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Barriers, facilitators, preferences and expectations of joint protection programmes for patients with hand arthritis: a cross-sectional survey.

Pavlos Bobos, Joy MacDermid, Christina Ziebart, Eleni Boutsikari, Emily Lalone, Louis Ferreira, Ruby Grewal,

<h4>Objectives</h4>The objective of this survey was to investigate the barriers, facilitators, expectations and patient preferences regarding joint protection (JP) programmes in people with hand arthritis.<h4>Design</h4>Cross-sectional survey.<h4>Setting</h4>Tertiary clinic.<h4>Participants</h4>Patients with hand arthritis: osteoarthritis, rheumatoid arthritis, psoriatic arthritis and other forms of arthritis.<h4>Primary and secondary outcome measures</h4>This study used a survey among people ... Read more >>

BMJ Open (BMJ open)
[2021, 11(1):e041935]

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Is the Thoughts and Health programme feasible in the context of Swedish schools? A quasi-experimental controlled trial study protocol.

Carl Wikberg, Pia Augustsson, Gudny Sveinsdottir, W Edward Craighead, Erikur Örn Arnarson, Ina Marteinsdottir, Josefine L Lilja,

<h4>Introduction</h4>Clinical depression is a substantial problem among adolescents, increasing significantly at about age 15 years. It causes impairment in social, academic and familial relationships, as well as ongoing cognitive and emotional difficulties for the individual. A study in Iceland demonstrated that a cognitive-behavioural, developmentally based intervention programme, 'Thoughts and Health', ... Read more >>

BMJ Open (BMJ open)
[2021, 11(1):e040374]

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Multicentre, randomised trial of preterm infants receiving caffeine and less invasive surfactant administration compared with caffeine and early continuous positive airway pressure (CaLI trial): study protocol.

Felix Ines, Shandee Hutson, Katherine Coughlin, Andrew Hopper, Anamika Banerji, Cherry Uy, Neil Finer, Wade Rich, Ana Morales, Jane Steen, Anup C Katheria,

<h4>Introduction</h4>Respiratory distress syndrome (RDS) or surfactant deficiency occurs primarily in premature infants resulting in composite outcomes of death or bronchopulmonary dysplasia. Initial management strategies for preterm infants with RDS includes early initiation of continuous positive airway pressure (CPAP) and titration of fractional inspired oxygen (FiO<sub>2</sub>), and may include the use ... Read more >>

BMJ Open (BMJ open)
[2021, 11(1):e038343]

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Randomised controlled trial to assess efficacy of pelvic floor muscle training on bowel symptoms after low anterior resection for rectal cancer: study protocol.

Anne Asnong, André D'Hoore, Marijke Van Kampen, Nele Devoogdt, An De Groef, Kim Sterckx, Hilde Lemkens, Albert Wolthuis, Yves Van Molhem, Bart Van Geluwe, Lynn Debrun, Inge Geraerts,

<h4>Introduction</h4>Radical surgery after a total mesorectal excision (TME) for rectal cancer often results in a significant decrease in the patient's quality of life, due to functional problems such as bowel, urinary and sexual dysfunction. The effect of pelvic floor muscle training (PFMT) on these symptoms has been scarcely investigated. We ... Read more >>

BMJ Open (BMJ open)
[2021, 11(1):e041797]

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Does the UKCAT predict performance in medical and dental school? A systematic review.

Rachel Greatrix, Sandra Nicholson, Susan Anderson,

<h4>Objectives</h4>For the first time, this systematic review provides a summary of the literature exploring the relationship between performance in the UK Clinical Aptitude Test (UKCAT) and assessments in undergraduate medical and dental training.<h4>Design</h4>In accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis, relevant studies were identified through systematic ... Read more >>

BMJ Open (BMJ open)
[2021, 11(1):e040128]

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Sexual behaviour patterns and STI risk: results of a cluster analysis among men who have sex with men in Portugal.

Karel Blondeel, Sonia Dias, Martina Furegato, Armando Seuc, Ana Gama, Ricardo Fuertes, Luís Mendão, Marleen Temmerman, Igor Toskin,

<h4>Objectives</h4>Portugal has the highest HIV incidence rate in Western Europe. The proportion assigned to sexual contact between men recently increased to more than 30% of all HIV infections. Men who have sex with men (MSM) are vulnerable to the acquisition of other sexually transmitted infections (STIs), increasing the per-contact risk ... Read more >>

BMJ Open (BMJ open)
[2021, 11(1):e033290]

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Predictive study of tuberculosis incidence by time series method and Elman neural network in Kashgar, China.

Yanling Zheng, Xueliang Zhang, Xijiang Wang, Kai Wang, Yan Cui,

<h4>Objectives</h4>Kashgar, located in Xinjiang, China has a high incidence of tuberculosis (TB) making prevention and control extremely difficult. In addition, there have been very few prediction studies on TB incidence here. We; therefore, considered it a high priority to do prediction analysis of TB incidence in Kashgar, and so provide ... Read more >>

BMJ Open (BMJ open)
[2021, 11(1):e041040]

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Research Evaluation Alongside Clinical Treatment in COVID-19 (REACT COVID-19): an observational and biobanking study.

Hannah Burke, Anna Freeman, Ahilanandan Dushianthan, Michael Celinski, James Batchelor, Hang Phan, Florina Borca, Christopher Kipps, Gareth J Thomas, Saul N Faust, Natasha Sheard, Sarah Williams, Paul Fitzpatrick, Dónal Landers, Tom Wilkinson,

<h4>Introduction</h4>The COVID-19 pandemic caused by SARS-CoV-2 places immense worldwide demand on healthcare services. Earlier identification of patients at risk of severe disease may allow intervention with experimental targeted treatments, mitigating the course of their disease and reducing critical care service demand.<h4>Methods and analysis</h4>This prospective observational study of patients tested or ... Read more >>

BMJ Open (BMJ open)
[2021, 11(1):e043012]

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Cohort profile: the St Vincent's Melbourne Arthroplasty Outcomes (SMART) Registry, a pragmatic prospective database defining outcomes in total hip and knee replacement patients.

Daniel Gould, Sharmala Thuraisingam, Cade Shadbolt, Josh Knight, Jesse Young, Chris Schilling, Peter F Choong, Michelle M Dowsey,

<h4>Purpose</h4>The St Vincent's Melbourne Arthroplasty Outcomes (SMART) Registry is an institutional clinical registry housed at a tertiary referral hospital in Australia. The SMART Registry is a pragmatic prospective database, which was established to capture a broad range of longitudinal clinical and patient-reported outcome data to facilitate collaborative research that will ... Read more >>

BMJ Open (BMJ open)
[2021, 11(1):e040408]

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Automated detection of patients with dementia whose symptoms have been identified in primary care but have no formal diagnosis: a retrospective case-control study using electronic primary care records.

Elizabeth Ford, Joanne Sheppard, Seb Oliver, Philip Rooney, Sube Banerjee, Jackie A Cassell,

<h4>Objectives</h4>UK statistics suggest only two-thirds of patients with dementia get a diagnosis recorded in primary care. General practitioners (GPs) report barriers to formally diagnosing dementia, so some patients may be known by GPs to have dementia but may be missing a diagnosis in their patient record. We aimed to produce ... Read more >>

BMJ Open (BMJ open)
[2021, 11(1):e039248]

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Predictive utility of the Activity Measure for Post-Acute Care '6-Clicks' short forms on discharge disposition and effect on readmissions: a retrospective observational cohort study.

Melissa Harry, Theo Woehrle, Colleen Renier, Margaret Furcht, Michelle Enockson,

<h4>Objectives</h4>To evaluate the predictive utility of the Activity Measure for Post-Acute Care '6-Clicks' daily activity and basic mobility functional assessment short forms on inpatient discharge to home compared with skilled nursing facilities, including by diagnostic group (trauma injury, major lower joint replacement/reattachment, spinal fusion excluding cervical), as well as assess ... Read more >>

BMJ Open (BMJ open)
[2021, 11(1):e044278]

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Observational study investigating the prevalence of asymptomatic stage B heart failure in patients with type 2 diabetes who are not known to have coronary artery disease.

Mon Myat Oo, Isaiah Tan Chung Zhen, Kee Seong Ng, Kok Leng Tan, Alexander T B Tan, Shireene Ratna Vethakkan, R Jeyakantha A/L Ratnasingam, Kok Han Chee,

<h4>Objective</h4>To identify the prevalence of stage B heart failure (SBHF) in patients with type 2 diabetes mellitus (T2DM) with no history of cardiovascular disease (CVD).<h4>Design</h4>Observational study.<h4>Setting</h4>A single-centre study in which eligible patients were recruited from T2DM clinic. Following consent, patients completed a questionnaire and underwent physical examinations. Patients had blood ... Read more >>

BMJ Open (BMJ open)
[2021, 11(1):e039869]

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Evaluating the feasibility and acceptability of a co-design approach to developing an integrated model of care for people with multi-morbid COPD in rural Nepal: a qualitative study.

Uday Narayan Yadav, Jane Lloyd, Kedar Prasad Baral, Narendra Bhatta, Suresh Mehata, Mark Harris,

<h4>Objective</h4>To understand the feasibility and acceptability of a co-design approach to developing an integrated model of healthcare for people with multi-morbid chronic obstructive pulmonary disease (COPD) in rural Nepal.<h4>Settings</h4>A rural setting of Nepal.<h4>Participants</h4>Data collection included five video recordings, five key informant interviews and observation notes from a final co-design workshop ... Read more >>

BMJ Open (BMJ open)
[2021, 11(1):e045175]

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Which Exercise for Low Back Pain? (WELBack) trial predicting response to exercise treatments for patients with low back pain: a validation randomised controlled trial protocol.

Luciana G Macedo, Paul W Hodges, Geoff Bostick, Mark Hancock, Maude Laberge, Steven Hanna, Greg Spadoni, Anita Gross, Julia Schneider,

<h4>Introduction</h4>Exercise therapy is the most recommended treatment for chronic low back pain (LBP). Effect sizes for exercises are usually small to moderate and could be due to the heterogeneity of people presenting with LBP. Thus, if patients could be better matched to exercise based on individual factors, then the effects ... Read more >>

BMJ Open (BMJ open)
[2021, 11(1):e042792]

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Effectiveness of pretend medical play in improving children's health outcomes and well-being: a systematic review.

Aneesa Abdul Rashid, Ai Theng Cheong, Ranita Hisham, Nurainul Hana Shamsuddin, Dalila Roslan,

<h4>Background</h4>The healthcare setting is stressful for many people, especially children. Efforts are needed to mitigate children's healthcare-related anxiety. Medical play using the Teddy Bear Hospital (TBH) concept can expose children to healthcare settings and help them develop positive experiences in these settings. In this role-playing game, children bring their soft ... Read more >>

BMJ Open (BMJ open)
[2021, 11(1):e041506]

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Impact of transcatheter aortic valve implantation on left ventricular function recovery, mass regression and outcome in patients with aortic stenosis: protocol of the TAVI-NOR prospective study.

Abukar Mohamed Ali, Daanyaal Wasim, Kjetil Halvorsen Løland, Svein Rotevatn, Øyvind Bleie, Sahrai Saeed,

<h4>Introduction</h4>Transcatheter aortic valve implantation (TAVI) is a widely used treatment option as an alternative to surgical aortic valve replacement in patients with severe aortic stenosis (AS) at high or intermediate surgical risk. TAVI improves symptoms, induces reverse left ventricular (LV) remodelling and increases overall survival. However, a careful patient selection ... Read more >>

BMJ Open (BMJ open)
[2021, 11(1):e039961]

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Association of smoking reduction and mortality: protocol for a systematic review and meta-analysis of longitudinal observational studies.

Henri-Jean Aubin, Laetitia Ali Oicheih, Sonia Gabriel, Ivan Berlin,

<h4>Introduction</h4>Strong evidence shows that smoking cessation decreases mortality. Much less is known regarding the association between reduction in cigarettes per day (CPD) and mortality. The primary aim of this systematic review is to compare the mortality risk between smokers achieving a sustained reduction of CPD and smokers maintaining their smoking ... Read more >>

BMJ Open (BMJ open)
[2021, 11(1):e039483]

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Development of unmanned aerial vehicle (UAV) networks delivering early defibrillation for out-of-hospital cardiac arrests (OHCA) in areas lacking timely access to emergency medical services (EMS) in Germany: a comparative economic study.

Jan Bauer, Dieter Moormann, Reinhard Strametz, David A Groneberg,

<h4>Objectives</h4>This study wants to assess the cost-effectiveness of unmanned aerial vehicles (UAV) equipped with automated external defibrillators (AED) in out-of-hospital cardiac arrests (OHCA). Especially in rural areas with longer response times of emergency medical services (EMS) early lay defibrillation could lead to a significant higher survival in OHCA.<h4>Participants</h4>3296 emergency medical ... Read more >>

BMJ Open (BMJ open)
[2021, 11(1):e043791]

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Investigating online psychological treatment for adolescents with a visible difference in the Dutch YP Face IT study: protocol of a randomised controlled trial.

Marije van Dalen, Suzanne G M A Pasmans, Marie-Louise Aendekerk, Irene Mathijssen, Maarten Koudstaal, Reinier Timman, Heidi Williamson, Manon Hillegers, Elisabeth M W J Utens, Jolanda Okkerse,

<h4>Introduction</h4>This paper outlines the study protocol for the Dutch Young People (YP) Face IT Study. Adolescents with a visible difference (ie, disfigurement) often experience challenging social situations such as being stared at, receiving unwanted questions or being teased. As a consequence, some of these adolescents experience adverse psychosocial outcomes and ... Read more >>

BMJ Open (BMJ open)
[2021, 11(1):e041449]

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Estimating the return on investment of the Bureau of Tobacco Free Florida tobacco control programme from 1999 to 2015.

James Nonnemaker, Anna J MacMonegle, Nathan Mann, Robyn Woodlea, Jennifer Duke, Lauren Porter,

<h4>Objective</h4>To assess the return on investment (ROI) of the Florida tobacco control programme, the Bureau of Tobacco Free Florida (BTFF), in terms of healthcare expenditure savings and mortality cost saved as a result of reduced mortality due to the programme from 1999 to 2015.<h4>Methods</h4>We use a synthetic control method to ... Read more >>

BMJ Open (BMJ open)
[2021, 11(1):e040012]

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Investigating the use of a two-stage attention-aware convolutional neural network for the automated diagnosis of otitis media from tympanic membrane images: a prediction model development and validation study.

Yuexin Cai, Jin-Gang Yu, Yuebo Chen, Chu Liu, Lichao Xiao, Emad M Grais, Fei Zhao, Liping Lan, Shengxin Zeng, Junbo Zeng, Minjian Wu, Yuejia Su, Yuanqing Li, Yiqing Zheng,

<h4>Objectives</h4>This study investigated the usefulness and performance of a two-stage attention-aware convolutional neural network (CNN) for the automated diagnosis of otitis media from tympanic membrane (TM) images.<h4>Design</h4>A classification model development and validation study in ears with otitis media based on otoscopic TM images. Two commonly used CNNs were trained and ... Read more >>

BMJ Open (BMJ open)
[2021, 11(1):e041139]

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Correction: Study protocol: a prospective cohort on non-communicable diseases among primary healthcare users living in Kosovo (KOSCO).

BMJ Open (BMJ open)
[2021, 11(1):1]

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COVID-19 among the inhabitants of the slums in the city of Buenos Aires: a population-based study.

Alejandro Macchia, Daniel Ferrante, Gabriel Battistella, Javier Mariani, Fernán González Bernaldo de Quirós,

<h4>Objective</h4>To summarise the unfolding of the COVID-19 epidemic among slum dwellers and different social strata in the city of Buenos Aires during the first 20 weeks after the first reported case.<h4>Design</h4>Observational study using a time-series analysis. Natural experiment in a big city.<h4>Setting</h4>Population of the city of Buenos Aires and the ... Read more >>

BMJ Open (BMJ open)
[2021, 11(1):e044592]

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Association between objectively measured body composition, sleep parameters and physical activity in preschool children: a cross-sectional study.

Justyna Wyszyńska, Piotr Matłosz, Muhammad Asif, Agnieszka Szybisty, Paweł Lenik, Katarzyna Dereń, Artur Mazur, Jarosław Herbert,

<h4>Objective</h4>Associations between self-reported sleep duration and obesity indices in children are well recognised; however, there are no studies on associations between objectively measured other sleep parameters and physical activity with body composition in preschoolers. Therefore, the aim of this study was to determine the associations between sleep parameters and moderate-to-vigorous ... Read more >>

BMJ Open (BMJ open)
[2021, 11(1):e042669]

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Diagnostic and predictive accuracy of the Clinical Frailty Scale among hospitalised older medical patients: a systematic review and meta-analysis protocol.

Aoife Leahy, Margaret O'Connor, Jennifer Condon, Sarah Heywood, Elaine Shanahan, Catherine Peters, Rose Galvin,

<h4>Introduction</h4>Frailty is a common condition affecting older adults and is associated with increased mortality and adverse outcomes. Identification of older adults at risk of adverse outcomes is central to subsequent resource planning and targeted interventions. This systematic review and meta-analysis will examine the: (1) diagnostic accuracy of the Clinical Frailty ... Read more >>

BMJ Open (BMJ open)
[2021, 11(1):e040765]

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