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Journal Ann. Surg. Oncol.

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ASO Author Reflections: Estimating the Prevalence of Pseudomyxoma Peritonei in Europe Using a Novel Statistical Method.

Kjersti Flatmark, Faheez Mohamed,

Ann. Surg. Oncol. (Annals of surgical oncology)
[2020, :]

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ASO Author Reflections: A Standard Set of Value-Based Patient-Centered Outcomes for Pancreatic Carcinoma: An International Delphi Survey.

Patrick Pessaux, Zineb Cherkaoui,

Ann. Surg. Oncol. (Annals of surgical oncology)
[2020, :]

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ASO Author Reflections: Radiopathomics Strategy of Combing Multi-scale Tumor Information on Pretreatment to Predict the Pathologic Response to Neoadjuvant Therapy.

Jie Tian, Xinjuan Fan, Ruihua Xu, Ying-Shi Sun, Guanyu Yang,

Ann. Surg. Oncol. (Annals of surgical oncology)
[2020, :]

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Breast Cancer Surgery Decision Role Perceptions and Choice of Surgery.

Lily Gutnik, Chelsea McCarty Allen, Angela P Presson, Cindy B Matsen,

BACKGROUND:Retrospective studies have reported that breast cancer patients who perceived more personal responsibility for the surgery decision were more likely to undergo aggressive surgery. We examined this in a prospective study. METHODS:100 newly diagnosed breast cancer patients identified their decision- making role using the Patient Preference Scale. Chart review captured ... Read more >>

Ann. Surg. Oncol. (Annals of surgical oncology)
[2020, :]

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A Novel Classification of Intrahepatic Cholangiocarcinoma Phenotypes Using Machine Learning Techniques: An International Multi-Institutional Analysis.

Diamantis I Tsilimigras, J Madison Hyer, Anghela Z Paredes, Adrian Diaz, Dimitrios Moris, Alfredo Guglielmi, Luca Aldrighetti, Matthew Weiss, Todd W Bauer, Sorin Alexandrescu, George A Poultsides, Shishir K Maithel, Hugo P Marques, Guillaume Martel, Carlo Pulitano, Feng Shen, Olivier Soubrane, Bas Groot Koerkamp, Itaru Endo, Timothy M Pawlik,

INTRODUCTION:Patients with intrahepatic cholangiocarcinoma (ICC) generally have a poor prognosis, yet there can be heterogeneity in the patterns of presentation and associated outcomes. We sought to identify clusters of ICC patients based on preoperative characteristics that may have distinct outcomes based on differing patterns of presentation. METHODS:Patients undergoing curative-intent resection of ... Read more >>

Ann. Surg. Oncol. (Annals of surgical oncology)
[2020, :]

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Prognostic Impact of Budding Grade in Patients With Residual Liver Recurrence of Colorectal Cancer After Initial Hepatectomy.

Takuji Noro, Makoto Nishikawa, Mayumi Hoshikawa, Takahiro Einama, Suefumi Aosasa, Yoshiki Kajiwara, Yoshihisa Yaguchi, Koichi Okamoto, Eiji Shinto, Hironori Tsujimoto, Kazuo Hase, Hideki Ueno, Junji Yamamoto,

BACKGROUND:Many patients undergoing hepatectomy for colorectal liver metastases (CRLM) experience recurrence. However, no criteria for screening candidates to undergo repeat hepatectomy (RH) for CRLM have been established. Budding, one form by which colorectal carcinoma malignancies are expressed, is a new pathologic index. This study aimed to analyze prognostic factors, including ... Read more >>

Ann. Surg. Oncol. (Annals of surgical oncology)
[2020, :]

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Extranodal Tumor Deposits in the Axillary Fat Indicate the Need for Axillary Dissection Among T1-T2cN0 Patients with Positive Sentinel Nodes.

Anita Mamtani, Andrea V Barrio, Debra A Goldman, Hannah Y Wen, Alain Vincent, Monica Morrow,

BACKGROUND:The American College of Surgeons Oncology Group (ACOSOG) Z0011 trial demonstrated the safety of omitting axillary lymph node dissection (ALND) in T1-T2cN0 patients with fewer than three positive sentinel nodes (SLNs) undergoing breast-conservation therapy. While microscopic extracapsular extension (mECE) > 2 mm is associated with increased nodal burden, the significance of extranodal tumor ... Read more >>

Ann. Surg. Oncol. (Annals of surgical oncology)
[2020, :]

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Tumor Immune Profiling-Based Neoadjuvant Immunotherapy for Locally Advanced Melanoma.

Lauren S Levine, Kelly M Mahuron, Katy K Tsai, Clinton Wu, Daiva M Mattis, Mariela L Pauli, Arielle Oglesby, James C Lee, Matthew H Spitzer, Matthew F Krummel, Alain P Algazi, Michael D Rosenblum, Michael Alvarado, Adil I Daud,

BACKGROUND:The frequency of "exhausted" or checkpoint-positive (PD-1+CTLA-4+) cytotoxic lymphocytes (Tex) in the tumor microenvironment is associated with response to anti-PD-1 therapy in metastatic melanoma. The current study determined whether pretreatment Tex cells in locally advanced melanoma predicted response to neoadjuvant anti-PD-1 blockade. METHODS:Pretreatment tumor samples from 17 patients with locally ... Read more >>

Ann. Surg. Oncol. (Annals of surgical oncology)
[2020, :]

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The Role of Cardiopulmonary Exercise Testing as a Risk Assessment Tool in Patients Undergoing Oesophagectomy: A Systematic Review and Meta-analysis.

Jonathan Sivakumar, Harry Sivakumar, Matthew Read, Rhona C F Sinclair, Chistopher P Snowden, Michael W Hii,

INTRODUCTION:Cardiopulmonary exercise testing (CPET) is an objective method of assessing functional capacity to meet the metabolic demands of surgery and has been adopted as a preoperative risk-stratification tool for patients undergoing major procedures. The two main measures are the peak rate of oxygen uptake during exercise ([Formula: see text]O2peak) and ... Read more >>

Ann. Surg. Oncol. (Annals of surgical oncology)
[2020, :]

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ASO Author Reflections: Tumor Immune Profiling-Based Neoadjuvant Immunotherapy for Locally Advanced Melanoma.

Kelly M Mahuron, Lauren S Levine, Adil I Daud,

Ann. Surg. Oncol. (Annals of surgical oncology)
[2020, :]

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Estimating the Prevalence of Pseudomyxoma Peritonei in Europe Using a Novel Statistical Method.

Thale Dawn J H Patrick-Brown, Norman John Carr, David M Swanson, Stein Larsen, Faheez Mohamed, Kjersti Flatmark,

BACKGROUND:The determination of the incidence and prevalence of rare diseases is important for economists and health-care providers. Pseudomyxoma peritonei (PMP) is a rare, slow-growing abdominal cancer that represents a substantial burden on both patients and health-care systems. The incidence rate was previously approximated at 1-2 people per million per year; ... Read more >>

Ann. Surg. Oncol. (Annals of surgical oncology)
[2020, :]

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ASO Author Reflections: Limiting Axillary Surgery for Microinvasive Breast Cancer.

Ted A James, Betty Fan,

Ann. Surg. Oncol. (Annals of surgical oncology)
[2020, :]

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Surgery for Gastric Remnant Cancer Results in Similar Overall Survival Rates Compared with Primary Gastric Cancer: A Propensity Score-Matched Analysis.

Christian Galata, Ulrich Ronellenfitsch, Christel Weiß, Susanne Blank, Christoph Reißfelder, Julia Hardt,

BACKGROUND:The purpose of this study was to investigate clinical features, prognostic factors, and overall survival (OS) in surgical patients with gastric remnant cancer (GRC). METHODS:A retrospective analysis of patients with gastrectomy for pT1-4 gastric cancer between October 1972 and February 2014 at our institution was performed. Clinical characteristics were compared ... Read more >>

Ann. Surg. Oncol. (Annals of surgical oncology)
[2020, :]

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Selecting Node-Positive Patients for Axillary Downstaging with Neoadjuvant Chemotherapy.

Giacomo Montagna, Anita Mamtani, Andrea Knezevic, Edi Brogi, Andrea V Barrio, Monica Morrow,

BACKGROUND:Axillary lymph node dissection (ALND) can be avoided in node-positive patients who receive neoadjuvant chemotherapy (NAC) if three or more negative sentinel lymph nodes (SLNs) are retrieved. We evaluate how often node-positive patients avoid ALND with NAC, and identify predictors of identification of three or more SLNs and of nodal ... Read more >>

Ann. Surg. Oncol. (Annals of surgical oncology)
[2020, :]

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Center Experience Affects Liver Transplant Outcomes in Patients with Hilar Cholangiocarcinoma.

Toshihiro Kitajima, Taizo Hibi, Dilip Moonka, Gonzalo Sapisochin, Marwan S Abouljoud, Shunji Nagai,

BACKGROUND:Based on favorable outcomes reported by experienced centers, perihilar cholangiocarcinoma (Ph-CCA) has become an accepted indication for liver transplantation (LT). What is less clear is if the reported outcomes have been reproduced nationwide in the US. OBJECTIVE:The aim of this study was to evaluate post-transplant outcomes in patients with Ph-CCA ... Read more >>

Ann. Surg. Oncol. (Annals of surgical oncology)
[2020, :]

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ASO Author Reflections: Middle Hepatic Vein Anatomy for Safe Dissemination of Laparoscopic Segment 8 Resection.

Satoshi Ogiso, Satoru Seo,

Ann. Surg. Oncol. (Annals of surgical oncology)
[2020, :]

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Laparoscopic Central Bisectionectomy Including Resection of the Segment 7 Using the Extrahepatic Glissonean Approach and Hepatic Vein Guidance.

Rawisak Chanwat, Tatsana Uthaithammarat, Sar Thaithaworn,

BACKGROUND:Certain variations in liver anatomy can aid in parenchymal-preserving hepatectomy.1,2 Inferior right hepatic vein (IRHV) is an accessory vein in the right side of liver draining segment 6.2 We present a case of 67-year-old man with HBV cirrhosis. One HCC in segment 7 abutting the right hepatic vein (RHV) and ... Read more >>

Ann. Surg. Oncol. (Annals of surgical oncology)
[2020, :]

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Minimally Invasive Ivor-Lewis Esophagectomy for Esophageal Cancer After Gastric Bypass.

Michael Latzko, Bestoun Ahmed, Ziad Awad,

The increasing prevalence of morbid obesity in the United States has been accompanied by a concomitant rise in bariatric surgery to help combat the epidemic. The relationship between obesity and certain cancers, such as esophageal adenocarcinoma, is well established. The need for minimally invasive techniques to treat esophageal cancer in ... Read more >>

Ann. Surg. Oncol. (Annals of surgical oncology)
[2020, :]

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2020 Annual Meeting Official Proceedings, Volume XXI.

Ann. Surg. Oncol. (Annals of surgical oncology)
[2020, :]

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Comparison of Surgical Outcomes of Robotic and Conventional Approaches in Patients with Pre- and Poststyloid Parapharyngeal Space Tumors.

Jae-Yol Lim, Young Min Park, Min Seok Kang, Da Hee Kim, Eun Chang Choi, Se-Heon Kim, Yoon Woo Koh,

BACKGROUND:Benefits and drawbacks of robotic surgical approaches for parapharyngeal space (PPS) tumors remain undetermined. The purpose of this study is to compare surgical outcomes of PPS tumor patients who underwent robotic surgery with those of patients who received conventional surgical treatment. PATIENTS AND METHODS:We retrospectively analyzed clinicopathologic data from 136 ... Read more >>

Ann. Surg. Oncol. (Annals of surgical oncology)
[2020, :]

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Quality-of-Life and Surgical Outcomes for Breast Cancer Patients Treated with Therapeutic Reduction Mammoplasty Versus Mastectomy with Immediate Reconstruction.

Michael J Stein, Aneesh Karir, Angel Arnaout, Amanda Roberts, Erin Cordeiro, Tinghua Zhang, Jing Zhang,

BACKGROUND:Therapeutic reduction mammoplasty (TRM) is a safe and effective surgical technique that has oncologic outcomes comparable with those achieved by mastectomy. This study aimed to compare surgical and patient-reported outcomes between breast cancer patients treated with TRM and those who had mastectomy with immediate reconstruction (MIR). METHODS:A 4-year, single-institution, retrospective ... Read more >>

Ann. Surg. Oncol. (Annals of surgical oncology)
[2020, :]

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The Landmark Series: Gallbladder Cancer.

Adriana C Gamboa, Shishir K Maithel,

Given the rarity of gallbladder carcinoma, level I evidence to guide the multimodal treatment of this disease is lacking. Since 2010, four randomized phase III clinical trials including ABC-02, PRODIGE-12/ACCORD-18, BILCAP, and BCAT, and a single-arm phase II trial (SWOG0809) have been reported on the use of adjuvant strategies for ... Read more >>

Ann. Surg. Oncol. (Annals of surgical oncology)
[2020, :]

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Mixed Response to Immunotherapy in Patients with Metastatic Melanoma.

Daan Jan Willem Rauwerdink, George Molina, Dennie Tompers Frederick, Tanya Sharova, Jos van der Hage, Sonia Cohen, Genevieve Marie Boland,

BACKGROUND:Immunotherapy has improved overall survival in metastatic melanoma. Response to therapy can be difficult to evaluate as the traditionally used RECIST 1.1 criteria do not capture heterogeneous responses. Here we describe the clinical characterization of melanoma patients with a clinically defined mixed response to immunotherapy. METHODS:This was a single institution, ... Read more >>

Ann. Surg. Oncol. (Annals of surgical oncology)
[2020, :]

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ASO Author Reflections: Transitioning From Morphology to Transcriptomics in Capturing Tumor Biology.

Hideo Takahashi, Masanori Oshi, Mariko Asaoka, Takashi Ishikawa, Itaru Endo, Kazuaki Takabe,

Ann. Surg. Oncol. (Annals of surgical oncology)
[2020, :]

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ASO Authors Reflections: Patient Age and Survival After Surgery for Esophageal Cancer.

Giola Santoni, Jesper Lagergren, Matteo Bottai,

Ann. Surg. Oncol. (Annals of surgical oncology)
[2020, :]

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