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Journal Brain Inj

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Neurological manifestations in COVID-19: a systematic review and meta-analysis.

Tzy Harn Chua, Zheyu Xu, Nicolas Kon Kam King,

OBJECTIVE:Following the outbreak of coronavirus 2019 (COVID-19), there is strong evidence of neurological involvement in these patients. We aimed to determine the clinical characteristics of neurological manifestations in COVID-19. METHOD:A systematic review of studies reporting neurological manifestations published between 1 December, 2019 and 11 May, 2020 was performed. Studies were ... Read more >>

Brain Inj (Brain injury)
[2020, :1-20]

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Head impacts in semiprofessional male Soccer players: a prospective video analysis over one season of competitive games.

Hélène Cassoudesalle, Maxime Bildet, Hervé Petit, Patrick Dehail,

Soccer exposes players to head injuries and involves repeated intentional head impacts through heading the ball. Our objective was to investigate the rate of both intentional headers and involuntary head impacts in semiprofessional male soccer players during one season. In this prospective cohort study, we followed 54 men (16-35 years) playing ... Read more >>

Brain Inj (Brain injury)
[2020, :1-6]

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Mediators of quality of life in brain injury.

Kristina Johnson, Nicole Ditchman,

PRIMARY OBJECTIVE:This study examined the mediating role of perceived social support and mastery on quality of life (QOL) among adults with brain injury. RESEARCH DESIGN:An a priori structural model hypothesizing the relationships among symptom severity, mastery, social support, and QOL variables were tested. METHODS AND PROCEDURES:Individuals with brain injury across ... Read more >>

Brain Inj (Brain injury)
[2020, :1-10]

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Sleep disturbances in young adults with childhood traumatic brain injury: relationship with fatigue, depression, and quality of life.

Edith N Botchway, Celia Godfrey, Nicholas P Ryan, Stephen Hearps, Christian L Nicholas, Vicki A Anderson, Cathy Catroppa,

OBJECTIVE:This study assessed the consequences of childhood traumatic brain injury (TBI) on sleep, fatigue, depression, and quality of life (QoL) outcomes and explored the relationships between these variables at 20 years following childhood TBI. PARTICIPANTS:. We followed up 54 young adults with mild, moderate, and severe TBI, and 13 typically ... Read more >>

Brain Inj (Brain injury)
[2020, :1-11]

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Using the health belief model to predict concussion-reporting intentions and behaviour.

Michelle L Weber Rawlins, Cailee E Welch Bacon, Phillip Tomporowski, Jennifer L Gay, Laura L Bierema, Julianne D Schmidt,

PURPOSE:To determine whether Health Belief Model (HBM) factors predict concussion-reporting intentions and behaviour. Methods: Participants completed a cross-sectional survey to measure the HBM constructs of concussion knowledge, perceived susceptibility, perceived severity, perceived benefits, perceived barriers, and cues to action. We also asked participants to indicate their concussion-reporting intentions and behaviourfor ... Read more >>

Brain Inj (Brain injury)
[2020, :1-11]

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Association of seizure co-morbidity with early hospital readmission among traumatic brain injury patients.

Michelle Kwon, Alain Lekoubou, Kinfe G Bishu, Bruce Ovbiagele,

OBJECTIVE:To assess the frequency of seizure co-morbidity and its independent association with 30-day readmission rate among patients hospitalized with traumatic brain injury (TBI) in the United States. METHODS:The data source was the 2014 Nationwide Readmission Database. We included adults (Age ≥18 years) with a primary discharge diagnosis of TBI, identified using ... Read more >>

Brain Inj (Brain injury)
[2020, :1-5]

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Providing equal attention: designing control groups for intensive lifestyle interventions after brain injury.

Shannon Juengst, Evan Rainey, Donna Noorbakhsh, Simon Driver,

PRIMARY OBJECTIVE:Interventions are needed to address chronic health conditions, such as obesity and diabetes, faced by adults with traumatic brain injury (TBI). The objective of this narrative is to present the justification for and an exemplar of an active attention control condition as a needed comparison group in clinical trials ... Read more >>

Brain Inj (Brain injury)
[2020, :1-7]

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Memory in repeat sports-related concussive injury and single-impact traumatic brain injury.

Matthew J Wright, Martin M Monti, Evan S Lutkenhoff, David J Hardy, Pavel Y Litvin, Daniel F Kelly, Kevin Guskiewicz, Robert C Cantu, Paul M Vespa, David A Hovda, Walter D Lopez, Christina Wang, Ronald Swerdloff, Joaquín M Fuster,

Background: Repeat sports-related concussive/subconcussive injury (RC/SCI) is related to memory impairment. Objective & Methods: We sought to determine memory differences between persons with RC/SCI, moderate-to-severe single-impact traumatic brain injury (SI-TBI), and healthy controls. MRI scans from a subsample of participants with SI-TBI were used to identify the neuroanatomical correlates of ... Read more >>

Brain Inj (Brain injury)
[2020, :1-8]

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The effects of aquatic therapy during post-acute neurorehabilitation in patients with severe traumatic brain injury: a preliminary randomized controlled trial.

A Curcio, G Temperoni, Marco Tramontano, S De Angelis, M Iosa, F Mommo, G Cochi, R Formisano,

OBJECTIVE:The primary aim is to verify the effectiveness of an aquatic training (AT) in inpatients with severe Traumatic Brain Injury (sTBI) on balance. The secondary aims are to explore the effects on gait, activities of daily living, and quality of life, comparing to a land-based conventional protocol. METHODS:Two-arm, randomized controlled ... Read more >>

Brain Inj (Brain injury)
[2020, :1-6]

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The relationship between fluid biomarkers and clinical outcomes in sports-related concussions: a systematic review.

Jessica Meyer, Christopher Bartolomei, Adam Sauer, Martha Sajatovic, Christopher M Bailey,

OBJECTIVES:The literature on fluid biomarkers for concussion has primarily focused on comparing athletes with and without a diagnosis of concussion and on examining the relationship between fluid biomarkers and exposure to head trauma. This systematic literature review aims to examine the strength of evidence for fluid biomarkers to be associated ... Read more >>

Brain Inj (Brain injury)
[2020, 34(11):1435-1445]

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Self-efficacy in non-concussed youth: a normative study.

M Paniccia, C Ippolito, S McFarland, J Murphy, N Reed,

OBJECTIVE:In pediatric concussion, there has been a shift to consider how pre-injury profiles, such as self-efficacy, affect the recovery trajectory. The aim of this study was to investigate normal ranges of self-efficacy (overall, academic, social, emotional) in youth and to explore its relationship with the effects of daily stressors, operationalized ... Read more >>

Brain Inj (Brain injury)
[2020, 34(11):1532-1540]

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A scoping review to explore the experiences and outcomes of younger people with disabilities in residential aged care facilities.

Stacey Oliver, Emily Z Gosden-Kaye, Hannah Jarman, Dianne Winkler, Jacinta M Douglas,

OBJECTIVE:In Australia, over 6,000 adults younger than 65 have been inappropriately placed in nursing homes designed to accommodate older adults. The primary aim of this review was to map the literature on the experiences and outcomes of young people with disability who are placed in aged care. METHODS:A scoping review ... Read more >>

Brain Inj (Brain injury)
[2020, 34(11):1446-1460]

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The sibling relationship after acquired brain injury (ABI): perspectives of siblings with ABI and uninjured siblings.

Penelope Analytis, Narelle Warren, Jennie Ponsford,

Primary Objective This study explored the sibling relationship across the lifespan after acquired brain injury (ABI). Research Design A qualitative approach was used to explore the perspectives of siblings with ABI and uninjured siblings. Methods and Procedures Semi-structured interviews with 19 siblings with ABI and 20 uninjured siblings (aged 6-61 years) ... Read more >>

Brain Inj (Brain injury)
[2020, 34(11):1504-1512]

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Cognitive-communication skills and acute outcome following mild traumatic brain injury.

Joanne LeBlanc, Alena Seresova, Andréanne Laberge-Poirier, Sabrina Tabet, José A Correa, Abdulrahman Y Alturki, Mitra Feyz, Elaine de Guise,

PURPOSE:Little is known about cognitive-communication skills post mild traumatic brain injury (mTBI). We aimed to determine how performance on cognitive-communication measures in the acute recovery period relates to early outcome following complicated mTBI. METHOD:Results of language and communication skill measures, demographic and accident-related data, length of stay (LOS), Glasgow Outcome ... Read more >>

Brain Inj (Brain injury)
[2020, 34(11):1472-1479]

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Caregiver burden in familial caregivers and foreign domestic workers of patients with traumatic brain injury in a multi-ethnic Asian population.

Matthew Tay, Keng He Kong,

OBJECTIVE:The purpose of this study was to investigate the prevalence and risk factors associated with caregiver burden in familial caregivers and foreign domestic workers of patients with severe traumatic brain injury. METHODS:A total of 77 caregivers were consecutively recruited, who were either familial caregivers or foreign domestic workers. All caregivers ... Read more >>

Brain Inj (Brain injury)
[2020, 34(11):1513-1517]

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In vivo KPT-350 treatment decreases cortical hyperexcitability following traumatic brain injury.

David Cantu, Danielle Croker, Sharon Shacham, Sharon Tamir, Chris Dulla,

PRIMARY OBJECTIVE:We tested whether KPT-350, a novel selective inhibitor of nuclear export, could attenuate cortical network hyperexcitability, a major risk factor for developing post-traumatic epilepsy (PTE) following traumatic brain injury (TBI). RESEARCH DESIGN:All mice in this study underwent TBI and were subsequently treated with either KPT-350 or vehicle during the ... Read more >>

Brain Inj (Brain injury)
[2020, 34(11):1489-1496]

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Improving communication with patients in post-traumatic amnesia: development and impact of a clinical protocol.

Tessa Hart, Mary Ferraro, Amanda Rabinowitz, Eileen Fitzpatrick DeSalme, Lauren Nelson, Elizabeth Marcy, Stephanie Farm, Lyn Turkstra,

OBJECTIVE:To assess the impact of staff training focused on improved treatment and communication with patients in post-traumatic amnesia (PTA) or other disorders of explicit (declarative) memory. A major aim was to minimize questions demanding recall from explicit memory, e.g., orientation quizzing, and personal/medical history questions, which may produce unreliable information ... Read more >>

Brain Inj (Brain injury)
[2020, 34(11):1518-1524]

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Excessive daytime sleepiness after traumatic brain injury.

Thomas Crichton, Rajiv Singh, Kessewa Abosi-Appeadu, Gary Dennis,

STUDY OBJECTIVES:To identify the prevalence of excessive daytime sleepiness (EDS) in a prospectively recruited patient population with traumatic brain injury (TBI) of mixed severity. Furthermore, the study aimed to assess the relationship between patient factors and EDS. METHOD:One-hundred and eighteen patients with TBI were assessed in a neurorehabilitation clinic after ... Read more >>

Brain Inj (Brain injury)
[2020, 34(11):1525-1531]

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Creating an appropriate adaptation of a healthy lifestyle intervention for people after stroke.

Simon Driver, Evan McShan, Chad Swank, Katherine Grobe, Stephanie Calhoun, Ryan Bailey, Kaye Kramer,

PRIMARY OBJECTIVE:To describe (1) an evidence-based approach to promoting a healthy lifestyle, the Diabetes Prevention Program Group Lifestyle Balance intervention, and (2) our work with input from an Advisory Board of stakeholders to modify the program to meet the unique needs of people post stroke. RESEARCH DESIGN:Community-Based Participatory Research. METHODS ... Read more >>

Brain Inj (Brain injury)
[2020, 34(11):1497-1503]

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Contributions of posttraumatic stress disorder (PTSD) and mild TBI (mTBI) history to suicidality in the INTRuST consortium.

Lauren B Fisher, Jessica Bomyea, Garrett Thomas, Joey C Cheung, Feng He, Sonia Jain, Laura A Flashman, Norberto Andaluz, Raul Coimbra, Mark S George, Gerald A Grant, Christine E Marx, Thomas W McAllister, Lori Shutter, Ariel J Lang, Murray B Stein, Ross D Zafonte,

OBJECTIVE:Mild TBI (mTBI) and posttraumatic stress disorder (PTSD) are independent risk factors for suicidal behaviour (SB). Further, co-occurring mTBI and PTSD increase one's risk for negative health and psychiatric outcomes. However, little research has examined the role of comorbid mTBI and PTSD on suicide risk. METHODS:The present study utilized data ... Read more >>

Brain Inj (Brain injury)
[2020, 34(10):1339-1349]

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The management of depression following traumatic brain injury: A systematic review with meta-analysis.

William Beedham, Antonio Belli, Sathana Ingaralingam, Sayeed Haque, Rachel Upthegrove,

BACKGROUND:Traumatic brain injury (TBI) is prevalent. Declining mortality has led to increasing survivors with chronic sequalae, including depression. With a lack of guidelines, this review aims to provide a comprehensive, evidence-based summary of the management of depression following TBI. METHODS:Systematic searches were conducted for quasi-experimental and randomized controlled trials (RCTs) ... Read more >>

Brain Inj (Brain injury)
[2020, 34(10):1287-1304]

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First case of delayed traumatic intracerebral hemorrhage in a patient with undiagnosed factor XI deficiency: diagnosis and management review.

Eduardo E Espinosa-Rodríguez, María López-Gutiérrez, Gloria Tresserras-Giné, Nuria Pesa-Vendrell, Melcior Martínez-Pérez,

Factor XI (FXI) deficiency, also known as hemophilia C, is included in the rare bleeding disorders (RBDs). It is distinct from other coagulation factor deficiencies because it rarely presents as spontaneous hemorrhage, but rather as bleeding after trauma or surgery; in addition, the severity of bleeding does not correlate with ... Read more >>

Brain Inj (Brain injury)
[2020, 34(11):1541-1547]

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Pediatric minor head trauma in Brazil and external validation of PECARN rules with a cost-effectiveness analysis.

Leopoldo Mandic Ferreira Furtado, José Aloysio da Costa Val Filho, André Ribeiro Dos Santos, Raísa Furfuro E Sá, Bruno Lacerda Sandes, Yangpol Hon, Eustáquio Claret Dos Santos Júnior, Rodrigo Moreira Faleiro,

BACKGROUND:Pediatric minor head trauma approaches aim to ensure the absence of traumatic brain lesions, minimize ionizing radiation, and enhance cost control. We evaluated the applicability and cost-effectiveness of the Pediatric Emergency Care Applied Research Network (PECARN) rules after head trauma and rationalize the use of head computed tomography (CT) scans. ... Read more >>

Brain Inj (Brain injury)
[2020, 34(11):1467-1471]

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The relationship of religious coping strategies and family harmony with caregiver burden for family members of patients with stroke.

Duygu Kes, Tugba Aydin Yildirim,

AIM:Patients with stroke experience various challenges such as motor and cognitive and sensory problems, which can increase the caregiver burden of family members in long-term care. Understanding the factors related to caregiver burden is important to develop strategies to support informal caregivers. Therefore, this study aimed to examine the relationship ... Read more >>

Brain Inj (Brain injury)
[2020, 34(11):1461-1466]

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The integrated functions of the cardiac autonomic and vestibular/oculomotor systems in adolescents following severe traumatic brain injury and typically developing controls.

Gilad Sorek, Isabelle Gagnon, Kathryn Schneider, Mathilde Chevignard, Nurit Stern, Yahaloma Fadida, Liran Kalderon, Sharon Shaklai, Michal Katz-Leurer,

INTRODUCTION:The cardiac autonomic control system (CACS) is frequently impaired post-traumatic brain injury (TBI). However, the prevalence of vestibular/oculomotor impairment is less studied. These two systems interact during position change and contribute to blood-pressure regulation through the vestibulo-sympathetic reflex. Aim: To assess the CACS, the vestibular/oculomotor systems and their integrative function ... Read more >>

Brain Inj (Brain injury)
[2020, 34(11):1480-1488]

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