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Mild Acquired Factor XIII Deficiency and Clinical Relevance at the ICU-A Retrospective Analysis.

Felix Carl Fabian Schmitt, Maik von der Forst, Wolfgang Miesbach, Sebastian Casu, Markus Alexander Weigand, Sonja Alesci,

Acquired FXIII deficiency is a relevant complication in the perioperative setting; however, we still have little evidence about the incidence and management of this rarely isolated coagulopathy. This study aims to help find the right value for the substitution of patients with an acquired mild FXIII deficiency. In this retrospective ... Read more >>

Clin Appl Thromb Hemost (Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis)
[2021, 27:10760296211024741]

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Reduced Activity of Protein S in Plasma: A Risk Factor for Venous Thromboembolism in the Japanese Population.

Xiuri Jin, Sachiko Kinoshita, Hiroyuki Kuma, Tomohide Tsuda, Tatsusada Yoshida, Dongchon Kang, Naotaka Hamasaki,

The quantitative assay of protein S can help in rapidly identifying carriers of abnormal protein S molecules through a simple procedure (by determining the total protein S mass, total protein S activity, and protein S-specific activity in blood), without genetic testing. To clarify the relationship between venous thromboembolism (VTE) and ... Read more >>

Clin Appl Thromb Hemost (Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis)
[2021, 27:10760296211033908]

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Neutrophil Gelatinase-Associated Lipocalin as an Early Predictor of Contrast-Induced Nephropathy Following Endovascular Aortic Repair for Abdominal Aortic Aneurysm.

Lubin Li, Juan Shao, Wenqiang Niu, Haijie Che, Fubo Song, Guolong Liu, Shaoying Lu,

To investigate serum neutrophil gelatinase-associated lipocalin (sNGAL) and urine neutrophil gelatinase-associated lipocalin (uNGAL) as early predictors of contrast-associated acute kidney injury(contrast-induced nephropathy)following endovascular aortic repair for abdominal aortic aneurysm. Prospective cohort study. Subjects included 202 consecutive patients with abdominal aortic aneurysm diagnosed between February 2016 and October 2018. We divided ... Read more >>

Clin Appl Thromb Hemost (Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis)
[2021, 27:10760296211025618]

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Evaluation of Deep Vein Thrombosis Risk Factors After Arthroscopic Posterior Cruciate Ligament Reconstruction: A Retrospective Observational Study.

Pu Ying, Wenge Ding, Xiaowei Jiang, Yue Xu, Yi Xue, Qiang Wang, Lei Zhu, Xiaoyu Dai,

We evaluated the risk factors of deep venous thrombosis (DVT) after knee arthroscopic posterior cruciate ligament (PCL) reconstruction in patients with only PCL injury. From August 2014 to December 2020, a total of 172 patients who had accepted knee arthroscopic PCL reconstruction underwent the color Doppler ultrasound of bilateral lower-extremities ... Read more >>

Clin Appl Thromb Hemost (Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis)
[2021, 27:10760296211030556]

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Acetylsalicylic Acid and COVID-19 Prevention: A Comment.

Pathum Sookaromdee, Viroj Wiwanitkit,

Clin Appl Thromb Hemost (Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis)
[2021, 27:10760296211027660]

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Rotational Thromboelastometry Reveals Distinct Coagulation Profiles for Patients With COVID-19 Depending on Disease Severity.

Mehmet Gökhan Gönenli, Zeynep Komesli, Said İncir, Özlem Yalçın, Olga Meltem Akay,

Identifying a hypercoagulable state in patients with COVID-19 may help identify those at risk for virus-induced thromboembolic events and improve clinical outcomes using personalized therapeutic approaches. Herein, we aimed to perform a global assessment of the patients' hemostatic system with COVID-19 using rotational thromboelastometry (ROTEM) and to describe whether patients ... Read more >>

Clin Appl Thromb Hemost (Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis)
[2021, 27:10760296211027653]

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Prediction and Diagnosis of Venous Thromboembolism Using Artificial Intelligence Approaches: A Systematic Review and Meta-Analysis.

Qi Wang, Lili Yuan, Xianhui Ding, Zhiming Zhou,

Venous thromboembolism (VTE) is a fatal disease and has become a burden on the global health system. Recent studies have suggested that artificial intelligence (AI) could be used to make a diagnosis and predict venous thrombosis more accurately. Thus, we performed a meta-analysis to better evaluate the performance of AI ... Read more >>

Clin Appl Thromb Hemost (Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis)
[2021, 27:10760296211021162]

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Expected Viscosity After COVID-19 Vaccination, Hyperviscosity and Previous COVID-19.

Beuy Joob, Viroj Wiwanitkit,

Clin Appl Thromb Hemost (Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis)
[2021, 27:10760296211020833]

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Increased Levels of Platelets and Endothelial-Derived Microparticles in Patients With Non-Valvular Atrial Fibrillation During Rivaroxaban Therapy.

Aleksandra Lenart-Migdalska, Leszek Drabik, Magdalena Kaźnica-Wiatr, Lidia Tomkiewicz-Pająk, Piotr Podolec, Maria Olszowska,

It is known that atrial fibrillation (AF) is associated with the procoagulant state. Several studies have reported an increase of circulating microparticles in AF, which may be linked to a hypercoagulable state, atrial thrombosis and thromboembolism. We evaluated in our study alterations in both platelet (PMP, CD42b) and endothelial-derived (EMP, ... Read more >>

Clin Appl Thromb Hemost (Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis)
[2021, 27:10760296211019465]

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Biomarkers of Thrombo-Inflammatory Responses in Pulmonary Embolism Patients With Pre-Existing Versus New-Onset Atrial Fibrillation.

Dimpi Patel, Amir Darki, Debra Hoppensteadt, Iman Darwish, Mushabbar Syed, Yevgeniy Brailovsky, Jawed Fareed,

Pulmonary embolism (PE) patients have an increased prevalence and incidence of atrial fibrillation (AF). Because comorbid AF increases risk of morbidity and mortality, we sought to investigate the role of thrombo-inflammatory biomarkers in risk stratifying patients who experience an acute PE episode. Study participants were enrolled from a Pulmonary Embolism ... Read more >>

Clin Appl Thromb Hemost (Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis)
[2021, 27:10760296211014964]

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Fondaparinux Pre-, Peri-, and/or Postpartum for the Prophylaxis/Treatment of Venous Thromboembolism (FondaPPP).

Carl-Erik Dempfle, Jürgen Koscielny, Edelgard Lindhoff-Last, Birgit Linnemann, Irene Bux-Gewehr, Günther Kappert, Ute Scholz, Stefan Kropff, Sonja Eberle, Peter Bramlage, Andreas Heinken,

We analyzed data for women who received fondaparinux for ≥7 days during pregnancy. The study retrospectively included women who received fondaparinux pre-, peri- and/or postpartum for ≥7 days for prophylaxis/venous thromboembolism (VTE) treatment at German specialist centers (2004-2010). Data on pregnancy, VTE risk factors, anticoagulant treatment, pregnancy outcome and adverse ... Read more >>

Clin Appl Thromb Hemost (Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis)
[2021, 27:10760296211014575]

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Splanchnic Vein Thrombosis in Acute Pancreatitis and Its Consequences.

Łukasz Nawacki, Jarosław Matykiewicz, Ewa Stochmal, Stanisław Głuszek,

Splanchnic vein thrombosis (SVT) is a serious vascular complication that can occur in patients with acute pancreatitis. We assessed the incidence of SVT and its relationship with acute pancreatitis (AP) and associated complications. We carried out a retrospective analysis of medical histories from patients hospitalized with AP in a single ... Read more >>

Clin Appl Thromb Hemost (Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis)
[2021, 27:10760296211010260]

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Anticoagulation and In-Hospital Mortality From Coronavirus Disease 2019: A Systematic Review and Meta-Analysis.

Chatphatai Moonla, Darintr Sosothikul, Thita Chiasakul, Ponlapat Rojnuckarin, Noppacharn Uaprasert,

Hypercoagulability in coronavirus disease 2019 (COVID-19) may aggravate disease severity during hospitalization but the reported survival benefits from anticoagulation (AC) vary among studies. We performed a literature research to estimate pooled odds ratios (ORs) of in-hospital mortality and major bleeding comparing among intermediate-to-therapeutic dose AC, prophylactic dose AC, and no ... Read more >>

Clin Appl Thromb Hemost (Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis)
[2021, 27:10760296211008999]

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Do Inpatients Receive Risk-Based Prophylactic Treatment for Thrombotic Events?

Armin Nemani, Constantin von Zur Mühlen, Friederike Steffen, Johannes Schulte, Christoph Bode, Marvin Krohn-Grimberghe,

<h4>Background</h4>Current guidelines recommend risk-based use of prophylaxis for preventing medical inpatients from venous thromboembolism (VTE). Little is known about the current prescription practice, and even less whether differences between subspecialists like cardiologists, usually treating patients with thrombotic or thromboembolic diseases, and gastroenterologists, treating more patients with gastrointestinal bleeding complications, exist.<h4>Methods</h4>We ... Read more >>

Clin Appl Thromb Hemost (Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis)
[2021, 27:1076029621995563]

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Portuguese Consensus and Recommendations for Acquired Coagulopathic Bleeding Management (CCBM).

Manuela Gomes, Anabela Rodrigues, Alexandre Carrilho, José Aguiar, Luciana Gonçalves, Fernando Fernandez-Llimos, Filipa Duarte-Ramos, Joana Rodrigues,

We aimed to determine how Portuguese physicians handle major bleeding. We also aim to establish global diagnostic and therapeutic recommendations to be followed in clinical practice by using a step-wise approach of evidence generation. This study followed a three-step process: a steering committee desk review, a Delphi technique, an expert ... Read more >>

Clin Appl Thromb Hemost (Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis)
[2021, 27:10760296211003984]

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Considerations for Patients With Peripheral Artery Disease During the COVID-19 Pandemic.

Serdar Farhan, Haroon Kamran, Birgit Vogel, Karan Garg, Ajit Rao, Navneet Narula, Glenn Jacobowitz, Arthur Tarricone, Vishal Kapur, Peter Faries, Michael Marin, Jagat Narula, Robert Lookstein, Jeffrey W Olin, Prakash Krishnan,

New York City was one of the epicenters of the COVID-19 pandemic. The management of peripheral artery disease (PAD) during this time has been a major challenge for health care systems and medical personnel. This document is based on the experiences of experts from various medical fields involved in the ... Read more >>

Clin Appl Thromb Hemost (Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis)
[2021, 27:1076029620986877]

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Performance Characteristics of DOAC Dipstick in Determining Direct Oral Anticoagulants in Urine.

Job Harenberg, Andrea Martini, Shanshan Du, Sandra Krämer, Christel Weiss, Svetlana Hetjens,

Testing for direct oral anticoagulants (DOACs) in patient urine may facilitate medical treatment decisions. The aim of this study was to investigate interobserver variability by 2 independent observers compared to laboratory staff in the visual interpretation of factor Xa (DXI) and thrombin inhibitors (DTI) using the DOAC Dipstick test. We ... Read more >>

Clin Appl Thromb Hemost (Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis)
[2021, 27:1076029621993550]

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The Net Clinical Benefit of Rivaroxaban Compared to Low-Molecular-Weight Heparin in the Treatment of Cancer-Associated Thrombosis: Systematic Review and Meta-Analysis.

Mouhand F H Mohamed, Mohamad Nabil ElShafei, Mohamed Badie Ahmed, Lina O Abdalla, Israa Ahmed, Abdel-Naser Elzouki, Mohammed Ibn-Mas'ud Danjuma,

Cancer-associated thrombosis (CAT) carries significant morbidity and mortality. Low-molecular-weight heparin (LMWH) remains the standard of care, with recent systematic studies suggesting the efficacy and safety of rivaroxaban in the treatment of CAT. Uncertainty, however, remains regarding rivaroxaban efficacy and safety in real-world settings. We performed a systematic review and meta-analysis ... Read more >>

Clin Appl Thromb Hemost (Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis)
[2021, 27:1076029620940046]

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The Evaluation of APTT Reagents in Reference Plasma, Recombinant FVIII Products; Kovaltry® and Jivi® Using CWA, Including sTF/7FIX Assay.

Hideo Wada, Katsuya Shiraki, Takeshi Matsumoto, Kohshi Ohishi, Hideto Shimpo, Yumi Sakano, Hiroko Nishii, Motomu Shimaoka,

The FVIII activity in patients treated with several extended half-life FVIII (EHL-FVIII) agents different when various activated partial thromboplastin time (APTT) reagents were used. The present study examined the difference in clot waveform analysis (CWA) findings and FVIII activity when various APTT reagents and CWA were used. The CWA including ... Read more >>

Clin Appl Thromb Hemost (Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis)
[2021, 27:1076029620976913]

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Solid Tumor Complicated With Venous Thromboembolism: A 10-Year Retrospective Cross-Sectional Study.

Miao Peng, Shengli Yang, Guiling Li, Tao Zhang, Xiaojuan Qin, Chen Shi, Jian Chang, Mengni Chen, Chen Chen, Bingjie Li, Sihang Cao, Ting Li, Renwang Chen, Prapti Bakhshi, Min Jin, Gang Wu, Jianli Hu,

Venous thromboembolism (VTE), including pulmonary embolism (PE) and deep vein thrombosis (DVT) occurs more frequently in cancer patients than in the general population. A retrospective cross-sectional study was carried out in patients with solid tumor complicated with VTE admitted to the Cancer Center, Union Hospital, Tongji Medical College, Huazhong University ... Read more >>

Clin Appl Thromb Hemost (Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis)
[2021, 27:1076029620975484]

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Phase 4 Safety and Efficacy Study of Antihemophilic Factor (Recombinant) in Previously Treated Chinese Patients With Severe/Moderately Severe Hemophilia A.

Yongqiang Zhao, Yu Hu, Jie Jin, Xielan Zhao, Xuefeng Wang, Runhui Wu, Depei Wu, Renchi Yang, Feng'e Yang, Qun Hu, Juan Wang, Hai Fang, Werner Engl,

Antihemophilic factor (recombinant) (rAHF; ADVATE<sup>®</sup>; Baxalta US Inc., a Takeda company, Lexington, MA, USA) is indicated for the treatment and prevention of bleeding in patients with hemophilia A. We aimed to assess the safety and efficacy of standard prophylaxis versus on-demand treatment with rAHF in previously treated Chinese patients with ... Read more >>

Clin Appl Thromb Hemost (Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis)
[2021, 27:1076029621989811]

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Time Course of Inflammatory and Procoagulant Markers in the Early Period After Total Hip Replacement.

Peter Poredos, Pavel Poredos, Mateja K Jezovnik, Ana Mavric, Lara Leben, Mojca Bozic Mijovski, Paula Maia, Sandra Haddad, Jawed Fareed,

Our study aimed to investigate the levels and time-course of systemic inflammatory and hemostasis markers in the early postoperative period in patients undergoing total hip replacement (THR). The study included 70 patients of both sexes, average age 68.4 ± 10.9 years. Levels of inflammatory and hemostasis markers were measured before ... Read more >>

Clin Appl Thromb Hemost (Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis)
[2021, 27:1076029620985941]

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Systemic Coagulopathy in Hospitalized Patients With Coronavirus Disease 2019: A Systematic Review and Meta-Analysis.

Noppacharn Uaprasert, Chatphatai Moonla, Darintr Sosothikul, Ponlapat Rojnuckarin, Thita Chiasakul,

Coagulation activation has been reported in several cohorts of patients Coronavirus Disease 2019 (COVID-19). However, the true burden of systemic coagulopathy in COVID-19 remains unknown. In this systematic review and meta-analysis, we performed a literature search using PubMed, EMBASE, and Cochrane Database to identify studies that reported the prevalence of ... Read more >>

Clin Appl Thromb Hemost (Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis)
[2021, 27:1076029620987629]

Cited: 3 times

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The Perioperative Deep Vein Thrombosis in Lower Extremities in Patients With Pelvic Fracture: A Case-Control Study.

Yun Yan, Baobao Zhang, Jie Yang, Yan Zhang, Lei Zhang, Dan Wang, Jing Gao, Lianzhi He, Pengfei Wang, Yan Zhuang, Kun Zhang, Ping Liu,

This study was to investigate the incidences of DVT in lower extremities after pelvic fracture before and after operation, and explore the risk factors. The records of patients with pelvic fractures receiving operation were collected. The patients were examined by preoperative and postoperative ultrasonography, and divided into thrombosis group and ... Read more >>

Clin Appl Thromb Hemost (Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis)
[2021, 27:10760296211033024]

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The Association of Coagulation Indicators and Coagulant Agents With 30-Day Mortality of Critical Diabetics.

Yingxin Huang, Zhihua Zhong, Fanna Liu,

Diabetes, regarded as a global health concerned disease, was focused by the World Health Organization (WHO). Patients with diabetes may have a hypercoagulable and hypo-fibrinolysis state. There is lots of research about cardiovascular effects on diabetes patients, but less about the coagulation system. This study is designed to investigate the ... Read more >>

Clin Appl Thromb Hemost (Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis)
[2021, 27:10760296211026385]

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