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Journal Clin Gastroenterol Hepatol

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Clinical Updates in Colorectal Endoscopic Submucosal Dissection.

Dennis Yang, Peter V Draganov,

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2021, :]

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Coffee consumption and lower liver stiffness: the risk for residual confounders should be considered.

Jiarong Xie, Lei Xu,

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2021, :]

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Esophageal dysmotility is associated with disease severity in eosinophilic esophagitis.

D A Carlson, C Shehata, N Gonsalves, I Hirano, S Peterson, J Prescott, D A Farina, J M Schauer, W Kou, P J Kahrilas, J E Pandolfino,

An association of eosinophilic esophagitis (EoE) with esophageal dysmotility has been described, however the related mechanism remains unclear. We aimed to evaluate clinical and physiologic characteristics, including esophageal distensibility, associated with secondary peristalsis in patients with EoE. 199 consecutive adult patients with EoE (ages 18-78, 32% female) that completed 16-cm ... Read more >>

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2021, :]

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Utility of ultrasound-guided attenuation parameter for grading steatosis with reference to MRI-PDFF in a large cohort.

Kento Imajo, Hidenori Toyoda, Satoshi Yasuda, Yasuaki Suzuki, Katsutoshi Sugimoto, Hidekatsu Kuroda, Tomoyuki Akita, Junko Tanaka, Yutaka Yasui, Nobuharu Tamaki, Masayuki Kurosaki, Namiki Izumi, Atsushi Nakajima, Takashi Kumada,

Ultrasound-guided attenuation parameter (UGAP) is recently developed for noninvasive evaluation of steatosis. However, reports on its usefulness in clinical practice are limited. This prospective multicenter study analyzed the diagnostic accuracy of grading steatosis with reference to magnetic resonance imaging-based proton density fat fraction (MRI-PDFF), a non-invasive method with high accuracy, ... Read more >>

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2021, :]

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Clinical and Patient Reported Outcomes from Patients with Non-alcoholic Fatty Liver Disease Across the World: Data from the Global NASH/NAFLD Registry.

Zobair M Younossi, Yusuf Yilmaz, Ming-Lung Yu, Vincent Wai-Sun Wong, Marlen Castellanos Fernandez, Vasily A Isakov, Ajay K Duseja, Nahum Mendez-Sanchez, Yuichiro Eguchi, Elisabetta Bugianesi, Patrizia Burra, Jacob George, Jian-Gao Fan, George V Papatheodoridis, Wah Kheong Chan, Khalid Alswat, Hamid S Saeed, Ashwani K Singal, Manuel Romero-Gomez, Stuart C Gordon, Stuart K Roberts, Mohamed El Kassas, Marcelo Kugelmas, Janus P Ong, Saleh Alqahtani, Mariam Ziayee, Brian Lam, Issah Younossi, Andrei Racila, Linda Henry, Maria Stepanova, ,

Globally, nonalcoholic fatty liver disease (NAFLD) is a common cause of chronic liver disease. We assessed clinical presentation and patient-reported outcomes (PROs) among NAFLD patients from different countries. Clinical, laboratory and PRO data (CLDQ-NASH, FACIT-F, WPAI) were collected from NAFLD patients seen in real-world practices and enrolled in the Global ... Read more >>

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2021, :]

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Sugar-Sweetened Beverage, Diet Soda, and Non-Alcoholic Fatty Liver Disease Over 6 Years: The Framingham Heart Study.

William Y Park, Ioanna Yiannakou, Julie M Petersen, Udo Hoffmann, Jiantao Ma, Michelle T Long,

<h4>Background</h4>Non-alcoholic fatty liver disease (NAFLD) is associated with sugar-sweetened beverage (SSB) consumption in cross-sectional studies. In a prospective cohort, we examined the association of beverage consumption (SSB and diet soda) with incident NAFLD and changes in hepatic fat in the Framingham Heart Study (FHS).<h4>Methods</h4>We conducted a prospective observational study of ... Read more >>

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2021, :]

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Decompensation in patients with advanced NAFLD - more questions that need answering.

Suprabhat Giri, Sridhar Sundaram,

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2021, :]

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Therapeutics, Placebo and the Importance of Hard Outcomes in Irritable Bowel Syndrome Research.

Jeremy R Glissen Brown, Anthony J Lembo,

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2021, :]

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Monitoring Colonoscopy Quality.

Ravi Thiruvengadam,

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2021, :]

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Cost-effectiveness of a Risk-Tailored Pancreatic Cancer Early Detection Strategy among Patients with New-Onset Diabetes.

Louise Wang, Frank I Scott, Ben Boursi, Kim A Reiss, Sankey Williams, Henry Glick, Yu-Xiao Yang,

<h4>Background & aims</h4>Screening for pancreatic ductal adenocarcinoma (PDAC) in asymptomatic adults is not recommended, but patients with new-onset diabetes (NoD) have an eight times higher risk of PDAC than expected. A novel risk-tailored early detection strategy targeting high-risk NoD patients might improve PDAC prognosis. We sought to evaluate the cost-effectiveness ... Read more >>

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2021, :]

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Underestimation of cirrhosis related mortality in the Medicare eligible population, 1999-2018.

Connor Griffin, Uchenna Agbim, Azaan Ramani, Nagasri Shankar, Fasiha Kanwal, Sumeet K Asrani,

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2021, :]

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Limitations of Heartburn and other Societies' Criteria in Barrett's Screening for Detecting De-novo Esophageal Adenocarcinoma.

Tarek Sawas, Shawn A Zamani, Sarah Killcoyne, Andrew Dullea, Kenneth K Wang, Prasad G Iyer, Rebecca C Fitzgerald, David A Katzka,

<h4>Background and aim</h4>Despite extensive Barrett's esophagus (BE) screening efforts, most patients with esophageal adenocarcinoma (EAC) present de novo. It is unclear how much of this problem is due to insensitivity or poor applications of current screening guidelines. We aimed to evaluate the sensitivity of guidelines by determining the proportion of ... Read more >>

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2021, :]

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Disease progression modelling for economic evaluation in non-alcoholic fatty liver disease - a systematic review.

Lina Gruneau, Mattias Ekstedt, Stergios Kechagias, Martin Henriksson,

<h4>Background & aims</h4>Globally, 25% of people have Non-Alcoholic Fatty Liver Disease (NAFLD) and currently there are no approved pharmacological treatments for NAFLD. With a slow disease progression, long-term impact of pharmacological treatments can only be assessed by complementing emerging clinical trial evidence by data from other sources in disease progression ... Read more >>

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2021, :]

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AGA Clinical Practice Update on Management of Medically Refractory Gastroparesis: Expert Review.

Brian E Lacy, Jan Tack, C Prakash Gyawali,

<h4>Description</h4>Delayed gastric emptying on objective testing defines gastroparesis, but symptoms overlap with functional dyspepsia, and do not correlate well with gastric emptying delay. This review outlines a strategy for defining, diagnosing and managing refractory gastroparesis.<h4>Methods</h4>The Best Practice Advice statements presented here were developed from review of existing literature combined with ... Read more >>

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2021, :]

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Pump Up the Volume? The Complex Relationship of Specialty and Colonoscopy Competency.

Rajesh N Keswani,

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2021, :]

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Longitudinal Changes in MR Elastography-based Biomarkers in Obese Patients Treated with Bariatric Surgery.

Jiahui Li, Alina M Allen, Vijay H Shah, Armando Manduca, Richard L Ehman, Meng Yin, ,

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2021, :]

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Pilot Randomized Controlled Trial of an Advance Care Planning Video Decision Tool for Patients with Advanced Liver Disease.

Nneka N Ufere, Blair Robinson, John Donlan, Teresa Indriolo, Judith Bloom, Abigail Scherrer, Nancy M Mason, Arpan Patel, Jennifer C Lai, Raymond T Chung, Angelo Volandes, Areej El-Jawahri,

<h4>Background & aims</h4>Transplant-ineligible patients with advanced liver disease rarely receive timely advance care planning (ACP). Tools are needed to educate these patients about medical interventions available at the end of life to promote ACP.<h4>Methods</h4>This single-site pilot randomized controlled trial assessed the feasibility, acceptability, and preliminary efficacy of an ACP video ... Read more >>

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2021, :]

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A gap in care leads to progression of fibrosis in eosinophilic esophagitis patients.

Nicole C Chang, Kisan P Thakkar, Corey J Ketchem, Swathi Eluri, Craig C Reed, Evan S Dellon,

<h4>Background and aims</h4>There are few data assessing disease progression in eosinophilic esophagitis (EoE) after diagnosis. We aimed to determine outcomes and assess for progression of fibrosis in EoE patients with a gap in their regular care.<h4>Methods</h4>In this retrospective cohort study of newly diagnosed EoE patients, a "gap" in care was ... Read more >>

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2021, :]

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Long-term outcome of gastric mild-moderate dysplasia: A real-world clinical experience.

Shiyu Xiao, Haoping Lu, Yan Xue, Rongli Cui, Lingmei Meng, Zhu Jin, Zhihao Yin, Liya Zhou,

<h4>Background & aims</h4>The natural course of gastric mild-moderate dysplasia in a country with high incidence of gastric cancer (GC) is relatively unknown. We aimed to determine the long-term cumulative incidence of and risk factors for advanced neoplasia in patients with gastric dysplasia.<h4>Methods</h4>This was a single center observational study including all ... Read more >>

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2021, :]

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Skills or Pills - Randomized trial comparing Hypnotherapy to Medical Treatment in children with Functional Nausea.

Pamela D Browne, Clara M A de Bruijn, Esther M Speksnijder, Bibiche den Hollander, Herbert M van Wering, Margreet M S Wessels, Michael Groeneweg, Joery Goede, Carla Frankenhuis, Ellen Tromp, Marc A Benninga, Arine M Vlieger,

<h4>Background & aims</h4>The potential effectiveness of gut-directed hypnotherapy (HT) is unknown for pediatric chronic nausea. This randomized controlled trial compared HT with standard medical treatment (SMT).<h4>Methods</h4>Hundred children (8-18 years) with chronic nausea and fulfilling functional nausea (FN) or functional dyspepsia (FD) criteria were randomly allocated (1:1) to HT or SMT, ... Read more >>

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2021, :]

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Impact of the COVID-19 Pandemic on Hospitalizations for Alcoholic Hepatitis or Cirrhosis in Alberta, Canada.

Abdel Aziz Shaheen, Kristine Kong, Christopher Ma, Chelsea Doktorchik, Carla S Coffin, Mark G Swain, Kelly W Burak, Stephen E Congly, Samuel S Lee, Matthew Sadler, Meredith Borman, Juan G Abraldes,

<h4>Background and aims</h4>COVID-19 pandemic lockdown and restrictions had significant disruption to patient care. We aimed to evaluate the impact of COVID-19 restrictions on hospitalizations of patients with alcoholic and non-alcoholic cirrhosis as well as alcoholic hepatitis (AH) in Alberta, Canada.<h4>Methods</h4>We used validated international clinical classification (ICD-9 and ICD-10) coding algorithms ... Read more >>

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2021, :]

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Authors' response to Letter to the Editor from Liu and Li regarding Risk for post-colonoscopy irritable bowel syndrome in patients with and without antibiotic exposure.

Ravy K Vajravelu, Jordan M Shapiro, Hashem B El-Serag,

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2021, :]

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Lymphangioma in a child managed with debulking surgery.

Takeshi Onda, Kamichika Hayashi, Masayuki Takano,

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2021, :]

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Factors associated with chronic de novo post-COVID gastrointestinal disorders in a metropolitan United States county.

Christopher Vélez, Mary Paz, Casey Silvernale, Lawrence W Stratton, Braden Kuo, Kyle Staller, ,

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2021, :]

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Metabolic syndrome and risk of gastrointestinal cancers: an investigation using large-scale molecular data.

Joseph A Rothwell, Mazda Jenab, Mojgan Karimi, Thérèse Truong, Yahya Mahamat-Saleh, Pietro Ferrari, S Ghazaleh Dashti, Tilman Kühn, Amanda J Cross, Gianluca Severi, Marc J Gunter, Neil Murphy,

<h4>Background and aims</h4>Gastrointestinal cancer risk is influenced by the presence of metabolic syndrome [MetS]. However, previous epidemiological studies lacked full serological biomarker data for the classification of MetS and the interaction of MetS with germline cancer risk variants is unknown.<h4>Methods</h4>We investigated the associations between MetS and gastrointestinal cancer risk (overall, ... Read more >>

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2021, :]

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