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Poor Increase in Pulse Pressure During Cardiopulmonary Exercise Testing Predicts Cardiovascular Death of Patients With Heart Failure With Reduced Ejection Fraction.

Taisuke Nakade, Hitoshi Adachi, Makoto Murata, Shigeto Naito,

BACKGROUND:The increase in stroke volume during inotropic stimulation in patients with heart failure with reduced ejection fraction (HFrEF) is called the "pump function reserve." Few studies have reported on the relationship between pump function reserve and HF prognosis. In HFrEF patients who have pump function reserve, stroke volume increases during ... Read more >>

Circ. J. (Circulation journal : official journal of the Japanese Circulation Society)
[2020, :]

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Cancer Therapeutics-Related Cardiac Dysfunction - Insights From Bench and Bedside of Onco-Cardiology.

Hiroshi Kadowaki, Hiroshi Akazawa, Junichi Ishida, Issei Komuro,

Improvements in the long-term survival of cancer patients have led to growing awareness of the clinical importance of cancer therapeutics-related cardiac dysfunction (CTRCD), which can have a considerable effect on the prognosis and quality of life of cancer patients and survivors. Under such circumstances, onco-cardiology/cardio-oncology has emerged as a new ... Read more >>

Circ. J. (Circulation journal : official journal of the Japanese Circulation Society)
[2020, :]

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Detailed Characterization of Vulnerable Plaque Morphology by High-Resolution Intravascular Ultrasound.

Hirohiko Ando, Hirofumi Ohashi, Yusuke Nakano, Hiroaki Takashima, Tetsuya Amano,

Circ. J. (Circulation journal : official journal of the Japanese Circulation Society)
[2020, :]

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Incidence of Cardiovascular Events and Safety Profile of Prasugrel in Korean Patients With Acute Coronary Syndrome.

Min-Ku Chon, Soon-Myung Jung, Soo-Yong Lee, Sang-Hyun Lee, Ki-Won Hwang, Jin-Hee Choi, Jeong-Su Kim, Yong-Hyun Park, June-Hong Kim, Kook-Jin Chun,

BACKGROUND:Dual antiplatelet therapy is commonly used for patients with acute coronary syndrome (ACS). This study aimed to evaluate the safety and efficacy of aspirin and prasugrel at standard dosages in Korean patients using clinical outcome data.Methods and Results:For this prospective multicenter phase IV post-marketing surveillance (PMS) study, ACS patients from 29 July ... Read more >>

Circ. J. (Circulation journal : official journal of the Japanese Circulation Society)
[2020, :]

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Missing P Wave on Electrocardiogram in Hypermagnesemia.

Hiroaki Nishioka,

Circ. J. (Circulation journal : official journal of the Japanese Circulation Society)
[2020, :]

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Pulsatile Strangulation of the Aorta - A Rare Presentation and Etiology of Infective Endocarditis.

Wei-Ting Chang, Zhih-Cherng Chen,

Circ. J. (Circulation journal : official journal of the Japanese Circulation Society)
[2020, :]

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Earlier Diagnosis of Peripartum Cardiomyopathy (PPCM).

James D Fett,

Circ. J. (Circulation journal : official journal of the Japanese Circulation Society)
[2020, :]

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Vasculopathy After Transradial Catheterization in a Scleroderma Patient.

Takenobu Shimada, Seiji Habara, Hiroyuki Tanaka, Kazushige Kadota,

Circ. J. (Circulation journal : official journal of the Japanese Circulation Society)
[2020, :]

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What Is the Optimal Dual Antiplatelet Therapy Strategy After Percutaneous Coronary Intervention in the Era of New-Generation Drug-Eluting Stent?

Hiroaki Yokoyama,

Circ. J. (Circulation journal : official journal of the Japanese Circulation Society)
[2020, :]

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Clinical Differences of Recent Myocardial Infarction Compared With Acute Myocardial Infarction - Insights From the Tokyo CCU Network Multicenter Registry.

Ryosuke Ito, Jun Yamashita, Taishiro Chikamori, Seita Kondo, Yuya Mitsuhashi, Hiroshi Iwata, Mike Saji, Taku Asano, Kohei Wakabayashi, Kazuyuki Yahagi, Toshiro Shinke, Takaaki Mase, Kaito Abe, Hideki Miyachi, Satoshi Higuchi, Mikio Kishi, Hiroyuki Tanaka, Masao Yamasaki, Katsumi Miyauchi, Takeshi Yamamoto, Ken Nagao, Morimasa Takayama,

BACKGROUND:Characteristics and treatment outcomes of acute myocardial infarction (AMI) patients have been studied; however, those of recent myocardial infarction (RMI) patients remain unclear. This study aimed to clarify characteristics, treatment strategy, and in-hospital outcomes of RMI patients in the Tokyo CCU network database.Methods and Results:In total, 1,853 RMI and 12,494 AMI patients ... Read more >>

Circ. J. (Circulation journal : official journal of the Japanese Circulation Society)
[2020, :]

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Efficacy of Pulmonary Artery Pulsatility Index as a Measure of Right Ventricular Dysfunction in Stable Phase of Dilated Cardiomyopathy.

Tasuku Kuwayama, Ryota Morimoto, Hideo Oishi, Hiroo Kato, Yuki Kimura, Shingo Kazama, Naoki Shibata, Yoshihito Arao, Shogo Yamaguchi, Hiroaki Hiraiwa, Toru Kondo, Kenji Furusawa, Takahiro Okumura, Toyoaki Murohara,

BACKGROUND:Right ventricular dysfunction (RVD) in the setting of left ventricular (LV) myocardial damage is a major cause of morbidity and mortality, and the pulmonary artery pulsatility index (PAPi) is a novel hemodynamic index shown to predict RVD in advanced heart failure. However, it is unknown whether PAPi can predict the ... Read more >>

Circ. J. (Circulation journal : official journal of the Japanese Circulation Society)
[2020, :]

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Gastrointestinal Bleeding From Oral Anticoagulant Therapy Among Japanese Patients With Atrial Fibrillation Identified From the SAKURA Atrial Fibrillation Registry.

Nobuhiro Murata, Yasuo Okumura, Koichi Nagashima, Daisuke Fukamachi, Katsuaki Yokoyama, Naoya Matsumoto, Eizo Tachibana, Keiichiro Kuronuma, Koji Oiwa, Michiaki Matsumoto, Toshiaki Kojima, Shoji Hanada, Kazumiki Nomoto, Ken Arima, Fumiyuki Takahashi, Tomobumi Kotani, Yukitoshi Ikeya, Seiji Fukushima, Satoru Itou, Kunio Kondo, Masaaki Chiku, Yasumi Ohno, Motoyuki Onikura, Atsushi Hirayama, ,

BACKGROUND:In the Japanese clinical setting, the prevalence, potential cofounders of gastrointestinal (GI) bleeding from anticoagulant therapy, including direct oral anticoagulants (DOACs) and warfarin, and prognosis after GI bleeding are unclear.Methods and Results:We examined about GI bleeding from anticoagulant therapy using data from the SAKURA AF Registry, a prospective multicenter registry in Japan. ... Read more >>

Circ. J. (Circulation journal : official journal of the Japanese Circulation Society)
[2020, :]

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Clinical Characteristics and Outcomes of Heart Failure Patients With Long-Term Care Insurance - Insights From the Kitakawachi Clinical Background and Outcome of Heart Failure Registry.

Kensuke Takabayashi, Kotaro Iwatsu, Tsutomu Ikeda, Yuko Morikami, Tahei Ichinohe, Takashi Yamamoto, Kotoe Takenaka, Hiroyuki Takenaka, Hiroyuki Muranaka, Ryoko Fujita, Miyuki Okuda, Osamu Nakajima, Hitoshi Koito, Yuka Terasaki, Tetsuhisa Kitamura, Shouji Kitaguchi, Ryuji Nohara,

BACKGROUND:In Japan, the long-term care insurance (LTCI) system has an important role in helping elderly people, but there have been no clinical studies that have examined the relationship between the LTCI and prognosis for patients with acute heart failure (HF).Methods and Results:This registry was a prospective multicenter cohort, 1,253 patients were enrolled ... Read more >>

Circ. J. (Circulation journal : official journal of the Japanese Circulation Society)
[2020, :]

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Comparison Between Clopidogrel and Prasugrel Associated With CYP2C19 Genotypes in Patients Receiving Percutaneous Coronary Intervention in a Japanese Population.

Yuichi Sawayama, Takashi Yamamoto, Yukinori Tomita, Kohei Asada, Noriaki Yagi, Megumi Fukuyama, Akashi Miyamoto, Hiroshi Sakai, Tomoya Ozawa, Tetsuichiro Isono, Daiki Hira, Tomohiro Terada, Minoru Horie, Yoshihisa Nakagawa,

BACKGROUND:The association between cytochrome P450 (CYP) 2C19 genotypes and adverse events in patients treated with clopidogrel or prasugrel after percutaneous coronary intervention (PCI) in the Japanese population is unclear.Methods and Results:This study consisted of 1,580 patients whoseCYP2C19genotypes were assessed at Shiga University of Medical Science Hospital, and 193 clopidogrel-treated and 217 prasugrel-treated ... Read more >>

Circ. J. (Circulation journal : official journal of the Japanese Circulation Society)
[2020, :]

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Overhanging Bioresorbable Vascular Scaffold Observed on Angioscopy 1 Year After Implantation.

Hiroyuki Inoue, Atsunori Okamura, Mutsumi Iwamoto, Akinori Sumiyoshi, Kota Tanaka, Kohtaro Takayasu, Katsutoshi Kawamura, Yasushi Koyama, Koichi Inoue, Katsuomi Iwakura, Kenshi Fujii, Yasushi Sakata, Hiroyuki Nagai,

Circ. J. (Circulation journal : official journal of the Japanese Circulation Society)
[2020, :]

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Clopidogrel Monotherapy vs. Aspirin Monotherapy Following Short-Term Dual Antiplatelet Therapy in Patients Receiving Everolimus-Eluting Coronary Stent Implantation.

Masahiro Natsuaki, Takeshi Morimoto, Hirotoshi Watanabe, Mitsuru Abe, Kazuya Kawai, Koichi Nakao, Kenji Ando, Kengo Tanabe, Yuji Ikari, Keiichi Igarashi Hanaoka, Yoshihiro Morino, Ken Kozuma, Kazushige Kadota, Takeshi Kimura, ,

BACKGROUND:There is a scarcity of data on short-duration dual antiplatelet therapy (DAPT) followed by P2Y12 inhibitor monotherapy as compared with aspirin monotherapy after percutaneous coronary intervention (PCI).Methods and Results:STOPDAPT-1 is a prospective trial enrolling patients who agreed to 3-month DAPT followed by aspirin monotherapy after everolimus-eluting stent (EES) implantation. STOPDAPT-2 is a ... Read more >>

Circ. J. (Circulation journal : official journal of the Japanese Circulation Society)
[2020, :]

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Doppler-Derived Intrarenal Venous Flow Mirrors Right-Sided Heart Hemodynamics in Patients With Cardiovascular Disease.

Yoshihiro Seo, Noriko Iida, Masayoshi Yamamoto, Tomoko Ishizu, Masaki Ieda, Nobuyuki Ohte,

BACKGROUND:Interruption in Doppler intrarenal venous flow (IRVF) has been used in assessing renal congestion and in the prediction of prognosis of cardiovascular diseases. However, there is a paucity of pathophysiological knowledge, so we aimed to clarify the determinants of IRVF interruption.Methods and Results:Intrarenal Doppler studies were performed within 24 h before right-side ... Read more >>

Circ. J. (Circulation journal : official journal of the Japanese Circulation Society)
[2020, :]

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Independent Factors for In-Hospital Death Following Drug-Eluting Stent Thrombosis From the Japanese Adverse Event Report System.

Yoshiaki Mitsutake, Akihide Konishi, Nobuhiro Handa, Mami Ho, Haruki Shirato, Takuya Ito, Kazuhisa Koike, Shuichi Mochizuki, Kensuke Ishii,

BACKGROUND:Stent thrombosis (ST) is a serious complication after drug-eluting stents (DES) implantation. To identify the risk factors of mortality following ST, we evaluated adverse event reports used for safety measures after approval.Methods and Results:Between July 2004 and August 2019, 2,887 ST case reports were submitted to the Pharmaceutical and Medical Device Agency. ... Read more >>

Circ. J. (Circulation journal : official journal of the Japanese Circulation Society)
[2020, :]

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Optimal Timing of Venoarterial-Extracorporeal Membrane Oxygenation in Acute Myocardial Infarction Patients Suffering From Refractory Cardiogenic Shock.

Ki Hong Choi, Jeong Hoon Yang, David Hong, Taek Kyu Park, Joo Myung Lee, Young Bin Song, Joo-Yong Hahn, Seung-Hyuk Choi, Jin-Ho Choi, Su Ryeun Chung, Yang Hyun Cho, Dong Seop Jeong, Kiick Sung, Wook Sung Kim, Young Tak Lee, Hyeon-Cheol Gwon,

BACKGROUND:Although there is an increase in the use of mechanical circulatory support devices to rescue patients with acute myocardial infarction (AMI) complicated by refractory cardiogenic shock (CS), the optimal timing of the application remains controversial. Therefore, this study aimed to compare the clinical outcomes between venoarterial-extracorporeal membrane oxygenation (VA-ECMO) insertion ... Read more >>

Circ. J. (Circulation journal : official journal of the Japanese Circulation Society)
[2020, :]

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Impact of the Temporal Relationship Between Atrial Fibrillation and Heart Failure on Prognosis After Ablation.

Aki Tsuji, Masaharu Masuda, Mitsutoshi Asai, Osamu Iida, Shin Okamoto, Takayuki Ishihara, Kiyonori Nanto, Takashi Kanda, Takuya Tsujimura, Yasuhiro Matsuda, Shota Okuno, Yosuke Hata, Toshiaki Mano,

BACKGROUND:The purpose of this study was to elucidate the effect of the temporal relationship between atrial fibrillation (AF) and heart failure (HF) on clinical outcomes after catheter ablation.Methods and Results:We included 129 consecutive patients with AF and HF who underwent catheter ablation in hospital from December 2014 to September 2017. The patients ... Read more >>

Circ. J. (Circulation journal : official journal of the Japanese Circulation Society)
[2020, :]

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Prevalence of the Academic Research Consortium for High Bleeding Risk Criteria and Prognostic Value of a Simplified Definition.

Katsuya Miura, Takenobu Shimada, Masanobu Ohya, Ryosuke Murai, Hidewo Amano, Shunsuke Kubo, Takeshi Tada, Hiroyuki Tanaka, Yasushi Fuku, Tsuyoshi Goto, Kazushige Kadota,

BACKGROUND:The Academic Research Consortium for High Bleeding Risk (ARC-HBR) criteria have been suggested as the standard definition of HBR. However, the prevalence of individual criteria and their prognostic value for long-term bleeding events after percutaneous coronary intervention are scarcely studied.Methods and Results:The study population comprised 1,193 patients treated with everolimus-eluting stents between ... Read more >>

Circ. J. (Circulation journal : official journal of the Japanese Circulation Society)
[2020, :]

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The Association of In-Hospital Transcatheter Aortic Valve Replacement Availability on Outcomes of Surgical Aortic Valve Replacement in Elderly Patients.

Minoru Tabata, Hiraku Kumamaru, Aya Ono, Hiroaki Miyata, Yasunori Sato, Noboru Motomura,

BACKGROUND:Transcatheter aortic valve replacement (TAVR) has been performed more and more frequently in elderly patients with aortic stenosis. We investigated the association of in-hospital availability of TAVR on outcomes of surgical aortic valve replacement (SAVR) in the era of TAVR.Methods and Results:We utilized data from the Japan Adult Cardiovascular Surgery Database. Between ... Read more >>

Circ. J. (Circulation journal : official journal of the Japanese Circulation Society)
[2020, :]

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Hypertrophic Cardiomyopathy - A Heterogeneous and Lifelong Disease in the Real World.

Hiroaki Kitaoka, Toru Kubo, Yoshinori L Doi,

Hypertrophic cardiomyopathy (HCM) is the most frequent hereditary cardiomyopathy, showing an autosomal-dominant f inheritance. A great deal of attention has been paid to genetics, left ventricular tract obstruction and the prediction and prevention of sudden cardiac death in HCM. Needless to say, these are very important, but we should recognize ... Read more >>

Circ. J. (Circulation journal : official journal of the Japanese Circulation Society)
[2020, 84(8):1218-1226]

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Risk of Pulmonary Arterial Hypertension During Qing-Dai Use for the Treatment of Ulcerative Colitis.

Shiro Adachi, Yoshihisa Nakano, Takahisa Kondo,

Circ. J. (Circulation journal : official journal of the Japanese Circulation Society)
[2020, 84(8):1235-1236]

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2-Year Outcomes of Left Atrial Appendage Occlusion With WATCHMAN in Japanese Atrial Fibrillation Patients.

Masahide Harada,

Circ. J. (Circulation journal : official journal of the Japanese Circulation Society)
[2020, 84(8):1227-1229]

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