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Journal Cardiol Res Pract

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Safety and Efficacy of Cryoballoon Ablation of Atrial Fibrillation in relation to the Patients' Age: Results from a Large Real-World Multicenter Observational Project.

Luigi Sciarra, Saverio Iacopino, Giuseppe Arena, Claudio Tondo, Paolo Pieragnoli, Giulio Molon, Massimiliano Manfrin, Antonio Curnis, Antonio Dello Russo, Giovanni Rovaris, Giuseppe Stabile, Leonardo Calò, Gabriele Boscolo, Roberto Verlato,

<h4>Background</h4>The real-world efficacy and safety of atrial fibrillation (AF) ablation in particularly young and elderly patients are still under debate. The aim of the analysis was to investigate the effect of age on the efficacy and safety of cryoballoon ablation (CBA).<h4>Methods</h4>2,534 patients underwent pulmonary vein isolation (PVI) by way of ... Read more >>

Cardiol Res Pract (Cardiology research and practice)
[2021, 2021:9996047]

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Circulating miRNA-29b and Sclerostin Levels Correlate with Coronary Artery Calcification and Cardiovascular Events in Maintenance Hemodialysis Patients.

Jiqing He, Mingjiao Pan, Mingzhi Xu, Ruman Chen,

<h4>Objective</h4>Coronary artery calcification (CAC) is a common complication in end-stage renal disease (ESRD) patients undergoing maintenance hemodialysis (MHD), and the extent of CAC is a predominant predictor of cardiovascular outcomes in MHD patients. In this study, we sought to uncover the relationship between circulating miRNA-29b, sclerostin levels, CAC, and cardiovascular ... Read more >>

Cardiol Res Pract (Cardiology research and practice)
[2021, 2021:9208634]

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Meta-Analysis of Catheter Ablation versus Medical Therapy for Heart Failure Complicated with Atrial Fibrillation.

Xi Zhu, Yingbiao Wu, Zhongping Ning,

Objective:To compare the efficacy of catheter ablation and medical therapy in patients with heart failure and atrial fibrillation. Methods:We searched randomized controlled trials comparing catheter ablation versus medical therapy for heart failure and atrial fibrillation through PubMed, MEDLINE, Embase, Cochrane Clinical Trials Database, Web of Science, and China National Knowledge ... Read more >>

Cardiol Res Pract (Cardiology research and practice)
[2021, 2021:7245390]

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Racial and Socioeconomic Disparities in Out-Of-Hospital Cardiac Arrest Outcomes: Artificial Intelligence-Augmented Propensity Score and Geospatial Cohort Analysis of 3,952 Patients.

Dominique J Monlezun, Alfred T Samura, Ritesh S Patel, Tariq E Thannoun, Prakash Balan,

<h4>Introduction</h4>Social disparities in out-of-hospital cardiac arrest (OHCA) outcomes are preventable, costly, and unjust. We sought to perform the first large artificial intelligence- (AI-) guided statistical and geographic information system (GIS) analysis of a multiyear and multisite cohort for OHCA outcomes (incidence and poor neurological disposition).<h4>Method</h4>We conducted a retrospective cohort analysis ... Read more >>

Cardiol Res Pract (Cardiology research and practice)
[2021, 2021:3180987]

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Applicability of a Novel Wearable Wireless Electrocardiogram Monitoring Device (Spyder) for Arrhythmia Detection in Patients with Suspected Cardiac Arrhythmias.

Do Van Chien, Nguyen Thanh Binh, Nguyen Dung, Pham Truong Son,

<h4>Introduction</h4>In clinical practice, many cardiovascular symptoms can be caused by arrhythmias that are not detected by electrocardiography (ECG) or 24-48 h Holter ECG monitoring.<h4>Aims</h4>To describe the efficacy and applicability of a new device (Spyder) in detecting cardiac arrhythmias with midterm ECG monitoring.<h4>Methods</h4>A descriptive, prospective study was performed on 26 consecutive patients ... Read more >>

Cardiol Res Pract (Cardiology research and practice)
[2021, 2021:8496351]

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Acute Occlusion of the Infarct-Related Artery as a Predictor of Very Long-Term Mortality in Patients with Acute Myocardial Infarction.

Nikola Kos, Ivan Zeljković, Tomislav Krčmar, Karlo Golubić, Fran Šaler, Marijan Erceg, Diana Delić-Brkljačić, Nikola Bulj,

<h4>Aim</h4>The survey's aim was to examine the significance of infarct-related artery (IRA) occlusion (verified angiographically) on very long-term outcomes of patients with acute myocardial infarction, within the STEMI and NSTEMI diagnosis.<h4>Methods</h4>A single-center, nonrandomized, registry-based study on patients treated for acute coronary syndrome with percutaneous coronary intervention between June 2011 and ... Read more >>

Cardiol Res Pract (Cardiology research and practice)
[2021, 2021:6647626]

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Incremental Value of Genotype Bins over the HAS-BLED Score for the Prediction of Bleeding Risk in Warfarin-Treated Patients with Atrial Fibrillation.

Jia Liu, Guanyun Wang, Liu'an Qin, Yangxun Wu, Yuting Zou, Xuyun Wang, Ziqian Wang, Yuyan Wang, Shizhao Zhang, Yuxiao Zhang, Tong Yin,

<h4>Background</h4>This study aimed to analyse the role of the HAS-BLED score with the addition of genotype bins for bleeding risk prediction in warfarin-treated patients with atrial fibrillation (AF).<h4>Methods and results</h4>Consecutive patients with AF on initial warfarin treatment were recruited. For each patient, CYP2C9 <sup><i>∗</i></sup> 3 and VKORC1-1639 A/G genotyping was ... Read more >>

Cardiol Res Pract (Cardiology research and practice)
[2021, 2021:9030005]

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NT-proBNP and Major Adverse Cardiovascular Events in Patients with ST-Segment Elevation Myocardial Infarction Who Received Primary Percutaneous Coronary Intervention: A Prospective Cohort Study.

Zuoan Qin, Yaoyao Du, Quan Zhou, Xuelin Lu, Li Luo, Zhixiang Zhang, Ning Guo, Liangqing Ge,

<h4>Background</h4>The prognostic significance of the amino-terminal fragment of the prohormone brain-type natriuretic peptide (NT-proBNP) in patients with ST-segment elevation myocardial infarction (STEMI) after percutaneous coronary intervention (PCI) has not been fully elucidated. Major adverse cardiovascular events (MACEs) are clinically viable indicators for the accurate, rapid, and safe evaluation of patients ... Read more >>

Cardiol Res Pract (Cardiology research and practice)
[2021, 2021:9943668]

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The Auxiliary Role of Cardiac Magnetic Resonance Feature-Tracking Parameters in the Differentiation between Cardiac Amyloidosis and Constrictive Pericarditis.

Sanaz Asadian, Mahta Farzin, Faezeh Tabesh, Nahid Rezaeian, Hooman Bakhshandeh, Leila Hosseini, Yaser Toloueitabar, Mohammad Mehdi Hemmati Komasi,

<h4>Objectives</h4>Cardiac amyloidosis (CA) and constrictive pericarditis (CP) are described as the differential diagnoses of restrictive hemodynamic alterations of the heart. We aimed to explain cardiac magnetic resonance (CMR) imaging findings (especially feature tracking (FT)) of CA and CP cases and compare them with healthy controls. Moreover, we evaluated the role ... Read more >>

Cardiol Res Pract (Cardiology research and practice)
[2021, 2021:2045493]

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Clinical Characteristics and Long-Term Prognosis of Elderly Valvular Heart Disease Patients with Diabetes Mellitus: Five-Year Experience from a Single-Center Study of Southern China.

Yuan-Feng Liang, Feier Song, Huixia Liu, Jian Liu, Yu-Yuan Zhang, Wei-Dong Lin, Hong-Tao Liao, Hui-Ming Guo, Gary Tse, Fang-Zhou Liu, Zhanyi Lin,

<h4>Background</h4>Diabetes mellitus (DM) is a prognostic marker in elderly patients with cardiovascular diseases, but its predictive value in elderly valvular heart disease (VHD) patients is unclear. This study aimed to investigate the effect of DM on the long-term outcome of elderly VHD patients.<h4>Methods</h4>This single-center, observational study enrolled patients aged 65 ... Read more >>

Cardiol Res Pract (Cardiology research and practice)
[2021, 2021:2558639]

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Value of Follow-Up N-Terminal Probrain Natriuretic Peptide (NT-proBNP) after a Modified Fontan Procedure.

Jianbin Li, Li Ma, Minghui Zou, Wenlei Li, Xinxin Chen, Yanqin Cui, Xiaoyan Hu,

<h4>Objective</h4>To assess the value of N-terminal probrain natriuretic peptide (NT-proBNP) in short-term and long-term follow-up after a modified Fontan procedure.<h4>Methods</h4>We retrospectively enrolled children who had undergone a modified Fontan procedure in the Heart Center of Guangzhou Women and Children's Medical Center from January 2014 to September 2020 and collected data ... Read more >>

Cardiol Res Pract (Cardiology research and practice)
[2021, 2021:3300884]

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The Dose-Dependent Effects of Spironolactone on TGF-β1 Expression and the Vulnerability to Atrial Fibrillation in Spontaneously Hypertensive Rats.

Mirong Tang, Yan Chen, Fuqing Sun, Liangliang Yan,

<h4>Objective</h4>This study tends to assess the dose-dependent effects of spironolactone on TGF-<i>β</i>1 expression, atrial fibrosis, and the vulnerability to atrial fibrillation in spontaneously hypertensive rats (SHRs) and tries to clarify the association of atrial fibrosis with the vulnerability to atrial fibrillation.<h4>Methods</h4>Forty 20-week-old male SHRs were randomly divided into 4 groups ... Read more >>

Cardiol Res Pract (Cardiology research and practice)
[2021, 2021:9924381]

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Quantitative Complexity Theory Used in the Prediction of Head-Up Tilt Testing Outcome.

Paweł Krzesiński, Jacek Marczyk, Bartosz Wolszczak, Grzegorz Gielerak,

<h4>Background</h4>Head-up tilt testing (HUTT), a well-established tool in the diagnosis of vasovagal syncope, is time-consuming, and every provoked vasovagal reaction may result in consolidating the reflex mechanism. Therefore, identification of parameters that could shorten the duration of HUTT and prevent fainting is desirable. Quantitative complexity theory (QCT) may provide holistic ... Read more >>

Cardiol Res Pract (Cardiology research and practice)
[2021, 2021:8882498]

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Correlates of Delayed Initial Contact to Emergency Services among Patients with Suspected ST-Elevation Myocardial Infarction.

Osayi Lawani, Nicholas Gorman, Fiona Gorman, Jiries Ganim, Stefano Sdringola-Maranga,

<h4>Background</h4>Early diagnosis and treatment of a patient displaying symptoms of myocardial ischemia is paramount in preventing detrimental tissue damage, arrhythmias, and death. Patient-related hospital delay is the greatest considerable cause of total delay in treatment for acute myocardial infarction.<h4>Objective</h4>To identify patient characteristics contributing to prehospital delay and ultimately developing health ... Read more >>

Cardiol Res Pract (Cardiology research and practice)
[2021, 2021:8483817]

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Cardiac Outpouchings: Definitions, Differential Diagnosis, and Therapeutic Approach.

Riccardo Scagliola, Gian Marco Rosa, Sara Seitun,

<h4>Background and aims</h4>Cardiac outpouchings encounter a series of distinct congenital or acquired entities (i.e. aneurysms, pseudoaneurysms, diverticula, and herniations), whose knowledge is still poorly widespread in clinical practice. This review aims to provide a comprehensive overview focusing on definition, differential diagnosis, and prognostic outcomes of cardiac outpouchings, as well as ... Read more >>

Cardiol Res Pract (Cardiology research and practice)
[2021, 2021:6792643]

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High-Sensitivity Cardiac Troponin T Is a Risk Factor for Major Adverse Cardiovascular Events and All-Cause Mortality: A 9.5-Year Follow-Up Study.

Xiaona Wang, Peiqi Wang, Ruihua Cao, Xu Yang, Wenkai Xiao, Yun Zhang, Li Sheng, Ping Ye,

<h4>Background</h4>The relationship between high-sensitivity cardiac troponin T (hs-cTnT) and different cardiovascular events has been observed in several large community studies, and the results have been controversial. However, there is currently no cross-sectional or longitudinal follow-up study on hs-cTnT in the Chinese population.<h4>Methods</h4>We analyzed the association of plasma hs-cTnT levels with ... Read more >>

Cardiol Res Pract (Cardiology research and practice)
[2021, 2021:6647987]

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miR-149 Alleviates Ox-LDL-Induced Endothelial Cell Injury by Promoting Autophagy through Akt/mTOR Pathway.

Zhongsheng Zhu, Jinyu Li, Rui Tong, Xiaorong Zhang, Bo Yu,

<h4>Background</h4>Atherosclerosis is a chronic process that takes place in the vascular wall and causes various cardiovascular diseases (CVDs). Micro-RNA-149 (miR-149) mediates many physiological and pathological processes, including atherosclerosis. However, it is unclear about the roles of miR-149 in endothelial injury. Here, we explored the protective effect and related mechanism of ... Read more >>

Cardiol Res Pract (Cardiology research and practice)
[2021, 2021:9963258]

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Mortality and Its Associated Factors among Hospitalized Heart Failure Patients : The Case of South West Ethiopia.

Meiraf Daniel Meshesha, Robel Hussen Kabthymer, Mohammed Mecha Abafogi,

<h4>Background</h4>Hospital case fatality among those with heart failure in Africa ranges from 9% to 12.5%. An integrated approach to identify those who are at high risk and implementing specific treatment strategies is of great importance for a better outcome.<h4>Objective</h4>The aim of this study is to assess the mortality rate and ... Read more >>

Cardiol Res Pract (Cardiology research and practice)
[2021, 2021:5951040]

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The Role of SGLT2 Inhibitors in Heart Failure: A Systematic Review and Meta-Analysis.

Vasiliki Tsampasian, Ranu Baral, Rahul Chattopadhyay, Maciej Debski, Shruti S Joshi, Johannes Reinhold, Marc R Dweck, Pankaj Garg, Vassilios S Vassiliou,

<h4>Aims</h4>Recent randomised controlled trials (RCTs) have shown a significant prognostic benefit of sodium-glucose cotransporter 2 (SGLT2) inhibitors in the cardiovascular (CV) profile of patients with diabetes. This systematic review and meta-analysis aim to provide a concise evaluation of all the available evidence for the use of these agents in patients ... Read more >>

Cardiol Res Pract (Cardiology research and practice)
[2021, 2021:9927533]

Cited: 1 time

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Decreased Spp1 Expression in Acute Myocardial Infarction after Ischemia and Reperfusion Injury.

Ling Li, Jungang Huang, Zongkai Zhao, Zhuzhi Wen, Kang Li, Tianjiao Ma, Lisui Zhang, Junmeng Zheng, Shi Liang,

<h4>Background</h4>With the progress of shock therapy and the establishment and promotion of methods such as thrombolytic therapy and percutaneous coronary intervention (PCI), many tissues and organs have been reperfused after ischemia which may cause even worse disorder called ischemia-reperfusion injury (IRI). mRNAs have been found to have significant impacts on ... Read more >>

Cardiol Res Pract (Cardiology research and practice)
[2021, 2021:3925136]

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Nonmedical Determinants of Congenital Heart Diseases in Children from the Perspective of Mothers: A Qualitative Study in Iran.

Maryam Borjali, Mostafa Amini-Rarani, Mehdi Nosratabadi,

<h4>Introduction</h4>Mortality due to noncommunicable diseases has increased in the world today with the advent of demographic shifts, growing age, and lifestyle patterns in the world, which have been affected by economic and social crises. Congenital heart defects are one of the forms of diseases that have raised infant mortality worldwide. ... Read more >>

Cardiol Res Pract (Cardiology research and practice)
[2021, 2021:6647260]

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ANGPTL4 Attenuates Ang II-Induced Atrial Fibrillation and Fibrosis in Mice via PPAR Pathway.

Xi Zhu, Xiaogang Zhang, Xinpeng Cong, Luoning Zhu, Zhongping Ning,

Atrial fibrillation (AF) is the more significant portion of arrhythmia in clinical practice, with inflammation and fibrosis as its central pathological mechanisms. This study aimed to investigate angiopoietin-like 4 (ANGPTL4) effects on angiotensin II- (Ang II-) induced AF and its related pathophysiological mechanisms. C57BL/6J mice were randomized and divided into ... Read more >>

Cardiol Res Pract (Cardiology research and practice)
[2021, 2021:9935310]

Cited: 1 time

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Left Atrial Appendage Exclusion in Atrial Fibrillation Radiofrequency Ablation during Mitral Valve Surgery: A Single-Center Experience.

C Lavalle, M Straito, E Chourda, S Poggi, G Frati, W Saade, A G M Marullo, M V Mariani, M Magnocavallo, F Miraldi,

<h4>Background</h4>Atrial fibrillation surgical radiofrequency ablation (AFSA) during mitral valve surgery (MVS) has almost completely superseded the Cox-Maze procedure for the treatment of atrial fibrillation.<h4>Methods</h4>We retrospectively analyzed 100 patients who underwent MVS + AFSA in our institution from January 2008 to June 2017. We compared the effectiveness of AFSA in patients who underwent ... Read more >>

Cardiol Res Pract (Cardiology research and practice)
[2021, 2021:9999412]

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Restricted Use of Echocardiography in Suspected Endocarditis during COVID-19 Lockdown: A Multidisciplinary Team Approach.

Adam Hartley, Ahmed El-Sayed, Aula Abbara, Jamie Henderson, Anan Ghazy, Frances Davies, James R Price, Prakash P Punjabi, Jon Anderson, Roberto Casula, Hafiz Naderi, Perviz Asaria, Nilesh Sutaria, Iqbal S Malik, Punam A Pabari, Bushra S Rana,

<h4>Background</h4>Infective endocarditis (IE) is challenging to manage in the COVID-19 lockdown period, in part given its reliance on echocardiography for diagnosis and management and the associated virus transmission risks to patients and healthcare workers. This study assesses utilisation of the endocarditis team (ET) in limiting routine echocardiography, especially transoesophageal echocardiography ... Read more >>

Cardiol Res Pract (Cardiology research and practice)
[2021, 2021:5565200]

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Prognostic Value of Procalcitonin for Morbidity and Mortality in Patients after Cardiac Surgery.

Ahmad Amouzeshi, Farshid Abedi, Mahmoud Zardast, Yaser Rezaeian Bilondi, Zahra Amouzeshi,

<h4>Background</h4>The increased serum procalcitonin (PCT) level in cardiac patients is known as a sign of postoperative complications.<h4>Objective</h4>Considering the importance of predicting the incidence of both complications and mortality caused by coronary artery bypass graft (CABG) surgery, this study was conducted to determine the serum PCT level and its relationship with ... Read more >>

Cardiol Res Pract (Cardiology research and practice)
[2021, 2021:1542551]

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