisement

Find full text journal articles






The Viral Infection and Respiratory Illness Universal Study (VIRUS): An International Registry of Coronavirus 2019-Related Critical Illness.

Allan J Walkey, Vishakha K Kumar, Michael O Harhay, Scott Bolesta, Vikas Bansal, Ognjen Gajic, Rahul Kashyap,

The coronavirus disease 2019 pandemic has disproportionally strained intensive care services worldwide. Large areas of uncertainly regarding epidemiology, physiology, practice patterns, and resource demands for patients with coronavirus disease 2019 require rapid collection and dissemination of data. We describe the conception and implementation of an intensive care database rapidly developed ... Read more >>

Crit Care Explor (Critical care explorations)
[2020, 2(4):e0113]

Cited: 0 times

View full text PDF listing >>



Timing of Onset, Burden, and Postdischarge Mortality of Persistent Critical Illness in Scotland, 2005-2014: A Retrospective, Population-Based, Observational Study.

Martin Shaw, Elizabeth M Viglianti, Joanne McPeake, Sean M Bagshaw, David Pilcher, Rinaldo Bellomo, Theodore J Iwashyna, Tara Quasim,

We aimed to understand the prevalence, timing of onset, resource use, and long-term outcomes of patients who developed persistent critical illness in a national dataset. Design:Retrospective cohort. Using a physiologic risk adjustment model from ICU admission, we examined the relative ability of acute (related to reason for ICU presentation) and ... Read more >>

Crit Care Explor (Critical care explorations)
[2020, 2(4):e0102]

Cited: 0 times

View full text PDF listing >>



Advertisement

Utilization of a Resuscitative Care Unit for Initial Triage, Management, and Disposition of Minor Intracranial Hemorrhage.

Jacob R Joseph, Nathan L Haas, John R Joseph, Jason Heth, Nicholas J Szerlip, Benjamin S Bassin,

Management of minor intracranial hemorrhage typically involves ICU admission. ICU capacity is increasingly strained, resulting in increased emergency department boarding of critically ill patients. Our objectives were to implement a novel protocol using our emergency department-based resuscitative care unit for management of management of minor intracranial hemorrhage patients in the ... Read more >>

Crit Care Explor (Critical care explorations)
[2020, 2(4):e0097]

Cited: 0 times

View full text PDF listing >>



Comparison of IV Insulin Dosing Strategies for Hyperkalemia in the Emergency Department.

Kayvan Moussavi, Lani T Nguyen, Henry Hua, Scott Fitter,

The objectives of this study were to evaluate the safety and efficacy of insulin dosing of less than 10 units versus 10 units in patients receiving hyperkalemia treatment. Design:Retrospective single-center study. Setting:Emergency department at a large academic medical center in the United States. Patients:Seven hundred adults treated for hyperkalemia with ... Read more >>

Crit Care Explor (Critical care explorations)
[2020, 2(4):e0092]

Cited: 0 times

View full text PDF listing >>



Rationale for Prolonged Corticosteroid Treatment in the Acute Respiratory Distress Syndrome Caused by Coronavirus Disease 2019.

Jesús Villar, Marco Confalonieri, Stephen M Pastores, G Umberto Meduri,

Crit Care Explor (Critical care explorations)
[2020, 2(4):e0111]

Cited: 0 times

View full text PDF listing >>



Temporary Transvenous Diaphragmatic Neurostimulation in Prolonged Mechanically Ventilated Patients: A Feasibility Trial (RESCUE 1).

Ali Ataya, Erin P Silverman, Aranya Bagchi, Aarti Sarwal, Gerard J Criner, David L McDonagh,

Prolonged mechanical ventilation promotes diaphragmatic atrophy and weaning difficulty. The study uses a novel device containing a transvenous phrenic nerve stimulating catheter (Lungpacer IntraVenous Electrode Catheter) to stimulate the diaphragm in ventilated patients. We set out to determine the feasibility of temporary transvenous diaphragmatic neurostimulation using this device. Design:Multicenter, prospective ... Read more >>

Crit Care Explor (Critical care explorations)
[2020, 2(4):e0106]

Cited: 0 times

View full text PDF listing >>



Procedures Performed by Advanced Practice Providers Compared With Medical Residents in the ICU: A Prospective Observational Study.

Herman G Kreeftenberg, Jeroen T Aarts, Alexander J G H Bindels, Nardo J M van der Meer, Peter H J van der Voort,

To assess the frequency and safety of procedures performed by advanced practice providers and medical residents in a mixed-bed ICU. Design:A prospective observational study where consecutive invasive procedures were studied over a period of 1 year and 8 months. The interventions were registered anonymously in an online database. Endpoints were ... Read more >>

Crit Care Explor (Critical care explorations)
[2020, 2(4):e0101]

Cited: 0 times

View full text PDF listing >>



Effect of Very Low-Dose Hydrocortisone on Shock Reversal in Patients With Septic Shock.

Robert Sbertoli, Zeyu Hu, Jonathan Henke, Eric Wu, Shrihari Santosh, Stephen Osmon, Edward Charbek, Zafar Jamkhana, Sadashiv Santosh,

In patients with septic shock, hydrocortisone 200-400 mg/d has been shown to reverse shock compared with placebo. Lower doses of hydrocortisone have not previously been studied, and there are no previous studies comparing two different doses of hydrocortisone. At our institution, some clinicians routinely prescribe doses less than 200 mg/d. This study ... Read more >>

Crit Care Explor (Critical care explorations)
[2020, 2(4):e0096]

Cited: 0 times

View full text PDF listing >>



Quantifying Mobility in the ICU: Comparison of Electronic Health Record Documentation and Accelerometer-Based Sensors to Clinician-Annotated Video.

Sarina Fazio, Amy Doroy, Natalie Da Marto, Sandra Taylor, Nicholas Anderson, Heather M Young, Jason Y Adams,

To compare the accuracy of electronic health record clinician documentation and accelerometer-based sensors with a gold standard dataset derived from clinician-annotated video to quantify early mobility activities in adult ICU patients. Design:Prospective, observational study. Setting:Medical ICU at an academic hospital. Patients:Adult ICU patients (n = 30) were each continuously monitored ... Read more >>

Crit Care Explor (Critical care explorations)
[2020, 2(4):e0091]

Cited: 0 times

View full text PDF listing >>



The Clinical Presentation and Immunology of Viral Pneumonia and Implications for Management of Coronavirus Disease 2019.

Dijoia B Darden, Russell B Hawkins, Shawn D Larson, Nicole M Iovine, Donald S Prough, Philip A Efron,

This review will briefly examine the clinical presentation and important immunology of viral pneumonia with a focus on severe acute respiratory syndrome coronavirus 2 (coronavirus disease 2019). Data Sources Study Selection Data Extraction and Data Synthesis:The most relevant, original and review literature were assessed for inclusion in this review. Sources ... Read more >>

Crit Care Explor (Critical care explorations)
[2020, 2(4):e0109]

Cited: 0 times

View full text PDF listing >>



Assessing the Course of Organ Dysfunction Using Joint Longitudinal and Time-to-Event Modeling in the Vasopressin and Septic Shock Trial.

Michael O Harhay, Alessandro Gasparini, Allan J Walkey, Gary E Weissman, Michael J Crowther, Sarah J Ratcliffe, James A Russell,

Non-mortality septic shock outcomes (e.g., Sequential Organ Failure Assessment score) are important clinical endpoints in pivotal sepsis trials. However, comparisons of observed longitudinal non-mortality outcomes between study groups can be biased if death is unequal between study groups or is associated with an intervention (i.e., informative censoring). We compared the ... Read more >>

Crit Care Explor (Critical care explorations)
[2020, 2(4):e0104]

Cited: 0 times

View full text PDF listing >>



Using the Surviving Sepsis Coronavirus Disease 2019 Guidelines-Anything New Yet?

Ramzy H Rimawi,

Crit Care Explor (Critical care explorations)
[2020, 2(4):e0099]

Cited: 0 times

View full text PDF listing >>



The Efficacy, Safety, and Optimal Regimen of Corticosteroids in Sepsis: A Bayesian Network Meta-Analysis.

Shi Zhang, Wei Chang, Jianfeng Xie, Zongsheng Wu, Yi Yang, Haibo Qiu,

Conventional systematic reviews have indicated that corticosteroids might result in a slight reduction in mortality in sepsis. However, the efficacy, safety, and optimal regimen of different corticosteroids partly remain unknown. In this study, we conducted a Bayesian network meta-analysis for a head-to-head comparison of the therapeutic efficacy and safety of ... Read more >>

Crit Care Explor (Critical care explorations)
[2020, 2(4):e0094]

Cited: 0 times

View full text PDF listing >>



Opioid and Benzodiazepine Withdrawal Syndromes in Trauma ICU Patients: A Prospective Exploratory Study.

Carmen Mabel Arroyo-Novoa, Milagros I Figueroa-Ramos, Michele Balas, Pablo Rodríguez, Kathleen A Puntillo,

Trauma ICU patients may require high and/or prolonged doses of opioids and/or benzodiazepines as part of their treatment. These medications may contribute to drug physical dependence, a response manifested by withdrawal syndrome. We aimed to identify risk factors, symptoms, and clinical variables associated with probable withdrawal syndrome. Design:Prospective exploratory observational ... Read more >>

Crit Care Explor (Critical care explorations)
[2020, 2(4):e0089]

Cited: 0 times

View full text PDF listing >>



A Conceptual and Adaptable Approach to Hospital Preparedness for Acute Surge Events Due to Emerging Infectious Diseases.

George L Anesi, Ylinne Lynch, Laura Evans,

At the time this article was written, the World Health Organization had declared a global pandemic due to the novel coronavirus disease 2019, the first pandemic since 2009 H1N1 influenza A. Emerging respiratory pathogens are a common trigger of acute surge events-the extreme end of the healthcare capacity strain spectrum ... Read more >>

Crit Care Explor (Critical care explorations)
[2020, 2(4):e0110]

Cited: 0 times

View full text PDF listing >>



Potential Neurodevelopmental Effects of Pediatric Intensive Care Sedation and Analgesia: Repetitive Benzodiazepine and Opioid Exposure Alters Expression of Glial and Synaptic Proteins in Juvenile Rats.

Alia Marie Iqbal O'Meara, Nikki Miller Ferguson, Sidney E Zven, Oliver L Karam, Logan C Meyer, John W Bigbee, Carmen Sato-Bigbee,

Sedatives are suspected contributors to neurologic dysfunction in PICU patients, to whom they are administered during sensitive neurodevelopment. Relevant preclinical modeling has largely used comparatively brief anesthesia in infant age-approximate animals, with insufficient study of repetitive combined drug administration during childhood. We hypothesized that childhood neurodevelopment is selectively vulnerable to ... Read more >>

Crit Care Explor (Critical care explorations)
[2020, 2(4):e0105]

Cited: 0 times

View full text PDF listing >>



Evaluation of Sedation Outcomes Following Increased Dexmedetomidine Use in the ICU.

Brian R Schuler, Mary P Kovacevic, Kevin M Dube, Paul M Szumita, Jeremy R DeGrado,

To evaluate sedation practices following a dexmedetomidine guideline update in the ICU. Design:Single-center, retrospective chart review. Setting:Tertiary academic medical center. Patients:Patients were included in this analysis if they were admitted to the ICU and were ordered for continuous infusion sedatives or opioids from September to November 2016 (PRE) and from ... Read more >>

Crit Care Explor (Critical care explorations)
[2020, 2(4):e0100]

Cited: 0 times

View full text PDF listing >>



Estimation and Tracking of Blood Pressure Using Routinely Acquired Photoplethysmographic Signals and Deep Neural Networks.

Oded Schlesinger, Nitai Vigderhouse, Yair Moshe, Danny Eytan,

Continuous tracking of blood pressure in critically ill patients allows rapid identification of clinically important changes and helps guide treatment. Classically, such tracking requires invasive monitoring with its associated risks, discomfort, and low availability outside critical care units. We hypothesized that information contained in a prevalent noninvasively acquired signal (photoplethysmograph: ... Read more >>

Crit Care Explor (Critical care explorations)
[2020, 2(4):e0095]

Cited: 0 times

View full text PDF listing >>



Early Mobilization in the ICU: A Collaborative, Integrated Approach.

Christopher A Linke, Leah B Chapman, Lindsey J Berger, Tara L Kelly, Craig A Korpela, Michael G Petty,

To develop and implement a protocol to increase patient mobility in three adult ICUs using an interdisciplinary approach and existing resources. Design:The Iowa Model of Evidence-Based Practice was used for synthesis of literature and intervention planning. A retrospective pre- and post-intervention data collection design was used to compare outcomes of ... Read more >>

Crit Care Explor (Critical care explorations)
[2020, 2(4):e0090]

Cited: 0 times

View full text PDF listing >>



Clinical Distancing and Mitigation of Coronavirus Disease 2019.

Benjamin K Scott, Marilyn Hravnak, Jeremy C Pamplin,

Social distancing as a technique to limit transmission of infectious disease has come into common parlance following the arrival and rapid spread of a novel coronavirus disease around the world in 2019 and 2020. But in the face of an emerging pandemic threat, it is crucial that we start to ... Read more >>

Crit Care Explor (Critical care explorations)
[2020, 2(4):e0117]

Cited: 0 times

View full text PDF listing >>



Fact Versus Science Fiction: Fighting Coronavirus Disease 2019 Requires the Wisdom to Know the Difference.

Nicholas E Ingraham, Christopher J Tignanelli,

Crit Care Explor (Critical care explorations)
[2020, 2(4):e0108]

Cited: 0 times

View full text PDF listing >>



Increased Inpatient Length of Stay After Early Unplanned Transfer to Higher Levels of Care.

Daniel Sykora, Stephen J Traub, Matthew R Buras, Nicole R Hodgson, Holly L Geyer,

Patients admitted to a medical-surgical unit infrequently require early transfer to higher level care, although how their inpatient length of stay compares to untransferred patients, or those directly admitted to intermediate care, is unknown. We sought to compare the inpatient length of stay of these groups. Design:Single-site retrospective analysis. Setting:An ... Read more >>

Crit Care Explor (Critical care explorations)
[2020, 2(4):e0103]

Cited: 0 times

View full text PDF listing >>



Misinformation During the Coronavirus Disease 2019 Outbreak: How Knowledge Emerges From Noise.

Bram Rochwerg, Rachael Parke, Srinivas Murthy, Shannon M Fernando, Jeanna Parsons Leigh, John Marshall, Neill K J Adhikari, Kirsten Fiest, Rob Fowler, François Lamontagne, Jonathan E Sevransky,

Although the amount of information generated during this most recent coronavirus disease 2019 pandemic is enormous, much is of uncertain trustworthiness. This review summaries the many potential sources of information that clinicians turn to during pandemic illness, the challenges associated with performing methodologically sound research in this setting and potential ... Read more >>

Crit Care Explor (Critical care explorations)
[2020, 2(4):e0098]

Cited: 0 times

View full text PDF listing >>



Extracorporeal Membrane Oxygenation as a Bridge to Chimeric Antigen Receptor T-cell Therapy for Severe Refractory Sepsis in the Setting of Relapsed Refractory Pediatric Acute Lymphoblastic Leukemia: A Case Report.

Alyssa Stoner, Jenna O Miller, Terrie Flatt, Jessica S Wallisch,

Pediatric oncology patients with sepsis are at higher risk of morbidity and mortality compared with pediatric patients without malignancy. Historically, patients with relapsed and/or refractory disease were not considered candidates for aggressive life support strategies including extracorporeal membrane oxygenation support. Case Summary:We report a 4-year-old female with relapsed refractory pre-B ... Read more >>

Crit Care Explor (Critical care explorations)
[2020, 2(4):e0093]

Cited: 0 times

View full text PDF listing >>



Key Components of ICU Recovery Programs: What Did Patients Report Provided Benefit?

Joanne McPeake, Leanne M Boehm, Elizabeth Hibbert, Rita N Bakhru, Anthony J Bastin, Brad W Butcher, Tammy L Eaton, Wendy Harris, Aluko A Hope, James Jackson, Annie Johnson, Janet A Kloos, Karen A Korzick, Pamela MacTavish, Joel Meyer, Ashley Montgomery-Yates, Tara Quasim, Andrew Slack, Dorothy Wade, Mary Still, Giora Netzer, Ramona O Hopkins, Mark E Mikkelsen, Theodore J Iwashyna, Kimberley J Haines, Carla M Sevin,

To understand from the perspective of patients who did, and did not attend ICU recovery programs, what were the most important components of successful programs and how should they be organized. Design:International, qualitative study. Setting:Fourteen hospitals in the United States, United Kingdom, and Australia. Patients:We conducted 66 semi-structured interviews with ... Read more >>

Crit Care Explor (Critical care explorations)
[2020, 2(4):e0088]

Cited: 0 times

View full text PDF listing >>



Advertisement

Disclaimer
0.9686 s