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Journal Case Rep Nephrol Dial

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Hemodialysis Initiation in Oldest-Old Patients: A Case Series.

Ryoichi Maenosono, Tomohisa Matsunaga, Yuki Yoshikawa, Kazuki Nishimura, Haruhiko Onaka, Kazumasa Komura, Hirofumi Uehara, Haruhito Azuma,

With an increase in the number of older adults worldwide, the oldest-old population, defined as individuals over the age of 90, is also growing. Japan is now facing the problem of a "super-aged society" in which over 21% of the population is aged over 65. The oldest-old constituted 1.8% (2.31 ... Read more >>

Case Rep Nephrol Dial (Case reports in nephrology and dialysis)
[2021, 11(3):286-291]

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An Overlooked Link between IgA Nephropathy and Lithium Toxicity: A Case Report.

Sushil K Mehandru, Supreet Kaur, Aisha Ghias, Mohamed Bakr, Arif Asif, Tushar J Vachharajani,

Lithium is one of the first-line agents for treating bipolar disorder. Although this agent is highly effective in treating mood disorders, renal toxicity is a frequent side effect. Lithium metabolism is affected by sodium-lithium counter-transporter (SLC-T) in erythrocytes. The high activity of SLC-T can result in decreased urinary lithium clearance ... Read more >>

Case Rep Nephrol Dial (Case reports in nephrology and dialysis)
[2021, 11(3):301-307]

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Etanercept-Induced Anti-Glomerular Basement Membrane Disease.

Saif Al-Chalabi, Henry H L Wu, Rajkumar Chinnadurai, Arvind Ponnusamy,

Anti-glomerular basement membrane (anti-GBM) disease is a rare form of small-vessel vasculitis that typically causes rapidly progressive glomerulonephritis with or without alveolar haemorrhage. Previously, there has only been one reported case of tumour necrosis factor-α (TNF-α) antagonist-induced anti-GBM disease. Here, we describe the first reported case of etanercept-induced anti-GBM disease. ... Read more >>

Case Rep Nephrol Dial (Case reports in nephrology and dialysis)
[2021, 11(3):292-300]

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Median Nerve and Ulnar Nerve Entrapment with Cubital Tunnel Syndrome in a Hemodialysis Patient Following Creation of an Arteriovenous Fistula.

Ramanath Dukkipati, Aaron Richler, Anuja Shah, Christian de Virgilio,

Neurological and vascular complications associated with creation of arteriovenous access need to be recognized promptly to deliver appropriate interventions for relief of symptoms and avoid loss of function of the involved extremity. We present here a 55-year-old female with end-stage renal disease on hemodialysis secondary to diabetic nephropathy who had ... Read more >>

Case Rep Nephrol Dial (Case reports in nephrology and dialysis)
[2021, 11(3):275-280]

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IgA Nephropathy Secondary to Ipilimumab Use.

Sean C Dougherty, Nisa Desai, Helen P Cathro, Amanda Renaghan,

Ipilimumab is a human monoclonal antibody targeting cytotoxic T-lymphocyte-associated protein 4 approved for the treatment of non-small-cell lung cancer (NSCLC) and other malignancies. Despite a high prevalence of other immune-related adverse events (irAEs), checkpoint inhibitor (CPI)-related nephrotoxicity has been reported less frequently. In this clinical case report, we describe the ... Read more >>

Case Rep Nephrol Dial (Case reports in nephrology and dialysis)
[2021, 11(3):327-333]

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Brevundimonas vesicularis Peritonitis in a Chronic Peritoneal Dialysis Patient.

Vijayakumar Paramasivam, Armando Paez, Ashish Verma, Daniel Landry, Gregory L Braden,

Gram-negative peritonitis in chronic peritoneal dialysis patients is difficult to treat and may result in catheter loss. Brevundimonas vesicularis is a Gram-negative rod bacterium which rarely causes infections in humans. A 41-year-old male receiving continuous cycling peritoneal dialysis for 5 months developed culture-negative peritonitis. He failed initial empiric treatment with ... Read more >>

Case Rep Nephrol Dial (Case reports in nephrology and dialysis)
[2021, 11(3):314-320]

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Methicillin-Resistant Staphylococcus aureus Peritonitis due to Hematogenous Dissemination from Central Venous Catheter in a Maintenance Dialysis Patient.

Gaetano Alfano, Monica Frisina, Niccolò Morisi, Elisabetta Ascione, Francesco Fontana, Giacomo Mori, Caterina Cerami, Francesco Serra, Francesca Cabry, Decenzio Bonucchi, Roberta Gelmini, Giovanni Guaraldi, Riccardo Magistroni, Gianni Cappelli,

<i>Staphylococcus aureus</i> is a Gram-positive bacterium commonly associated with severe infections in hospitalized patients. <i>S. aureus</i> produces many virulence factors leading to local and distant pathological processes. Invasiveness of <i>S. aureus</i> generally induces metastatic infections such as bacteremia, infective endocarditis, osteomyelitis, arthritis, and endophthalmitis. Peritoneal localization from extra-abdominal infection can ... Read more >>

Case Rep Nephrol Dial (Case reports in nephrology and dialysis)
[2021, 11(3):281-285]

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Development of Nivolumab/Ipilimumab-Associated Autoimmune Nephritis during Steroid Therapy.

Ellen Gebauer, Wibke Bechtel-Walz, Christoph Schell, Michelle Erbel, Gerd Walz, Tobias Hermle,

Immunotherapy using immune checkpoint inhibitors revolutionized therapies for a variety of malignancies. Nivolumab, an antibody blocking programmed cell death 1 protein, and ipilimumab that blocks cytotoxic T-lymphocyte-associated protein 4 effectively target tumor cells by disinhibiting the endogenous immune response. At the same time, unrestrained T-cell activation may trigger a range ... Read more >>

Case Rep Nephrol Dial (Case reports in nephrology and dialysis)
[2021, 11(3):270-274]

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Complete Renal Recovery in Pediatric Patient with C3 Glomerulonephritis: A Case Report.

Rabheh Abdul-Aziz, Rong Deng, Lin Liu, Shauna Tarsi, Wayne R Waz, Xiaoyan Wu,

C3 glomerulonephritis (C3GN) is a rare kidney disease resulting from dysregulation of the alternative complement cascade. Without treatment, approximately 70% of affected children and 30-50% of affected adults will develop worsening of proteinuria and progress to end-stage renal disease within 10 years of diagnosis. Here, we describe a 9-year-old Sudanese ... Read more >>

Case Rep Nephrol Dial (Case reports in nephrology and dialysis)
[2021, 11(3):261-269]

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Incoercible Vomiting in a Polycystic (ADPKD) Patient on Peritoneal Dialysis.

Victor Burguera Vion, R Haridian Sosa Barrios, Maria Delgado Yagüe, Milagros Fernández Lucas, Maite E Rivera Gorrín,

Although gastrointestinal symptoms are not uncommon in PD patients due to several causes, such as infusion volume with early satiety, constipation, or peritonitis, sometimes the differential diagnosis is more challenging for nephrologists. We present the case of a woman with end-stage renal disease due to autosomal dominant polycystic kidney disease ... Read more >>

Case Rep Nephrol Dial (Case reports in nephrology and dialysis)
[2021, 11(3):321-326]

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A Case Report of COL4A5 Gene Mutation Alport Syndrome in 2 Native African Children.

Emmanuel Oduware, Nosakhare Joyce Iduoriyekemwen, Michael Ibadin, Henry Aikhionbare,

Alport syndrome is a heterogeneous genetic disease involving the basement membrane of the glomeruli, inner ear, retina, and lens capsule. It typically manifests as progressive glomerulopathy that frequently results in end-stage renal disease, high-tone sensorineural deafness, and ocular abnormalities of anterior lenticonus and yellow and white dots and flecks on ... Read more >>

Case Rep Nephrol Dial (Case reports in nephrology and dialysis)
[2021, 11(3):308-313]

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IgA Nephropathy in a Patient Treated with Adalimumab.

Tonja Mertelj, Nataša Smrekar, Nika Kojc, Jelka Lindič, Damjan Kovač,

Immunoglobulin A (IgA) nephropathy (IgAN) is the most common glomerulonephritis worldwide, characterized by IgA deposits in the glomerular mesangium. It has a progressive nature and can eventually lead to end-stage kidney failure. It can occur as a potential side effect of treatment with tumor necrosis factor alpha antagonist that has ... Read more >>

Case Rep Nephrol Dial (Case reports in nephrology and dialysis)
[2021, 11(2):233-240]

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Extrusion of both Superficial and Deep Cuffs of a Functional Double-Cuff Peritoneal Dialysis Catheter after Significant Weight Loss.

Aravindh S Ganapathy, Myron S Powell, James L Pirkle,

Extrusion of the superficial cuff of a peritoneal dialysis (PD) catheter is an uncommon complication that may be associated with infection or malfunction. However, extrusion of both the superficial and deep cuffs of a double-cuff catheter is rare and uniformly associated with failure and peritonitis. We report a case of ... Read more >>

Case Rep Nephrol Dial (Case reports in nephrology and dialysis)
[2021, 11(2):190-194]

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An Unusual Case of Recurrent Migration of the Peritoneal Dialysis Catheter into the Inguinal Hernia Sac.

Haruna Fukuzaki, Junichiro Nakata, Yuka Shirotani, Yuki Shimizu, Masayuki Maiguma, Nao Nohara, Yusuke Suzuki,

We herein report the first case of a patient with recurrent migration of the peritoneal dialysis (PD) catheter into the inguinal hernia sac. A 58-year-old man suffered from end-stage renal disease due to polycystic kidney disease (PKD). A year before starting PD, a PD catheter was implanted with stepwise initiation ... Read more >>

Case Rep Nephrol Dial (Case reports in nephrology and dialysis)
[2021, 11(2):152-157]

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From Hypokalemic Crisis to Sjogren's Syndrome: A Case Report and Literature Review.

Mansour Mbengue, Cedric Ouanekpone, Seynabou Diagne, Abdou Niang,

Renal involvement occurs in approximately 5% of patients with Sjögren's syndrome (SS). We reported the case of a 20-year-old African woman who was received for paralysis of 4 limbs secondary to hypokalemia. The diagnosis of renal tubular acidosis type 1 complicated by hypokalemia was retained. In the etiologic research of ... Read more >>

Case Rep Nephrol Dial (Case reports in nephrology and dialysis)
[2021, 11(2):147-151]

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Rituximab Treatment in a Patient with Kimura Disease and Membranous Nephropathy: Case Report.

Roald Vissing-Uhre, Alastair Hansen, Susanne Frevert, Ditte Hansen,

Kimura disease (KD) is a chronic, inflammatory disorder with slowly developing subcutaneous tumor-like swellings, often occurring in the head and neck region. KD is diagnosed based on histology, elevated levels of immunoglobulin type E, and increased peripheral eosinophil granulocytes. KD may coexist with glomerular renal diseases, and this case report ... Read more >>

Case Rep Nephrol Dial (Case reports in nephrology and dialysis)
[2021, 11(2):116-123]

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When Paranoia Comes with the Treatment: Psychosis Associated with Tacrolimus Use.

João Machado Nogueira, Maria João Freire, Vanessa Vila Nova, Gustavo Jesus,

Tacrolimus is an immunosuppressive drug frequently used in solid organ transplant recipients. This drug has well-documented neuropsychiatric side effects in the literature, although emergence of psychotic symptoms is rare, being only described in a very few case reports. We present a case of a renal transplant recipient with no prior ... Read more >>

Case Rep Nephrol Dial (Case reports in nephrology and dialysis)
[2021, 11(2):241-246]

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Encapsulating Peritoneal Sclerosis Presenting after Two Donor Kidney Transplantations: A Case Report and Literature Review.

Sasmit Roy, Kyrstin Alexander, Monzurul Hasan Chowdhury, Vijay Vanguri, Kenneth Bodziak,

Encapsulating peritoneal sclerosis is a rare, recurring complication in peritoneal dialysis (PD) patients. With a mortality rate of 51%, it continues to be a therapeutic enigma among clinicians. However, the incidence after kidney transplantation (KT) has rarely been reported. We report a unique case of encapsulating peritoneal sclerosis (EPS), occurring ... Read more >>

Case Rep Nephrol Dial (Case reports in nephrology and dialysis)
[2021, 11(2):204-209]

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Secondary Hemophagocytic Lymphohistiocytosis Complicated by a Cavitary Lung Lesion in a Kidney Transplant Recipient.

Katarzyna Muras-Szwedziak, Maciej Tylski, Anna Masajtis-Zagajewska, Michał Nowicki,

Hemophagocytic lymphohistiocytosis (HLH) is an uncommon life-threatening condition caused by an uncontrolled immunological response. It can develop secondary to malignancies, infections, systemic diseases, and immunosuppression. Multiple risk factors may present in kidney transplant recipients; however, the cases of HLH in this population have been described sparsely. We report a case ... Read more >>

Case Rep Nephrol Dial (Case reports in nephrology and dialysis)
[2021, 11(2):195-203]

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Patiromer in a Patient with Severe Hyperkalemia on Incremental Hemodialysis with 1 Session per Week: A Case Report and Literature Review.

José C De La Flor, Javier Deira, Alexander Marschall, Francisco Valga, Tania Linares, Tania Monzon, Cristina Albarracín, Elisa Ruiz,

Hyperkalemia is common in patients with ESRD, undergoing hemodialysis (HD), and is associated with an increase in hospitalization and mortality. Residual kidney function in long-term dialysis patients is associated with lower morbidity and mortality in HD patients. Although the 2015 National Kidney Foundation-Kidney Disease Outcomes Quality Initiate (NKD-KDOQI) guidelines allow ... Read more >>

Case Rep Nephrol Dial (Case reports in nephrology and dialysis)
[2021, 11(2):158-166]

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Renal Tubular Acidosis Type I with Prominent Hypokalemia and Nephrolithiasis as a Presentation of Sjögren's/Systemic Lupus Erythematosus Disease.

Anna B Basok, Yosef-S Haviv, Boris Rogachev, Marina Vorobiov,

Female patient, suffering from nephrolithiasis, at the age of 32 was admitted for renal colic caused by a stone obstructing UP junction with left hydronephrosis. Nephrostomy was placed, resulting in brisk diuresis. Severe metabolic acidosis with normal anion gap and urine pH of 6.5 was noted. Potassium level dropped to ... Read more >>

Case Rep Nephrol Dial (Case reports in nephrology and dialysis)
[2021, 11(2):247-253]

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Nintedanib-Induced Renal Thrombotic Microangiopathy.

Takeshi Fujita, Hideyuki Nakagawa, Takashi Yokota, Jun Umetani, Daiki Nagawa, Masamichi Nakata, Ikuyo Narita-Kinjo, Reiichi Murakami, Michiko Shimada, Norio Nakamura, Hirofumi Tomita,

Nintedanib is a unique tyrosine kinase inhibitor used to suppress fibrosis in patients with idiopathic pulmonary fibrosis (IPF). Nintedanib has been shown to suppress multiple processes of fibrosis, thereby reducing the rate of lung function decline in patients with IPF. Since vascular endothelial growth factor is one of this agent's ... Read more >>

Case Rep Nephrol Dial (Case reports in nephrology and dialysis)
[2021, 11(2):227-232]

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Antineutrophil Cytoplasmic Autoantibody-Associated Vasculitis with Kidney Involvement in a Patient with AL Amyloidosis.

Brendan L Thoms, Varun Agrawal, Elvira R Umyarova, Pamela C Gibson, Richard J Solomon,

Antineutrophil cytoplasmic autoantibody (ANCA) vasculitis has occasionally been associated with other systemic glomerulonephritis, such as anti-glomerular basement membrane disease. Here, we report the first clinical case of ANCA-associated crescentic glomerulonephritis with AL amyloidosis. An 81-years-old gentleman presented to the hospital with acute kidney injury (serum creatinine 4.7 mg/dL) on a ... Read more >>

Case Rep Nephrol Dial (Case reports in nephrology and dialysis)
[2021, 11(2):183-189]

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Wilms' Tumor in Horseshoe Kidney.

Doan Tien Luu, Nguyen Minh Duc, Thieu-Thi Tra My, Luong Viet Bang, Mai Tan Lien Bang, Nguyen Dinh Van,

Wilms' tumor is the most common malignant kidney tumor found in children. The Horseshoe kidney is the most common renal fusion malformation. However, Wilms' tumor is rarely identified in horseshoe kidney patients. Multimodal treatments in Wilms' tumor can play important roles in increasing the survival rate. In this study, we ... Read more >>

Case Rep Nephrol Dial (Case reports in nephrology and dialysis)
[2021, 11(2):124-128]

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Diuretic Resistance Treated with Low-Dose Hydralazine: A Case Report and Review of the Literature.

Mohammed Alshehri, Christopher Wilcox,

We present a case of severe diuretic resistance and edema from acute cardiorenal syndrome complicating heart failure with preserved ejection fraction (HFpEF) and mild alcoholic liver disease. High doses of intravenous (iv) furosemide plus iv doses of chlorothiazide failed to increase the daily urine output (UV) above 1,500 mL or ... Read more >>

Case Rep Nephrol Dial (Case reports in nephrology and dialysis)
[2021, 11(2):254-260]

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