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Journal Clin J Pain

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Changes in Pain Sensitivity and Conditioned Pain Modulation During Recovery from Whiplash Associated Disorders.

Steffan Wittrup McPhee Christensen, Pablo Bellosta-López, Víctor Doménech-García, Pablo Herrero, Thorvaldur Skuli Palsson,

<h4>Objectives</h4>To investigate the pain-sensory profile of patients with whiplash-associated disorders (WAD) prior and post 2-weeks of standardized rehabilitation and after at 6-months follow-up.<h4>Methods</h4>Twenty-two WAD-participants (Grade-II; 14 women) and 22 sex-and age-matched healthy controls were enrolled. Pressure pain thresholds (PPTs) were assessed at local and distal muscles. Conditioned pain modulation (CPM) ... Read more >>

Clin J Pain (The Clinical journal of pain)
[2021, :]

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The Use of Magnesium Sulfate and Peripheral Nerve Blocks: An Updated Meta-analysis and Systematic Review.

Jie Zeng, Qi Chen, Cong Yu, Ju Zhou, Bin Yang,

<h4>Objectives</h4>With the popularization of ultrasound, nerve blocks have been widely implemented in current clinical practice. Although, they have seen limited success due to their shorter duration and suboptimal analgesia. Magnesium sulfate as a local anesthetic adjuvant for peripheral nerve blocks could enhance the effects of local anesthetics. However, previous investigations ... Read more >>

Clin J Pain (The Clinical journal of pain)
[2021, 37(8):629-637]

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Reassuring Patients With Low Back Pain in Primary Care Consultations: Does it Happen, and Does it Matter? A ChiCo Cohort Study.

Gitte D Simonsen, Tue S Jensen, Alice Kongsted,

<h4>Objectives</h4>Reassurance is an important part of treatment for low back pain (LBP). The Consultation-based Reassurance Questionnaire measures patients' perceived reassurance after health care consultations on 4 subdomains (ie, Data-gathering, Relationship-building, Generic reassurance, Cognitive reassurance). The objectives of this study were to investigate associations between the level of reassurance and outcomes ... Read more >>

Clin J Pain (The Clinical journal of pain)
[2021, 37(8):598-606]

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Perceived Injustice Is Associated With Pain-related Function and Mood in Youth With Acute Musculoskeletal Pain.

Eleanor A J Battison, Anna C Wilson, Amy L Holley,

<h4>Objectives</h4>Perceived injustice (PI), which is one's appraisal of justice or fairness regarding the pain experience, is an emerging area of interest in pediatric pain research. No previous studies have investigated PI in youth with acute pain. To fill this gap, this study examined (1) associations among PI, pain-related function, and ... Read more >>

Clin J Pain (The Clinical journal of pain)
[2021, 37(8):575-582]

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Comparison of the Analgesic Effects of Intravenous Infusion of Dexmedetomidine Versus Bilateral Superficial Cervical Plexus Block After Thyroidectomy: A Randomized Controlled Trial.

Jibin Xing, Ranliang Wu, Ling Liang, Hongyi Fang, Liubing Chen, Chenfang Luo,

<h4>Objectives</h4>Dexmedetomidine (DEX) is widely used in clinical practice because of its safety and effectiveness. Superficial cervical plexus block (SCPB) can reduce pain in thyroid surgery. The objective of this study was to investigated whether intravenous DEX has an equivalent analgesic effect and patients' satisfaction to SCPB for thyroid surgery.<h4>Materials and ... Read more >>

Clin J Pain (The Clinical journal of pain)
[2021, 37(8):623-628]

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A Commentary on "Transmuscular Quadratus Lumborum and Lateral Femoral Cutaneous Nerve Block in Total Hip Arthroplasty".

Yali Wu, Jian Hu, Min Xu, Jing Yang,

Clin J Pain (The Clinical journal of pain)
[2021, :]

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Heart Rate Variability and Pain Sensitivity in Chronic Low Back Pain Patients Exposed to Passive Viewing of Photographs of Daily Activities.

Pâmela M Bandeira, Felipe J J Reis, Fernanda D N Muniz, Anna C S Chaves, Orlando Fernandes, Tiago Arruda-Sanchez,

<h4>Objective</h4>Investigation if emotional reactivity by measuring heart rate variability (HRV) and pressure pain sensitivity during a passive visualization task in participants with chronic low back pain (CLBP).<h4>Materials and methods</h4>This case-control study was composed of 47 participants with CLBP and 47 asymptomatic participants. Both groups were submitted to a passive visualization ... Read more >>

Clin J Pain (The Clinical journal of pain)
[2021, 37(8):591-597]

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Behavioral Test (BAT-Back): Preliminary Evidence for a Successful Predictor of Treatment Outcome After Exposure Treatment for Chronic Low Back Pain.

Mark J Hancock, Peter Kent, Anne Smith,

Clin J Pain (The Clinical journal of pain)
[2021, 37(8):638]

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The Effect of Preoperative Serratus Anterior Muscle Plane Block on Persistent Postsurgical Pain After Video-assisted Thoracic Surgery: A Retrospective Cohort Study.

Hong Zhao, Yaqing Wu, Xizhe Zhang, Yi Feng,

<h4>Objectives</h4>Acute pain intensity is a strong indicator for the occurrence of persistent postsurgical pain (PPP) after video-assisted thoracic surgery (VATS). The effect of preoperative Serratus Anterior Muscle Plane Block (SAPB) on PPP was investigated.<h4>Methods</h4>In this retrospective cohort study, data of 148 patients who underwent VATS for lung nodules in 2019 ... Read more >>

Clin J Pain (The Clinical journal of pain)
[2021, :]

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Inches, Centimeters, and Yards: Overlooked Definition Choices Inhibit Interpretation of Morphine Equivalence.

Nabarun Dasgupta, Yanning Wang, Jungjun Bae, Alan C Kinlaw, Brooke A Chidgey, Toska Cooper, Chris Delcher,

<h4>Objective</h4>Morphine-standardized doses are used in clinical practice and research to account for molecular potency. Ninety milligrams of morphine equivalents (MME) per day are considered a "high dose" risk threshold in guidelines, laws, and by payers. Although ubiquitously cited, the "CDC definition" of daily MME lacks a clearly defined denominator. Our ... Read more >>

Clin J Pain (The Clinical journal of pain)
[2021, 37(8):565-574]

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The Utility of an Anxiety Screening Measure in Youth With Functional Abdominal Pain Disorders and Clinical Characteristics Associated With Presence of Anxiety.

Richa Aggarwal Dutta, Samantha L Ely, Natoshia R Cunningham,

<h4>Objectives</h4>Anxiety is common in youth with functional abdominal pain disorders (FAPD) and is related to increased pain-related impairment. However, it is unknown if self-reported anxiety on a clinical screener represents a true anxiety disorder diagnosis in youth with FAPD. Further, little is known about clinical characteristics in youth with FAPD ... Read more >>

Clin J Pain (The Clinical journal of pain)
[2021, 37(8):616-622]

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Impact of the Opioid Epidemic and Associated Prescribing Restrictions on People Who Live With Chronic Noncancer Pain in Canada.

Jean-Luc Kaboré, M Gabrielle Pagé, Marc O Martel, Lise Dassieu, Maria Hudspith, Gregg Moor, Kathryn Sutton, Jean-Sébastien Roy, Owen D Williamson, Manon Choinière,

<h4>Objectives</h4>Little is known about the consequences of the opioid epidemic on people living with chronic noncancer pain (CNCP). This study examined this issue in people who lived in the most impacted province by opioid overdoses in Canada (British Columbia [BC]) or one of the least impacted (Quebec [QC]), and examined ... Read more >>

Clin J Pain (The Clinical journal of pain)
[2021, 37(8):607-615]

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Sickle Cell Disease and Pain: Is it all Vaso-occlusive Crises?

Zachary Ramsay, Rachel Bartlett, Amza Ali, Justin Grant, Georgiana Gordon-Strachan, Monika Asnani,

<h4>Objectives</h4>Acute pain is the main complication of sickle cell disease. Chronic pain (CP) and neuropathic pain (NP) may also be experienced, but have not been formally described in Jamaican patients. A cross-sectional study was conducted to determine their prevalence and characteristics, and to determine the common pain locations and modalities ... Read more >>

Clin J Pain (The Clinical journal of pain)
[2021, 37(8):583-590]

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An Exploration of Blood Marker-x-environment Interaction Effects on Pain Severity and Interference Scores in People with Acute Musculoskeletal Trauma.

Joshua Y Lee, Mohamad Fakhereddin, Joy C MacDermid, James M Elliott, Siobhan M Schabrun, David M Walton,

<h4>Objectives</h4>Explore the moderating effects of psychological or social variables on associations between biomarkers of inflammation/stress and clinical reports of pain.<h4>Methods</h4>This is a cross-sectional exploratory study. Data were drawn from the SYMBIOME longitudinal study (clinicaltrials.gov ID no. NCT02711085). Eligible participants were adults who presented to an Urgent Care Centre in Ontario, ... Read more >>

Clin J Pain (The Clinical journal of pain)
[2021, :]

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Clinimetric Properties of Self-reported Disability Scales for Whiplash: A Systematic Review for the Whiplash Core Outcome Set (CATWAD).

Alexandra R Griffin, Andrew M Leaver, Mohit Arora, David M Walton, Aimie Peek, Aila N Bandong, Michele Sterling, Trudy Rebbeck, ,

<h4>Objectives</h4>A core outcomes set (COS) for whiplash associated disorders (WAD) has been proposed to improve consistency of outcome reporting in clinical trials. Patient-reported disability was one outcome of interest within this COS. The aim of this review was to identify the most suitable tool for measuring self-reported disability in WAD, ... Read more >>

Clin J Pain (The Clinical journal of pain)
[2021, :]

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Clinical Effectiveness of an Outpatient Multidisciplinary Chronic Pain Management Telementoring Service.

William D Gersch, Thomas Delate, Karly M Bergquist, Karen Smith,

<h4>Objective</h4>To assess the effectiveness of a pain e-consult program (PEP), a multidisciplinary telementoring service based on the ECHO model to reduce opioid use, in the outpatient setting.<h4>Methods</h4>This was a retrospective, matched, cohort study conducted in an integrated healthcare delivery system. Adult patients without cancer and with a 90-day morphine milligram ... Read more >>

Clin J Pain (The Clinical journal of pain)
[2021, :]

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Safety of Epidural Steroid Injections for Lumbosacral Radicular Pain: Unmet Medical Need.

Steven P Cohen, Emileigh Greuber, Kip Vought, Dmitri Lissin,

<h4>Objective</h4>Epidural steroid injections (ESIs) are a commonly utilized treatment for lumbosacral radicular pain caused by intervertebral disc herniation or stenosis. Although effective in certain patient populations, ESIs have been associated with serious complications, including paralysis and death. In 2014, the US Food and Drug Administration (FDA) issued a safety warning ... Read more >>

Clin J Pain (The Clinical journal of pain)
[2021, :]

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Severe Pain Profiles and Associated Sociodemographic and Clinical Characteristics in Individuals with Sickle Cell Disease.

Mitchell R Knisely, Paula J Tanabe, Qing Yang, Rita Masese, Meilin Jiang, Nirmish R Shah,

<h4>Objectives</h4>To identify classes of individuals with sickle cell disease (SCD) who share distinct severe pain profiles and evaluate differences in demographic, clinical, and psychosocial characteristics between classes.<h4>Methods</h4>This exploratory, cross-sectional study used data collected for the SCD Implementation Consortium Research Registry at Duke University. Using Adult Sickle Cell Quality of Life-Measurement ... Read more >>

Clin J Pain (The Clinical journal of pain)
[2021, :]

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Evaluating the Safety of Continuous Infusion Lidocaine for Post-operative Pain.

Brian R Schuler, Kenneth E Lupi, Paul M Szumita, Mary P Kovacevic,

<h4>Objectives</h4>To evaluate the safety of intravenous lidocaine for post-operative pain and the impact on opioid requirements and pain scores.<h4>Methods</h4>This was a single-center, retrospective, single-arm analysis of adult patients who received intravenous lidocaine for post-operative pain from January 2016 to December 2019. Patients were excluded if they received lidocaine for any ... Read more >>

Clin J Pain (The Clinical journal of pain)
[2021, :]

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Pain Catastrophizing Throughout the Perioperative Period in Adolescents with Idiopathic Scoliosis.

Bianca Chabot, Hilary Sweatman, Don Daniel Ocay, Shajenth Premachandran, Mathieu Roy, Catherine E Ferland,

<h4>Objective</h4>Pain catastrophizing in children and adolescents has been associated to unfavourable post-surgical outcomes. However, pain catastrophizing is rarely measured throughout the perioperative period. Using a prospective longitudinal approach, the present study aimed to identify how pain catastrophizing changes over the perioperative period in pediatric surgical patients with adolescent idiopathic scoliosis.<h4>Methods</h4>Patients ... Read more >>

Clin J Pain (The Clinical journal of pain)
[2021, :]

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Non-pharmacologic Pain Management among Hospitalized Inpatients: A Randomized Waitlist Controlled Trial of Standard Virtual Reality (CGI VR) versus Video Capture VR (360° 3D/Stereoscopic Video Capture VR).

Mark B Powers, Emily Carl, Andrew Levihn-Coon, Melissa Van Veldhuizen, Andrew Caven, Jamie Pogue, Michelle Fresnedo, Emma D Turner, Maris Adams, Kiara Leonard, Haley Conroy, Crystal Lantrip, Thomas Caven, Claire Isbell, Justin Regner, Emily Garmon, Michael Foreman, Wayne Miller, Lorie A Fares, Per Carlbring, Michael W Otto, Daniel N Weiss, James Hughes, Jay M Bernhardt, Rob Roy, Jeeyun Oh, Ryan Copt, Jonathan MacClements, Ann Marie Warren, Benjamin Rosenfield, David Rosenfield, Sean Minns, Michael J Telch, Jasper A J Smits,

<h4>Objectives</h4>Non-pharmacologic pain management strategies are needed due to the growing opioid epidemic. While studies have examined the efficacy of virtual reality (VR) for pain reduction, there is little research in adult inpatient settings, and no studies comparing the relative efficacy of standard animated CGI VR (computer-generated imaging VR) to Video ... Read more >>

Clin J Pain (The Clinical journal of pain)
[2021, :]

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A Randomized Controlled Trial Evaluating the Analgesic Effect of the Combination of Methadone with Morphine for Cancer Related Pain.

Feliciano Contardo Nepomuceno Duarte, Leonardo Henrique da Cunha Ferraro, Alessandra Ferreira, Rioko Kimiko Sakata,

<h4>Context and objectives</h4>Although opioids play an indispensable role in the management of cancer-related pain, inadequate pain relief still occurs. The primary objective of this study was to evaluate whether the combination of a low dose of methadone with morphine promotes a reduction in opioid consumption; the secondary objectives were if ... Read more >>

Clin J Pain (The Clinical journal of pain)
[2021, :]

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Static and Dynamic Pain Sensitivity in Adults With Persistent Low Back Pain: Comparison to Healthy Controls and Associations With Movement-evoked Pain Versus Traditional Clinical Pain Measures.

Corey B Simon, Trevor A Lentz, Lindsay Ellis, Mark D Bishop, Roger B Fillingim, Joseph L Riley, Steven Z George,

<h4>Objectives</h4>Despite its impact, individual factors associated with persistent low back pain (LBP) remain poorly understood. This study investigated static and dynamic pain sensitivity in adults with persistent LBP versus pain-free controls; and investigated associations between pain sensitivity and 3 clinical pain measures: recalled, resting, and movement-evoked pain (MEP).<h4>Materials and methods</h4>A ... Read more >>

Clin J Pain (The Clinical journal of pain)
[2021, 37(7):494-503]

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Quantitative Sensory Testing in Women After Surgery for Breast Cancer: A Systematic Review and Narrative Synthesis.

Lore Dams, Elien Van der Gucht, Mira Meeus, Nele Devoogdt, Ann Smeets, Frauke Penen, Tom De Baerdemaecker, Vincent Haenen, Koen Bernar, Tessa De Vrieze, An De Groef,

<h4>Objectives</h4>Quantitative sensory testing (QST) is a noninvasive technique to evaluate functioning of the somatosensory system. In many women surgically treated for breast cancer (BC), somatosensory functioning is disturbed with high prevalence of sensory loss and/or pain. The aims of this systematic review were (1) to summarize literature about QST methods; ... Read more >>

Clin J Pain (The Clinical journal of pain)
[2021, 37(7):538-564]

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What Influences Outcomes From Inpatient Multidisciplinary Pain Management Programs?: A Systematic Review and Meta-analysis.

Gwyn N Lewis, Debbie J Bean,

<h4>Objectives</h4>Although inpatient multidisciplinary pain management programs (PMPs) are effective for chronic pain, not all patients benefit equally and there is limited evidence regarding predictors of outcome. This meta-analysis aimed to identify patient or program characteristics associated with outcomes from inpatient PMPs, and to examine the time course of effects following ... Read more >>

Clin J Pain (The Clinical journal of pain)
[2021, 37(7):504-523]

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