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Journal Clin Gastroenterol Hepatol

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Blue Notes.

Charles J Kahi,

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2022, 20(7):1425-1426]

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Dosing of Rifaximin Soluble Solid Dispersion Tablets in Adults With Cirrhosis: 2 Randomized, Placebo-Controlled Trials.

Jasmohan S Bajaj, Tarek I Hassanein, Nikolaos T Pyrsopoulos, Arun J Sanyal, Robert S Rahimi, Zeev Heimanson, Robert J Israel, Don C Rockey,

<h4>Background & aims</h4>Cirrhosis-related complications are a major burden. Rifaximin soluble solid dispersion (SSD) tablets (immediate-release [IR]; sustained extended-release [SER]) were designed to increase rifaximin water solubility. These analyses evaluate dosing for prevention of cirrhosis complication-related hospitalizations/mortality and overt hepatic encephalopathy (OHE) treatment.<h4>Methods</h4>Two phase 2, randomized, double-blind, placebo-controlled trials were conducted. ... Read more >>

Clin Gastroenterol Hepatol (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association)
[2022, :S1542-3565(22)00595-X]

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