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Journal Clin Oral Investig

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Correction to: Class II resin composite restorations-tunnel vs. box-only in vitro and in vivo.

Peter J Preusse, Julia Winter, Stefanie Amend, Matthias J Roggendorf, Marie-Christine Dudek, Norbert Krämer, Roland Frankenberger,

Clin Oral Investig (Clinical oral investigations)
[2021, 25(10):6025]

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Gingival recession treatment with enamel matrix derivative associated with coronally advanced flap and subepithelial connective tissue graft: a split-mouth randomized controlled clinical trial with molecular evaluation.

Alexandra Tavares Dias, Claudia Callegaro de Menezes, Sergio Kahn, Ricardo Guimarães Fischer, Carlos Marcelo da Silva Figueredo, Gustavo Vicentis de Oliveira Fernandes,

<h4>Objectives</h4>The goal of this study was to evaluate the impact of enamel matrix derivative (EMD) on periodontal healing after root coverage (RC) surgery, involving CAF in combination with SCTG, and to assess the molecular profile, verifying the inflammation level in early stage (1 and 2 weeks).<h4>Materials and methods</h4>Thirty-two recessions (RT1) were ... Read more >>

Clin Oral Investig (Clinical oral investigations)
[2021, :]

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Relationship between anterior maxillary tooth sagittal root position and periodontal phenotype: a clinical and tomographic study.

Diogo M Rodrigues, Rodrigo L Petersen, Caroline Montez, José R de Moraes, Alessandro L Januário, Eliane P Barboza,

<h4>Objectives</h4>To evaluate the relationship between the tomographic sagittal root position (SRP) of maxillary anterior teeth and periodontal phenotype (PP).<h4>Material and methods</h4>Seventy volunteers (420 teeth) were evaluated. Clinical and photographic exams included the evaluation of gingival phenotype (GP) by transparency of the periodontal probe, keratinized tissue width (KTW), gingival architecture, tooth ... Read more >>

Clin Oral Investig (Clinical oral investigations)
[2021, :]

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Efficacy of hyaluronic acid for recurrent aphthous stomatitis: a systematic review of clinical trials.

Sadeq Ali Al-Maweri, Nader Alaizari, Rawan Hejji Alanazi, Sajna Ashraf, Rania Hejji Alanazi, Hesham Mohammed Al-Sharani, Esam Halboub,

<h4>Objectives</h4>Recurrent aphthous stomatitis (RAS) is a very common oral mucosal disease, and its management is quite challenging with no definitive cure being available so far. Many studies have tried hyaluronic acid (HA) for alleviating signs and symptoms of RAS. The present systematic review sought to assess the available evidence regarding ... Read more >>

Clin Oral Investig (Clinical oral investigations)
[2021, :]

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Bacterial colonisation during regular daily use of a power-driven water flosser and risk for cross-contamination. Can it be prevented?

Kristina Bertl, Chiarra Geissberger, David Zinndorf, Pia Edlund Johansson, Hatem Al-Shammari, Sigrun Eick, Andreas Stavropoulos,

<h4>Objective</h4>To assess whether bacterial colonisation in a power-driven water flosser can be prevented.<h4>Materials and methods</h4>Twenty-four patients undergoing supportive periodontal treatment used 2 power-driven water flossers [Sonicare AirFloss (SAF), AirFloss Ultra (SAFU)] for 12 weeks each as follows: (a) with bottled water (BW); (b) with BW and cleaning the device extra-orally twice ... Read more >>

Clin Oral Investig (Clinical oral investigations)
[2021, :]

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Correction to: Early bone formation around immediately loaded implants with nanostructured calcium-incorporated and machined surface: a randomized, controlled histologic and histomorphometric study in the human posterior maxilla.

Francesco Guido Mangano, Giovanna Iezzi, Jamil Awad Shibli, Jefferson Trabach Pires, Giuseppe Luongo, Adriano Piattelli, Carlo Mangano,

Clin Oral Investig (Clinical oral investigations)
[2021, :]

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Phosphorylated PAMAM dendrimers: an analog of dentin non-collagenous proteins, enhancing the osteo/odontogenic differentiation of dental pulp stem cells.

Jie Liu, Yuan Gao, Xiaodong Zhu, Yuerong Zhang, Hai Xu, Tianda Wang, Guangdong Zhang,

<h4>Objectives</h4>Polyamidoamine (PAMAM) dendrimers have well-defined structures, with monodispersity and easily modified surface groups, and they have broad applications in biomedicine. In this study, phosphorylated PAMAM (P-PAMAM) dendrimers were synthesized based on the idea of mimicking the phosphorylated proteins of dentin non-collagenous proteins (DNCP). Then, proliferation and osteo/odontogenic differentiation effects of ... Read more >>

Clin Oral Investig (Clinical oral investigations)
[2021, :]

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Enamel erosion control by strontium-containing TiO2- and/or MgO-doped phosphate bioactive glass.

Berthyelle Pádova Nyland, Cristiano Porcel Pereira, Paulo Soares, Denise Stolle da Luz Weiss, Walter Luís Mikos, João Armando Brancher, Sérgio Vieira, Andrea Freire,

<h4>Objectives</h4>To evaluate the effect of strontium-containing titanium- and/or magnesium-doped phosphate bioactive glass on the control of dental erosion.<h4>Materials and methods</h4>Fifty fragments of human enamel were divided into five groups: negative control, 45S5 bioglass, strontium-containing Ti-doped phosphate bioactive glass (PBG-Ti), strontium-containing Mg-doped phosphate bioactive glass (PBG-Mg), and strontium-containing Ti- and Mg-doped ... Read more >>

Clin Oral Investig (Clinical oral investigations)
[2021, :]

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Prevalence of red and orange microbial complexes in endodontic-periodontal lesions: a systematic review and meta-analysis.

Diego José Gambin, Filipe Colombo Vitali, João Paulo De Carli, Ricardo Ruiz Mazzon, Brenda P F A Gomes, Thais Mageste Duque, Micheline Sandini Trentin,

<h4>Objective</h4>This systematic review assesses the prevalence of microbial complexes in endodontic-periodontal lesion.<h4>Materials and methods</h4>Nine databases were searched through August 2020. Experts were consulted to indicate additional studies. Studies were blindly selected by two reviewers based on pre-defined eligibility criteria. Studies that evaluated the prevalence of microbial orange and red complexes ... Read more >>

Clin Oral Investig (Clinical oral investigations)
[2021, :]

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Clinical study comparing the accuracy of interocclusal records, digitally obtained by three different devices.

Cristina Fraile, Alberto Ferreiroa, Marta Romeo, Raquel Alonso, Guillermo Pradíes,

<h4>Objective</h4>The aim of the present cross-sectional study was to compare the interocclusal contact records obtained by three different digital methods (intra- and extraoral digital scanners and T-Scan III system) with the conventional method (articulating paper).<h4>Materials and methods</h4>Twenty-five healthy volunteers were selected. As a control group, maximum intercuspation occlusal contacts were ... Read more >>

Clin Oral Investig (Clinical oral investigations)
[2021, :]

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Assessment of bone metabolism biomarkers in serum and saliva of cirrhotic patients.

Jefferson Rocha Tenório, Nathália Tuany Duarte, Natália Silva Andrade, Mariana Lobo Bergamini, Ana Carolina Mamana, Paulo Henrique Braz-Silva, Karem L Ortega,

<h4>Objective</h4>To assess the serum and salivary levels of biomarkers related to bone metabolism in cirrhotic patients as well as the evidence of osteoporotic changes on panoramic radiographs.<h4>Materials and methods</h4>Thirty-eight cirrhotic patients underwent anamnesis and physical examination. Specimens of blood and saliva were collected for evaluation by using Luminex™ xMAP technology ... Read more >>

Clin Oral Investig (Clinical oral investigations)
[2021, :]

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Effect of micro-osteoperforations on the gene expression profile of the periodontal ligament of orthodontically moved human teeth.

Alice Spitz, Daniel Adesse, Michael Gonzalez, Renata Pellegrino, Hakon Hakonarson, Guido Artemio Marañón-Vásquez, Ana Maria Bolognese, Flavia Teles,

<h4>Objectives</h4>This study aimed to evaluate the effect of micro-osteoperforations (MOPs) on the gene expression profile of the periodontal ligament (PDL) of orthodontically moved teeth.<h4>Materials and methods</h4>Fifteen participants were randomly assigned into two groups: tooth movement only (Tr1, n = 7) and tooth movement supplemented with MOPs (Tr2, n = 8). In each subject, orthodontic ... Read more >>

Clin Oral Investig (Clinical oral investigations)
[2021, :]

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Intraoral scanner-based monitoring of tooth wear in young adults: 12-month results.

Maximiliane Amelie Schlenz, Moritz Benedikt Schlenz, Bernd Wöstmann, Alexandra Jungert, Carolina Ganss,

<h4>Objectives</h4>To investigate tooth wear in young adults, intraoral scanning was used for digital monitoring of the mandibular first molar over 12 months. A possible influence of aetiological factors obtained by a questionnaire on tooth wear was investigated.<h4>Materials and methods</h4>A total of 109 participants (mean age at the start of the study: ... Read more >>

Clin Oral Investig (Clinical oral investigations)
[2021, :]

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The role of surgical flap design (minimally invasive flap vs. extended flap with papilla preservation) on the healing of intrabony defects treated with an enamel matrix derivative: a 12-month two-center randomized controlled clinical trial.

Peter Windisch, Vincenzo Iorio-Siciliano, Daniel Palkovics, Luca Ramaglia, Andrea Blasi, Anton Sculean,

<h4>Objectives</h4>Minimally invasive flap designs have been introduced to enhance blood clot stability and support wound healing. Limited data appear to suggest, that in intrabony defects, better clinical outcomes can be achieved by means of minimally invasive flap compared to more extended flaps. The aim of this study was to evaluate ... Read more >>

Clin Oral Investig (Clinical oral investigations)
[2021, :]

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Three-dimensional volumetric evaluation of dental pulp cavity/tooth ratio in anterior open bite malocclusion using cone beam computed tomography.

Kachaphol Kuharattanachai, Dhirawat Jotikasthira, Supassara Sirabanchongkran, Tanida Srisuwan, Wetchayan Rangsri, Kanich Tripuwabhrut,

<h4>Objectives</h4>To assess and compare pulp cavity/tooth volume ratio of maxillary permanent teeth between patients exhibiting anterior open bite malocclusion and those exhibiting anterior normal overbite using cone beam computed tomography (CBCT).<h4>Materials and methods</h4>3D dental images from 44 patients aged between 15 and 29 years were analyzed. The DICOM files of all ... Read more >>

Clin Oral Investig (Clinical oral investigations)
[2021, :]

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Systematic review and meta-analysis of diagnostic studies of proximal surface caries.

Mila Janjic Rankovic, Svetlana Kapor, Yegane Khazaei, Alexander Crispin, Ina Schüler, Felix Krause, Kim Ekstrand, Stavroula Michou, Florin Eggmann, Adrian Lussi, Marie-Charlotte Huysmans, Klaus Neuhaus, Jan Kühnisch,

<h4>Aim</h4>This systematic review and meta-analysis aimed to assess the diagnostic accuracy and reliability of commonly used caries detection methods for proximal caries diagnostics. Visual examination (VE), bitewing radiography (BWR), laser fluorescence (LF), and fibre-optic transillumination (FOTI) were considered in detail.<h4>Material and methods</h4>PRISMA guidelines for the reporting of systematic reviews and ... Read more >>

Clin Oral Investig (Clinical oral investigations)
[2021, :]

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Early failures when using three different adhesively retained core build-up materials-a randomized controlled trial.

Andreas Zenthöfer, Justo Lorenzo Bermejo, Wolfgang Bömicke, Cornelia Frese, Rumeysa Gülmez, Peter Rammelsberg, Brigitte Ohlmann,

<h4>Objectives</h4>To compare the failure rates for three different adhesively retained core build-up composites up to the incorporation of a permanent fixed dental prosthesis (FDP), and to identify potential failure risk factors.<h4>Material and methods</h4>A randomized controlled trial of 300 participants in need of a core build-up to restore a vital abutment ... Read more >>

Clin Oral Investig (Clinical oral investigations)
[2021, :]

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Two-year randomized clinical trial of different restorative techniques in non-carious cervical lesions and MMP activity in gingival crevicular fluid.

Rafael Simões Gonçalves, Polliana Mendes Candia Scaffa, Mirela Sanae Shinohara, Paulo Roberto Marão de Andrade Carvalho, Marília Afonso Rabelo Buzalaf, Ticiane Cestari Fagundes,

<h4>Objectives</h4>To evaluate different restorative techniques for non-carious cervical lesions (NCCLs) and the activity of matrix metalloproteinases (MMPs) in gingival crevicular fluid.<h4>Materials and methods</h4>Two hundred restorations were performed in 50 patients using resin composite restorative system without (I) and with selective enamel conditioning (II) and resin-modified glass-ionomer cement without (III) and ... Read more >>

Clin Oral Investig (Clinical oral investigations)
[2021, :]

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Influence of the activation mode on long-term bond strength and endogenous enzymatic activity of dual-cure resin cements.

Claudia Mazzitelli, Tatjana Maravic, Edoardo Mancuso, Uros Josic, Luigi Generali, Allegra Comba, Annalisa Mazzoni, Lorenzo Breschi,

<h4>Objective</h4>To investigate the long-term microtensile bond strength (µTBS), interfacial nanoleakage expression (NL), and adhesive stability of dual-cure resin cements with/out light activation to dentin.<h4>Materials and methods</h4>Composite overlays (N = 20) were luted to deep dentin surfaces with RelyX Ultimate (RXU, 3M) or Variolink EstheticDC (VAR, Ivoclar-Vivadent). A universal adhesive was used for ... Read more >>

Clin Oral Investig (Clinical oral investigations)
[2021, :]

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The effect of changing apical foramen diameter on regenerative potential of mature teeth with necrotic pulp and apical periodontitis.

Hisham M Abada, Ahmed Abdel Rahman Hashem, Ashraf Mohamed Abu-Seida, Mohamed Mokhtar Nagy,

<h4>Objective</h4>The aim of the present study was to evaluate the regenerative potential of permanent necrotic mature teeth with different apical foramen diameters in comparison to conventional endodontic treatment.<h4>Methods</h4>Pulp necrosis and periapical pathosis were induced in premolars (144 roots) in six mongrel dogs. The infected teeth were divided into six groups; ... Read more >>

Clin Oral Investig (Clinical oral investigations)
[2021, :]

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Hypersensitivity relief of MIH-affected molars using two sealing techniques: a 12-week follow-up.

Katrin Bekes, Stefanie Amend, Julia Priller, Claudia Zamek, Tanja Stamm, Norbert Krämer,

<h4>Objectives</h4>The aim of this study was to compare the efficacy in reducing hypersensitivity in molar incisor hypomineralization (MIH)-affected molars immediately and over 12 weeks after sealing using two different materials (composite and glass ionomer). Furthermore, the retention rates of both materials were analyzed.<h4>Methods</h4>Thirty-nine children with two MIH-affected molars showing hypersensitivity ... Read more >>

Clin Oral Investig (Clinical oral investigations)
[2021, :]

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Correction to: Cellular effects of glycine and trehalose air‑polishing powders on human gingival fibroblasts in vitro.

Jens Weusmann, James Deschner, Jean-Claude Imber, Anna Damanaki, Natalia D P Leguizamón, Andressa V B Nogueira,

Clin Oral Investig (Clinical oral investigations)
[2021, :]

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Quantitative sensory testing in patients with the muscle pain subtype of temporomandibular disorder: a systemic review and meta-analysis.

He Meng, Juan Dai, Yuzhou Li,

<h4>Objectives</h4>This meta-analysis aimed to evaluate quantitative sensory testing (QST) evidence for pain processing in patients with the muscle pain subtype of temporomandibular disorders (mTMD).<h4>Materials and methods</h4>A comprehensive systematic electronic search strategy was performed in online literature databases. All full-text observational studies published up to July 2021 with the aim of ... Read more >>

Clin Oral Investig (Clinical oral investigations)
[2021, :]

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Correction to: Temporary materials: comparison of in vivo and in vitro performance.

Tuğrul Sari, Aslihan Usumez, Thomas Strasser, Abdurrahman Şahinbas, Martin Rosentritt,

A Correction to this paper has been published: https://doi.org/10.1007/s00784-021-04067-4. ... Read more >>

Clin Oral Investig (Clinical oral investigations)
[2021, 25(9):5577]

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Effect of precooling injection site and cold anesthetic administration on injection pain, onset, and anesthetic efficacy in maxillary molars with symptomatic irreversible pulpitis: a randomized controlled trial.

Ishwarya Gurucharan, Mahalaxmi Sekar, Saravanakarthikeyan Balasubramanian, Srinivasan Narasimhan,

<h4>Objective</h4>This randomized controlled clinical trial assessed the analgesic and anesthetic effects of precooling the injection site and administration of refrigerated 2% lignocaine HCl with 1:100,000 epinephrine (LE) in maxillary molars with symptomatic irreversible pulpitis (SIP).<h4>Materials and methods</h4>Sixty patients diagnosed with SIP (preoperative pain score ≥ 85 mm) in maxillary first molars were randomly ... Read more >>

Clin Oral Investig (Clinical oral investigations)
[2021, :]

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